The multiple myeloma microenvironment is defined by an inflammatory stromal cell landscape
de Jong, Madelon M. E., Kellermayer, Zoltán, Papazian, Natalie, Tahri, Sabrin, Hofste op Bruinink, Davine, Hoogenboezem, Remco, Sanders, Mathijs A., van de Woestijne, Pieter C., Bos, P. Koen, Khandanpour, Cyrus, Vermeulen, Jessica, Moreau, Philippe, van Duin, Mark, Broijl, Annemiek, Sonneveld, Pieter, Cupedo, Tom
Published in Nature immunology (01.06.2021)
Published in Nature immunology (01.06.2021)
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Journal Article
The microenvironment in myeloma
Lomas, Oliver C, Tahri, Sabrin, Ghobrial, Irene M
Published in Current opinion in oncology (01.03.2020)
Published in Current opinion in oncology (01.03.2020)
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Journal Article
Monoclonal Gammopathy of Undetermined Significance (MGUS)-Not So Asymptomatic after All
Lomas, Oliver C, Mouhieddine, Tarek H, Tahri, Sabrin, Ghobrial, Irene M
Published in Cancers (12.06.2020)
Published in Cancers (12.06.2020)
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Journal Article
Extreme body mass index and survival in newly diagnosed multiple myeloma patients
Shah, Urvi A., Whiting, Karissa, Devlin, Sean, Ershler, Rachel, Kanapuru, Bindu, Lee, David J., Tahri, Sabrin, Gwise, Thomas, Rustad, Even H., Mailankody, Sham, Lesokhin, Alexander M., Kazandjian, Dickran, Maura, Francesco, Auclair, Daniel, Birmann, Brenda M., Usmani, Saad Z., Gormley, Nicole, Marinac, Catherine R., Landgren, Ola
Published in Blood cancer journal (New York) (12.01.2023)
Published in Blood cancer journal (New York) (12.01.2023)
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Journal Article
Pulmonary hypertension is a mild comorbidity in end-stage cystic fibrosis patients
Belle-van Meerkerk, Gerdien, MD, Cramer, Maarten J., MD, PhD, Kwakkel-van Erp, Johanna M., MD, PhD, Nugroho, Mochamed A., MD, Tahri, Sabrin, BSc, de Valk, Harold W., MD, PhD, van de Graaf, Ed A., MD, PhD
Published in The Journal of heart and lung transplantation (01.06.2013)
Published in The Journal of heart and lung transplantation (01.06.2013)
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Journal Article
Single-cell multi-omics of human clonal hematopoiesis reveals that DNMT3A R882 mutations perturb early progenitor states through selective hypomethylation
Nam, Anna S., Dusaj, Neville, Izzo, Franco, Murali, Rekha, Myers, Robert M., Mouhieddine, Tarek H., Sotelo, Jesus, Benbarche, Salima, Waarts, Michael, Gaiti, Federico, Tahri, Sabrin, Levine, Ross, Abdel-Wahab, Omar, Godley, Lucy A., Chaligne, Ronan, Ghobrial, Irene, Landau, Dan A.
Published in Nature genetics (01.10.2022)
Published in Nature genetics (01.10.2022)
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Journal Article
Clonal hematopoiesis is associated with adverse outcomes in multiple myeloma patients undergoing transplant
Mouhieddine, Tarek H., Sperling, Adam S., Redd, Robert, Park, Jihye, Leventhal, Matthew, Gibson, Christopher J., Manier, Salomon, Nassar, Amin H., Capelletti, Marzia, Huynh, Daisy, Bustoros, Mark, Sklavenitis-Pistofidis, Romanos, Tahri, Sabrin, Hornburg, Kalvis, Dumke, Henry, Itani, Muhieddine M., Boehner, Cody J., Liu, Chia-Jen, AlDubayan, Saud H., Reardon, Brendan, Van Allen, Eliezer M., Keats, Jonathan J., Stewart, Chip, Mehr, Shaadi, Auclair, Daniel, Schlossman, Robert L., Munshi, Nikhil C., Anderson, Kenneth C., Steensma, David P., Laubach, Jacob P., Richardson, Paul G., Ritz, Jerome, Ebert, Benjamin L., Soiffer, Robert J., Trippa, Lorenzo, Getz, Gad, Neuberg, Donna S., Ghobrial, Irene M.
