Neutral Lipid Cacostasis Contributes to Disease Pathogenesis in Amyotrophic Lateral Sclerosis
Dodge, James C, Jensen, Elizabeth H, Yu, Jinlong, Sardi, S Pablo, Bialas, Allison R, Taksir, Tatyana V, Bangari, Dinesh S, Shihabuddin, Lamya S
Published in The Journal of neuroscience (18.11.2020)
Published in The Journal of neuroscience (18.11.2020)
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Metabolic signatures of amyotrophic lateral sclerosis reveal insights into disease pathogenesis
Dodge, James C., Treleaven, Christopher M., Fidler, Jonathan A., Tamsett, Thomas J., Bao, Channa, Searles, Michelle, Taksir, Tatyana V., Misra, Kuma, Sidman, Richard L., Cheng, Seng H., Shihabuddin, Lamya S.
Published in Proceedings of the National Academy of Sciences - PNAS (25.06.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (25.06.2013)
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AAV4-mediated Expression of IGF-1 and VEGF Within Cellular Components of the Ventricular System Improves Survival Outcome in Familial ALS Mice
Dodge, James C, Treleaven, Christopher M, Fidler, Jonathan A, Hester, Mark, Haidet, Amanda, Handy, Chalonda, Rao, Meghan, Eagle, Amy, Matthews, Jennifer C, Taksir, Tatyana V, Cheng, Seng H, Shihabuddin, Lamya S, Kaspar, Brian K
Published in Molecular therapy (01.12.2010)
Published in Molecular therapy (01.12.2010)
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Glucosylceramide synthase inhibition reduces ganglioside GM3 accumulation, alleviates amyloid neuropathology, and stabilizes remote contextual memory in a mouse model of Alzheimer's disease
Dodge, James C, Tamsett, Thomas J, Treleaven, Christopher M, Taksir, Tatyana V, Piepenhagen, Peter, Sardi, S Pablo, Cheng, Seng H, Shihabuddin, Lamya S
Published in Alzheimer's research & therapy (01.02.2022)
Published in Alzheimer's research & therapy (01.02.2022)
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Journal Article
Delivery of AAV-IGF-1 to the CNS Extends Survival in ALS Mice Through Modification of Aberrant Glial Cell Activity
Dodge, James C, Haidet, Amanda M, Yang, Wendy, Passini, Marco A, Hester, Mark, Clarke, Jennifer, Roskelley, Eric M, Treleaven, Christopher M, Rizo, Liza, Martin, Heather, Kim, Soo H, Kaspar, Rita, Taksir, Tatyana V, Griffiths, Denise A, Cheng, Seng H, Shihabuddin, Lamya S, Kaspar, Brian K
Published in Molecular therapy (01.06.2008)
Published in Molecular therapy (01.06.2008)
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Journal Article
Combination Brain and Systemic Injections of AAV Provide Maximal Functional and Survival Benefits in the Niemann-Pick Mouse
Passini, Marco A., Bu, Jie, Fidler, Jonathan A., Ziegler, Robin J., Foley, Joseph W., Dodge, James C., Yang, Wendy W., Clarke, Jennifer, Taksir, Tatyana V., Griffiths, Denise A., Zhao, Michael A., O'Riordan, Catherine R., Schuchman, Edward H., Shihabuddin, Lamya S., Cheng, Seng H.
Published in Proceedings of the National Academy of Sciences - PNAS (29.05.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (29.05.2007)
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Journal Article
Gene Transfer of Human Acid Sphingomyelinase Corrects Neuropathology and Motor Deficits in a Mouse Model of Niemann-Pick Type A Disease
James C. Dodge, Jennifer Clarke, Antonius Song, Jie Bu, Yang, Wendy, Tatyana V. Taksir, Denise Griffiths, Michael A. Zhao, Schuchman, Edward H., Cheng, Seng H., Catherine R. O'Riordan, Shihabuddin, Lamya S., Marco A. Passini, Stewart, Gregory R.
Published in Proceedings of the National Academy of Sciences - PNAS (06.12.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (06.12.2005)
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Optimization of a Histopathological Biomarker for Sphingomyelin Accumulation in Acid Sphingomyelinase Deficiency
Taksir, Tatyana V., Johnson, Jennifer, Maloney, Colleen L., Yandl, Emily, Griffiths, Denise, Thurberg, Beth L., Ryan, Susan
Published in The journal of histochemistry and cytochemistry (01.08.2012)
Published in The journal of histochemistry and cytochemistry (01.08.2012)
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Comparative analysis of acid sphingomyelinase distribution in the CNS of rats and mice following intracerebroventricular delivery
Treleaven, Christopher M, Tamsett, Thomas, Fidler, Jonathan A, Taksir, Tatyana V, Cheng, Seng H, Shihabuddin, Lamya S, Dodge, James C
Published in PloS one (25.01.2011)
Published in PloS one (25.01.2011)
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Journal Article
AAV Vector-Mediated Correction of Brain Pathology in a Mouse Model of Niemann–Pick A Disease
Passini, Marco A., Macauley, Shannon L., Huff, Michael R., Taksir, Tatyana V., Bu, Jie, Wu, I-Huan, Piepenhagen, Peter A., Dodge, James C., Shihabuddin, Lamya S., O'Riordan, Catherine R., Schuchman, Edward H., Stewart, Gregory R.
