NUDT15 codon 139 is the best pharmacogenetic marker for predicting thiopurine-induced severe adverse events in Japanese patients with inflammatory bowel disease: a multicenter study
Kakuta, Yoichi, Kawai, Yosuke, Okamoto, Daisuke, Takagawa, Tetsuya, Ikeya, Kentaro, Sakuraba, Hirotake, Nishida, Atsushi, Nakagawa, Shoko, Miura, Miki, Toyonaga, Takahiko, Onodera, Kei, Shinozaki, Masaru, Ishiguro, Yoh, Mizuno, Shinta, Takahara, Masahiro, Yanai, Shunichi, Hokari, Ryota, Nakagawa, Tomoo, Araki, Hiroshi, Motoya, Satoshi, Naito, Takeo, Moroi, Rintaro, Shiga, Hisashi, Endo, Katsuya, Kobayashi, Taku, Naganuma, Makoto, Hiraoka, Sakiko, Matsumoto, Takayuki, Nakamura, Shiro, Nakase, Hiroshi, Hisamatsu, Tadakazu, Sasaki, Makoto, Hanai, Hiroyuki, Andoh, Akira, Nagasaki, Masao, Kinouchi, Yoshitaka, Shimosegawa, Tooru, Masamune, Atsushi, Suzuki, Yasuo
Published in Journal of gastroenterology (01.09.2018)
Published in Journal of gastroenterology (01.09.2018)
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Increased DNA-incorporated thiopurine metabolite as a possible mechanism for leukocytopenia through cell apoptosis in inflammatory bowel disease patients with NUDT15 mutation
Toyonaga, Takahiko, Kobayashi, Taku, Kuronuma, Satoshi, Ueno, Aito, Kiyohara, Hiroki, Okabayashi, Shinji, Takeuchi, Osamu, Redfern, Christopher P. F., Terai, Hideki, Ozaki, Ryo, Sagami, Shintaro, Nakano, Masaru, Coulthard, Sally A., Tanaka, Yoichi, Hibi, Toshifumi
Published in Journal of gastroenterology (01.11.2021)
Published in Journal of gastroenterology (01.11.2021)
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Increased colonic expression of ACE2 associates with poor prognosis in Crohn’s disease
Toyonaga, Takahiko, Araba, Kenza C., Kennedy, Meaghan M., Keith, Benjamin P., Wolber, Elisabeth A., Beasley, Caroline, Steinbach, Erin C., Schaner, Matthew R., Jain, Animesh, Long, Millie D., Barnes, Edward L., Herfarth, Hans H., Isaacs, Kim L., Hansen, Jonathan J., Kapadia, Muneera R., Guillem, José Gaston, Gulati, Ajay S., Sethupathy, Praveen, Furey, Terrence S., Ehre, Camille, Sheikh, Shehzad Z.
Published in Scientific reports (29.06.2021)
Published in Scientific reports (29.06.2021)
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Combination of colonoscopy and magnetic resonance enterography is more useful for clinical decision making than colonoscopy alone in patients with complicated Crohn's disease
Sagami, Shintaro, Kobayashi, Taku, Kikkawa, Nao, Umeda, Satoko, Nakano, Masaru, Toyonaga, Takahiko, Okabayashi, Shinji, Ozaki, Ryo, Hibi, Toshifumi
Published in PloS one (20.02.2019)
Published in PloS one (20.02.2019)
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Usefulness of fecal calprotectin for the early prediction of short-term outcomes of remission-induction treatments in ulcerative colitis in comparison with two-item patient-reported outcome
Toyonaga, Takahiko, Kobayashi, Taku, Nakano, Masaru, Saito, Eiko, Umeda, Satoko, Okabayashi, Shinji, Ozaki, Ryo, Hibi, Toshifumi
Published in PloS one (21.09.2017)
Published in PloS one (21.09.2017)
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Lipocalin 2 prevents intestinal inflammation by enhancing phagocytic bacterial clearance in macrophages
Toyonaga, Takahiko, Matsuura, Minoru, Mori, Kiyoshi, Honzawa, Yusuke, Minami, Naoki, Yamada, Satoshi, Kobayashi, Taku, Hibi, Toshifumi, Nakase, Hiroshi
Published in Scientific reports (13.10.2016)
Published in Scientific reports (13.10.2016)
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Osteopontin attenuates acute gastrointestinal graft-versus-host disease by preventing apoptosis of intestinal epithelial cells
Kawakami, Kentaro, Minami, Naoki, Matsuura, Minoru, Iida, Tomoya, Toyonaga, Takahiko, Nagaishi, Kanna, Arimura, Yoshiaki, Fujimiya, Mineko, Uede, Toshimitsu, Nakase, Hiroshi
Published in Biochemical and biophysical research communications (01.04.2017)
Published in Biochemical and biophysical research communications (01.04.2017)
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Osteopontin Deficiency Accelerates Spontaneous Colitis in Mice with Disrupted Gut Microbiota and Macrophage Phagocytic Activity
Toyonaga, Takahiko, Nakase, Hiroshi, Ueno, Satoru, Matsuura, Minoru, Yoshino, Takuya, Honzawa, Yusuke, Itou, Ayako, Namba, Kazuyoshi, Minami, Naoki, Yamada, Satoshi, Koshikawa, Yorimitsu, Uede, Toshimitsu, Chiba, Tsutomu, Okazaki, Kazuichi
Published in PloS one (14.08.2015)
Published in PloS one (14.08.2015)
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Long-term efficacy of infliximab for refractory ulcerative colitis: results from a single center experience
