Pathological angiogenesis in retinopathy engages cellular senescence and is amenable to therapeutic elimination via BCL-xL inhibition
Crespo-Garcia, Sergio, Tsuruda, Pamela R., Dejda, Agnieszka, Ryan, Rathi D., Fournier, Frederik, Chaney, Shawnta Y., Pilon, Frederique, Dogan, Taner, Cagnone, Gael, Patel, Priyanka, Buscarlet, Manuel, Dasgupta, Sonali, Girouard, Gabrielle, Rao, Surabhi R., Wilson, Ariel M., O’Brien, Robert, Juneau, Rachel, Guber, Vera, Dubrac, Alexandre, Beausejour, Christian, Armstrong, Scott, Mallette, Frederick A., Yohn, Christopher B., Joyal, Jean-Sebastien, Marquess, Dan, Beltran, Pedro J., Sapieha, Przemyslaw
Published in Cell metabolism (06.04.2021)
Published in Cell metabolism (06.04.2021)
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Journal Article
The menthol receptor TRPM8 is the principal detector of environmental cold
Basbaum, Allan I, Tsuruda, Pamela R, Bautista, Diana M, Jordt, Sven-Eric, Stucky, Cheryl L, Julius, David, Glazer, Joshua M, Siemens, Jan
Published in Nature (12.07.2007)
Published in Nature (12.07.2007)
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Journal Article
TRPA1 Mediates the Inflammatory Actions of Environmental Irritants and Proalgesic Agents
Bautista, Diana M., Jordt, Sven-Eric, Nikai, Tetsuro, Tsuruda, Pamela R., Read, Andrew J., Poblete, Jeannie, Yamoah, Ebenezer N., Basbaum, Allan I., Julius, David
Published in Cell (24.03.2006)
Published in Cell (24.03.2006)
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Journal Article
Therapeutic targeting of cellular senescence in diabetic macular edema: preclinical and phase 1 trial results
Crespo-Garcia, Sergio, Fournier, Frédérik, Diaz-Marin, Roberto, Klier, Sharon, Ragusa, Derek, Masaki, Lauren, Cagnone, Gael, Blot, Guillaume, Hafiane, Ikhlas, Dejda, Agnieszka, Rizk, Rana, Juneau, Rachel, Buscarlet, Manuel, Chorfi, Sarah, Patel, Priyanka, Beltran, Pedro J., Joyal, Jean-Sebastien, Rezende, Flavio A., Hata, Masayuki, Nguyen, Alex, Sullivan, Lynne, Damiano, Jason, Wilson, Ariel M., Mallette, Frédérick A., David, Nathaniel E., Ghosh, Anirvan, Tsuruda, Pamela R., Dananberg, Jamie, Sapieha, Przemyslaw
Published in Nature medicine (01.02.2024)
Published in Nature medicine (01.02.2024)
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Journal Article
The star-nosed mole reveals clues to the molecular basis of mammalian touch
Gerhold, Kristin A, Pellegrino, Maurizio, Tsunozaki, Makoto, Morita, Takeshi, Leitch, Duncan B, Tsuruda, Pamela R, Brem, Rachel B, Catania, Kenneth C, Bautista, Diana M
Published in PloS one (30.01.2013)
Published in PloS one (30.01.2013)
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Journal Article
Pungent agents from Szechuan peppers excite sensory neurons by inhibiting two-pore potassium channels
Nicoll, Roger A, Tsuruda, Pamela R, Milstein, Aaron D, Bautista, Diana M, Zorn, Julie A, Julius, David, Sigal, Yaron M, Garrison, Jennifer L
Published in Nature neuroscience (01.07.2008)
Published in Nature neuroscience (01.07.2008)
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Journal Article
Coiled Coils Direct Assembly of a Cold-Activated TRP Channel
Tsuruda, Pamela R., Julius, David, Minor, Daniel L.
