The Neutralization Breadth of HIV-1 Develops Incrementally over Four Years and Is Associated with CD4+ T Cell Decline and High Viral Load during Acute Infection
GRAY, Elin S, MADIGA, Maphuti C, ABDOOL KARIM, Salim S, MORRIS, Lynn, HERMANUS, Tandile, MOORE, Penny L, WIBMER, Constantinos Kurt, TUMBA, Nancy L, WERNER, Lise, MLISANA, Koleka, SIBEKO, Sengeziwe, WILLIAMSON, Carolyn
Published in Journal of Virology (01.05.2011)
Published in Journal of Virology (01.05.2011)
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Evolution of an HIV glycan–dependent broadly neutralizing antibody epitope through immune escape
Moore, Penny L, Gray, Elin S, Wibmer, C Kurt, Bhiman, Jinal N, Nonyane, Molati, Sheward, Daniel J, Hermanus, Tandile, Bajimaya, Shringkhala, Tumba, Nancy L, Abrahams, Melissa-Rose, Lambson, Bronwen E, Ranchobe, Nthabeleng, Ping, Lihua, Ngandu, Nobubelo, Karim, Quarraisha Abdool, Karim, Salim S Abdool, Swanstrom, Ronald I, Seaman, Michael S, Williamson, Carolyn, Morris, Lynn
Published in Nature medicine (01.11.2012)
Published in Nature medicine (01.11.2012)
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Covalent binding of human two-domain CD4 to an HIV-1 subtype C SOSIP.664 trimer modulates its structural dynamics
Tumba, Nancy L., Naicker, Previn, Stoychev, Stoyan, Killick, Mark A., Owen, Gavin R., Papathanasopoulos, Maria A.
Published in Biochemical and biophysical research communications (05.07.2022)
Published in Biochemical and biophysical research communications (05.07.2022)
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Ibogaine administration following repeated morphine administration upregulates myelination markers 2', 3'-cyclic nucleotide 3'-phosphodiesterase (CNP) and myelin basic protein (MBP) mRNA and protein expression in the internal capsule of Sprague Dawley rats
Govender, Demi, Moloko, Leila, Papathanasopoulos, Maria, Tumba, Nancy, Owen, Gavin, Calvey, Tanya
Published in Frontiers in neuroscience (24.07.2024)
Published in Frontiers in neuroscience (24.07.2024)
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Viral escape from HIV-1 neutralizing antibodies drives increased plasma neutralization breadth through sequential recognition of multiple epitopes and immunotypes
Wibmer, Constantinos Kurt, Bhiman, Jinal N, Gray, Elin S, Tumba, Nancy, Abdool Karim, Salim S, Williamson, Carolyn, Morris, Lynn, Moore, Penny L
Published in PLoS pathogens (01.10.2013)
Published in PLoS pathogens (01.10.2013)
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Strain-Specific V3 and CD4 Binding Site Autologous HIV-1 Neutralizing Antibodies Select Neutralization-Resistant Viruses
Moody, M. Anthony, Gao, Feng, Gurley, Thaddeus C., Amos, Joshua D., Kumar, Amit, Hora, Bhavna, Marshall, Dawn J., Whitesides, John F., Xia, Shi-Mao, Parks, Robert, Lloyd, Krissey E., Hwang, Kwan-Ki, Lu, Xiaozhi, Bonsignori, Mattia, Finzi, Andrés, Vandergrift, Nathan A., Alam, S. Munir, Ferrari, Guido, Shen, Xiaoying, Tomaras, Georgia D., Kamanga, Gift, Cohen, Myron S., Sam, Noel E., Kapiga, Saidi, Gray, Elin S., Tumba, Nancy L., Morris, Lynn, Zolla-Pazner, Susan, Gorny, Miroslaw K., Mascola, John R., Hahn, Beatrice H., Shaw, George M., Sodroski, Joseph G., Liao, Hua-Xin, Montefiori, David C., Hraber, Peter T., Korber, Bette T., Haynes, Barton F.
