Prediction of time-dependent CYP3A4 drug–drug interactions by physiologically based pharmacokinetic modelling: Impact of inactivation parameters and enzyme turnover
Rowland Yeo, K., Walsky, R.L., Jamei, M., Rostami-Hodjegan, A., Tucker, G.T.
Published in European journal of pharmaceutical sciences (14.06.2011)
Published in European journal of pharmaceutical sciences (14.06.2011)
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Development of CYP2D6 and CYP3A4 in the first year of life
Johnson, T N, Tucker, G T, Rostami-Hodjegan, A
Published in Clinical pharmacology and therapeutics (01.05.2008)
Published in Clinical pharmacology and therapeutics (01.05.2008)
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Inter‐individual variability in levels of human microsomal protein and hepatocellularity per gram of liver
Wilson, Z. E., Rostami‐Hodjegan, A., Burn, J. L., Tooley, A., Boyle, J, Ellis, S. W., Tucker, G. T.
Published in British journal of clinical pharmacology (01.10.2003)
Published in British journal of clinical pharmacology (01.10.2003)
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Modified-release hydrocortisone for circadian therapy: a proof-of-principle study in dexamethasone-suppressed normal volunteers
Newell-Price, J., Whiteman, M., Rostami-Hodjegan, A., Darzy, K., Shalet, S., Tucker, G. T., Ross, R. J. M.
Published in Clinical endocrinology (Oxford) (01.01.2008)
Published in Clinical endocrinology (Oxford) (01.01.2008)
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Impact of the Pharmaceutical Sciences on Health Care: A Reflection over the Past 50 Years
Rowland, Malcolm, Noe, Christian R., Smith, Dennis A., Tucker, G.T., Crommelin, Daan J.A., Peck, Carl C., Rocci Jr, Mario L., Besançon, Luc, Shah, Vinod P.
Published in Journal of pharmaceutical sciences (01.11.2012)
Published in Journal of pharmaceutical sciences (01.11.2012)
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MECHANISM-BASED INACTIVATION OF CYP2D6 BY METHYLENEDIOXYMETHAMPHETAMINE
HEYDARI, A, ROWLAND YEO, K, LENNARD, M. S, ELLIS, S. W, TUCKER, G. T, ROSTAMI-HODJEGAN, A
Published in Drug metabolism and disposition (01.11.2004)
Published in Drug metabolism and disposition (01.11.2004)
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Circadian hydrocortisone infusions in patients with adrenal insufficiency and congenital adrenal hyperplasia
Merza, Z., Rostami-Hodjegan, A., Memmott, A., Doane, A., Ibbotson, V., Newell-Price, J., Tucker, G. T., Ross, R. J.
Published in Clinical endocrinology (Oxford) (01.07.2006)
Published in Clinical endocrinology (Oxford) (01.07.2006)
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Current trends and future challenges of electrolytes for sodium-ion batteries
Vignarooban, K., Kushagra, R., Elango, A., Badami, P., Mellander, B.-E., Xu, X., Tucker, T.G., Nam, C., Kannan, A.M.
Published in International journal of hydrogen energy (30.01.2016)
Published in International journal of hydrogen energy (30.01.2016)
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A critical evaluation of the experimental design of studies of mechanism based enzyme inhibition, with implications for in vitro-in vivo extrapolation
Ghanbari, F, Rowland-Yeo, K, Bloomer, J C, Clarke, S E, Lennard, M S, Tucker, G T, Rostami-Hodjegan, A
Published in Current drug metabolism (01.04.2006)
Published in Current drug metabolism (01.04.2006)
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Disparity in Holoprotein/Apoprotein Ratios of Different Standards Used for Immunoquantification of Hepatic Cytochrome P450 Enzymes
PERRETT, H. F, BARTER, Z. E, JONES, B. C, YAMAZAKI, H, TUCKER, G. T, ROSTAMI-HODJEGAN, A
Published in Drug metabolism and disposition (01.10.2007)
Published in Drug metabolism and disposition (01.10.2007)
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Metformin and cimetidine: Physiologically based pharmacokinetic modelling to investigate transporter mediated drug–drug interactions
Burt, H.J., Neuhoff, S., Almond, L., Gaohua, L., Harwood, M.D., Jamei, M., Rostami-Hodjegan, A., Tucker, G.T., Rowland-Yeo, K.
Published in European journal of pharmaceutical sciences (10.06.2016)
Published in European journal of pharmaceutical sciences (10.06.2016)
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Contribution of midazolam and its 1-hydroxy metabolite to preoperative sedation in children: a pharmacokinetic-pharmacodynamic analysis
Johnson, T.N., Rostami-Hodjegan, A., Goddard, J.M., Tanner, M.S., Tucker, G.T.
Published in British journal of anaesthesia : BJA (01.09.2002)
Published in British journal of anaesthesia : BJA (01.09.2002)
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Oxidation of Methamphetamine and Methylenedioxymethamphetamine by CYP2D6
LIN, L. Y, DI STEFANO, E. W, SCHMITZ, D. A, HSU, L, ELLIS, S. W, LENNARD, M. S, TUCKER, G. T, CHO, A. K
Published in Drug metabolism and disposition (01.09.1997)
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Published in Drug metabolism and disposition (01.09.1997)
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The pharmacokinetics of methadone in healthy subjects and opiate users
Wolff, K., Rostami‐Hodjegan, A., Shires, S., Hay, A. W. M., Feely, M., Calvert, R., Raistrick, D., Tucker, G. T.
Published in British journal of clinical pharmacology (01.10.1997)
Published in British journal of clinical pharmacology (01.10.1997)
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A discordance between cytochrome P450 2D6 genotype and phenotype in patients undergoing methadone maintenance treatment
Shiran, M. R., Chowdry, J., Rostami‐Hodjegan, A., Ellis, S. W., Lennard, M. S., Iqbal, M. Z., Lagundoye, O., Seivewright, N., Tucker, G. T.
Published in British journal of clinical pharmacology (01.08.2003)
Published in British journal of clinical pharmacology (01.08.2003)
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Physiologically based modelling of inhibition of metabolism and assessment of the relative potency of drug and metabolite: dextromethorphan vs. dextrorphan using quinidine inhibition
Moghadamnia, A. A., Rostami‐Hodjegan, A., Abdul‐Manap, R., Wright, C. E., Morice, A. H., Tucker, G. T.
Published in British journal of clinical pharmacology (01.07.2003)
Published in British journal of clinical pharmacology (01.07.2003)
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