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Diosgenin present in fenugreek improves glucose metabolism by promoting adipocyte differentiation and inhibiting inflammation in adipose tissues

Diosgenin present in fenugreek improves glucose metabolism by promoting adipocyte differentiation and inhibiting inflammation in adipose tissues

by Uemura, Taku, Hirai, Shizuka, Mizoguchi, Noriko, Goto, Tsuyoshi, Lee, Joo‐Yong, Taketani, Keiko, Nakano, Yuki, Shono, Jinji, Hoshino, Shohei, Tsuge, Nobuaki, Narukami, Toshihiko, Takahashi, Nobuyuki, Kawada, Teruo
Published in Molecular nutrition & food research (01.11.2010)

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Preventive Activity of ar-Turmerone and Bisacurone Isolated from Turmeric Extract Against Ethanol-induced Hepatocyte Injury

Preventive Activity of ar-Turmerone and Bisacurone Isolated from Turmeric Extract Against Ethanol-induced Hepatocyte Injury

by Megumi, Chiaki, Muroyama, Koutarou, Sasako, Hiroshi, Tsuge, Nobuaki
Published in FOOD SCIENCE AND TECHNOLOGY RESEARCH (2017)

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Dissecting the Stereocontrolled Conversion of Short-Lived Sulfenic Acid by Lachrymatory Factor Synthase

Dissecting the Stereocontrolled Conversion of Short-Lived Sulfenic Acid by Lachrymatory Factor Synthase

by Arakawa, Takatoshi, Sato, Yuta, Yamada, Masayuki, Takabe, Jumpei, Moriwaki, Yoshitaka, Masamura, Noriya, Kato, Masahiro, Aoyagi, Morihiro, Kamoi, Takahiro, Terada, Tohru, Shimizu, Kentaro, Tsuge, Nobuaki, Imai, Shinsuke, Fushinobu, Shinya
Published in ACS catalysis (03.01.2020)

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single consumption of curry improved postprandial endothelial function in healthy male subjects: a randomized, controlled crossover trial

single consumption of curry improved postprandial endothelial function in healthy male subjects: a randomized, controlled crossover trial

by Nakayama, Hideki, Tsuge, Nobuaki, Sawada, Hiroshi, Masamura, Noriya, Yamada, Shohei, Satomi, Shigeki, Higashi, Yukihito
Published in Nutrition journal (28.06.2014)

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Yamogenin in fenugreek inhibits lipid accumulation through the suppression of gene expression in fatty acid synthesis in hepatocytes

Yamogenin in fenugreek inhibits lipid accumulation through the suppression of gene expression in fatty acid synthesis in hepatocytes

by Moriwaki, Sayaka, Murakami, Hiroki, Takahashi, Nobuyuki, Uemura, Taku, Taketani, Keiko, Hoshino, Shohei, Tsuge, Nobuaki, Narukami, Toshihiko, Goto, Tsuyoshi, Kawada, Teruo
Published in Bioscience, biotechnology, and biochemistry (03.07.2014)

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Dietary curcumin supplementation attenuates 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity in C57BL mice

Dietary curcumin supplementation attenuates 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity in C57BL mice

by He, Xi-Jun, Uchida, Kazuyuki, Megumi, Chiaki, Tsuge, Nobuaki, Nakayama, Hiroyuki
Published in Journal of Toxicologic Pathology (01.01.2015)

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Diosgenin attenuates inflammatory changes in the interaction between adipocytes and macrophages

Diosgenin attenuates inflammatory changes in the interaction between adipocytes and macrophages

by Hirai, Shizuka, Uemura, Taku, Mizoguchi, Noriko, Lee, Joo-Young, Taketani, Keiko, Nakano, Yuki, Hoshino, Shohei, Tsuge, Nobuaki, Narukami, Toshihiko, Yu, Rina, Takahashi, Nobuyuki, Kawada, Teruo
Published in Molecular nutrition & food research (01.06.2010)

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Structure and Bioactivity of Thiosulfinates Resulting from Suppression of Lachrymatory Factor Synthase in Onion

Structure and Bioactivity of Thiosulfinates Resulting from Suppression of Lachrymatory Factor Synthase in Onion

by Aoyagi, Morihiro, Kamoi, Takahiro, Kato, Masahiro, Sasako, Hiroshi, Tsuge, Nobuaki, Imai, Shinsuke
Published in Journal of agricultural and food chemistry (26.10.2011)

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Proton Transfer in a Reaction Catalyzed by Onion Lachrymatory Factor Synthase

Proton Transfer in a Reaction Catalyzed by Onion Lachrymatory Factor Synthase

by MASAMURA, Noriya, AOYAGI, Morihiro, TSUGE, Nobuaki, KAMOI, Takahiro, IMAI, Shinsuke
Published in Bioscience, biotechnology, and biochemistry (2012)

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An Efficient Purification Method for Quantitative Determinations of Protodioscin, Dioscin and Diosgenin in Plasma of Fenugreek-Fed Mice