Published in Cell host & microbe (09.09.2015)
Published in Cell host & microbe (09.09.2015)
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Polyclonal B Cell Responses to Conserved Neutralization Epitopes in a Subset of HIV-1-Infected Individuals
TOMARAS, Georgia D, BINLEY, James M, DECKER, Julie, WIBMER, Constantinos Kurt, FENG GAO, ALAM, S. Munir, EASTERBROOK, Philippa, KARIM, Salim Abdool, KAMANGA, Gift, CRUMP, John A, COHEN, Myron, SHAW, George M, GRAY, Elin S, MASCOLA, John R, HAYNES, Barton F, MONTEFIORI, David C, MORRIS, Lynn, CROOKS, Emma T, OSAWA, Keiko, MOORE, Penny L, TUMBA, Nancy, TONG, Tommy, XIAOYING SHEN, YATES, Nicole L
Published in Journal of Virology (01.11.2011)
Published in Journal of Virology (01.11.2011)
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Potent and Broad Neutralization of HIV-1 Subtype C by Plasma Antibodies Targeting a Quaternary Epitope Including Residues in the V2 Loop
MOORE, Penny L, GRAY, Elin S, SIBEKO, Sengeziwe, MLISANA, Koleka, ABDOOL KARIM, Salim S, WILLIAMSON, Carolyn, PINTER, Abraham, MORRIS, Lynn, SHEWARD, Daniel, MADIGA, Maphuti, RANCHOBE, Nthabeleng, ZHONG LAI, HONNEN, William J, NONYANE, Molati, TUMBA, Nancy, HERMANUS, Tandile
Published in Journal of Virology (01.04.2011)
Published in Journal of Virology (01.04.2011)
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Potent and broad HIV-neutralizing antibodies in memory B cells and plasma
Williams, LaTonya D, Ofek, Gilad, Schätzle, Sebastian, McDaniel, Jonathan R, Lu, Xiaozhi, Nicely, Nathan I, Wu, Liming, Lougheed, Caleb S, Bradley, Todd, Louder, Mark K, McKee, Krisha, Bailer, Robert T, O'Dell, Sijy, Georgiev, Ivelin S, Seaman, Michael S, Parks, Robert J, Marshall, Dawn J, Anasti, Kara, Yang, Guang, Nie, Xiaoyan, Tumba, Nancy L, Wiehe, Kevin, Wagh, Kshitij, Korber, Bette, Kepler, Thomas B, Munir Alam, S, Morris, Lynn, Kamanga, Gift, Cohen, Myron S, Bonsignori, Mattia, Xia, Shi-Mao, Montefiori, David C, Kelsoe, Garnett, Gao, Feng, Mascola, John R, Moody, M Anthony, Saunders, Kevin O, Liao, Hua-Xin, Tomaras, Georgia D, Georgiou, George, Haynes, Barton F
Published in Science immunology (27.01.2017)
Published in Science immunology (27.01.2017)
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Immunization with HIV-1 trimeric SOSIP.664 BG505 or founder virus C (FVCEnv) covalently complexed to two-domain CD4S60C elicits cross-clade neutralizing antibodies in New Zealand white rabbits
Tumba, Nancy L., Owen, Gavin R., Killick, Mark A., Papathanasopoulos, Maria A.
Published in Vaccine: X (01.12.2022)
Published in Vaccine: X (01.12.2022)
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UCLA1, a Synthetic Derivative of a gp120 RNA Aptamer, Inhibits Entry of Human Immunodeficiency Virus Type 1 Subtype C
MUFHANDU, Hazel T, GRAY, Elin S, MADIGA, Maphuti C, TUMBA, Nancy, ALEXANDRE, Kabamba B, KHOZA, Thandeka, WIBMER, Constantinos Kurt, MOORE, Penny L, MORRIS, Lynn, KHATI, Makobetsa
Published in Journal of Virology (01.05.2012)
Published in Journal of Virology (01.05.2012)
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Correction: Features of Recently Transmitted HIV-1 Clade C Viruses that Impact Antibody Recognition: Implications for Active and Passive Immunization
Rademeyer, Cecilia, Korber, Bette, Seaman, Michael S, Giorgi, Elena E, Thebus, Ruwayhida, Robles, Alexander, Sheward, Daniel J, Wagh, Kshitij, Garrity, Jetta, Carey, Brittany R, Gao, Hongmei, Greene, Kelli M, Tang, Haili, Bandawe, Gama P, Marais, Jinny C, Diphoko, Thabo E, Hraber, Peter, Tumba, Nancy, Moore, Penny L, Gray, Glenda E, Kublin, James, McElrath, M Juliana, Vermeulen, Marion, Middelkoop, Keren, Bekker, Linda-Gail, Hoelscher, Michael, Maboko, Leonard, Makhema, Joseph, Robb, Merlin L, Karim, Salim Abdool, Karim, Quarraisha Abdool, Kim, Jerome H, Hahn, Beatrice H, Gao, Feng, Swanstrom, Ronald, Morris, Lynn, Montefiori, David C, Williamson, Carolyn
Published in PLoS pathogens (01.09.2017)
Published in PLoS pathogens (01.09.2017)
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Amino Acid Changes in the HIV-1 gp41 Membrane Proximal Region Control Virus Neutralization Sensitivity
Bradley, Todd, Trama, Ashley, Tumba, Nancy, Gray, Elin, Lu, Xiaozhi, Madani, Navid, Jahanbakhsh, Fatemeh, Eaton, Amanda, Xia, Shi-Mao, Parks, Robert, Lloyd, Krissey E., Sutherland, Laura L., Scearce, Richard M., Bowman, Cindy M., Barnett, Susan, Abdool-Karim, Salim S., Boyd, Scott D., Melillo, Bruno, Smith, Amos B., Sodroski, Joseph, Kepler, Thomas B., Alam, S.Munir, Gao, Feng, Bonsignori, Mattia, Liao, Hua-Xin, Moody, M. Anthony, Montefiori, David, Santra, Sampa, Morris, Lynn, Haynes, Barton F.
