Design of N‑Benzoxaborole Benzofuran GSK8175Optimization of Human Pharmacokinetics Inspired by Metabolites of a Failed Clinical HCV Inhibitor
Chong, Pek Y, Shotwell, J. Brad, Miller, John, Price, Daniel J, Maynard, Andy, Voitenleitner, Christian, Mathis, Amanda, Williams, Shawn, Pouliot, Jeffrey J, Creech, Katrina, Wang, Feng, Fang, Jing, Zhang, Huichang, Tai, Vincent W.-F, Turner, Elizabeth, Kahler, Kirsten M, Crosby, Renae, Peat, Andrew J
Published in Journal of medicinal chemistry (11.04.2019)
Published in Journal of medicinal chemistry (11.04.2019)
Get full text
Journal Article
The ingenol-based protein kinase C agonist GSK445A is a potent inducer of HIV and SIV RNA transcription
Okoye, Afam A, Fromentin, Rémi, Takata, Hiroshi, Brehm, Jessica H, Fukazawa, Yoshinori, Randall, Bryan, Pardons, Marion, Tai, Vincent, Tang, Jun, Smedley, Jeremy, Axthelm, Michael, Lifson, Jeffrey D, Picker, Louis J, Favre, David, Trautmann, Lydie, Chomont, Nicolas
Published in PLoS pathogens (01.01.2022)
Published in PLoS pathogens (01.01.2022)
Get full text
Journal Article
Hepatitis C Replication Inhibitors That Target the Viral NS4B Protein
Miller, John F., Chong, Pek Y., Shotwell, J. Brad, Catalano, John G., Tai, Vincent W.-F., Fang, Jing, Banka, Anna L., Roberts, Christopher D., Youngman, Michael, Zhang, Huichang, Xiong, Zhiping, Mathis, Amanda, Pouliot, Jeffery J., Hamatake, Robert K., Price, Daniel J., Seal, John W., Stroup, Lisa L., Creech, Katrina L., Carballo, Luz H., Todd, Dan, Spaltenstein, Andrew, Furst, Sylvia, Hong, Zhi, Peat, Andrew J.
Published in Journal of medicinal chemistry (13.03.2014)
Published in Journal of medicinal chemistry (13.03.2014)
Get full text
Journal Article
Design and synthesis of spirocyclic compounds as HCV replication inhibitors by targeting viral NS4B protein
Tai, Vincent W.-F., Garrido, Dulce, Price, Daniel J., Maynard, Andrew, Pouliot, Jeffrey J., Xiong, Zhiping, Seal, John W., Creech, Katrina L., Kryn, Luz H., Baughman, Todd M., Peat, Andrew J.
Published in Bioorganic & medicinal chemistry letters (15.05.2014)
Published in Bioorganic & medicinal chemistry letters (15.05.2014)
Get full text
Journal Article
Handheld Optical Coherence Tomography Normative Inner Retinal Layer Measurements for Children <5 Years of Age
Lim, Maria E., Jiramongkolchai, Kim, Xu, Limin, Freedman, Sharon F., Tai, Vincent, Toth, Cynthia A., El-Dairi, Mays A.
Published in American journal of ophthalmology (01.11.2019)
Published in American journal of ophthalmology (01.11.2019)
Get full text
Journal Article
Optical Coherence Tomography Reflective Drusen Substructures Predict Progression to Geographic Atrophy in Age-related Macular Degeneration
Veerappan, Malini, BA, El-Hage-Sleiman, Abdul-Karim M., MD, Tai, Vincent, MS, Chiu, Stephanie J., PhD, Winter, Katrina P., BS, Stinnett, Sandra S., DPH, Hwang, Thomas S., MD, Hubbard, G. Baker, MD, Michelson, Michelle, BS, Gunther, Randall, MS, Wong, Wai T., MD, PhD, Chew, Emily Y., MD, Toth, Cynthia A., MD
Published in Ophthalmology (Rochester, Minn.) (01.12.2016)
Published in Ophthalmology (Rochester, Minn.) (01.12.2016)
Get full text
Journal Article
Imidazo[1,2-a]pyridines That Directly Interact with Hepatitis C NS4B: Initial Preclinical Characterization
Shotwell, J. Brad, Baskaran, Subramanian, Chong, Pek, Creech, Katrina L, Crosby, Renae M, Dickson, Hamilton, Fang, Jing, Garrido, Dulce, Mathis, Amanda, Maung, Jack, Parks, Derek J, Pouliot, Jeffrey J, Price, Daniel J, Rai, Roopa, Seal, John W, Schmitz, Uli, Tai, Vincent W. F, Thomson, Michael, Xie, Mi, Xiong, Zhiping Z, Peat, Andrew J
Published in ACS medicinal chemistry letters (12.07.2012)
Published in ACS medicinal chemistry letters (12.07.2012)
Get full text
Journal Article
Poorer Neurodevelopmental Outcomes Associated with Cystoid Macular Edema Identified in Preterm Infants in the Intensive Care Nursery
Rothman, Adam L., BS, Tran-Viet, Du, BS, Gustafson, Kathryn E., PhD, Goldstein, Ricki F., MD, Maguire, Maureen G., PhD, Tai, Vincent, MS, Sarin, Neeru, MBBS, Tong, Amy Y., MD, Huang, Jiayan, MS, Kupper, Laura, MD, Cotten, C. Michael, MD, MHS, Freedman, Sharon F., MD, Toth, Cynthia A., MD
Published in Ophthalmology (Rochester, Minn.) (01.03.2015)
Published in Ophthalmology (Rochester, Minn.) (01.03.2015)
Get full text
Journal Article
70740 Impact of fundus pigmentation on retinal layer visibility on investigational bedside optical coherence tomography in preterm infants
Seely, Kai R., McCall, Michelle, McGeehan, Brendan, Winter, Katrina, Tran-Viet, Du, Tai, Vincent, Ying, Gui-Shuang, Toth, Cynthia A.
