Broad spectrum and potent antitumor activities of YM155, a novel small‐molecule survivin suppressant, in a wide variety of human cancer cell lines and xenograft models
Nakahara, Takahito, Kita, Aya, Yamanaka, Kentaro, Mori, Masamichi, Amino, Nobuaki, Takeuchi, Masahiro, Tominaga, Fumiko, Kinoyama, Isao, Matsuhisa, Akira, Kudou, Masafumi, Sasamata, Masao
Published in Cancer science (01.03.2011)
Published in Cancer science (01.03.2011)
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YM155, a novel small-molecule survivin suppressant, induces regression of established human hormone-refractory prostate tumor xenografts
NAKAHARA, Takahito, TAKEUCHI, Masahiro, SASAMATA, Masao, KINOYAMA, Isao, MINEMATSU, Tsuyoshi, SHIRASUNA, Kenna, MATSUHISA, Akira, KITA, Aya, TOMINAGA, Fumiko, YAMANAKA, Kentaro, KUDOH, Masafumi
Published in Cancer research (Chicago, Ill.) (01.09.2007)
Published in Cancer research (Chicago, Ill.) (01.09.2007)
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Radiosensitizing Effect of YM155, a Novel Small-Molecule Survivin Suppressant, in Non–Small Cell Lung Cancer Cell Lines
IWASA, Tsutomu, OKAMOTO, Isamu, SUZUKI, Minoru, NAKAHARA, Takahito, YAMANAKA, Kentaro, HATASHITA, Erina, YAMADA, Yuki, FUKUOKA, Masahiro, ONO, Koji, NAKAGAWA, Kazuhiko
Published in Clinical cancer research (15.10.2008)
Published in Clinical cancer research (15.10.2008)
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Journal Article
Interleukin Enhancer-binding Factor 3/NF110 Is a Target of YM155, a Suppressant of Survivin
Nakamura, Naoto, Yamauchi, Tomohiro, Hiramoto, Masashi, Yuri, Masatoshi, Naito, Masanori, Takeuchi, Masahiro, Yamanaka, Kentaro, Kita, Aya, Nakahara, Takahito, Kinoyama, Isao, Matsuhisa, Akira, Kaneko, Naoki, Koutoku, Hiroshi, Sasamata, Masao, Yokota, Hiroyuki, Kawabata, Shigeki, Furuichi, Kiyoshi
Published in Molecular & cellular proteomics (01.07.2012)
Published in Molecular & cellular proteomics (01.07.2012)
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Carrier-Mediated Uptake of 1-(2-Methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho[2,3-d]imidazolium Bromide (YM155 Monobromide), a Novel Small-Molecule Survivin Suppressant, into Human Solid Tumor and Lymphoma Cells
MINEMATSU, Tsuyoshi, IWAI, Megumi, SUGIMOTO, Kenji, SHIRAI, Nobuaki, NAKAHARA, Takahito, USUI, Takashi, KAMIMURA, Hidetaka
Published in Drug metabolism and disposition (01.03.2009)
Published in Drug metabolism and disposition (01.03.2009)
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Radiosynthesis, biodistribution and imaging of [11 C]YM155, a novel survivin suppressant, in a human prostate tumor-xenograft mouse model
Murakami, Yoshihiro, Matsuya, Takahiro, Kita, Aya, Yamanaka, Kentaro, Noda, Akihiro, Mitsuoka, Keisuke, Nakahara, Takahito, Miyoshi, Sosuke, Nishimura, Shintaro
Published in Nuclear medicine and biology (01.02.2013)
Published in Nuclear medicine and biology (01.02.2013)
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Sepantronium Bromide (YM155) induces disruption of the ILF3/p54nrb complex, which is required for survivin expression
Yamauchi, Tomohiro, Nakamura, Naoto, Hiramoto, Masashi, Yuri, Masatoshi, Yokota, Hiroyuki, Naitou, Masanori, Takeuchi, Masahiro, Yamanaka, Kentaro, Kita, Aya, Nakahara, Takahito, Kinoyama, Isao, Matsuhisa, Akira, Kaneko, Naoki, Koutoku, Hiroshi, Sasamata, Masao, Kobori, Masato, Katou, Masao, Tawara, Shuichi, Kawabata, Shigeki, Furuichi, Kiyoshi
Published in Biochemical and biophysical research communications (01.09.2012)
Published in Biochemical and biophysical research communications (01.09.2012)
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Journal Article
Sepantronium Bromide (YM155) Enhances Response of Human B-Cell Non-Hodgkin Lymphoma to Rituximab
Kita, Aya, Mitsuoka, Keisuke, Kaneko, Naoki, Nakata, Mari, Yamanaka, Kentaro, Jitsuoka, Makoto, Miyoshi, Sosuke, Noda, Akihiro, Mori, Masamichi, Nakahara, Takahito, Sasamata, Masao
Published in The Journal of pharmacology and experimental therapeutics (01.10.2012)
Published in The Journal of pharmacology and experimental therapeutics (01.10.2012)
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Antitumor Activity of YM155, a Selective Small-Molecule Survivin Suppressant, Alone and in Combination with Docetaxel in Human Malignant Melanoma Models