Published in Molecular therapy (01.05.2005)
Published in Molecular therapy (01.05.2005)
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Intracerebroventricular infusion of acid sphingomyelinase corrects CNS manifestations in a mouse model of Niemann–Pick A disease
Dodge, James C., Clarke, Jennifer, Treleaven, Christopher M., Taksir, Tatyana V., Griffiths, Denise A., Yang, Wendy, Fidler, Jonathan A., Passini, Marco A., Karey, Kenneth P., Schuchman, Edward H., Cheng, Seng H., Shihabuddin, Lamya S.
Published in Experimental neurology (01.02.2009)
Published in Experimental neurology (01.02.2009)
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Journal Article
Relationship between neuropathology and disease progression in the SOD1(G93A) ALS mouse
Yang, Wendy W, Sidman, Richard L, Taksir, Tatyana V, Treleaven, Christopher M, Fidler, Jonathan A, Cheng, Seng H, Dodge, James C, Shihabuddin, Lamya S
Published in Experimental neurology (01.02.2011)
Published in Experimental neurology (01.02.2011)
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Journal Article
Relationship between neuropathology and disease progression in the SOD1G93A ALS mouse
YANG, Wendy W, SIDMAN, Richard L, TAKSIR, Tatyana V, TRELEAVEN, Christopher M, FIDLER, Jonathan A, CHENG, Seng H, DODGE, James C, SHIHABUDDIN, Lamya S
Published in Experimental neurology (01.02.2011)
Published in Experimental neurology (01.02.2011)
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Ability of adeno-associated virus serotype 8-mediated hepatic expression of acid alpha-glucosidase to correct the biochemical and motor function deficits of presymptomatic and symptomatic Pompe mice
Ziegler, Robin J, Bercury, Scott D, Fidler, Jonathan, Zhao, Michael A, Foley, Joseph, Taksir, Tatyana V, Ryan, Susan, Hodges, Bradley L, Scheule, Ronald K, Shihabuddin, Lamya S, Cheng, Seng H
Published in Human gene therapy (01.06.2008)
Published in Human gene therapy (01.06.2008)
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Optimized Preservation of CNS Morphology for the Identification of Glycogen in the Pompe Mouse Model
Taksir, Tatyana V, Griffiths, Denise, Johnson, Jennifer, Ryan, Susan, Shihabuddin, Lamya S, Thurberg, Beth L
Published in The journal of histochemistry and cytochemistry (01.10.2007)
Published in The journal of histochemistry and cytochemistry (01.10.2007)
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Journal Article
Intraparenchymal injections of acid sphingomyelinase results in regional correction of lysosomal storage pathology in the Niemann–Pick A mouse
Yang, Wendy W., Dodge, James C., Passini, Marco A., Taksir, Tatyana V., Griffiths, Denise, Schuchman, Edward H., Cheng, Seng H., Shihabuddin, Lamya S.
Published in Experimental neurology (01.10.2007)
Published in Experimental neurology (01.10.2007)
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Journal Article
2. Identification of Different Modes of Viral Transport in the Non-Human Primate Brain after Convection-Enhanced Delivery of AAV Serotype Vectors
Passini, Marco A., Bu, Jie, Dodge, James C., Shihabuddin, Lamya S., Taksir, Tatyana V., Griffiths, Denise A., Bringas, John, Hadaczek, Piotr, Avramut, Mihaela, Cheng, Seng H., Bankiewicz, Krystof
Published in Molecular therapy (01.05.2006)
Published in Molecular therapy (01.05.2006)
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Journal Article
1062. Intracerebellar Injection of AAV-IGF-1 Improves Motor Function and Extends Survival in a Mouse Model of Amyotrophic Lateral Sclerosis
Dodge, James C., Passini, Marco A., Clarke, Jennifer, Grissett, Liza, Kim, Soo Hyun, Wen, Rita, Taksir, Tatyana V., Griffiths, Denise A., Cheng, Seng H., Kaspar, Brian K., Shihabuddin, Lamya S.
Published in Molecular therapy (01.05.2006)
Published in Molecular therapy (01.05.2006)
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Journal Article
Mouse neural progenitor cells differentiate into oligodendrocytes in the brain of a knockout mouse model of Canavan disease
Surendran, Sankar, Shihabuddin, Lamya S., Clarke, Jennifer, Taksir, Tatyana V., Stewart, Gregory R., Parsons, Geoffrey, Yang, Wendy, Tyring, Stephen K., Michals-Matalon, Kimberlee, Matalon, Reuben
Published in Brain research. Developmental brain research (15.10.2004)
Published in Brain research. Developmental brain research (15.10.2004)
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Journal Article
Relationship between neuropathology and disease progression in the SOD1 super(G93A) ALS mouse
Yang, Wendy W, Sidman, Richard L, Taksir, Tatyana V, Treleaven, Christopher M, Fidler, Jonathan A, Cheng, Seng H, Dodge, James C, Shihabuddin, Lamya S
Published in Experimental neurology (01.02.2011)
Published in Experimental neurology (01.02.2011)
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