Unfractionated heparin inhibits live wild type SARS‐CoV‐2 cell infectivity at therapeutically relevant concentrations
Tree, Julia A., Turnbull, Jeremy E., Buttigieg, Karen R., Elmore, Michael J., Coombes, Naomi, Hogwood, John, Mycroft‐West, Courtney J., Lima, Marcelo A., Skidmore, Mark A., Karlsson, Richard, Chen, Yen‐Hsi, Yang, Zhang, Spalluto, Cosma Mirella, Staples, Karl J., Yates, Edwin A., Gray, Elaine, Singh, Dave, Wilkinson, Tom, Page, Clive P., Carroll, Miles W.
Published in British Journal of Pharmacology (01.02.2021)
Published in British Journal of Pharmacology (01.02.2021)
Get full text
Journal Article
Web Resource
Intrinsic tryptophan fluorescence spectroscopy reliably determines galectin-ligand interactions
Sindrewicz, Paulina, Li, Xiaoxin, Yates, Edwin A., Turnbull, Jeremy E., Lian, Lu-Yun, Yu, Lu-Gang
Published in Scientific reports (14.08.2019)
Published in Scientific reports (14.08.2019)
Get full text
Journal Article
How members of the human gut microbiota overcome the sulfation problem posed by glycosaminoglycans
Cartmell, Alan, Lowe, Elisabeth C., Baslé, Arnaud, Firbank, Susan J., Ndeh, Didier A., Murray, Heath, Terrapon, Nicolas, Lombard, Vincent, Henrissat, Bernard, Turnbull, Jeremy E., Czjzek, Mirjam, Gilbert, Harry J., Bolam, David N.
Published in Proceedings of the National Academy of Sciences - PNAS (03.07.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (03.07.2017)
Get full text
Journal Article
Modular Synthesis of Heparan Sulfate Oligosaccharides for Structure−Activity Relationship Studies
Arungundram, Sailaja, Al-Mafraji, Kanar, Asong, Jinkeng, Leach, Franklin E, Amster, I. Jonathan, Venot, Andre, Turnbull, Jeremy E, Boons, Geert-Jan
Published in Journal of the American Chemical Society (02.12.2009)
Published in Journal of the American Chemical Society (02.12.2009)
Get full text
Journal Article
Editorial: C. elegans as an emerging model of pharmacological innovation
Huang, Zebo, Ma, Long, Mishra, Ajay, Turnbull, Jeremy E., Tu, Haijun
Published in Frontiers in pharmacology (27.09.2022)
Published in Frontiers in pharmacology (27.09.2022)
Get full text
Journal Article
Shotgun ion mobility mass spectrometry sequencing of heparan sulfate saccharides
Miller, Rebecca L., Guimond, Scott E., Schwörer, Ralf, Zubkova, Olga V., Tyler, Peter C., Xu, Yongmei, Liu, Jian, Chopra, Pradeep, Boons, Geert-Jan, Grabarics, Márkó, Manz, Christian, Hofmann, Johanna, Karlsson, Niclas G., Turnbull, Jeremy E., Struwe, Weston B., Pagel, Kevin
Published in Nature communications (20.03.2020)
Published in Nature communications (20.03.2020)
Get full text
Journal Article
Sulf1 and Sulf2 Differentially Modulate Heparan Sulfate Proteoglycan Sulfation during Postnatal Cerebellum Development: Evidence for Neuroprotective and Neurite Outgrowth Promoting Functions
Kalus, Ina, Rohn, Susanne, Puvirajesinghe, Tania M, Guimond, Scott E, Eyckerman-Kölln, Pieter J, Ten Dam, Gerdy, van Kuppevelt, Toin H, Turnbull, Jeremy E, Dierks, Thomas
Published in PloS one (08.10.2015)
Published in PloS one (08.10.2015)
Get full text
Journal Article
Chemokine CXCL4 interactions with extracellular matrix proteoglycans mediate widespread immune cell recruitment independent of chemokine receptors
Gray, Anna L., Karlsson, Richard, Roberts, Abigail R.E., Ridley, Amanda J.L., Pun, Nabina, Khan, Bakhtbilland, Lawless, Craig, Luís, Rafael, Szpakowska, Martyna, Chevigné, Andy, Hughes, Catherine E., Medina-Ruiz, Laura, Birchenough, Holly L., Mulholland, Iashia Z., Salanga, Catherina L., Yates, Edwin A., Turnbull, Jeremy E., Handel, Tracy M., Graham, Gerard J., Jowitt, Thomas A., Schiessl, Ingo, Richter, Ralf P., Miller, Rebecca L., Dyer, Douglas P.
