Protection afforded by pre- or post-treatment with 4-phenylbutyrate against liver injury induced by acetaminophen overdose in mice
Shimizu, Daisuke, Ishitsuka, Yoichi, Miyata, Keishi, Tomishima, Yoshiro, Kondo, Yuki, Irikura, Mitsuru, Iwawaki, Takao, Oike, Yuichi, Irie, Tetsumi
Published in Pharmacological research (01.09.2014)
Published in Pharmacological research (01.09.2014)
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Constitutive role of GADD34 and CReP in cancellation of phospho-eIF2[alpha]-dependent translational attenuation and insulin biosynthesis in pancreatic [beta] cells
Akai, Ryoko, Hosoda, Akira, Yoshino, Mayuko, Iwawaki, Takao
Published in Genes to cells : devoted to molecular & cellular mechanisms (01.11.2015)
Published in Genes to cells : devoted to molecular & cellular mechanisms (01.11.2015)
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Constitutive role of GADD 34 and CR eP in cancellation of phospho‐ eIF 2α‐dependent translational attenuation and insulin biosynthesis in pancreatic β cells
Akai, Ryoko, Hosoda, Akira, Yoshino, Mayuko, Iwawaki, Takao
Published in Genes to cells : devoted to molecular & cellular mechanisms (01.11.2015)
Published in Genes to cells : devoted to molecular & cellular mechanisms (01.11.2015)
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Comparative analysis of ER stress response into HIV protease inhibitors: Lopinavir but not darunavir induces potent ER stress response via ROS/JNK pathway
Taura, Manabu, Kariya, Ryusho, Kudo, Eriko, Goto, Hiroki, Iwawaki, Takao, Amano, Masayuki, Suico, Mary Ann, Kai, Hirofumi, Mitsuya, Hiroaki, Okada, Seiji
Published in Free radical biology & medicine (01.12.2013)
Published in Free radical biology & medicine (01.12.2013)
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Journal Article
Protein Quality Control Through Endoplasmic Reticulum-Associated Degradation Maintains Hematopoietic Stem Cell Identity and Niche Interactions
Xu, Longyong, Liu, Xia, Peng, Fanglue, Zhang, Weijie, Zheng, Liting, Ding, Yao, Gu, Tianpeng, Lv, Kaosheng, Wang, Jin, Ortinau, Laura, Hu, Tianyuan, Shi, Xiangguo, Shi, Guojun, Shang, Ge, Sun, Shengyi, Iwawaki, Takao, Ji, Yewei, Li, Wei, Rosen, Jeffrey M., Zhang, Xiang H.-F., Park, Dongsu, Adoro, Stanley, Catic, Andre, Tong, Wei, Qi, Ling, Nakada, Daisuke, Chen, Xi
Published in Nature cell biology (21.09.2020)
Published in Nature cell biology (21.09.2020)
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N-RasG12D-Mediated Dysregulation of IRE1alpha-Xbp1s Signaling Promotes Pre-Leukemic Hematopoietic Stem Cell Expansion
Liu, Lu, Zhao, Meiling, Yang, Kevin B, Jin, Xi, Ney, Gina, Del Valle, Juan, Iwawaki, Takao, Li, Qing
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
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IRE1[alpha]/XBP1-mediated branch of the unfolded protein response regulates osteoclastogenesis
Tohmonda, Takahide, Yoda, Masaki, Iwawaki, Takao, Matsumoto, Morio, Nakamura, Masaya, Mikoshiba, Katsuhiko, Toyama, Yoshiaki, Horiuchi, Keisuke
Published in The Journal of clinical investigation (01.08.2015)
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Published in The Journal of clinical investigation (01.08.2015)
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Transgenic mouse model for imaging of interleukin-1β-related inflammation in vivo
Iwawaki, Takao, Akai, Ryoko, Oikawa, Daisuke, Toyoshima, Takae, Yoshino, Mayuko, Suzuki, Mitsumi, Takeda, Naoki, Ishikawa, Tomo-o, Kataoka, Yosky, Yamamura, Ken-ichi
Published in Scientific reports (24.11.2015)
Published in Scientific reports (24.11.2015)
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Real-time in vivo imaging reveals localised Nrf2 stress responses associated with direct and metabolism-dependent drug toxicity
Forootan, Shiva S, Mutter, Fiona E, Kipar, Anja, Iwawaki, Takao, Francis, Ben, Goldring, Christopher E, Park, B Kevin, Copple, Ian M
Published in Scientific reports (22.11.2017)
