Chronic cerebral hypoperfusion induced by right unilateral common carotid artery occlusion causes delayed white matter lesions and cognitive impairment in adult mice
Yoshizaki, Kaichi, Adachi, Kayo, Kataoka, Seiko, Watanabe, Atsushi, Tabira, Takeshi, Takahashi, Keikichi, Wakita, Hideaki
Published in Experimental neurology (01.04.2008)
Published in Experimental neurology (01.04.2008)
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Mutations in NOTCH3 cause the formation and retention of aggregates in the endoplasmic reticulum, leading to impaired cell proliferation
Takahashi, Keikichi, Adachi, Kayo, Yoshizaki, Kaichi, Kunimoto, Shohko, Kalaria, Raj N., Watanabe, Atsushi
Published in Human molecular genetics (01.01.2010)
Published in Human molecular genetics (01.01.2010)
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Functional redundancy of the Notch gene family during mouse embryogenesis: Analysis of Notch gene expression in Notch3-deficient mice
Kitamoto, Takeo, Takahashi, Keikichi, Takimoto, Hiroaki, Tomizuka, Kazuma, Hayasaka, Michiko, Tabira, Takeshi, Hanaoka, Kazunori
Published in Biochemical and biophysical research communications (17.06.2005)
Published in Biochemical and biophysical research communications (17.06.2005)
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Conditional expression of microRNA against E-selectin inhibits leukocyte–endothelial adhesive interaction under inflammatory condition
Yoshizaki, Kaichi, Wakita, Hideaki, Takeda, Kazuya, Takahashi, Keikichi
Published in Biochemical and biophysical research communications (11.07.2008)
Published in Biochemical and biophysical research communications (11.07.2008)
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Genetic, clinical and pathological studies of CADASIL in Japan: a partial contribution of Notch3 mutations and implications of smooth muscle cell degeneration for the pathogenesis
Santa, Yo, Uyama, Eiichiro, Chui, De Hua, Arima, Masakuni, Kotorii, Satoshi, Takahashi, Keikichi, Tabira, Takeshi
Published in Journal of the neurological sciences (15.08.2003)
Published in Journal of the neurological sciences (15.08.2003)
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Mutational Analysis of Intrinsic Regions of Presenilin 2 That Determine Its Endoproteolytic Cleavage and Pathological Function
Shirotani, Keiro, Takahashi, Keikichi, Araki, Wataru, Maruyama, Kei, Tabira, Takeshi
Published in The Journal of biological chemistry (04.02.2000)
Published in The Journal of biological chemistry (04.02.2000)
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Serial analysis of gene expression in a microglial cell line
Inoue, Haruhisa, Sawada, Makoto, Ryo, Akihide, Tanahashi, Hiroshi, Wakatsuki, Toru, Hada, Akiyuki, Kondoh, Nobuo, Nakagaki, Keiko, Takahashi, Keikichi, Suzumura, Akio, Yamamoto, Mikio, Tabira, Takeshi
Published in Glia (01.12.1999)
Published in Glia (01.12.1999)
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Determination of a Cleavage Site of Presenilin 2 Protein in Stably Transfected SH-SY5Y Human Neuroblastoma Cell Lines
Shirotani, Keiro, Takahashi, Keikichi, Ozawa, Kazuharu, Kunishita, Tatsuhide, Tabira, Takeshi
Published in Biochemical and biophysical research communications (26.11.1997)
Published in Biochemical and biophysical research communications (26.11.1997)
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Arg133Cys mutation of Notch3 in two unrelated Japanese families with CADASIL
UYAMA, Eiichiro, TOKUNAGA, Makoto, SUENAGA, Akihito, KOTORII, Satoru, KAMIMURA, Kohei, TAKAHASHI, Keikichi, TABIRA, Takeshi, UCHINO, Makoto
Published in Internal medicine (Tokyo, 1992) (01.09.2000)
Published in Internal medicine (Tokyo, 1992) (01.09.2000)
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TCR repertoire to proteolipid protein (PLP) in multiple sclerosis (MS): homologies between PLP-specific T cells and MS-associated T cells in TCR junctional sequences
Kondo, Takayuki, Yamamura, Takashi, Inobe, Jun-ichi, Ohashi, Takashi, Takahashi, Keikichi, Tabira, Takeshi
Published in International immunology (01.01.1996)
Published in International immunology (01.01.1996)
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A case of early stage CADASIL showing only dizziness and vertigo with a novel mutation of Notch 3 gene
Matsumoto, Hideyuki, Tsumoto, Manabu, Yamamoto, Tomotaka, Takahashi, Keikichi, Tahira, Takeshi, Ugawa, Yoshikazu, Tsuji, Shoji
Published in Rinshō shinkeigaku (01.01.2005)
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Published in Rinshō shinkeigaku (01.01.2005)
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Potent inhibitors of amyloid β fibrillization, 4,5-dianilinophthalimide and staurosporine aglycone, enhance degradation of preformed aggregates of mutant Notch3
Takahashi, Keikichi, Adachi, Kayo, Kunimoto, Shohko, Wakita, Hideaki, Takeda, Kazuya, Watanabe, Atsushi
Published in Biochemical and biophysical research communications (05.11.2010)
Published in Biochemical and biophysical research communications (05.11.2010)
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Transgenic mice with Alzheimer presenilin 1 mutations show accelerated neurodegeneration without amyloid plaque formation
Tabira, Takeshi, Chui, De-Hua, Tanahashi, Hiroshi, Ozawa, Kazuharu, Ikeda, Sachiya, Checler, Frédéric, Ueda, Otoya, Suzuki, Hiroshi, Araki, Wataru, Inoue, Haruhisa, Shirotani, Keiro, Takahashi, Keikichi, Gallyas, Ferenc
Published in Nature medicine (01.05.1999)
Published in Nature medicine (01.05.1999)
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Potent inhibitors of amyloid b fibrillization, 4,5-dianilinophthalimide and staurosporine aglycone, enhance degradation of preformed aggregates of mutant Notch3
Takahashi, Keikichi, Adachi, Kayo, Kunimoto, Shohko, Wakita, Hideaki, Takeda, Kazuya, Watanabe, Atsushi
Published in Biochemical and biophysical research communications (05.11.2010)
Published in Biochemical and biophysical research communications (05.11.2010)
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Development of a safe oral Aβ vaccine using recombinant adeno-associated virus vector for Alzheimer's disease
Hara, Hideo, Monsonego, Alon, Yuasa, Katsutoshi, Adachi, Kayo, Xiao, Xiao, Takeda, Shin'ichi, Takahashi, Keikichi, Weiner, Howard L., Tabira, Takeshi
Published in Journal of Alzheimer's disease (01.10.2004)
Published in Journal of Alzheimer's disease (01.10.2004)
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Development of mouse model for CADASIL using mutated Notch3 gene-chronic stress interaction
Kunimoto, Shohko, Takahashi, Keikichi, Adachi, Kayo, Matsuzaki, Mikiko, Takeda, Kazuya, Wakita, Hideaki, Kalaria, Rajesh N., Maruyama, Wakako, Watanabe, Atsushi
Published in Neuroscience research (01.09.2011)
Published in Neuroscience research (01.09.2011)
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