The flavonoid apigenin inhibits hepatitis C virus replication by decreasing mature microRNA122 levels
Shibata, Chikako, Ohno, Motoko, Otsuka, Motoyuki, Kishikawa, Takahiro, Goto, Kaku, Muroyama, Ryosuke, Kato, Naoya, Yoshikawa, Takeshi, Takata, Akemi, Koike, Kazuhiko
Published in Virology (New York, N.Y.) (01.08.2014)
Published in Virology (New York, N.Y.) (01.08.2014)
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Journal Article
MicroRNAs and liver disease
Otsuka, Motoyuki, Kishikawa, Takahiro, Yoshikawa, Takeshi, Yamagami, Mari, Ohno, Motoko, Takata, Akemi, Shibata, Chikako, Ishibashi, Rei, Koike, Kazuhiko
Published in Journal of human genetics (01.01.2017)
Published in Journal of human genetics (01.01.2017)
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Journal Article
Mutual antagonism between hepatitis B viral mRNA and host microRNA let-7
Takata, Akemi, Otsuka, Motoyuki, Ohno, Motoko, Kishikawa, Takahiro, Yoshikawa, Takeshi, Koike, Kazuhiko
Published in Scientific reports (16.03.2016)
Published in Scientific reports (16.03.2016)
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Journal Article
Repression of MicroRNA Function Mediates Inflammation-associated Colon Tumorigenesis
Yoshikawa, Takeshi, Wu, Jianfeng, Otsuka, Motoyuki, Kishikawa, Takahiro, Suzuki, Nobumi, Takata, Akemi, Ohno, Motoko, Ishibashi, Rei, Yamagami, Mari, Nakagawa, Ryo, Kato, Naoya, Miyazawa, Masaaki, Han, Jiahuai, Koike, Kazuhiko
Published in Gastroenterology (New York, N.Y. 1943) (01.02.2017)
Published in Gastroenterology (New York, N.Y. 1943) (01.02.2017)
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The flavonoid apigenin improves glucose tolerance through inhibition of microRNA maturation in miRNA103 transgenic mice
Ohno, Motoko, Shibata, Chikako, Kishikawa, Takahiro, Yoshikawa, Takeshi, Takata, Akemi, Kojima, Kentaro, Akanuma, Masao, Kang, Young Jun, Yoshida, Haruhiko, Otsuka, Motoyuki, Koike, Kazuhiko
Published in Scientific reports (30.08.2013)
Published in Scientific reports (30.08.2013)
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Journal Article
Regulation of the expression of the liver cancer susceptibility gene MICA by microRNAs
Kishikawa, Takahiro, Otsuka, Motoyuki, Yoshikawa, Takeshi, Ohno, Motoko, Takata, Akemi, Shibata, Chikako, Kondo, Yuji, Akanuma, Masao, Yoshida, Haruhiko, Koike, Kazuhiko
Published in Scientific reports (24.09.2013)
Published in Scientific reports (24.09.2013)
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Journal Article
Unique haploinsufficient role of the microRNA-processing molecule Dicer1 in a murine colitis-associated tumorigenesis model
Yoshikawa, Takeshi, Otsuka, Motoyuki, Kishikawa, Takahiro, Takata, Akemi, Ohno, Motoko, Shibata, Chikako, Kang, Young Jun, Yoshida, Haruhiko, Koike, Kazuhiko
Published in PloS one (02.09.2013)
Published in PloS one (02.09.2013)
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Journal Article
Inhibition of microRNA122 decreases SREBP1 expression by modulating suppressor of cytokine signaling 3 expression
Shibata, Chikako, Kishikawa, Takahiro, Otsuka, Motoyuki, Ohno, Motoko, Yoshikawa, Takeshi, Takata, Akemi, Yoshida, Haruhiko, Koike, Kazuhiko
Published in Biochemical and biophysical research communications (16.08.2013)
Published in Biochemical and biophysical research communications (16.08.2013)
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Journal Article
ROCK inhibition enhances microRNA function by promoting deadenylation of targeted mRNAs via increasing PAIP2 expression
Yoshikawa, Takeshi, Wu, Jianfeng, Otsuka, Motoyuki, Kishikawa, Takahiro, Ohno, Motoko, Shibata, Chikako, Takata, Akemi, Han, Felicia, Kang, Young Jun, Chen, Chyi-Ying A, Shyu, Ann-Bin, Han, Jiahuai, Koike, Kazuhiko
Published in Nucleic acids research (03.09.2015)
Published in Nucleic acids research (03.09.2015)
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Journal Article
RASAL1 is a potent regulator of hepatic stellate cell activity and liver fibrosis
