Search Results - "TSUMOTO, Kouhei" :: K.UTB vyhledávací portál

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Engineering Stability, Viscosity, and Immunogenicity of Antibodies by Computational Design

by Kuroda, Daisuke, Tsumoto, Kouhei
Published in Journal of pharmaceutical sciences (01.05.2020)

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Addition of arginine hydrochloride and proline to the culture medium enhances recombinant protein expression in Brevibacillus choshinensis: The case of RBD of SARS-CoV-2 spike protein and its antibody

by Matsunaga, Ryo, Tsumoto, Kouhei
Published in Protein expression and purification (01.06.2022)

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Effects of Syringe Material and Silicone Oil Lubrication on the Stability of Pharmaceutical Proteins

by Krayukhina, Elena, Tsumoto, Kouhei, Uchiyama, Susumu, Fukui, Kiichi
Published in Journal of pharmaceutical sciences (01.02.2015)

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Analytical Method for Experimental Validation of Computer-Designed Antibody

by Tanabe, Aki, Tsumoto, Kouhei
Published in Methods in molecular biology (Clifton, N.J.) (2023)

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Effects of subclass change on the structural stability of chimeric, humanized, and human antibodies under thermal stress

by Ito, Takahiko, Tsumoto, Kouhei
Published in Protein science (01.11.2013)

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Development of novel humanized VHH synthetic libraries based on physicochemical analyses

by Nakakido, Makoto, Kinoshita, Seisho, Tsumoto, Kouhei
Published in Scientific reports (22.08.2024)

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Antibody Affinity Maturation by Computational Design

by Kuroda, Daisuke, Tsumoto, Kouhei
Published in Methods in molecular biology (Clifton, N.J.) (2018)

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Thermodynamic and molecular dynamic insights into how fusion influences peptide-tag recognition of an antibody

by Miyanabe, Kazuhiro, Yamashita, Takefumi, Tsumoto, Kouhei
Published in Scientific reports (15.04.2024)

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Thermodynamics of antibody-antigen interaction revealed by mutation analysis of antibody variable regions

by Akiba, Hiroki, Tsumoto, Kouhei
Published in Journal of biochemistry (Tokyo) (01.07.2015)

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Glycosylation of IgG-Fc: a molecular perspective

by Kiyoshi, Masato, Tsumoto, Kouhei, Ishii-Watabe, Akiko, Caaveiro, Jose M M
Published in International immunology (01.07.2017)

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Next Generation Drying Technologies for Pharmaceutical Applications

by Walters, Robert H., Bhatnagar, Bakul, Tchessalov, Serguei, Izutsu, Ken-Ichi, Tsumoto, Kouhei, Ohtake, Satoshi
Published in Journal of pharmaceutical sciences (01.09.2014)

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How the protonation state of a phosphorylated amino acid governs molecular recognition: insights from classical molecular dynamics simulations

by Kawade, Raiji, Kuroda, Daisuke, Tsumoto, Kouhei
Published in FEBS letters (01.03.2020)

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Discovery of chemical probes that suppress Wnt/β‐catenin signaling through high‐throughput screening

by Yamaguchi, Kiyoshi, Nagatoishi, Satoru, Tsumoto, Kouhei, Furukawa, Yoichi
Published in Cancer science (01.03.2020)

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Thermodynamic and computational analyses reveal the functional roles of the galloyl group of tea catechins in molecular recognition

by Takahashi, Tomoya, Nagatoishi, Satoru, Kuroda, Daisuke, Tsumoto, Kouhei
Published in PloS one (11.10.2018)

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Development of a high-throughput method to screen novel antiviral materials

by Nakakido, Makoto, Tanaka, Naoki, Shimojo, Ayako, Miyamae, Nobuhiro, Tsumoto, Kouhei
Published in PloS one (27.04.2022)

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Delicate balance among thermal stability, binding affinity, and conformational space explored by single-domain VHH antibodies

by Ikeuchi, Emina, Kuroda, Daisuke, Nakakido, Makoto, Murakami, Akikazu, Tsumoto, Kouhei
Published in Scientific reports (18.10.2021)

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Structural basis for self-assembly of a cytolytic pore lined by protein and lipid

by Tanaka, Koji, Caaveiro, Jose M.M., Morante, Koldo, González-Mañas, Juan Manuel, Tsumoto, Kouhei
Published in Nature communications (26.02.2015)

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Analysis of Pore Formation and Protein Translocation Using Large Biological Nanopores

by Watanabe, Hirokazu, Gubbiotti, Alberto, Chinappi, Mauro, Takai, Natsumi, Tanaka, Koji, Tsumoto, Kouhei, Kawano, Ryuji
Published in Analytical chemistry (Washington) (07.11.2017)

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Microsecond molecular dynamics suggest that a non-synonymous mutation, frequently observed in patients with mild symptoms in Tokyo, alters dynamics of the SARS-CoV-2 main protease

by Kuroda, Daisuke, Tsumoto, Kouhei
Published in Biophysics and Physicobiology (01.01.2021)

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Exploring designability of electrostatic complementarity at an antigen-antibody interface directed by mutagenesis, biophysical analysis, and molecular dynamics simulations

by Yoshida, Kouhei, Kuroda, Daisuke, Kiyoshi, Masato, Nakakido, Makoto, Nagatoishi, Satoru, Soga, Shinji, Shirai, Hiroki, Tsumoto, Kouhei
Published in Scientific reports (14.03.2019)

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