Development of a Scalable Synthesis of Tofogliflozin
Ohtake, Yoshihito, Emura, Takashi, Nishimoto, Masahiro, Takano, Koji, Yamamoto, Keisuke, Tsuchiya, Satoshi, Yeu, Sang-Yong, Kito, Yasushi, Kimura, Nobuaki, Takeda, Sunao, Tsukazaki, Masao, Murakata, Masatoshi, Sato, Tsutomu
Published in Journal of organic chemistry (04.03.2016)
Published in Journal of organic chemistry (04.03.2016)
Get full text
Journal Article
Discovery and biological activity of a novel class I PI3K inhibitor, CH5132799
Ohwada, Jun, Ebiike, Hirosato, Kawada, Hatsuo, Tsukazaki, Masao, Nakamura, Mitsuaki, Miyazaki, Takuya, Morikami, Kenji, Yoshinari, Kiyoshi, Yoshida, Miyuki, Kondoh, Osamu, Kuramoto, Shino, Ogawa, Kotaro, Aoki, Yuko, Shimma, Nobuo
Published in Bioorganic & medicinal chemistry letters (15.03.2011)
Published in Bioorganic & medicinal chemistry letters (15.03.2011)
Get full text
Journal Article
In vitro activity of isavuconazole against 140 reference fungal strains and 165 clinically isolated yeasts from Japan
Yamazaki, Toshikazu, Inagaki, Yukiko, Fujii, Toshihiko, Ohwada, Jun, Tsukazaki, Masao, Umeda, Isao, Kobayashi, Kazuko, Shimma, Nobuo, Page, Malcolm G.P, Arisawa, Mikio
Published in International journal of antimicrobial agents (01.10.2010)
Published in International journal of antimicrobial agents (01.10.2010)
Get full text
Journal Article
Copper-Catalyzed Oxidation of Alcohols to Aldehydes and Ketones: An Efficient, Aerobic Alternative
Markó, Istvan E., Giles, Paul R., Tsukazaki, Masao, Brown, Stephen M., Urch, Christopher J.
Published in Science (American Association for the Advancement of Science) (20.12.1996)
Published in Science (American Association for the Advancement of Science) (20.12.1996)
Get full text
Journal Article
Efficient, Ecologically Benign, Aerobic Oxidation of Alcohols
Markó, István. E, Giles, Paul R, Tsukazaki, Masao, Chellé-Regnaut, Isabelle, Gautier, Arnaud, Brown, Stephen M, Urch, Christopher J
Published in Journal of organic chemistry (02.04.1999)
Published in Journal of organic chemistry (02.04.1999)
Get full text
Journal Article
Design, synthesis and antifungal activity of a novel water soluble prodrug of antifungal triazole
Ohwada, Jun, Tsukazaki, Masao, Hayase, Tadakatsu, Oikawa, Nobuhiro, Isshiki, Yoshiaki, Fukuda, Hiroshi, Mizuguchi, Eisaku, Sakaitani, Masahiro, Shiratori, Yasuhiko, Yamazaki, Toshikazu, Ichihara, Shigeyasu, Umeda, Isao, Shimma, Nobuo
Published in Bioorganic & medicinal chemistry letters (01.01.2003)
Published in Bioorganic & medicinal chemistry letters (01.01.2003)
Get full text
Journal Article
Novel and Efficient Isomerization of Allylic Alcohols Promoted by a Tetrapropylammonium Perruthenate Catalyst
Markó, István E., Gautier, Arnaud, Tsukazaki, Masao, Llobet, Antoni, Plantalech-Mir, Elena, Urch, Christopher J., Brown, Stephen M.
Published in Angewandte Chemie International Edition (12.07.1999)
Published in Angewandte Chemie International Edition (12.07.1999)
Get full text
Journal Article
Early Process Development of CH7057288, a Benzofuran-Containing Selective NTRK Inhibitor
Oki, Tomohiro, Shiina, Junichi, Fukuda, Hiroshi, Yamawaki, Minoru, Kito, Yasushi, Tomizawa, Masaki, Iwamura, Hiroshi, Tsukazaki, Masao, Toya, Azusa, Tsuzaki, Shun, Hama, Naoto, Kawase, Akira, Nomura, Kenichi, Ito, Hisashi, Maeda, Kenji
Published in Organic process research & development (21.06.2024)
Published in Organic process research & development (21.06.2024)
Get full text
Journal Article
Development of a Scalable Manufacturing Process for Alectinib with a Concise Preparation of the Indole-Containing Tetracyclic Core
Oki, Tomohiro, Tsukazaki, Masao, Shiina, Junichi, Fukuda, Hiroshi, Yamawaki, Minoru, Kito, Yasushi, Ishizawa, Takenori, Kinoshita, Kazutomo, Hara, Sosuke, Furuichi, Noriyuki, Kawada, Hatsuo, Ito, Toshiya, Tanaka, Kota, Maruyama, Noriaki, Tamaru, Daisuke, Ichige, Takahiro, Koizumi, Masatoshi, Hosoya, Yosuke, Kimura, Masahiro, Yamaguchi, Mami, Sato, Shigeki, Miyazaki, Yuta, Toya, Azusa, Iwamura, Hiroshi, Maeda, Kenji