Published in Nature communications (12.06.2020)
Published in Nature communications (12.06.2020)
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Journal Article
Inflammasome-Primed Myeloid Cells Maintain a Pro-Tumor Microenvironment in Multiple Myeloma
de Jong, Madelon M.E., Fokkema, Cathelijne, Papazian, Natalie, Tahri, Sabrin, Kellermayer, Zoltan, Vermeulen, Michael, Duin, Mark van, van de Woestijne, Pieter, Broyl, Annemiek, Sonneveld, Pieter, Cupedo, Tom
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Journal Article
Single-Cell Transcriptomic Analysis Reveals Loss of Activated Bone Marrow NK Cells in Multiple Myeloma Patients Which Associates with Disease Progression in Mice
Tahri, Sabrin, Kellermayer, Zoltan, de Jong, Madelon M.E., Papazian, Natalie, Fokkema, Cathelijne, den Hollander, Chelsea, van de Woestijne, Pieter, Duin, Mark van, Broijl, Annemiek, Sonneveld, Pieter, Cupedo, Tom
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Journal Article
Stromal Cell-Activated Bone Marrow Neutrophils Provide BAFF in Newly Diagnosed and Treated Multiple Myeloma
de Jong, Madelon M.E., Fokkema, Cathelijne, Papazian, Natalie, van Heusden, Teddie, Vermeulen, Michael, Tahri, Sabrin, Hoogenboezem, Remco, Duin, Mark van, van de Woestijne, Pieter, Langerak, Anton, Broijl, Annemiek, Sonneveld, Pieter, Cupedo, Tom
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
Single-Cell RNA-Sequencing Identifies Immune Biomarkers of Progression in Patients with High-Risk Smoldering Multiple Myeloma Treated with Immunotherapy
Sklavenitis-Pistofidis, Romanos, Aranha, Michelle P., Haradhvala, Nicholas J., Varmeh, Shohreh, Heilpern-Mallory, Daniel, Wu, Ting, Su, Nang Kham, Lightbody, Elizabeth D., Aguet, François, Zavidij, Oksana, Tahri, Sabrin, Mouhieddine, Tarek H., Getz, Gad, Ghobrial, Irene
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
Two cases of extensive limb swelling after influenza vaccination
Cohen, Emily, Tahri, Sabrin, Lukkassen, Ingrid
Published in The Pediatric infectious disease journal (01.01.2015)
Published in The Pediatric infectious disease journal (01.01.2015)
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Journal Article
An IL-1β-driven neutrophil–stromal cell axis fosters a BAFF-rich protumor microenvironment in individuals with multiple myeloma
de Jong, Madelon M. E., Fokkema, Cathelijne, Papazian, Natalie, Czeti, Ágnes, Appelman, Marjolein K., Vermeulen, Michael, van Heusden, Teddie, Hoogenboezem, Remco M., van Beek, Gregory, Tahri, Sabrin, Sanders, Mathijs A., van de Woestijne, Pieter C., Gay, Francesca, Moreau, Philippe, Büttner-Herold, Maike, Bruns, Heiko, van Duin, Mark, Broijl, Annemiek, Sonneveld, Pieter, Cupedo, Tom
Published in Nature immunology (01.05.2024)
Published in Nature immunology (01.05.2024)
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Journal Article
Immune biomarkers of response to immunotherapy in patients with high-risk smoldering myeloma
Sklavenitis-Pistofidis, Romanos, Aranha, Michelle P., Redd, Robert A., Baginska, Joanna, Haradhvala, Nicholas J., Hallisey, Margaret, Dutta, Ankit K., Savell, Alexandra, Varmeh, Shohreh, Heilpern-Mallory, Daniel, Ujwary, Sylvia, Zavidij, Oksana, Aguet, Francois, Su, Nang K., Lightbody, Elizabeth D., Bustoros, Mark, Tahri, Sabrin, Mouhieddine, Tarek H., Wu, Ting, Flechon, Lea, Anand, Shankara, Rosenblatt, Jacalyn M., Zonder, Jeffrey, Vredenburgh, James J., Boruchov, Adam, Bhutani, Manisha, Usmani, Saad Z., Matous, Jeffrey, Yee, Andrew J., Jakubowiak, Andrzej, Laubach, Jacob, Manier, Salomon, Nadeem, Omar, Richardson, Paul, Badros, Ashraf Z., Mateos, Maria-Victoria, Trippa, Lorenzo, Getz, Gad, Ghobrial, Irene M.
