Activation of phosphatidylinositol 3-kinase/Akt signaling pathway mediates acquired resistance to sorafenib in hepatocellular carcinoma cells
Chen, Kuen-Feng, Chen, Hui-Ling, Tai, Wei-Tien, Feng, Wen-Chi, Hsu, Chih-Hung, Chen, Pei-Jer, Cheng, Ann-Lii
Published in The Journal of pharmacology and experimental therapeutics (01.04.2011)
Published in The Journal of pharmacology and experimental therapeutics (01.04.2011)
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Journal Article
Nilotinib Induces Autophagy in Hepatocellular Carcinoma through AMPK Activation
Yu, Hui-Chuan, Lin, Chen-Si, Tai, Wei-Tien, Liu, Chun-Yu, Shiau, Chung-Wai, Chen, Kuen-Feng
Published in The Journal of biological chemistry (21.06.2013)
Published in The Journal of biological chemistry (21.06.2013)
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Journal Article
Signal transducer and activator of transcription 3 is a major kinase-independent target of sorafenib in hepatocellular carcinoma
Tai, Wei-Tien, Cheng, Ann-Lii, Shiau, Chung-Wai, Huang, Hsiang-Po, Huang, Jui-Wen, Chen, Pei-Jer, Chen, Kuen-Feng
Published in Journal of hepatology (01.11.2011)
Published in Journal of hepatology (01.11.2011)
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Journal Article
Protein tyrosine phosphatase 1B dephosphorylates PITX1 and regulates p120RasGAP in hepatocellular carcinoma
Tai, Wei‐Tien, Chen, Yao‐Li, Chu, Pei‐Yi, Chen, Li‐Ju, Hung, Man‐Hsin, Shiau, Chung‐Wai, Huang, Jui‐Wen, Tsai, Ming‐Hsien, Chen, Kuen‐Feng
Published in Hepatology (Baltimore, Md.) (01.05.2016)
Published in Hepatology (Baltimore, Md.) (01.05.2016)
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Journal Article
STAT3 mediates regorafenib-induced apoptosis in hepatocellular carcinoma
Tai, Wei-Tien, Chu, Pei-Yi, Shiau, Chung-Wai, Chen, Yao-Li, Li, Yong-Shi, Hung, Man-Hsin, Chen, Li-Ju, Chen, Pei-Lung, Su, Jung-Chen, Lin, Ping-Yi, Yu, Hui-Chuan, Chen, Kuen-Feng
Published in Clinical cancer research (15.11.2014)
Published in Clinical cancer research (15.11.2014)
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Journal Article
Sorafenib Overcomes TRAIL Resistance of Hepatocellular Carcinoma Cells through the Inhibition of STAT3
CHEN, Kuen-Feng, TAI, Wei-Tien, LIU, Tsung-Hao, HUANG, Hsiang-Po, LIN, Yu-Chin, SHIAU, Chung-Wai, LI, Pui-Kai, CHEN, Pei-Jer, CHENG, Ann-Lii
Published in Clinical cancer research (01.11.2010)
Published in Clinical cancer research (01.11.2010)
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Journal Article
Dovitinib induces apoptosis and overcomes sorafenib resistance in hepatocellular carcinoma through SHP-1-mediated inhibition of STAT3
Tai, Wei-Tien, Cheng, Ann-Lii, Shiau, Chung-Wai, Liu, Chun-Yu, Ko, Ching-Huai, Lin, Mai-Wei, Chen, Pei-Jer, Chen, Kuen-Feng
Published in Molecular cancer therapeutics (01.02.2012)
Published in Molecular cancer therapeutics (01.02.2012)
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Journal Article
Discovery of novel src homology region 2 domain‐containing phosphatase 1 agonists from sorafenib for the treatment of hepatocellular carcinoma
Tai, Wei‐Tien, Shiau, Chung‐Wai, Chen, Pei‐Jer, Chu, Pei‐Yi, Huang, Hsiang‐Po, Liu, Chun‐Yu, Huang, Jui‐Wen, Chen, Kuen‐Feng
Published in Hepatology (Baltimore, Md.) (01.01.2014)
Published in Hepatology (Baltimore, Md.) (01.01.2014)
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Journal Article
Sorafenib and its derivative SC-1 exhibit antifibrotic effects through signal transducer and activator of transcription 3 inhibition
Su, Tung-Hung, Shiau, Chung-Wai, Jao, Ping, Liu, Chen-Hua, Liu, Chun-Jen, Tai, Wei-Tien, Jeng, Yung-Ming, Yang, Hung-Chih, Tseng, Tai-Chung, Huang, Hsiang-Po, Cheng, Huei-Ru, Chen, Pei-Jer, Chen, Kuen-Feng, Kao, Jia-Horng, Chen, Ding-Shinn
Published in Proceedings of the National Academy of Sciences - PNAS (09.06.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (09.06.2015)
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Journal Article
