Suvorexant and mirtazapine improve chronic pain-related changes in parameters of sleep and voluntary physical performance in mice with sciatic nerve ligation
Ito, Hisakatsu, Tsuneki, Hiroshi, Sasaoka, Toshiyasu, Toyooka, Naoki, Matsuo, Mitsuhiro, Yamazaki, Mitsuaki
Published in PloS one (25.02.2022)
Published in PloS one (25.02.2022)
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Eplerenone prevented obesity-induced inflammasome activation and glucose intolerance
Wada, Tsutomu, Ishikawa, Akari, Watanabe, Eri, Nakamura, Yuto, Aruga, Yusuke, Hasegawa, Hayate, Onogi, Yasuhiro, Honda, Hiroe, Nagai, Yoshinori, Takatsu, Kiyoshi, Ishii, Yoko, Sasahara, Masakiyo, Koya, Daisuke, Tsuneki, Hiroshi, Sasaoka, Toshiyasu
Published in Journal of endocrinology (01.12.2017)
Published in Journal of endocrinology (01.12.2017)
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Journal Article
Estrogen regulates sex-specific localization of regulatory T cells in adipose tissue of obese female mice
Ishikawa, Akari, Wada, Tsutomu, Nishimura, Sanshiro, Ito, Tetsuo, Okekawa, Akira, Onogi, Yasuhiro, Watanabe, Eri, Sameshima, Azusa, Tanaka, Tomoko, Tsuneki, Hiroshi, Saito, Shigeru, Sasaoka, Toshiyasu
Published in PloS one (02.04.2020)
Published in PloS one (02.04.2020)
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Journal Article
Platelet-derived growth factor signaling in pericytes promotes hypothalamic inflammation and obesity
Okekawa, Akira, Wada, Tsutomu, Onogi, Yasuhiro, Takeda, Yuki, Miyazawa, Yuichiro, Sasahara, Masakiyo, Tsuneki, Hiroshi, Sasaoka, Toshiyasu
Published in Molecular medicine (Cambridge, Mass.) (05.02.2024)
Published in Molecular medicine (Cambridge, Mass.) (05.02.2024)
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Journal Article
Spironolactone Improves Glucose and Lipid Metabolism by Ameliorating Hepatic Steatosis and Inflammation and Suppressing Enhanced Gluconeogenesis Induced by High-Fat and High-Fructose Diet
Wada, Tsutomu, Kenmochi, Hiroki, Miyashita, Yusuke, Sasaki, Motohiro, Ojima, Minoru, Sasahara, Masakiyo, Koya, Daisuke, Tsuneki, Hiroshi, Sasaoka, Toshiyasu
Published in Endocrinology (Philadelphia) (01.05.2010)
Published in Endocrinology (Philadelphia) (01.05.2010)
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Journal Article
Deletion of platelet-derived growth factor receptor β suppresses tumorigenesis in metabolic dysfunction-associated steatohepatitis (MASH) mice with diabetes
Wada, Tsutomu, Takeda, Yuki, Okekawa, Akira, Komatsu, Go, Iwasa, Yuichi, Onogi, Yasuhiro, Takasaki, Ichiro, Hamashima, Takeru, Sasahara, Masakiyo, Tsuneki, Hiroshi, Sasaoka, Toshiyasu
Published in Scientific reports (11.10.2024)
Published in Scientific reports (11.10.2024)
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Journal Article
Impact of central and peripheral estrogen treatment on anxiety and depression phenotypes in a mouse model of postmenopausal obesity
Wada, Tsutomu, Sameshima, Azusa, Yonezawa, Rika, Morita, Mayuko, Sawakawa, Kanae, Tsuneki, Hiroshi, Sasaoka, Toshiyasu, Saito, Shigeru
Published in PloS one (27.12.2018)
Published in PloS one (27.12.2018)
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Ameliorating effects of compounds derived from Salvia miltiorrhiza root extract on microcirculatory disturbance and target organ injury by ischemia and reperfusion
Han, Jing-Yan, Fan, Jing-Yu, Horie, Yoshinori, Miura, Soichiro, Cui, De-Hua, Ishii, Hiromasa, Hibi, Toshifumi, Tsuneki, Hiroshi, Kimura, Ikuko
Published in Pharmacology & therapeutics (Oxford) (01.02.2008)
Published in Pharmacology & therapeutics (Oxford) (01.02.2008)
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Journal Article
Oestrogen receptor α in T cells controls the T cell immune profile and glucose metabolism in mouse models of gestational diabetes mellitus
Tanaka, Tomoko, Wada, Tsutomu, Uno, Kimie, Ogihara, Saki, Ie, Hiromi, Okekawa, Akira, Ishikawa, Akari, Ito, Tetsuo, Miyazawa, Yuichiro, Sameshima, Azusa, Onogi, Yasuhiro, Tsuneki, Hiroshi, Sasahara, Masakiyo, Nakashima, Akitoshi, Saito, Shigeru, Sasaoka, Toshiyasu
Published in Diabetologia (01.07.2021)
Published in Diabetologia (01.07.2021)
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Journal Article
Central versus peripheral impact of estradiol on the impaired glucose metabolism in ovariectomized mice on a high-fat diet
