Achieving Life through Death: Redox Biology of Lipid Peroxidation in Ferroptosis
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Published in Cell chemical biology (16.04.2020)
Published in Cell chemical biology (16.04.2020)
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Redox lipid reprogramming commands susceptibility of macrophages and microglia to ferroptotic death
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Published in Nature chemical biology (01.03.2020)
Published in Nature chemical biology (01.03.2020)
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Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis
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Published in Nature chemical biology (01.01.2017)
Published in Nature chemical biology (01.01.2017)
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Excessive phospholipid peroxidation distinguishes ferroptosis from other cell death modes including pyroptosis
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Published in Cell death & disease (27.10.2020)
Published in Cell death & disease (27.10.2020)
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Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma
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Published in The Journal of clinical investigation (01.08.2018)
Published in The Journal of clinical investigation (01.08.2018)
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Ferroptotic cell death and TLR4/Trif signaling initiate neutrophil recruitment after heart transplantation
Li, Wenjun, Feng, Guoshuai, Gauthier, Jason M, Lokshina, Inessa, Higashikubo, Ryuji, Evans, Sarah, Liu, Xinping, Hassan, Adil, Tanaka, Satona, Cicka, Markus, Hsiao, Hsi-Min, Ruiz-Perez, Daniel, Bredemeyer, Andrea, Gross, Richard W, Mann, Douglas L, Tyurina, Yulia Y, Gelman, Andrew E, Kagan, Valerian E, Linkermann, Andreas, Lavine, Kory J, Kreisel, Daniel
Published in The Journal of clinical investigation (01.06.2019)
Published in The Journal of clinical investigation (01.06.2019)
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Ferroptotic cell death triggered by conjugated linolenic acids is mediated by ACSL1
Beatty, Alexander, Singh, Tanu, Tyurina, Yulia Y., Tyurin, Vladimir A., Samovich, Svetlana, Nicolas, Emmanuelle, Maslar, Kristen, Zhou, Yan, Cai, Kathy Q., Tan, Yinfei, Doll, Sebastian, Conrad, Marcus, Subramanian, Aravind, Bayır, Hülya, Kagan, Valerian E., Rennefahrt, Ulrike, Peterson, Jeffrey R.
Published in Nature communications (14.04.2021)
Published in Nature communications (14.04.2021)
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Iron Chaperone Poly rC Binding Protein 1 Protects Mouse Liver From Lipid Peroxidation and Steatosis
Protchenko, Olga, Baratz, Ethan, Jadhav, Shyamalagauri, Li, Fengmin, Shakoury‐Elizeh, Minoo, Gavrilova, Oksana, Ghosh, Manik C., Cox, James E., Maschek, J. Alan, Tyurin, Vladimir A., Tyurina, Yulia Y., Bayir, Hülya, Aron, Allegra T., Chang, Christopher J., Kagan, Valerian E., Philpott, Caroline C.
Published in Hepatology (Baltimore, Md.) (01.03.2021)
Published in Hepatology (Baltimore, Md.) (01.03.2021)
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FINO2 initiates ferroptosis through GPX4 inactivation and iron oxidation
Gaschler, Michael M., Andia, Alexander A., Liu, Hengrui, Csuka, Joleen M., Hurlocker, Brisa, Vaiana, Christopher A., Heindel, Daniel W., Zuckerman, Dylan S., Bos, Pieter H., Reznik, Eduard, Ye, Ling F., Tyurina, Yulia Y., Lin, Annie J., Shchepinov, Mikhail S., Chan, Amy Y., Peguero-Pereira, Eveliz, Fomich, Maksim A., Daniels, Jacob. D., Bekish, Andrei V., Shmanai, Vadim V., Kagan, Valerian E., Mahal, Lara K., Woerpel, K. A., Stockwell, Brent R.
Published in Nature chemical biology (01.05.2018)
Published in Nature chemical biology (01.05.2018)
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PLA2G6 guards placental trophoblasts against ferroptotic injury
Beharier, Ofer, Tyurin, Vladimir A., Goff, Julie P., Guerrero-Santoro, Jennifer, Kajiwara, Kazuhiro, Chu, Tianjiao, Tyurina, Yulia Y., St Croix, Claudette M., Wallace, Callen T., Parry, Samuel, Parks, W. Tony, Kagan, Valerian E., Sadovsky, Yoel
Published in Proceedings of the National Academy of Sciences - PNAS (03.11.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (03.11.2020)
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Reactivation of dormant tumor cells by modified lipids derived from stress-activated neutrophils
Perego, Michela, Tyurin, Vladimir A, Tyurina, Yulia Y, Yellets, Jonathan, Nacarelli, Timothy, Lin, Cindy, Nefedova, Yulia, Kossenkov, Andrew, Liu, Qin, Sreedhar, Sreesha, Pass, Harvey, Roth, Johannes, Vogl, Thomas, Feldser, David, Zhang, Rugang, Kagan, Valerian E, Gabrilovich, Dmitry I
Published in Science translational medicine (02.12.2020)
Published in Science translational medicine (02.12.2020)
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Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells
Chu, Charleen T., Ji, Jing, Dagda, Ruben K., Jiang, Jian Fei, Tyurina, Yulia Y., Kapralov, Alexandr A., Tyurin, Vladimir A., Yanamala, Naveena, Shrivastava, Indira H., Mohammadyani, Dariush, Qiang Wang, Kent Zhi, Zhu, Jianhui, Klein-Seetharaman, Judith, Balasubramanian, Krishnakumar, Amoscato, Andrew A., Borisenko, Grigory, Huang, Zhentai, Gusdon, Aaron M., Cheikhi, Amin, Steer, Erin K., Wang, Ruth, Baty, Catherine, Watkins, Simon, Bahar, Ivet, Bayır, Hülya, Kagan, Valerian E.
