DNA repair targeted therapy: The past or future of cancer treatment?
Gavande, Navnath S, VanderVere-Carozza, Pamela S, Hinshaw, Hilary D, Jalal, Shadia I, Sears, Catherine R, Pawelczak, Katherine S, Turchi, John J
Published in Pharmacology & therapeutics (Oxford) (01.04.2016)
Published in Pharmacology & therapeutics (Oxford) (01.04.2016)
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Journal Article
Modulating DNA Repair Pathways to Improve Precision Genome Engineering
Pawelczak, Katherine S, Gavande, Navnath S, VanderVere-Carozza, Pamela S, Turchi, John J
Published in ACS chemical biology (16.02.2018)
Published in ACS chemical biology (16.02.2018)
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Journal Article
DNA Repair: From Genome Maintenance to Biomarker and Therapeutic Target
JALAL, Shadia, EARLEY, Jennifer N, TURCHI, John J
Published in Clinical cancer research (15.11.2011)
Published in Clinical cancer research (15.11.2011)
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Journal Article
Discovery and development of novel DNA-PK inhibitors by targeting the unique Ku–DNA interaction
Gavande, Navnath S, VanderVere-Carozza, Pamela S, Pawelczak, Katherine S, Mendoza-Munoz, Pamela, Vernon, Tyler L, Hanakahi, Leslyn A, Summerlin, Matthew, Dynlacht, Joseph R, Farmer, Annabelle H, Sears, Catherine R, Nasrallah, Nawar Al, Garrett, Joy, Turchi, John J
Published in Nucleic acids research (18.11.2020)
Published in Nucleic acids research (18.11.2020)
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The novel, small-molecule DNA methylation inhibitor SGI-110 as an ovarian cancer chemosensitizer
Fang, Fang, Munck, Joanne, Tang, Jessica, Taverna, Pietro, Wang, Yinu, Miller, David F B, Pilrose, Jay, Choy, Gavin, Azab, Mohammad, Pawelczak, Katherine S, VanderVere-Carozza, Pamela, Wagner, Michael, Lyons, John, Matei, Daniela, Turchi, John J, Nephew, Kenneth P
Published in Clinical cancer research (15.12.2014)
Published in Clinical cancer research (15.12.2014)
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Extracellular Tissue Transglutaminase Activates Noncanonical NF-κB Signaling and Promotes Metastasis in Ovarian Cancer
Yakubov, Bakhtiyor, Chelladurai, Bhadrani, Schmitt, Jordan, Emerson, Robert, Turchi, John J, Matei, Daniela
Published in Neoplasia (New York, N.Y.) (01.06.2013)
Published in Neoplasia (New York, N.Y.) (01.06.2013)
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Recent Advances in the Development of Non-PIKKs Targeting Small Molecule Inhibitors of DNA Double-Strand Break Repair
Kelm, Jeremy M, Samarbakhsh, Amirreza, Pillai, Athira, VanderVere-Carozza, Pamela S, Aruri, Hariprasad, Pandey, Deepti S, Pawelczak, Katherine S, Turchi, John J, Gavande, Navnath S
Published in Frontiers in oncology (06.04.2022)
Published in Frontiers in oncology (06.04.2022)
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In Vivo Targeting Replication Protein A for Cancer Therapy
VanderVere-Carozza, Pamela S, Gavande, Navnath S, Jalal, Shadia I, Pollok, Karen E, Ekinci, Elmira, Heyza, Joshua, Patrick, Steve M, Masters, Andi, Turchi, John J, Pawelczak, Katherine S
Published in Frontiers in oncology (18.02.2022)
Published in Frontiers in oncology (18.02.2022)
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Journal Article
Characterization and initial demonstration of in vivo efficacy of a novel heat-activated metalloenediyne anti-cancer agent
Garrett, Joy, Metzger, Erin, Dewhirst, Mark W., Pollok, Karen E., Turchi, John J., Le Poole, Isabelle C., Couch, Kira, Lew, Logan, Sinn, Anthony, Zaleski, Jeffrey M., Dynlacht, Joseph R.
Published in International journal of hyperthermia (2022)
Published in International journal of hyperthermia (2022)
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Journal Article
Ku–DNA binding inhibitors modulate the DNA damage response in response to DNA double-strand breaks
Mendoza-Munoz, Pamela L, Gavande, Navnath S, VanderVere-Carozza, Pamela S, Pawelczak, Katherine S, Dynlacht, Joseph R, Garrett, Joy E, Turchi, John J
Published in NAR cancer (01.03.2023)
Published in NAR cancer (01.03.2023)
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Journal Article
Targeting ovarian tumor cell adhesion mediated by tissue transglutaminase
Khanna, May, Chelladurai, Bhadrani, Gavini, Aruna, Li, Liwei, Shao, Minghai, Courtney, David, Turchi, John J, Matei, Daniela, Meroueh, Samy
Published in Molecular cancer therapeutics (01.04.2011)
Published in Molecular cancer therapeutics (01.04.2011)
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The mechanistic role of cardiac glycosides in DNA damage response and repair signaling
Ainembabazi, Diana, Zhang, Youwei, Turchi, John J.
Published in Cellular and molecular life sciences : CMLS (01.09.2023)
Published in Cellular and molecular life sciences : CMLS (01.09.2023)
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ATR inhibition overcomes platinum tolerance associated with ERCC1- and p53-deficiency by inducing replication catastrophe
Heyza, Joshua R, Ekinci, Elmira, Lindquist, Jacob, Lei, Wen, Yunker, Christopher, Vinothkumar, Vilvanathan, Rowbotham, Rachelle, Polin, Lisa, Snider, Natalie G, Van Buren, Eric, Watza, Donovan, Back, Jessica B, Chen, Wei, Mamdani, Hirva, Schwartz, Ann G, Turchi, John J, Bepler, Gerold, Patrick, Steve M
Published in NAR cancer (01.03.2023)
Published in NAR cancer (01.03.2023)
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