Yonezawa, Rika, Wada, Tsutomu, Matsumoto, Natsumi, Morita, Mayuko, Sawakawa, Kanae, Ishii, Yoko, Sasahara, Masakiyo, Tsuneki, Hiroshi, Saito, Shigeru, Sasaoka, Toshiyasu
Published in American journal of physiology: endocrinology and metabolism (15.08.2012)
Published in American journal of physiology: endocrinology and metabolism (15.08.2012)
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Stromal cell-derived factor 1 (SDF1) attenuates platelet-derived growth factor-B (PDGF-B)-induced vascular remodeling for adipose tissue expansion in obesity
Watanabe, Eri, Wada, Tsutomu, Okekawa, Akira, Kitamura, Fuka, Komatsu, Go, Onogi, Yasuhiro, Yamamoto, Seiji, Sasahara, Masakiyo, Kitada, Munehiro, Koya, Daisuke, Tsuneki, Hiroshi, Sasaoka, Toshiyasu
Published in Angiogenesis (London) (01.11.2020)
Published in Angiogenesis (London) (01.11.2020)
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Journal Article
Hypothalamic orexin prevents non-alcoholic steatohepatitis and hepatocellular carcinoma in obesity
Tsuneki, Hiroshi, Maeda, Takahiro, Takata, Shinjiro, Sugiyama, Masanori, Otsuka, Koyuki, Ishizuka, Hinako, Onogi, Yasuhiro, Tokai, Emi, Koshida, Chiaki, Kon, Kanta, Takasaki, Ichiro, Hamashima, Takeru, Sasahara, Masakiyo, Rudich, Assaf, Koya, Daisuke, Sakurai, Takeshi, Yanagisawa, Masashi, Yamanaka, Akihiro, Wada, Tsutomu, Sasaoka, Toshiyasu
Published in Cell reports (Cambridge) (18.10.2022)
Published in Cell reports (Cambridge) (18.10.2022)
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Journal Article
Hypothalamic orexin prevents hepatic insulin resistance via daily bidirectional regulation of autonomic nervous system in mice
Tsuneki, Hiroshi, Tokai, Emi, Nakamura, Yuya, Takahashi, Keisuke, Fujita, Mikio, Asaoka, Takehiro, Kon, Kanta, Anzawa, Yuuki, Wada, Tsutomu, Takasaki, Ichiro, Kimura, Kumi, Inoue, Hiroshi, Yanagisawa, Masashi, Sakurai, Takeshi, Sasaoka, Toshiyasu
Published in Diabetes (New York, N.Y.) (01.02.2015)
Published in Diabetes (New York, N.Y.) (01.02.2015)
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Journal Article
Pro-inflammatory macrophages coupled with glycolysis remodel adipose vasculature by producing platelet-derived growth factor-B in obesity
Onogi, Yasuhiro, Wada, Tsutomu, Okekawa, Akira, Matsuzawa, Takatoshi, Watanabe, Eri, Ikeda, Keisuke, Nakano, Minoru, Kitada, Munehiro, Koya, Daisuke, Tsuneki, Hiroshi, Sasaoka, Toshiyasu
Published in Scientific reports (20.01.2020)
Published in Scientific reports (20.01.2020)
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Journal Article
A transdermal treatment with MC903 ameliorates diet-induced obesity by reducing visceral fat and increasing myofiber thickness and energy consumption in mice
Wada, Tsutomu, Miyazawa, Yuichiro, Ikurumi, Misa, Fuse, Kento, Okekawa, Akira, Onogi, Yasuhiro, Saito, Shigeru, Tsuneki, Hiroshi, Sasaoka, Toshiyasu
Published in Nutrition & metabolism (11.02.2023)
Published in Nutrition & metabolism (11.02.2023)
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Journal Article
Aldosterone Inhibits Insulin-Induced Glucose Uptake by Degradation of Insulin Receptor Substrate (IRS) 1 and IRS2 via a Reactive Oxygen Species-Mediated Pathway in 3T3-L1 Adipocytes
Wada, Tsutomu, Ohshima, Satoshi, Fujisawa, Eriko, Koya, Daisuke, Tsuneki, Hiroshi, Sasaoka, Toshiyasu
Published in Endocrinology (Philadelphia) (01.04.2009)
Published in Endocrinology (Philadelphia) (01.04.2009)
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Journal Article
AS1949490, an inhibitor of 5′-lipid phosphatase SHIP2, promotes protein kinase C-dependent stabilization of brain-derived neurotrophic factor mRNA in cultured cortical neurons
Tsuneki, Hiroshi, Yoshida, Hitomi, Okamoto, Kentaro, Yamaguchi, Misako, Endo, Kosuke, Nakano, Ayumi, Tsuda, Masaaki, Toyooka, Naoki, Wada, Tsutomu, Sasaoka, Toshiyasu
Published in European journal of pharmacology (15.05.2019)
Published in European journal of pharmacology (15.05.2019)
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Journal Article
Chronotherapeutic effect of orexin antagonists on glucose metabolism in diabetic mice
Kon, Kanta, Tsuneki, Hiroshi, Ito, Hisakatsu, Takemura, Yoshinori, Sato, Kiyofumi, Yamazaki, Mitsuaki, Ishii, Yoko, Sasahara, Masakiyo, Rudich, Assaf, Maeda, Takahiro, Wada, Tsutomu, Sasaoka, Toshiyasu
Published in Journal of endocrinology (01.10.2019)
Published in Journal of endocrinology (01.10.2019)
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