Published in Organic process research & development (22.10.2024)
Published in Organic process research & development (22.10.2024)
Get full text
Journal Article
Anaerobic copper-catalyzed oxidation of alcohols to aldehydes and ketones
Marko, IE, Tsukazaki, M, Giles, PR, Brown, SM, Urch, CJ
Published in Angewandte Chemie International Edition (03.11.1997)
Published in Angewandte Chemie International Edition (03.11.1997)
Get more information
Journal Article
Modification of a dihydropyrrolopyrimidine phosphoinositide 3-kinase (PI3K) inhibitor to improve oral bioavailability
Kawada, Hatsuo, Ebiike, Hirosato, Tsukazaki, Masao, Yamamoto, Shun, Koyama, Kohei, Nakamura, Mitsuaki, Morikami, Kenji, Yoshinari, Kiyoshi, Yoshida, Miyuki, Ogawa, Kotaro, Shinma, Nobuo, Tsukuda, Takuo, Ohwada, Jun
Published in Bioorganic & medicinal chemistry (15.12.2015)
Published in Bioorganic & medicinal chemistry (15.12.2015)
Get full text
Journal Article
Optimization of the phenylurea moiety in a phosphoinositide 3-kinase (PI3K) inhibitor to improve water solubility and the PK profile by introducing a solubilizing group and ortho substituents
Kawada, Hatsuo, Ebiike, Hirosato, Tsukazaki, Masao, Yamamoto, Shun, Koyama, Kohei, Nakamura, Mitsuaki, Morikami, Kenji, Yoshinari, Kiyoshi, Yoshida, Miyuki, Ogawa, Kotaro, Shimma, Nobuo, Tsukuda, Takuo, Ohwada, Jun
Published in Bioorganic & medicinal chemistry (01.07.2016)
Published in Bioorganic & medicinal chemistry (01.07.2016)
Get full text
Journal Article
Lead optimization of a dihydropyrrolopyrimidine inhibitor against phosphoinositide 3-kinase (PI3K) to improve the phenol glucuronic acid conjugation
Kawada, Hatsuo, Ebiike, Hirosato, Tsukazaki, Masao, Nakamura, Mitsuaki, Morikami, Kenji, Yoshinari, Kiyoshi, Yoshida, Miyuki, Ogawa, Kotaro, Shimma, Nobuo, Tsukuda, Takuo, Ohwada, Jun
Published in Bioorganic & medicinal chemistry letters (01.02.2013)
Published in Bioorganic & medicinal chemistry letters (01.02.2013)
Get full text
Journal Article
water soluble prodrug of a novel camptothecin analog is efficacious against breast cancer resistance protein-expressing tumor xenografts
Endo, Mika, Miwa, Masanori, Ura, Masako, Tanimura, Hiromi, Taniguchi, Kenji, Miyazaki, Yoko, Ohwada, Jun, Tsukazaki, Masao, Niizuma, Satoshi, Murata, Takeshi, Ozawa, Sawako, Suda, Hitomi, Ogawa, Kotaro, Nanba, Eitaro, Nagao, Shunsuke, Shimma, Nobuo, Yamada-Okabe, Hisafumi
Published in Cancer chemotherapy and pharmacology (2010)
Published in Cancer chemotherapy and pharmacology (2010)
Get full text
Journal Article
Synthesis of new camptothecin analogs with improved antitumor activities
NIIZUMA, Satoshi, TSUKAZAKI, Masao, YOSHINARI, Kiyoshi, ENDO, Mika, URA, Masako, TANIMURA, Hiromi, MIYAZAKI, Yoko, TAKASUKA, Tsuyoshi, KAWASHIMA, Akira, NANBA, Eitaro, NAKANO, Kounosuke, OGAWA, Kotaro, SUDA, Hitomi, KOBAYASHI, Kazuko, OKABE, Hisafumi, UMEDA, Isao, SHIMMA, Nobuo, MURATA, Takeshi, OHWADA, Jun, OZAWA, Sawako, FUKUDA, Hiroshi, MURASAKI, Chikako, KOHCHI, Masami, MORIKAMI, Kenji
Published in Bioorganic & medicinal chemistry letters (01.04.2009)
Published in Bioorganic & medicinal chemistry letters (01.04.2009)
Get full text
Journal Article
Synthesis and biological activities of a pH-dependently activated water-soluble prodrug of a novel hexacyclic camptothecin analog
Ohwada, Jun, Ozawa, Sawako, Kohchi, Masami, Fukuda, Hiroshi, Murasaki, Chikako, Suda, Hitomi, Murata, Takeshi, Niizuma, Satoshi, Tsukazaki, Masao, Ori, Kazutomo, Yoshinari, Kiyoshi, Itezono, Yoshiko, Endo, Mika, Ura, Masako, Tanimura, Hiromi, Miyazaki, Yoko, Kawashima, Akira, Nagao, Shunsuke, Namba, Eitarou, Ogawa, Koutarou, Kobayashi, Kazuko, Okabe, Hisafumi, Umeda, Isao, Shimma, Nobuo
Published in Bioorganic & medicinal chemistry letters (15.05.2009)
Published in Bioorganic & medicinal chemistry letters (15.05.2009)
Get full text
Journal Article