Physiologically‐Based Pharmacokinetic Modeling in Renal and Hepatic Impairment Populations: A Pharmaceutical Industry Perspective
Heimbach, Tycho, Chen, Yuan, Chen, Jun, Dixit, Vaishali, Parrott, Neil, Peters, Sheila Annie, Poggesi, Italo, Sharma, Pradeep, Snoeys, Jan, Shebley, Mohamad, Tai, Guoying, Tse, Susanna, Upreti, Vijay V., Wang, Ying‐Hong, Tsai, Alice, Xia, Binfeng, Zheng, Ming, Zhu, Andy Z.X., Hall, Stephen
Published in Clinical pharmacology and therapeutics (01.08.2021)
Published in Clinical pharmacology and therapeutics (01.08.2021)
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No dose adjustment of metformin or substrates of organic cation transporters (OCT)1 and OCT2 and multidrug and toxin extrusion protein (MATE)1/2K with fostemsavir coadministration based on modeling approaches
Nguyen, Dung, Miao, Xiusheng, Taskar, Kunal, Magee, Mindy, Gorycki, Pete, Moore, Katy, Tai, Guoying
Published in Pharmacology research & perspectives (01.08.2024)
Published in Pharmacology research & perspectives (01.08.2024)
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Investigation of the human metabolism and disposition of the prolyl hydrolase inhibitor daprodustat using IV microtracer with Entero‐Test bile string
Tai, Guoying, Xia, Fangming, Chen, Cathy, Pereira, Adrian, Pirhalla, Jill, Miao, Xiusheng, Young, Graeme, Beaumont, Claire, Chen, Liangfu
Published in Pharmacology research & perspectives (01.12.2023)
Published in Pharmacology research & perspectives (01.12.2023)
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A Mechanism-Based Mathematical Model of Aryl Hydrocarbon Receptor-Mediated CYP1A Induction in Rats Using β-Naphthoflavone as a Tool Compound
CHEN, Emile P, LIANGFU CHEN, YAN JI, GUOYING TAI, WEN, Yuan H, ELLENS, Harma
Published in Drug metabolism and disposition (01.12.2010)
Published in Drug metabolism and disposition (01.12.2010)
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In-vitro and in-vivo effects of the CYP2C911 polymorphism on warfarin metabolism and dose
Tai, Guoying, Farin, Frederico, Rieder, Mark J, Dreisbach, Albert W, Veenstra, David L, Verlinde, Christophe L M J, Rettie, Allan E
Published in Pharmacogenetics and genomics (01.07.2005)
Published in Pharmacogenetics and genomics (01.07.2005)
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Re-engineering of CYP2C9 to Probe Acid-Base Substrate Selectivity
GUOYING TAI, DICKMANN, Leslie J, MATOVIC, Nicholas, DEVOSS, James J, GILLAM, Elizabeth M. J, RETTIE, Allan E
Published in Drug metabolism and disposition (01.10.2008)
Published in Drug metabolism and disposition (01.10.2008)
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Comparison between physiologically based pharmacokinetic and population pharmacokinetic modelling to select paediatric doses of gepotidacin in plague
Nguyen, Dung, Shaik, Jafar Sadik, Tai, Guoying, Tiffany, Courtney, Perry, Caroline, Dumont, Etienne, Gardiner, David, Barth, Aline, Singh, Rajendra, Hossain, Mohammad
Published in British journal of clinical pharmacology (01.02.2022)
Published in British journal of clinical pharmacology (01.02.2022)
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Therapeutic Protein Drug Interactions: A White Paper From the International Consortium for Innovation and Quality in Pharmaceutical Development
Coutant, David E, Boulton, David W, Dahal, Upendra P, Deslandes, Antoine, Grimaldi, Christine, Pereira, Joao N S, Säll, Carolina, Sarvaiya, Hetal, Schiller, Hilmar, Tai, Guoying, Umehara, Kenichi, Yuan, Yang, Dallas, Shannon
Published in Clinical pharmacology and therapeutics (01.06.2023)
Published in Clinical pharmacology and therapeutics (01.06.2023)
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1315. No Dose Adjustment of Metformin with Fostemsavir Coadministration Based on Mechanistic Static and Physiologically Based Pharmacokinetic Models
Nguyen, Dung N, Miao, Xiusheng, Magee, Mindy, Tai, Guoying, Gorycki, Peter D, Moore, Katy P
Published in Open forum infectious diseases (31.12.2020)
Published in Open forum infectious diseases (31.12.2020)
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Pharmacokinetics of Gepotidacin in Renal Impairment
Hossain, Mohammad, Tiffany, Courtney, Raychaudhuri, Aparna, Nguyen, Dung, Tai, Guoying, Alcorn, Harry, Preston, Richard A., Marbury, Thomas, Dumont, Etienne
Published in Clinical pharmacology in drug development (01.07.2020)
Published in Clinical pharmacology in drug development (01.07.2020)
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CYP2C9 exon 4 mutations and warfarin dose phenotype in Asians
Rettie, Allan E, Tai, Guoying, Veenstra, David L, Farin, Fred M, Srinouanprachan, Sengkeo, Lin, Yvonne S, Thummel, Kenneth E, Hines, Ronald N
Published in Blood (01.04.2003)
Published in Blood (01.04.2003)
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CYP2C9exon 4 mutations and warfarin dose phenotype in Asians
Rettie, Allan E., Tai, Guoying, Veenstra, David L., Farin, Fred M., Srinouanprachan, Sengkeo, Lin, Yvonne S., Thummel, Kenneth E., Hines, Ronald N.
Published in Blood (01.04.2003)
Published in Blood (01.04.2003)
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Localization of the C-terminus of rat glutathione S-transferase A1-1: Crystal structure of mutants W21F and W21F/F220Y
Adman, Elinor T., Le Trong, Isolde, Stenkamp, Ronald E., Nieslanik, Brenda S., Dietze, Eric C., Tai, Guoying, Ibarra, Catherine, Atkins, William M.
Published in Proteins, structure, function, and bioinformatics (01.02.2001)
Published in Proteins, structure, function, and bioinformatics (01.02.2001)
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