Published in Journal of clinical and translational science (01.03.2021)
Published in Journal of clinical and translational science (01.03.2021)
Get full text
Journal Article
Machine Learning OCT Predictors of Progression from Intermediate Age-Related Macular Degeneration to Geographic Atrophy and Vision Loss
Lad, Eleonora M., Sleiman, Karim, Banks, David L., Hariharan, Sanjay, Clemons, Traci, Herrmann, Rolf, Dauletbekov, Daniyar, Giani, Andrea, Chong, Victor, Chew, Emily Y., Toth, Cynthia A., Toth, Cynthia A., Wong, Wai, Huang, Thomas, Hubbard, G. Baker, Srivastava, Sunil, McCall, Michelle, Winter, Katrina, Sarin, Neeru, Hall, Katherine, McCollum, Patti, Curtis, Linda, Schuman, Stefanie, Chiu, Stephanie J., Farsiu, Sina, Tai, Vincent, Clemons, Traci, Chew, Emily
Published in Ophthalmology science (Online) (01.06.2022)
Published in Ophthalmology science (Online) (01.06.2022)
Get full text
Journal Article
4431 Utilization of swept source optical coherence tomography to optimize characterization of cystoid macular edema in preterm infants
Seely, Kai, Mangalesh, Shwetha, Winter, Katrina, Tai, Vincent, Tran-Viet, Du, Chiu, Stephanie, Toth, Cynthia
Published in Journal of clinical and translational science (01.06.2020)
Published in Journal of clinical and translational science (01.06.2020)
Get full text
Journal Article
Distribution of OCT Features within Areas of Macular Atrophy or Scar after 2 Years of Anti-VEGF Treatment for Neovascular AMD in CATT
Toth, Cynthia A, Tai, Vincent, Pistilli, Maxwell, Chiu, Stephanie J, Winter, Katrina P, Daniel, Ebenezer, Grunwald, Juan E, Jaffe, Glenn J, Martin, Daniel F, Ying, Gui-Shuang, Farsiu, Sina, Maguire, Maureen G
Published in Ophthalmology retina (01.04.2019)
Published in Ophthalmology retina (01.04.2019)
Get more information
Journal Article
Discovery and structure–activity relationship of 2-phenyl-oxazole-4-carboxamide derivatives as potent apoptosis inducers
Tai, Vincent W.-F., Sperandio, David, Shelton, Emma J., Litvak, Joane, Pararajasingham, Keith, Cebon, Ben, Lohman, Julia, Eksterowicz, John, Kantak, Seema, Sabbatini, Peter, Brown, Cindy, Zeitz, Jennifer, Reed, Chris, Maske, Bill, Graupe, Doris, Estevez, Alberto, Oeh, Jason, Wong, Darren, Ni, Yong, Sprengeler, Paul, Yee, Robert, Magill, Catherine, Neri, Anthony, Cai, Sui Xiong, Drewe, John, Qiu, Ling, Herich, John, Tseng, Ben, Kasibhatla, Shailaja, Spencer, Jeffrey R.
Published in Bioorganic & medicinal chemistry letters (01.09.2006)
Published in Bioorganic & medicinal chemistry letters (01.09.2006)
Get full text
Journal Article
Novel, potent, selective, and orally bioavailable human βII-tryptase inhibitors
Sperandio, David, Tai, Vincent W.-F., Lohman, Julia, Hirschbein, Bernie, Mendonca, Rohan, Lee, Chang-Sun, Spencer, Jeffrey R., Janc, James, Nguyen, Margaret, Beltman, Jerlyn, Sprengeler, Paul, Scheerens, Heleen, Lin, Tong, Liu, Liang, Gadre, Ashwini, Kellogg, Alisha, Green, Michael J., McGrath, Mary E.
Published in Bioorganic & medicinal chemistry letters (01.08.2006)
Published in Bioorganic & medicinal chemistry letters (01.08.2006)
Get full text
Journal Article
Ruthenium-catalyzed cis-dihydroxylation of alkenes: Scope and limitations
Shing, TKM, Tam, EKW, Tai, VWF, Chung, IHF, Jiang, Q
Published in Chemistry : a European journal (01.01.1996)
Published in Chemistry : a European journal (01.01.1996)
Get more information
Journal Article
Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-directed Serine Protease Inhibitors
Katz, Bradley A., Elrod, Kyle, Verner, Erik, Mackman, Richard L., Luong, Christine, Shrader, William D., Sendzik, Martin, Spencer, Jeffrey R., Sprengeler, Paul A., Kolesnikov, Aleks, Tai, Vincent W.-F., Hui, Hon C., Guy Breitenbucher, J., Allen, Darin, Janc, James W.
Published in Journal of molecular biology (23.05.2003)
Published in Journal of molecular biology (23.05.2003)
Get full text
Journal Article