YAMANAKA, Kentaro, NAKAHARA, Takahito, YAMAUCHI, Tomohiro, KITA, Aya, TAKEUCHI, Masahiro, KIYONAGA, Fumiko, KANEKO, Naoki, SASAMATA, Masao
Published in Clinical cancer research (15.08.2011)
Published in Clinical cancer research (15.08.2011)
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S2G-18-2 YM155： a small molecule survivin suppressant with potent antitumor effect in human cancer xenograft models
Aya Kita, Takahito Nakahara, Masahiro Takeuchi, Isao Kinoyama, Akira Matsuhisa, Kentaro Yamanaka, Mari Nakata, Naoki Kaneko, Hiroshi Koutoku, Masao Sasamata
Published in Journal of Pharmacological Sciences (2010)
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Published in Journal of Pharmacological Sciences (2010)
Journal Article
YM155, a selective survivin suppressant, inhibits tumor spread and prolongs survival in a spontaneous metastatic model of human triple negative breast cancer
YAMANAKA, Kentaro, NAKATA, Mari, KANEKO, Naoki, FUSHIKI, Hiroshi, KITA, Aya, NAKAHARA, Takahito, KOUTOKU, Hiroshi, SASAMATA, Masao
Published in International journal of oncology (01.09.2011)
Published in International journal of oncology (01.09.2011)
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Journal Article
Sepantronium bromide (YM155) induces disruption of the ILF3/p54(nrb) complex, which is required for survivin expression
Yamauchi, Tomohiro, Nakamura, Naoto, Hiramoto, Masashi, Yuri, Masatoshi, Yokota, Hiroyuki, Naitou, Masanori, Takeuchi, Masahiro, Yamanaka, Kentaro, Kita, Aya, Nakahara, Takahito, Kinoyama, Isao, Matsuhisa, Akira, Kaneko, Naoki, Koutoku, Hiroshi, Sasamata, Masao, Kobori, Masato, Katou, Masao, Tawara, Shuichi, Kawabata, Shigeki, Furuichi, Kiyoshi
Published in Biochemical and biophysical research communications (07.09.2012)
Published in Biochemical and biophysical research communications (07.09.2012)
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Antitumor effects of YM155, a novel survivin suppressant, against human aggressive non-Hodgkin lymphoma
Kita, Aya, Nakahara, Takahito, Yamanaka, Kentaro, Nakano, Kenji, Nakata, Mari, Mori, Masamichi, Kaneko, Naoki, Koutoku, Hiroshi, Izumisawa, Nobuyuki, Sasamata, Masao
Published in Leukemia research (01.06.2011)
Published in Leukemia research (01.06.2011)
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YM155, a novel survivin suppressant, enhances taxane-induced apoptosis and tumor regression in a human Calu 6 lung cancer xenograft model
Nakahara, Takahito, Yamanaka, Kentaro, Hatakeyama, Shinji, Kita, Aya, Takeuchi, Masahiro, Kinoyama, Isao, Matsuhisa, Akira, Nakano, Kenji, Shishido, Takao, Koutoku, Hiroshi, Sasamata, Masao
Published in Anti-cancer drugs (01.06.2011)
Published in Anti-cancer drugs (01.06.2011)
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Sepantronium bromide (YM155) enhances response of human B-cell non-Hodgkin lymphoma to rituximab
Kita, Aya, Mitsuoka, Keisuke, Kaneko, Naoki, Nakata, Mari, Yamanaka, Kentaro, Jitsuoka, Makoto, Miyoshi, Sosuke, Noda, Akihiro, Mori, Masamichi, Nakahara, Takahito, Sasamata, Masao
Published in The Journal of pharmacology and experimental therapeutics (01.10.2012)
Published in The Journal of pharmacology and experimental therapeutics (01.10.2012)
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Journal Article
Suppression of survivin promoter activity by YM155 involves disruption of Sp1-DNA interaction in the survivin core promoter
Cheng, Qiuying, Ling, Xiang, Haller, Andrew, Nakahara, Takahito, Yamanaka, Kentaro, Kita, Aya, Koutoku, Hiroshi, Takeuchi, Masahiro, Brattain, Michael G, Li, Fengzhi
Published in International journal of biochemistry and molecular biology (2012)
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Published in International journal of biochemistry and molecular biology (2012)
Journal Article
Abstract 4756: YM155 suppresses survivin expression by disrupting the ILF3/p54nrb transcription factor complex
Nakamura, Naoto, Yamauchi, Tomohiro, Hiramoto, Masashi, Yuri, Masatoshi, Naito, Masanori, Takeuchi, Masahiro, Yamanaka, Kentaro, Nakahara, Takahito, Kita, Aya, Kinoyama, Isao, Matsuhisa, Akira, Sasamata, Masao, Yokota, Hiroyuki, Kawabata, Shigeki, Furuichi, Kiyoshi
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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