Yamada, Satoshi, Yoshino, Takuya, Matsuura, Minoru, Minami, Naoki, Toyonaga, Takahiko, Honzawa, Yusuke, Tsuji, Yoshihisa, Nakase, Hiroshi
Published in BMC gastroenterology (23.04.2014)
Published in BMC gastroenterology (23.04.2014)
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Diagnosis and treatment of ulcerative colitis with cytomegalovirus infection: importance of controlling mucosal inflammation to prevent cytomegalovirus reactivation
Nakase, Hiroshi, Honzawa, Yusuke, Toyonaga, Takahiko, Yamada, Satoshi, Minami, Naoki, Yoshino, Takuya, Matsuura, Minoru
Published in Intestinal research (01.01.2014)
Published in Intestinal research (01.01.2014)
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Prior use of immunomodulatory drugs improves the clinical outcome of endoscopic balloon dilation for intestinal stricture in patients with Crohn's disease
Honzawa, Yusuke, Nakase, Hiroshi, Matsuura, Minoru, Higuchi, Hirokazu, Toyonaga, Takahiko, Matsumura, Kayoko, Yoshino, Takuya, Okazaki, Kazuichi, Chiba, Tsutomu
Published in Digestive endoscopy (01.09.2013)
Published in Digestive endoscopy (01.09.2013)
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Randomized, crossover questionnaire survey of acceptabilities of controlled-release mesalazine tablets and granules in ulcerative colitis patients
Yagisawa, Keiji, Kobayashi, Taku, Ozaki, Ryo, Okabayashi, Shinji, Toyonaga, Takahiko, Miura, Miki, Hayashida, Mari, Saito, Eiko, Nakano, Masaru, Matsubara, Hajime, Hisamatsu, Tadakazu, Hibi, Toshifumi
Published in Intestinal research (01.01.2019)
Published in Intestinal research (01.01.2019)
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Corrigendum: Randomized, crossover questionnaire survey of acceptabilities of controlled-release mesalazine tablets and granules in ulcerative colitis patients
Yagisawa, Keiji, Kobayashi, Taku, Ozaki, Ryo, Okabayashi, Shinji, Toyonaga, Takahiko, Miura, Miki, Hayashida, Mari, Saito, Eiko, Nakano, Masaru, Matsubara, Hajime, Hisamatsu, Tadakazu, Hibi, Toshifumi
Published in Intestinal research (01.07.2020)
Published in Intestinal research (01.07.2020)
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Individualized treatment based on CYP3A5 single-nucleotide polymorphisms with tacrolimus in ulcerative colitis
Okabayashi, Shinji, Kobayashi, Taku, Saito, Eiko, Toyonaga, Takahiko, Ozaki, Ryo, Sagami, Shintaro, Nakano, Masaru, Tanaka, Junichi, Yagisawa, Keiji, Kuronuma, Satoshi, Takeuchi, Osamu, Hibi, Toshifumi
Published in Intestinal research (01.04.2019)
Published in Intestinal research (01.04.2019)
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Efficacy and Safety of Long-Term Thiopurine Maintenance Treatment in Japanese Patients With Ulcerative Colitis
Yamada, Satoshi, Yoshino, Takuya, Matsuura, Minoru, Kimura, Masamichi, Koshikawa, Yorimitsu, Minami, Naoki, Toyonaga, Takahiko, Honzawa, Yusuke, Nakase, Hiroshi
Published in Intestinal research (01.07.2015)
Published in Intestinal research (01.07.2015)
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Steroid-refractory extensive enteritis complicated by ulcerative colitis successfully treated with adalimumab
Okabayashi, Shinji, Kobayashi, Taku, Sujino, Tomohisa, Ozaki, Ryo, Umeda, Satoko, Toyonaga, Takahiko, Saito, Eiko, Nakano, Masaru, Tablante, Maria Carla, Morinaga, Shojiroh, Hibi, Toshifumi
Published in Intestinal Research (01.10.2017)
Published in Intestinal Research (01.10.2017)
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Corrigendum: Randomized, crossover questionnaire survey of acceptabilities of controlled-release mesalazine tablets and granules in ulcerative colitis patients
Keiji Yagisawa, Taku Kobayashi, Ryo Ozaki, Shinji Okabayashi, Takahiko Toyonaga, Miki Miura, Mari Hayashida, Eiko Saito, Masaru Nakano, Hajime Matsubara, Tadakazu Hisamatsu, Toshifumi Hibi
Published in Intestinal research (Intest Res) (30.07.2020)
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Published in Intestinal research (Intest Res) (30.07.2020)
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Efficacy of Thiopurines in Biologic-Naive Japanese Patients With Crohn's Disease: A Single-Center Experience
Yoshino, Takuya, Matsuura, Minoru, Minami, Naoki, Yamada, Satoshi, Honzawa, Yusuke, Kimura, Masamichi, Koshikawa, Yorimitsu, Madian, Ali, Toyonaga, Takahiko, Nakase, Hiroshi
Published in Intestinal research (01.07.2015)
Published in Intestinal research (01.07.2015)
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