Published in Scientific reports (22.11.2017)
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The co-chaperone and reductase ERdj5 facilitates rod opsin biogenesis and quality control
Athanasiou, Dimitra, Bevilacqua, Dalila, Aguila, Monica, McCulley, Caroline, Kanuga, Naheed, Iwawaki, Takao, Chapple, J Paul, Cheetham, Michael E
Published in Human molecular genetics (15.12.2014)
Published in Human molecular genetics (15.12.2014)
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Correlation Between Attenuation of Protein Disulfide Isomerase Activity Through S-Mercuration and Neurotoxicity Induced by Methylmercury
Makino, Kento, Okuda, Kosaku, Sugino, Eisuke, Nishiya, Tadashi, Toyama, Takashi, Iwawaki, Takao, Fujimura, Masatake, Kumagai, Yoshito, Uehara, Takashi
Published in Neurotoxicity research (01.02.2015)
Published in Neurotoxicity research (01.02.2015)
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Direct Association of Unfolded Proteins with Mammalian ER Stress Sensor, IRE1[beta]
Oikawa, Daisuke, Kitamura, Akira, Kinjo, Masataka, Iwawaki, Takao
Published in PloS one (07.12.2012)
Published in PloS one (07.12.2012)
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Botulinum toxin B suppresses oxidative stress and the formation of decubitus-like ulcer in cutaneous ischemia–reperfusion injury mouse model
Sekiguchi, Akiko, Uchiyama, Akihiko, Fujiwara, Chisako, Ogino, Sachiko, Yokoyama, Yoko, Akai, Ryoko, Iwawaki, Takao, Ishikawa, Osamu, Motegi, Sei-ichiro
Published in Journal of dermatological science (01.05.2017)
Published in Journal of dermatological science (01.05.2017)
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IRE1α governs cytoskeleton remodelling and cell migrationthrough a direct interaction with filamin A
Urra Hery, Henriquez, Daniel R, Cánovas José, Villarroel-Campos, David, Carreras-Sureda Amado, Pulgar Eduardo, Molina, Emiliano, Hazari, Younis M, Limia, Celia M, Alvarez-Rojas, Sebastián, Figueroa, Ricardo, Vidal, Rene L, Rodriguez, Diego A, Rivera, Claudia A, Court, Felipe A, Couve Andrés, Ling, Qi, Chevet, Eric, Akai Ryoko, Iwawaki Takao, Concha, Miguel L, Glavic Álvaro, Gonzalez-Billault, Christian, Hetz Claudio
Published in Nature cell biology (01.08.2018)
Published in Nature cell biology (01.08.2018)
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Regulated Inositol-Requiring Enzyme 1 dependent mRNA decay sets the threshold for dendritic cell survival
Tavernier, Simon J., Osorio, Fabiola, Vandersarren, Lana, Vetters, Jessica, Vanlangenakker, Nele, Van Isterdael, Gert, Vergote, Karl, Parthoens, Eef, van de Laar, Lianne, Iwawaki, Takao, Del Valle, Juan R., Hu, Andrew, Lambrecht, Bart N., Janssens, Sophie
Published in Nature cell biology (01.05.2017)
Published in Nature cell biology (01.05.2017)
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Corrigendum to “Site-specific cleavage of CD59 mRNA by endoplasmic reticulum-localized ribonuclease, IRE1” [Biochem. Biophys. Res. Commun. 360 (2007) 122–127]
Oikawa, Daisuke, Tokuda, Mio, Iwawaki, Takao
Published in Biochemical and biophysical research communications (07.05.2010)
Published in Biochemical and biophysical research communications (07.05.2010)
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Mechanisms of liver injury in high fat sugar diet fed mice that lack hepatocyte X-box binding protein 1
Xiaoying Liu, Sarah A Taylor, Kyle D Gromer, Danny Zhang, Susan C Hubchak, Brian E LeCuyer, Takao Iwawaki, Zengdun Shi, Don C Rockey, Richard M Green
Published in PloS one (01.01.2022)
Published in PloS one (01.01.2022)
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Role of IRE1α in podocyte proteostasis and mitochondrial health
Navarro-Betancourt, José R, Papillon, Joan, Guillemette, Julie, Iwawaki, Takao, Chung, Chen-Fang, Cybulsky, Andrey V
Published in Cell death discovery (19.11.2020)
Published in Cell death discovery (19.11.2020)
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