The effects of selective antagonists of serotonin 5-HT7 and 5-HT1A receptors on MK-801-induced impairment of learning and memory in the passive avoidance and Morris water maze tests in rats: Mechanistic implications for the beneficial effects of the novel atypical antipsychotic lurasidone
HORISAWA, Tomoko, ISHIBASHI, Tadashi, NISHIKAWA, Hiroyuki, ENOMOTO, Takeshi, TOMA, Satoko, ISHIYAMA, Takeo, TAIJI, Mutsuo
Published in Behavioural brain research (20.06.2011)
Published in Behavioural brain research (20.06.2011)
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The role of 5-HT7 receptor antagonism in the amelioration of MK-801-induced learning and memory deficits by the novel atypical antipsychotic drug lurasidone
Horisawa, Tomoko, Nishikawa, Hiroyuki, Toma, Satoko, Ikeda, Atsushi, Horiguchi, Masakuni, Ono, Michiko, Ishiyama, Takeo, Taiji, Mutsuo
Published in Behavioural brain research (01.05.2013)
Published in Behavioural brain research (01.05.2013)
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Binding of lurasidone, a novel antipsychotic, to rat 5-HT7 receptor: Analysis by [3H]SB-269970 autoradiography
Horisawa, Tomoko, Ishiyama, Takeo, Ono, Michiko, Ishibashi, Tadashi, Taiji, Mutsuo
Published in Progress in neuro-psychopharmacology & biological psychiatry (10.01.2013)
Published in Progress in neuro-psychopharmacology & biological psychiatry (10.01.2013)
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Effects of lurasidone on executive function in common marmosets
Murai, Takeshi, Nakako, Tomokazu, Ikejiri, Masaru, Ishiyama, Takeo, Taiji, Mutsuo, Ikeda, Kazuhito
Published in Behavioural brain research (01.06.2013)
Published in Behavioural brain research (01.06.2013)
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Journal Article
Design, synthesis and structure–activity relationships of novel benzoxazolone derivatives as 18kDa translocator protein (TSPO) ligands
Fukaya, Takayuki, Kodo, Toru, Ishiyama, Takeo, Kakuyama, Hiroyoshi, Nishikawa, Hiroyuki, Baba, Satoko, Masumoto, Shuji
Published in Bioorganic & medicinal chemistry (01.09.2012)
Published in Bioorganic & medicinal chemistry (01.09.2012)
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P3-23 A unique effect of lurasidone on the cognitive function in object retrieval with detours, a test of the executive function in non-human primates
Tomokazu Nakako, Takeshi Murai, Masaru Ikejiri, Takeo Ishiyama, Kazuhito Ikeda, Mutsuo Taiji
Published in Journal of Pharmacological Sciences (15.03.2013)
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Published in Journal of Pharmacological Sciences (15.03.2013)
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Neuropsychopharmacology renaissance in Japan: A new era after the crisis
Ozaki, Norio, Kimura, Teiji, Kikuchi, Tetsuro, Ishiyama, Takeo
Published in Psychiatry and clinical neurosciences (01.07.2023)
Published in Psychiatry and clinical neurosciences (01.07.2023)
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EPI-589, a redox-active neuroprotectant, potently protects cultured cells from oxidative stress and alleviates symptomatic and pathological progression of motor neuron disease in the wobbler mouse
Matsumoto, Yuji, Sampei, Kazuaki, Nashida, Tetsuaki, Fujii, Yuta, Tani, Naoko, Ishibashi, Fumiaki, Yamanaka, Mitsugu, Ishiyama, Takeo
Published in bioRxiv (14.03.2022)
Published in bioRxiv (14.03.2022)
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Paper
Pharmacological profile of lurasidone, a novel antipsychotic agent with potent 5-hydroxytryptamine 7 (5-HT7) and 5-HT1A receptor activity
Ishibashi, Tadashi, Horisawa, Tomoko, Tokuda, Kumiko, Ishiyama, Takeo, Ogasa, Masaaki, Tagashira, Rie, Matsumoto, Kenji, Nishikawa, Hiroyuki, Ueda, Yoko, Toma, Satoko, Oki, Hitomi, Tanno, Norihiko, Saji, Ikutaro, Ito, Akira, Ohno, Yukihiro, Nakamura, Mitsutaka