Published in Neuron (Cambridge, Mass.) (20.07.2006)
Published in Neuron (Cambridge, Mass.) (20.07.2006)
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Journal Article
Relative contributions of norepinephrine and serotonin transporters to antinociceptive synergy between monoamine reuptake inhibitors and morphine in the rat formalin model
Shen, Fei, Tsuruda, Pamela R, Smith, Jacqueline A M, Obedencio, Glenmar P, Martin, William J
Published in PloS one (30.09.2013)
Published in PloS one (30.09.2013)
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Journal Article
Modulation of Postendocytic Sorting of G Protein-Coupled Receptors
Whistler, Jennifer L., Enquist, Johan, Marley, Aaron, Fong, Jamie, Gladher, Fredrik, Tsuruda, Pamela, Murray, Stephen R., von Zastrow, Mark
Published in Science (American Association for the Advancement of Science) (26.07.2002)
Published in Science (American Association for the Advancement of Science) (26.07.2002)
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Journal Article
Discovery of Axelopran (TD-1211): A Peripherally Restricted μ‑Opioid Receptor Antagonist
Long, Daniel D, Armstrong, Scott R, Beattie, David T, Campbell, Christina B, Church, Timothy J, Colson, Pierre-Jean, Dalziel, Sean M, Jacobsen, John R, Jiang, Lan, Obedencio, Glenmar P, Rapta, Miroslav, Saito, Daisuke, Stergiades, Ioanna, Tsuruda, Pamela R, Van Dyke, Priscilla M, Vickery, Ross G
Published in ACS medicinal chemistry letters (12.12.2019)
Published in ACS medicinal chemistry letters (12.12.2019)
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Journal Article
Prediction of human serotonin and norepinephrine transporter occupancy of duloxetine by pharmacokinetic/pharmacodynamic modeling in the rat
Bourdet, David L, Tsuruda, Pamela R, Obedencio, Glenmar P, Smith, Jacqueline A M
Published in The Journal of pharmacology and experimental therapeutics (01.04.2012)
Published in The Journal of pharmacology and experimental therapeutics (01.04.2012)
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Journal Article
The in vivo pharmacodynamics of the novel opioid receptor antagonist, TD-1211, in models of opioid-induced gastrointestinal and CNS activity
Armstrong, Scott R., Campbell, Christina B., Richardson, Carrie L., Vickery, Ross G., Tsuruda, Pamela R., Long, Daniel D., Hegde, Sharath S., Beattie, David T.
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.06.2013)
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.06.2013)
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Journal Article
Influence of ligand binding kinetics on functional inhibition of human recombinant serotonin and norepinephrine transporters
Tsuruda, Pamela R., Yung, Joey, Martin, William J., Chang, Ray, Mai, Ngoc, Smith, Jacqueline A.M.
Published in Journal of pharmacological and toxicological methods (01.03.2010)
Published in Journal of pharmacological and toxicological methods (01.03.2010)
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Journal Article
Neuroanatomical Evidence for Segregation of Nerve Fibers Conveying Light Touch and Pain Sensation in Eimer's Organ of the Mole
Marasco, Paul D., Tsuruda, Pamela R., Bautista, Diana M., Julius, David, Catania, Kenneth C.
Published in Proceedings of the National Academy of Sciences - PNAS (13.06.2006)
Published in Proceedings of the National Academy of Sciences - PNAS (13.06.2006)
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Journal Article
Fine structure of Eimer's organ in the coast mole (Scapanus orarius)
Marasco, Paul D., Tsuruda, Pamela R., Bautista, Diana M., Catania, Kenneth C.
Published in Anatomical record (Hoboken, N.J. : 2007) (01.05.2007)
Published in Anatomical record (Hoboken, N.J. : 2007) (01.05.2007)
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Journal Article
5-HT 4 receptor agonist mediated enhancement of cognitive function in vivo and amyloid precursor protein processing in vitro: A pharmacodynamic and pharmacokinetic assessment
Shen, Fei, Smith, Jacqueline A.M., Chang, Ray, Bourdet, David L., Tsuruda, Pamela R., Obedencio, Glenmar P., Beattie, David T.
Published in Neuropharmacology (01.07.2011)
Published in Neuropharmacology (01.07.2011)
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Journal Article
5-HT4 receptor agonist mediated enhancement of cognitive function in vivo and amyloid precursor protein processing in vitro: A pharmacodynamic and pharmacokinetic assessment
Shen, Fei, Smith, Jacqueline A.M., Chang, Ray, Bourdet, David L., Tsuruda, Pamela R., Obedencio, Glenmar P., Beattie, David T.
Published in Neuropharmacology (01.07.2011)
Published in Neuropharmacology (01.07.2011)
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Journal Article
5-HT sub(4 receptor agonist mediated enhancement of cognitive function in vivo and amyloid precursor protein processing in vitro: A pharmacodynamic and pharmacokinetic assessment)
Shen, Fei, Smith, Jacqueline AM, Chang, Ray, Bourdet, David L, Tsuruda, Pamela R, Obedencio, Glenmar P, Beattie, David T
Published in Neuropharmacology (01.08.2011)
Published in Neuropharmacology (01.08.2011)
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Journal Article