A Context-Dependent Role for the RNF146 Ubiquitin Ligase in Wingless/Wnt Signaling in Drosophila
Wang, Zhenghan, Tacchelly-Benites, Ofelia, Noble, Geoffrey P, Johnson, Megan K, Gagné, Jean-Philippe, Poirier, Guy G, Ahmed, Yashi
Published in Genetics (Austin) (01.03.2019)
Published in Genetics (Austin) (01.03.2019)
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Journal Article
Comparative genetic screens in human cells reveal new regulatory mechanisms in WNT signaling
Lebensohn, Andres M, Dubey, Ramin, Neitzel, Leif R, Tacchelly-Benites, Ofelia, Yang, Eungi, Marceau, Caleb D, Davis, Eric M, Patel, Bhaven B, Bahrami-Nejad, Zahra, Travaglini, Kyle J, Ahmed, Yashi, Lee, Ethan, Carette, Jan E, Rohatgi, Rajat
Published in eLife (20.12.2016)
Published in eLife (20.12.2016)
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Journal Article
Dual Roles for Membrane Association of Drosophila Axin in Wnt Signaling
Wang, Zhenghan, Tacchelly-Benites, Ofelia, Yang, Eungi, Ahmed, Yashi
Published in PLoS genetics (01.12.2016)
Published in PLoS genetics (01.12.2016)
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Journal Article
Wnt pathway activation by ADP-ribosylation
Yang, Eungi, Tacchelly-Benites, Ofelia, Wang, Zhenghan, Randall, Michael P., Tian, Ai, Benchabane, Hassina, Freemantle, Sarah, Pikielny, Claudio, Tolwinski, Nicholas S., Lee, Ethan, Ahmed, Yashi
Published in Nature communications (03.05.2016)
Published in Nature communications (03.05.2016)
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Journal Article
Axin phosphorylation in both Wnt-off and Wnt-on states requires the tumor suppressor APC
Tacchelly-Benites, Ofelia, Wang, Zhenghan, Yang, Eungi, Benchabane, Hassina, Tian, Ai, Randall, Michael P, Ahmed, Yashi
Published in PLoS genetics (06.02.2018)
Published in PLoS genetics (06.02.2018)
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Journal Article
A Quantification of Pathway Components Supports a Novel Model of Hedgehog Signal Transduction
Farzan, Shohreh F., Stegman, Melanie A., Ogden, Stacey K., Ascano, Manuel, Black, Kendall E., Tacchelly, Ofelia, Robbins, David J.
Published in The Journal of biological chemistry (16.10.2009)
Published in The Journal of biological chemistry (16.10.2009)
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Journal Article
Toggling a conformational switch in Wnt/β-catenin signaling: Regulation of Axin phosphorylation
Tacchelly-Benites, Ofelia, Wang, Zhenghan, Yang, Eungi, Lee, Ethan, Ahmed, Yashi
Published in BioEssays (01.12.2013)
Published in BioEssays (01.12.2013)
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Journal Article
Toggling a conformational switch in Wnt/β-catenin signaling: regulation of Axin phosphorylation. The phosphorylation state of Axin controls its scaffold function in two Wnt pathway protein complexes
Tacchelly-Benites, Ofelia, Wang, Zhenghan, Yang, Eungi, Lee, Ethan, Ahmed, Yashi
Published in BioEssays (01.12.2013)
Published in BioEssays (01.12.2013)
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Journal Article
Abstract PR05: Systematic forward genetic screens in haploid human cells reveal new players and regulatory mechanisms in Wnt signaling
Lebensohn, Andres M., Dubey, Ramin, Neitzel, Leif R., Tacchelly, Ofelia, Marceau, Caleb D., Bahrami, Zahra, Hansen, Amanda G., Ahmed, Yashi, Lee, Ethan, Carette, Jan, Rohatgi, Rajat
Published in Molecular cancer research (01.04.2016)
Published in Molecular cancer research (01.04.2016)
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Journal Article
Abstract 973: Tankyrase inhibition represses Wnt signaling and lung cancer growth
Busch, Alexander M., Johnson, Kevin C., Tacchelly, Ofelia, Wang, Zhenghan, Ahmed, Yashi F., Dmitrovsky, Ethan, Freemantle, Sarah J.
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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Journal Article
The ADP-ribose polymerase Tankyrase regulates adult intestinal stem cell proliferation during homeostasis in Drosophila
Wang, Zhenghan, Tian, Ai, Benchabane, Hassina, Tacchelly-Benites, Ofelia, Yang, Eungi, Nojima, Hisashi, Ahmed, Yashi
Published in Development (Cambridge) (15.05.2016)
Published in Development (Cambridge) (15.05.2016)
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Journal Article
Wnt/Wingless Pathway Activation Is Promoted by a Critical Threshold of Axin Maintained by the Tumor Suppressor APC and the ADP-Ribose Polymerase Tankyrase
Wang, Zhenghan, Tacchelly-Benites, Ofelia, Yang, Eungi, Thorne, Curtis A, Nojima, Hisashi, Lee, Ethan, Ahmed, Yashi
Published in Genetics (Austin) (01.05.2016)
Published in Genetics (Austin) (01.05.2016)
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Journal Article
Toggling a conformational switch in Wnt/[beta]-catenin signaling: Regulation of Axin phosphorylation
Tacchelly-Benites, Ofelia, Wang, Zhenghan, Yang, Eungi, Lee, Ethan, Ahmed, Yashi
Published in BioEssays (01.12.2013)
Published in BioEssays (01.12.2013)
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Journal Article