Sorafenib Enhances Radiation-Induced Apoptosis in Hepatocellular Carcinoma by Inhibiting STAT3
Huang, Chao-Yuan, MD, PhD, Lin, Chen-Si, PhD, Tai, Wei-Tien, PhD, Hsieh, Chi-Ying, MS, Shiau, Chung-Wai, PhD, Cheng, Ann-Lii, MD, PhD, Chen, Kuen-Feng, MD, PhD
Published in International journal of radiation oncology, biology, physics (01.07.2013)
Published in International journal of radiation oncology, biology, physics (01.07.2013)
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Journal Article
A combination of sorafenib and SC-43 is a synergistic SHP-1 agonist duo to advance hepatocellular carcinoma therapy
Chao, Tzu-I, Tai, Wei-Tien, Hung, Man-Hsin, Tsai, Ming-Hsien, Chen, Min-Hsuan, Chang, Mao-Ju, Shiau, Chung-Wai, Chen, Kuen-Feng
Published in Cancer letters (28.02.2016)
Published in Cancer letters (28.02.2016)
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Journal Article
Inhibition of Bcl-2 improves effect of LCL161, a SMAC mimetic, in hepatocellular carcinoma cells
Chen, Kuen-Feng, Lin, Jing-Ping, Shiau, Chung-Wai, Tai, Wei-Tien, Liu, Chun-Yu, Yu, Hui-Chuan, Chen, Pei-Jer, Cheng, Ann-Lii
Published in Biochemical pharmacology (01.08.2012)
Published in Biochemical pharmacology (01.08.2012)
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Journal Article
Pharmacological Targeting SHP-1-STAT3 Signaling Is a Promising Therapeutic Approach for the Treatment of Colorectal Cancer
Fan, Li-Ching, Teng, Hao-Wei, Shiau, Chung-Wai, Tai, Wei-Tien, Hung, Man-Hsin, Yang, Shung-Haur, Jiang, Jeng-Kai, Chen, Kuen-Feng
Published in Neoplasia (New York, N.Y.) (01.09.2015)
Published in Neoplasia (New York, N.Y.) (01.09.2015)
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Journal Article
SC-2001 Overcomes STAT3-mediated Sorafenib Resistance through RFX-1/SHP-1 Activation in Hepatocellular Carcinoma
Su, Jung-Chen, Tseng, Ping-Hui, Wu, Szu-Hsien, Hsu, Cheng-Yi, Tai, Wei-Tien, Li, Yong-Shi, Chen, I-Ting, Liu, Chun-Yu, Chen, Kuen-Feng, Shiau, Chung-Wai
Published in Neoplasia (New York, N.Y.) (01.07.2014)
Published in Neoplasia (New York, N.Y.) (01.07.2014)
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Journal Article
Src-homology protein tyrosine phosphatase-1 agonist, SC-43, reduces liver fibrosis
Su, Tung-Hung, Shiau, Chung-Wai, Jao, Ping, Yang, Nian-Jie, Tai, Wei-Tien, Liu, Chun-Jen, Tseng, Tai-Chung, Yang, Hung-Chih, Liu, Chen-Hua, Huang, Kai-Wen, Hu, Ting-Chen, Huang, Yu-Jen, Wu, Yao-Ming, Chen, Li-Ju, Chen, Pei-Jer, Chen, Ding-Shinn, Chen, Kuen-Feng, Kao, Jia-Horng
Published in Scientific reports (11.05.2017)
Published in Scientific reports (11.05.2017)
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Journal Article
SHP-1 is a target of regorafenib in colorectal cancer
Fan, Li-Ching, Teng, Hao-Wei, Shiau, Chung-Wai, Lin, Hang, Hung, Man-Hsin, Chen, Yen-Lin, Huang, Jui-Wen, Tai, Wei-Tien, Yu, Hui-Chuan, Chen, Kuen-Feng
Published in Oncotarget (15.08.2014)
Published in Oncotarget (15.08.2014)
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Journal Article
Sorafenib and its derivative SC‐49 sensitize hepatocellular carcinoma cells to CS‐1008, a humanized anti‐TNFRSF10B (DR5) antibody
Chen, Kuen‐Feng, Chen, Hui‐Ling, Shiau, Chung‐Wai, Liu, Chun‐Yu, Chu, Pei‐Yi, Tai, Wei‐Tien, Ichikawa, Kimihisa, Chen, Pei‐Jer, Cheng, Ann‐Lii
Published in British journal of pharmacology (01.02.2013)
Published in British journal of pharmacology (01.02.2013)
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Journal Article
ALK inhibitors increase ALK expression and sensitize neuroblastoma cells to ALK.CAR-T cells
Bergaggio, Elisa, Tai, Wei-Tien, Aroldi, Andrea, Mecca, Carmen, Landoni, Elisa, Nüesch, Manuel, Mota, Ines, Metovic, Jasna, Molinaro, Luca, Ma, Leyuan, Alvarado, Diego, Ambrogio, Chiara, Voena, Claudia, Blasco, Rafael B, Li, Tongqing, Klein, Daryl, Irvine, Darrell J, Papotti, Mauro, Savoldo, Barbara, Dotti, Gianpietro, Chiarle, Roberto
Published in Cancer cell (11.12.2023)
Published in Cancer cell (11.12.2023)
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