Structural determinants in phycotoxins and AChBP conferring high affinity binding and nicotinic AChR antagonism
Bourne, Yves, Radić, Zoran, Aráoz, Rómulo, Talley, Todd T, Benoit, Evelyne, Servent, Denis, Taylor, Palmer, Molgó, Jordi, Marchot, Pascale
Published in Proceedings of the National Academy of Sciences - PNAS (30.03.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (30.03.2010)
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Interactions of Nereistoxin and Its Analogs with Vertebrate Nicotinic Acetylcholine Receptors and Molluscan ACh Binding Proteins
Kem, William R, Andrud, Kristin, Bruno, Galen, Xing, Hong, Soti, Ferenc, Talley, Todd T, Taylor, Palmer
Published in Marine drugs (04.01.2022)
Published in Marine drugs (04.01.2022)
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Atomic interactions of neonicotinoid agonists with AChBP: Molecular recognition of the distinctive electronegative pharmacophore
Talley, Todd T, Harel, Michal, Hibbs, Ryan E, Radić, Zoran, Tomizawa, Motohiro, Casida, John E, Taylor, Palmer
Published in Proceedings of the National Academy of Sciences - PNAS (27.05.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (27.05.2008)
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Atypical nicotinic agonist bound conformations conferring subtype selectivity
Tomizawa, Motohiro, Maltby, David, Talley, Todd T, Durkin, Kathleen A, Medzihradszky, Katalin F, Burlingame, Alma L, Taylor, Palmer, Casida, John E
Published in Proceedings of the National Academy of Sciences - PNAS (05.02.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (05.02.2008)
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A phase II clinical study of 13‐deoxy, 5‐iminodoxorubicin (GPX‐150) with metastatic and unresectable soft tissue sarcoma
Van Tine, Brian A., Agulnik, Mark, Olson, Richard D., Walsh, Gerald M., Klausner, Arthur, Frank, Nicole E., Talley, Todd T., Milhem, Mohammed M.
Published in Cancer medicine (Malden, MA) (01.06.2019)
Published in Cancer medicine (Malden, MA) (01.06.2019)
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Mapping the elusive neonicotinoid binding site
Tomizawa, Motohiro, Talley, Todd T, Maltby, David, Durkin, Kathleen A, Medzihradszky, Katalin F, Burlingame, Alma L, Taylor, Palmer, Casida, John E
Published in Proceedings of the National Academy of Sciences - PNAS (22.05.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (22.05.2007)
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The effect of crebanine on memory and cognition impairment via the alpha-7 nicotinic acetylcholine receptor
Rojsanga, Piyanuch, Boonyarat, Chantana, Utsintong, Maleeruk, Nemecz, Ákos, Yamauchi, John G., Talley, Todd T., Olson, Arthur J., Matsumoto, Kinzo, Vajragupta, Opa
Published in Life sciences (1973) (21.08.2012)
Published in Life sciences (1973) (21.08.2012)
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Structure-guided drug design: Conferring selectivity among neuronal nicotinic receptor and acetylcholine-binding protein subtypes
Taylor, Palmer, Talley, Todd T., Radic’, Zoran, Hansen, Scott B., Hibbs, Ryan E., Shi, Jian
Published in Biochemical pharmacology (15.10.2007)
Published in Biochemical pharmacology (15.10.2007)
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Defining Nicotinic Agonist Binding Surfaces through Photoaffinity Labeling
Tomizawa, Motohiro, Maltby, David, Medzihradszky, Katalin F, Zhang, Nanjing, Durkin, Kathleen A, Presley, Jack, Talley, Todd T, Taylor, Palmer, Burlingame, Alma L, Casida, John E
Published in Biochemistry (Easton) (31.07.2007)
Published in Biochemistry (Easton) (31.07.2007)
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Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal α7 nicotinic acetylcholine receptor
Hibbs, Ryan E, Sulzenbacher, Gerlind, Shi, Jianxin, Talley, Todd T, Conrod, Sandrine, Kem, William R, Taylor, Palmer, Marchot, Pascale, Bourne, Yves
Published in The EMBO journal (07.10.2009)
Published in The EMBO journal (07.10.2009)
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Natural Variation within the Neuronal Nicotinic Acetylcholine Receptor Cluster on Human Chromosome 15q24: Influence on Heritable Autonomic Traits in Twin Pairs
Rana, Brinda K, Wessel, Jennifer, Mahboubi, Vafa, Rao, Fangwen, Haeller, Jeannine, Gayen, Jiaur R, Eskin, Eleazar, Valle, Anne M, Das, Madhusudan, Mahata, Sushil K, Taupenot, Laurent, Stridsberg, Mats, Talley, Todd T, Ziegler, Michael G, Smith, Douglas W, Schork, Nicholas J, O'Connor, Daniel T, Taylor, Palmer
Published in The Journal of pharmacology and experimental therapeutics (01.11.2009)
Published in The Journal of pharmacology and experimental therapeutics (01.11.2009)
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Inhibition of Acetylcholinesterases by Stereoisomeric Organophosphorus Compounds Containing Both Thioester and p‑Nitrophenyl Leaving Groups
Talley, Todd T, Chao, Chih-kai, Berkman, Clifford E, Richardson, Rudy J, Thompson, Charles M
Published in Chemical research in toxicology (21.09.2020)
Published in Chemical research in toxicology (21.09.2020)
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Generation of Candidate Ligands for Nicotinic Acetylcholine Receptors via in situ Click Chemistry with a Soluble Acetylcholine Binding Protein Template
Grimster, Neil P., Stump, Bernhard, Fotsing, Joseph R., Weide, Timo, Talley, Todd T., Yamauchi, John G., Nemecz, Ákos, Kim, Choel, Ho, Kwok-Yiu, Sharpless, K. Barry, Taylor, Palmer, Fokin, Valery V.
Published in Journal of the American Chemical Society (18.04.2012)
Published in Journal of the American Chemical Society (18.04.2012)
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Molecular determinants of α-conotoxin potency for inhibition of human and rat α6β4 nicotinic acetylcholine receptors
Hone, Arik J., Talley, Todd T., Bobango, Janet, Huidobro Melo, Cesar, Hararah, Fuaad, Gajewiak, Joanna, Christensen, Sean, Harvey, Peta J., Craik, David J., McIntosh, J. Michael
Published in The Journal of biological chemistry (16.11.2018)
Published in The Journal of biological chemistry (16.11.2018)
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Comparative effects of doxorubicin and a doxorubicin analog, 13-deoxy, 5-iminodoxorubicin (GPX-150), on human topoisomerase IIβ activity and cardiac function in a chronic rabbit model
Frank, Nicole E., Cusack, Barry J., Talley, Todd T., Walsh, Gerald M., Olson, Richard D.
Published in Investigational new drugs (01.12.2016)
Published in Investigational new drugs (01.12.2016)
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