Published in The Journal of pharmacology and experimental therapeutics (01.07.2010)
Published in The Journal of pharmacology and experimental therapeutics (01.07.2010)
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Lurasidone (SM-13496), a novel atypical antipsychotic drug, reverses MK-801-induced impairment of learning and memory in the rat passive-avoidance test
Ishiyama, Takeo, Tokuda, Kumiko, Ishibashi, Tadashi, Ito, Akira, Toma, Satoko, Ohno, Yukihiro
Published in European journal of pharmacology (31.10.2007)
Published in European journal of pharmacology (31.10.2007)
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Journal Article
Design, synthesis and structure-activity relationships of novel benzoxazolone derivatives as 18 kDa translocator protein (TSPO) ligands
Fukaya, Takayuki, Kodo, Toru, Ishiyama, Takeo, Kakuyama, Hiroyoshi, Nishikawa, Hiroyuki, Baba, Satoko, Masumoto, Shuji
Published in Bioorganic & medicinal chemistry (15.09.2012)
Published in Bioorganic & medicinal chemistry (15.09.2012)
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Journal Article
Lurasidone reverses MK-801-induced impairment of learning and memory in the Morris water maze and radial-arm maze tests in rats
Enomoto, Takeshi, Ishibashi, Tadashi, Tokuda, Kumiko, Ishiyama, Takeo, Toma, Satoko, Ito, Akira
Published in Behavioural brain research (25.01.2008)
Published in Behavioural brain research (25.01.2008)
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Design, synthesis and structure-activity relationship of novel tricyclic benzimidazolone derivatives as potent 18 kDa translocator protein (TSPO) ligands
Fukaya, Takayuki, Kodo, Toru, Ishiyama, Takeo, Nishikawa, Hiroyuki, Baba, Satoko, Masumoto, Shuji
Published in Bioorganic & medicinal chemistry (01.03.2013)
Published in Bioorganic & medicinal chemistry (01.03.2013)
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Journal Article
Genetic Transfer of the Wobbler Gene to a C57BL/6J × NZB Hybrid Stock: Natural History of the Motor Neuron Disease and Response to CNTF and BDNF Cotreatment
Ishiyama, Takeo, Klinkosz, Bogdan, Pioro, Erik P., Mitsumoto, Hiroshi
Published in Experimental neurology (01.11.1997)
Published in Experimental neurology (01.11.1997)
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Journal Article
Design, synthesis and structure–activity relationship of novel tricyclic benzimidazolone derivatives as potent 18kDa translocator protein (TSPO) ligands
Fukaya, Takayuki, Kodo, Toru, Ishiyama, Takeo, Nishikawa, Hiroyuki, Baba, Satoko, Masumoto, Shuji
Published in Bioorganic & medicinal chemistry (01.03.2013)
Published in Bioorganic & medicinal chemistry (01.03.2013)
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Journal Article
The effects of selective antagonists of serotonin 5-HT 7 and 5-HT 1A receptors on MK-801-induced impairment of learning and memory in the passive avoidance and Morris water maze tests in rats: Mechanistic implications for the beneficial effects of the novel atypical antipsychotic lurasidone
Horisawa, Tomoko, Ishibashi, Tadashi, Nishikawa, Hiroyuki, Enomoto, Takeshi, Toma, Satoko, Ishiyama, Takeo, Taiji, Mutsuo
Published in Behavioural brain research (2011)
Published in Behavioural brain research (2011)
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Journal Article
Riluzole slows the progression of neuromuscular dysfunction in the wobbler mouse motor neuron disease
Ishiyama, Takeo, Okada, Reiko, Nishibe, Hironori, Mitsumoto, Hiroshi, Nakayama, Chikao
Published in Brain research (03.09.2004)
Published in Brain research (03.09.2004)
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