Takata, Akemi, Otsuka, Motoyuki, Kishikawa, Takahiro, Yamagami, Mari, Ishibashi, Rei, Sekiba, Kazuma, Suzuki, Tatsunori, Ohno, Motoko, Yamashita, Yui, Abe, Takaya, Masuzaki, Ryota, Ikenoue, Tsuneo, Koike, Kazuhiko
Published in Oncotarget (12.09.2017)
Published in Oncotarget (12.09.2017)
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Journal Article
Receptor for activated protein kinase C: requirement for efficient microRNA function and reduced expression in hepatocellular carcinoma
Otsuka, Motoyuki, Takata, Akemi, Yoshikawa, Takeshi, Kojima, Kentaro, Kishikawa, Takahiro, Shibata, Chikako, Takekawa, Mutsuhiro, Yoshida, Haruhiko, Omata, Masao, Koike, Kazuhiko
Published in PloS one (15.09.2011)
Published in PloS one (15.09.2011)
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Journal Article
Direct differentiation of hepatic cells from human induced pluripotent stem cells using a limited number of cytokines
Takata, Akemi, Otsuka, Motoyuki, Kogiso, Tomomi, Kojima, Kentaro, Yoshikawa, Takeshi, Tateishi, Ryosuke, Kato, Naoya, Shiina, Shuichiro, Yoshida, Haruhiko, Omata, Masao, Koike, Kazuhiko
Published in Hepatology international (01.12.2011)
Published in Hepatology international (01.12.2011)
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Journal Article
Current status of miRNA-targeting therapeutics and preclinical studies against gastroenterological carcinoma
Shibata, Chikako, Otsuka, Motoyuki, Kishikawa, Takahiro, Yoshikawa, Takeshi, Ohno, Motoko, Takata, Akemi, Koike, Kazuhiko
Published in Molecular and cellular therapies (13.12.2013)
Published in Molecular and cellular therapies (13.12.2013)
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Journal Article
Circulating RNAs as new biomarkers for detecting pancreatic cancer
Kishikawa, Takahiro, Otsuka, Motoyuki, Ohno, Motoko, Yoshikawa, Takeshi, Takata, Akemi, Koike, Kazuhiko
Published in World journal of gastroenterology : WJG (28.07.2015)
Published in World journal of gastroenterology : WJG (28.07.2015)
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Journal Article
MicroRNA‐140 acts as a liver tumor suppressor by controlling NF‐κB activity by directly targeting DNA methyltransferase 1 (Dnmt1) expression
Takata, Akemi, Otsuka, Motoyuki, Yoshikawa, Takeshi, Kishikawa, Takahiro, Hikiba, Yohko, Obi, Shuntaro, Goto, Tadashi, Kang, Young Jun, Maeda, Shin, Yoshida, Haruhiko, Omata, Masao, Asahara, Hiroshi, Koike, Kazuhiko
Published in Hepatology (Baltimore, Md.) (01.01.2013)
Published in Hepatology (Baltimore, Md.) (01.01.2013)
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Journal Article
MicroRNA-22 and microRNA-140 suppress NF-κB activity by regulating the expression of NF-κB coactivators
Takata, Akemi, Otsuka, Motoyuki, Kojima, Kentaro, Yoshikawa, Takeshi, Kishikawa, Takahiro, Yoshida, Haruhiko, Koike, Kazuhiko
Published in Biochemical and biophysical research communications (12.08.2011)
Published in Biochemical and biophysical research communications (12.08.2011)
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Journal Article
Silencing of microRNA-122 enhances interferon-α signaling in the liver through regulating SOCS3 promoter methylation
Yoshikawa, Takeshi, Takata, Akemi, Otsuka, Motoyuki, Kishikawa, Takahiro, Kojima, Kentaro, Yoshida, Haruhiko, Koike, Kazuhiko
Published in Scientific reports (06.09.2012)
Published in Scientific reports (06.09.2012)
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Journal Article
MicroRNA122 is a key regulator of α-fetoprotein expression and influences the aggressiveness of hepatocellular carcinoma
Kojima, Kentaro, Takata, Akemi, Vadnais, Charles, Otsuka, Motoyuki, Yoshikawa, Takeshi, Akanuma, Masao, Kondo, Yuji, Kang, Young Jun, Kishikawa, Takahiro, Kato, Naoya, Xie, Zhifang, Zhang, Weiping J., Yoshida, Haruhiko, Omata, Masao, Nepveu, Alain, Koike, Kazuhiko
Published in Nature communications (07.06.2011)
Published in Nature communications (07.06.2011)
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