Published in Cancer cell (14.11.2022)
Published in Cancer cell (14.11.2022)
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Journal Article
High Levels of Circulating Tumor Cells Are Associated with Increased Bone Marrow Proliferation in Newly Diagnosed Multiple Myeloma Patients
Fokkema, Cathelijne, de Jong, Madelon M.E., Tahri, Sabrin, Kellermayer, Zoltan, den Hollander, Chelsea, Vermeulen, Michael, Papazian, Natalie, Duin, Mark van, Wevers, Michiel J.W., Sanders, Mathijs A., van der Velden, Vincent H.J., Sonneveld, Pieter, Broyl, Annemiek, Cupedo, Tom
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Journal Article
P-388 An IL-1β driven neutrophil-stromal cell axis fosters a BAFF-rich tumor-supportive bone marrow environment in multiple myeloma patients
De Jong, Madelon, Fokkema, Cathelijne, Papazian, Natalie, Tahri, Sabrin, Sanders, Mathijs, Gay, Francesca, Moreau, Philippe, Bruns, Heiko, van Duin, Mark, Broijl, Annemiek, Sonneveld, Pieter, Cupedo, Tom
Published in Clinical lymphoma, myeloma and leukemia (01.09.2023)
Published in Clinical lymphoma, myeloma and leukemia (01.09.2023)
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Journal Article
In Vivo Modeling of Clonal Competition Using CRISPR-Based Gene Editing Reveals Novel Fitness Variables in Multiple Myeloma
Shen, Yujia, Manier, Salomon, Tahri, Sabrin, Berrios, Brianna, Zavidij, Oksana, Park, Jihye, Pistofidis, Romanos, Ghobrial, Irene M.
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
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Journal Article
Inhibition of MICA and MICB Shedding Enhances Cytokine-Induced Memory-like NK Cell-Mediated Activity Against Multiple Myeloma
Tahri, Sabrin, Kham Su, Nang, Lampe, Luisa Maria, Dong, Han, Vergara Cadavid, Juliana, Papazian, Natalie, Cao, Amanda, Alberge, Jean-Baptiste, Ferrari de Andrade, Lucas, Rahmat, Mahshid, Shen, Yujia, Boiarsky, Rebecca, Blanco, Laura, Paiva, Bruno, Guenther, Andreas, Getz, Gad, Sonneveld, Pieter, Cupedo, Tom, Wucherpfennig, Kai W., Ghobrial, Irene, Romee, Rizwan
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
Single-Cell Transcriptomic Analysis Reveals Reduction of Cytotoxic NK Cells in a Subset of Newly Diagnosed Multiple Myeloma Patients Impacting Outcome after Daratumumab Therapy
Tahri, Sabrin, de Jong, Madelon M.E., Fokkema, Cathelijne, Papazian, Natalie, Kellermayer, Zoltan, Vermeulen, Michael, Duin, Mark van, van de Woestijne, Pieter, Nasserinejad, Kazem, Saraci, Elona, D'Agostino, Mattia, Gay, Francesca, van der Velden, Vincent H.J., Van De Donk, Niels WCJ, Broijl, Annemiek, Sonneveld, Pieter, Zweegman, Sonja, Cupedo, Tom
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
MAF Translocations Are Enriched in NDMM Patients with Elevated Levels of Circulating Tumor Cells Suggesting a Genetic Basis for Aggressive Disease Course
Fokkema, Cathelijne, de Jong, Madelon M.E., Tahri, Sabrin, Hofste Op Bruinink, Davine, Kellermayer, Zoltan, den Hollander, Chelsea, Vermeulen, Michael, Papazian, Natalie, Duin, Mark van, Hoogenboezem, Remco, Wevers, Michiel J.W., van der Velden, Vincent H.J., Sanders, Mathijs A., Broijl, Annemiek, Sonneveld, Pieter, Cupedo, Tom
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article