Published in Nature cell biology (01.10.2013)
Published in Nature cell biology (01.10.2013)
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Elucidating the contribution of mitochondrial glutathione to ferroptosis in cardiomyocytes
Jang, Sehwan, Chapa-Dubocq, Xavier R., Tyurina, Yulia Y., St Croix, Claudette M., Kapralov, Alexandr A., Tyurin, Vladimir A., Bayır, Hülya, Kagan, Valerian E., Javadov, Sabzali
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Published in Redox biology (01.09.2021)
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15LO1 dictates glutathione redox changes in asthmatic airway epithelium to worsen type 2 inflammation
Nagasaki, Tadao, Schuyler, Alexander J, Zhao, Jinming, Samovich, Svetlana N, Yamada, Kazuhiro, Deng, Yanhan, Ginebaugh, Scott P, Christenson, Stephanie A, Woodruff, Prescott G, Fahy, John V, Trudeau, John B, Stoyanovsky, Detcho, Ray, Anuradha, Tyurina, Yulia Y, Kagan, Valerian E, Wenzel, Sally E
Published in The Journal of clinical investigation (04.01.2022)
Published in The Journal of clinical investigation (04.01.2022)
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Van San, Emily, Debruyne, Angela C., Veeckmans, Geraldine, Tyurina, Yulia Y., Tyurin, Vladimir A., Zheng, Hao, Choi, Sze Men, Augustyns, Koen, van Loo, Geert, Michalke, Bernhard, Venkataramani, Vivek, Toyokuni, Shinya, Bayir, Hülya, Vandenabeele, Peter, Hassannia, Behrouz, Vanden Berghe, Tom
Published in Cell death and differentiation (01.09.2023)
Published in Cell death and differentiation (01.09.2023)
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Phospholipids of APOE lipoproteins activate microglia in an isoform-specific manner in preclinical models of Alzheimer’s disease
Fitz, Nicholas F., Nam, Kyong Nyon, Wolfe, Cody M., Letronne, Florent, Playso, Brittany E., Iordanova, Bistra E., Kozai, Takashi D. Y., Biedrzycki, Richard J., Kagan, Valerian E., Tyurina, Yulia Y., Han, Xianlin, Lefterov, Iliya, Koldamova, Radosveta
Published in Nature communications (07.06.2021)
Published in Nature communications (07.06.2021)
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Keratinocyte death by ferroptosis initiates skin inflammation after UVB exposure
Vats, Kavita, Kruglov, Oleg, Mizes, Alicia, Samovich, Svetlana N., Amoscato, Andrew A., Tyurin, Vladimir A., Tyurina, Yulia Y., Kagan, Valerian E., Bunimovich, Yuri L.
Published in Redox biology (01.11.2021)
Published in Redox biology (01.11.2021)
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PEBP1 acts as a rheostat between prosurvival autophagy and ferroptotic death in asthmatic epithelial cells
Zhao, Jinming, Dar, Haider H., Deng, Yanhan, St. Croix, Claudette M., Li, Zhipeng, Minami, Yoshinori, Shrivastava, Indira H., Tyurina, Yulia Y., Etling, Emily, Rosenbaum, Joel C., Nagasaki, Tadao, Trudeau, John B., Watkins, Simon C., Bahar, Ivet, Bayır, Hülya, VanDemark, Andy P., Kagan, Valerian E., Wenzel, Sally E.
Published in Proceedings of the National Academy of Sciences - PNAS (23.06.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (23.06.2020)
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Direct Mapping of Phospholipid Ferroptotic Death Signals in Cells and Tissues by Gas Cluster Ion Beam Secondary Ion Mass Spectrometry (GCIB‐SIMS)
Sparvero, Louis J., Tian, Hua, Amoscato, Andrew A., Sun, Wan‐Yang, Anthonymuthu, Tamil S., Tyurina, Yulia Y., Kapralov, Oleksandr, Javadov, Sabzali, He, Rong‐Rong, Watkins, Simon C., Winograd, Nicholas, Kagan, Valerian E., Bayır, Hülya
Published in Angewandte Chemie International Edition (17.05.2021)
Published in Angewandte Chemie International Edition (17.05.2021)
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