Published in Cell reports (Cambridge) (31.01.2023)
Published in Cell reports (Cambridge) (31.01.2023)
Get full text
Journal Article
The Hyperlipidaemic Drug Fenofibrate Significantly Reduces Infection by SARS-CoV-2 in Cell Culture Models
Davies, Scott P, Mycroft-West, Courtney J, Pagani, Isabel, Hill, Harriet J, Chen, Yen-Hsi, Karlsson, Richard, Bagdonaite, Ieva, Guimond, Scott E, Stamataki, Zania, De Lima, Marcelo Andrade, Turnbull, Jeremy E, Yang, Zhang, Vicenzi, Elisa, Skidmore, Mark A, Khanim, Farhat L, Richardson, Alan
Published in Frontiers in pharmacology (06.08.2021)
Published in Frontiers in pharmacology (06.08.2021)
Get full text
Journal Article
Correction: Heparanase inhibition as a systemic approach to protect the endothelial glycocalyx and prevent microvascular complications in diabetes
Gamez, Monica, E Elhegni, Hesham, Fawaz, Sarah, Ho Ho, Kwan, W Campbell, Neill, A Copland, David, L Onions, Karen, J Butler, Matthew, J Wasson, Elizabeth, Crompton, Michael, D Ramnath, Raina, Qiu, Yan, Yamaguchi, Yu, P Arkill, Kenton, O Bates, David, E Turnbull, Jeremy, V Zubkova, Olga, I Welsh, Gavin, Atan, Denize, C Satchell, Simon, R Foster, Rebecca
Published in Cardiovascular diabetology (20.02.2024)
Published in Cardiovascular diabetology (20.02.2024)
Get full text
Journal Article
Heparin Precursors with Reduced Anticoagulant Properties Retain Antiviral and Protective Effects That Potentiate the Efficacy of Sofosbuvir against Zika Virus Infection in Human Neural Progenitor Cells
Pagani, Isabel, Ottoboni, Linda, Panina-Bordignon, Paola, Martino, Gianvito, Poli, Guido, Taylor, Sarah, Turnbull, Jeremy E., Yates, Edwin, Vicenzi, Elisa
Published in Pharmaceuticals (Basel, Switzerland) (29.09.2023)
Published in Pharmaceuticals (Basel, Switzerland) (29.09.2023)
Get full text
Journal Article
Heparanase inhibition as a systemic approach to protect the endothelial glycocalyx and prevent microvascular complications in diabetes
Gamez, Monica, Elhegni, Hesham E, Fawaz, Sarah, Ho, Kwan Ho, Campbell, Neill W, Copland, David A, Onions, Karen L, Butler, Matthew J, Wasson, Elizabeth J, Crompton, Michael, Ramnath, Raina D, Qiu, Yan, Yamaguchi, Yu, Arkill, Kenton P, Bates, David O, Turnbull, Jeremy E, Zubkova, Olga V, Welsh, Gavin I, Atan, Denize, Satchell, Simon C, Foster, Rebecca R
Published in Cardiovascular diabetology (01.02.2024)
Published in Cardiovascular diabetology (01.02.2024)
Get full text
Journal Article
Validation of Recombinant Heparan Sulphate Reagents for CNS Repair
Lindsay, Susan L, Sherrard Smith, Rebecca, Yates, Edwin A, Cartwright, Colin, Thacker, Bryan E, Turnbull, Jeremy E, Glass, Charles A, Barnett, Susan C
Published in Biology (Basel, Switzerland) (01.03.2023)
Published in Biology (Basel, Switzerland) (01.03.2023)
Get full text
Journal Article
2-O Heparan Sulfate Sulfation by Hs2st Is Required for Erk/Mapk Signalling Activation at the Mid-Gestational Mouse Telencephalic Midline
Chan, Wai Kit, Howe, Katherine, Clegg, James M, Guimond, Scott E, Price, David J, Turnbull, Jeremy E, Pratt, Thomas
Published in PloS one (15.06.2015)
Published in PloS one (15.06.2015)
Get full text
Journal Article
Heparan sulfotransferases Hs6st1 and Hs2st keep Erk in check for mouse corpus callosum development
Clegg, James M, Conway, Christopher D, Howe, Kathy M, Price, David J, Mason, John O, Turnbull, Jeremy E, Basson, M Albert, Pratt, Thomas
Published in The Journal of neuroscience (05.02.2014)
Published in The Journal of neuroscience (05.02.2014)
Get full text
Journal Article
Chemically modified, non-anticoagulant heparin derivatives are potent galectin-3 binding inhibitors and inhibit circulating galectin-3-promoted metastasis
Duckworth, Carrie A, Guimond, Scott E, Sindrewicz, Paulina, Hughes, Ashley J, French, Neil S, Lian, Lu-Yun, Yates, Edwin A, Pritchard, D Mark, Rhodes, Jonathan M, Turnbull, Jeremy E, Yu, Lu-Gang
Published in Oncotarget (15.09.2015)
Published in Oncotarget (15.09.2015)
Get full text
Journal Article
Novel Mechanisms of Fibroblast Growth Factor Receptor 1 Regulation by Extracellular Matrix Protein Anosmin-1
Hu, Youli, Guimond, Scott E., Travers, Paul, Cadman, Steven, Hohenester, Erhard, Turnbull, Jeremy E., Kim, Soo-Hyun, Bouloux, Pierre-Marc
Published in The Journal of biological chemistry (23.10.2009)
Published in The Journal of biological chemistry (23.10.2009)
Get full text
Journal Article
Specific Heparan Sulfate Structures Modulate FGF10-mediated Submandibular Gland Epithelial Morphogenesis and Differentiation
Patel, Vaishali N., Likar, Karen M., Zisman-Rozen, Simona, Cowherd, Samuel N., Lassiter, Keyonica S., Sher, Ifat, Yates, Edwin A., Turnbull, Jeremy E., Ron, Dina, Hoffman, Matthew P.
Published in The Journal of biological chemistry (04.04.2008)
Published in The Journal of biological chemistry (04.04.2008)
Get full text
Journal Article