Published in EBioMedicine (01.10.2016)
Published in EBioMedicine (01.10.2016)
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Journal Article
Structure and immune recognition of trimeric pre-fusion HIV-1 Env
Pancera, Marie, Zhou, Tongqing, Druz, Aliaksandr, Georgiev, Ivelin S., Soto, Cinque, Gorman, Jason, Huang, Jinghe, Acharya, Priyamvada, Chuang, Gwo-Yu, Ofek, Gilad, Stewart-Jones, Guillaume B. E., Stuckey, Jonathan, Bailer, Robert T., Joyce, M. Gordon, Louder, Mark K., Tumba, Nancy, Yang, Yongping, Zhang, Baoshan, Cohen, Myron S., Haynes, Barton F., Mascola, John R., Morris, Lynn, Munro, James B., Blanchard, Scott C., Mothes, Walther, Connors, Mark, Kwong, Peter D.
Published in Nature (London) (23.10.2014)
Published in Nature (London) (23.10.2014)
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Journal Article
Features of Recently Transmitted HIV-1 Clade C Viruses that Impact Antibody Recognition: Implications for Active and Passive Immunization
Rademeyer, Cecilia, Korber, Bette, Seaman, Michael S, Giorgi, Elena E, Thebus, Ruwayhida, Robles, Alexander, Sheward, Daniel J, Wagh, Kshitij, Garrity, Jetta, Carey, Brittany R, Gao, Hongmei, Greene, Kelli M, Tang, Haili, Bandawe, Gama P, Marais, Jinny C, Diphoko, Thabo E, Hraber, Peter, Tumba, Nancy, Moore, Penny L, Gray, Glenda E, Kublin, James, McElrath, M Juliana, Vermeulen, Marion, Middelkoop, Keren, Bekker, Linda-Gail, Hoelscher, Michael, Maboko, Leonard, Makhema, Joseph, Robb, Merlin L, Abdool Karim, Salim, Abdool Karim, Quarraisha, Kim, Jerome H, Hahn, Beatrice H, Gao, Feng, Swanstrom, Ronald, Morris, Lynn, Montefiori, David C, Williamson, Carolyn
Published in PLoS pathogens (01.07.2016)
Published in PLoS pathogens (01.07.2016)
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A Fusion Intermediate gp41 Immunogen Elicits Neutralizing Antibodies to HIV-1
Lai, Rachel P.J., Hock, Miriam, Radzimanowski, Jens, Tonks, Paul, Hulsik, David Lutje, Effantin, Gregory, Seilly, David J., Dreja, Hanna, Kliche, Alexander, Wagner, Ralf, Barnett, Susan W., Tumba, Nancy, Morris, Lynn, LaBranche, Celia C., Montefiori, David C., Seaman, Michael S., Heeney, Jonathan L., Weissenhorn, Winfried
Published in The Journal of biological chemistry (24.10.2014)
Published in The Journal of biological chemistry (24.10.2014)
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Viral Escape from HIV-1 Neutralizing Antibodies Drives Increased Plasma Neutralization Breadth through Sequential Recognition of Multiple Epitopes and Immunotypes: e1003738
Wibmer, Constantinos Kurt, Bhiman, Jinal N, Gray, Elin S, Tumba, Nancy, Karim, Salim SAbdool, Williamson, Carolyn, Morris, Lynn, Moore, Penny L
Published in PLoS pathogens (01.10.2013)
Published in PLoS pathogens (01.10.2013)
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Journal Article
Structure and immune recognition of trimeric prefusion HIV-1 Env
Pancera, Marie, Zhou, Tongqing, Druz, Aliaksandr, Georgiev, Ivelin S., Soto, Cinque, Gorman, Jason, Huang, Jinghe, Acharya, Priyamvada, Chuang, Gwo-Yu, Ofek, Gilad, Stewart-Jones, Guillaume B. E., Stuckey, Jonathan, Bailer, Robert T., Joyce, M. Gordon, Louder, Mark K., Tumba, Nancy, Yang, Yongping, Zhang, Baoshan, Cohen, Myron S., Haynes, Barton F., Mascola, John R., Morris, Lynn, Munro, James B., Blanchard, Scott C., Mothes, Walther, Connors, Mark, Kwong, Peter D.
Published in Nature (London) (08.10.2014)
Published in Nature (London) (08.10.2014)
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Comparative analysis of expression and secretion of placental leptin in mammals
Zhao, Jing, Kunz, Thomas H, Tumba, Nancy, Clamon Schulz, Laura, Li, Chris, Reeves, Monica, Widmaier, Eric P
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01.08.2003)
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01.08.2003)
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Comparative analysis of expression and secretion of placental leptin in mammals
JING ZHAO, KUNZ, Thomas H, TUMBA, Nancy, SCHULZ, Laura Clamon, LI, Chris, REEVES, Monica, WIDMAIER, Eric P
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01.08.2003)
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Published in American journal of physiology. Regulatory, integrative and comparative physiology (01.08.2003)
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