An Efficient Purification Method for Quantitative Determinations of Protodioscin, Dioscin and Diosgenin in Plasma of Fenugreek-Fed Mice

by TAKETANI, Keiko, HOSHINO, Shohei, UEMURA, Taku, GOTO, Tsuyoshi, TAKAHASHI, Nobuyuki, TSUGE, Nobuaki, KAWADA, Teruo
Published in Journal of Nutritional Science and Vitaminology (2015)

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Identification of Amino Acid Residues Essential for Onion Lachrymatory Factor Synthase Activity

Identification of Amino Acid Residues Essential for Onion Lachrymatory Factor Synthase Activity

by MASAMURA, Noriya, OHASHI, Wakana, TSUGE, Nobuaki, IMAI, Shinsuke, ISHII-NAKAMURA, Anri, HIROTA, Hiroshi, NAGATA, Toshiyuki, KUMAGAI, Hidehiko
Published in Bioscience, biotechnology, and biochemistry (2012)

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Chronic intake of onion extract containing quercetin improved postprandial endothelial dysfunction in healthy men

Chronic intake of onion extract containing quercetin improved postprandial endothelial dysfunction in healthy men

by Nakayama, Hideki, Tsuge, Nobuaki, Sawada, Hiroshi, Higashi, Yukihito
Published in Journal of the American College of Nutrition (01.06.2013)

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Fenugreek with reduced bitterness prevents diet-induced metabolic disorders in rats

Fenugreek with reduced bitterness prevents diet-induced metabolic disorders in rats

by Muraki, Etsuko, Chiba, Hiroshige, Taketani, Keiko, Hoshino, Shohei, Tsuge, Nobuaki, Tsunoda, Nobuyo, Kasono, Keizo
Published in Lipids in health and disease (29.05.2012)

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Using synthesized onion lachrymatory factor to measure age-related decreases in reflex-tear secretion and ocular-surface sensation

Using synthesized onion lachrymatory factor to measure age-related decreases in reflex-tear secretion and ocular-surface sensation

by Higashihara, Hisayo, Yokoi, Norihiko, Aoyagi, Morihiro, Tsuge, Nobuaki, Imai, Shinsuke, Kinoshita, Shigeru
Published in Japanese journal of ophthalmology (01.05.2010)

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Effect of alcohol (ethanol) administration on hippocampal CA1 neuron activity in conscious rats

Effect of alcohol (ethanol) administration on hippocampal CA1 neuron activity in conscious rats

by Tanji, Momoka, Ito, Atsuko, Tajima, Sachie, Megumi, Chiaki, Hamano, Takuya, Tsuge, Nobuaki, Miki, Kenju
Published in Neuroscience research (2009)

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Diosgenin, the Main Aglycon of Fenugreek, Inhibits LXRα Activity in HepG2 Cells and Decreases Plasma and Hepatic Triglycerides in Obese Diabetic Mice

Diosgenin, the Main Aglycon of Fenugreek, Inhibits LXRα Activity in HepG2 Cells and Decreases Plasma and Hepatic Triglycerides in Obese Diabetic Mice

by Uemura, Taku, Goto, Tsuyoshi, Kang, Min-Sook, Mizoguchi, Noriko, Hirai, Shizuka, Lee, Joo-Yong, Nakano, Yuki, Shono, Jinji, Hoshino, Shohei, Taketani, Keiko, Tsuge, Nobuaki, Narukami, Toshihiko, Makishima, Makoto, Takahashi, Nobuyuki, Kawada, Teruo
Published in The Journal of nutrition (2011)

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Novel Antibiotics Pyrisulfoxin A and B Produced by Streptomyces californicus

Novel Antibiotics Pyrisulfoxin A and B Produced by Streptomyces californicus

by TSUGE, NOBUAKI, FURIHATA, KEIKO, SHIN-YA, KAZUO, HAYAKAWA, YOICHI, SETO, HARUO
Published in Journal of antibiotics (1999)

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Effect of Synthesized onion Lacrymatory Factor on Tear Dynamics in Tear Deficient Dry Eye

Effect of Synthesized onion Lacrymatory Factor on Tear Dynamics in Tear Deficient Dry Eye

by Yokoi, Norihiko, Higashihara, Hisayo, Maruyama, Kunio, Komuro, Aoi, Nishii, Masakazu, Kinoshita, Shigeru, Tsuge, Nobuaki, Imai, Shinsuke, Shiomi, Nobuo
Published in The ocular surface (01.01.2005)

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Dill seed extract improves abnormalities in lipid metabolism through peroxisome proliferator-activated receptor-α (PPAR-α) activation in diabetic obese mice

Dill seed extract improves abnormalities in lipid metabolism through peroxisome proliferator-activated receptor-α (PPAR-α) activation in diabetic obese mice

by Takahashi, Nobuyuki, Yao, Lan, Kim, Minji, Sasako, Hiroshi, Aoyagi, Morihiro, Shono, Jinji, Tsuge, Nobuaki, Goto, Tsuyoshi, Kawada, Teruo
Published in Molecular nutrition & food research (01.07.2013)

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Cinnatriacetins A and B, New Antibacterial Triacetylene Derivatives from the Fruiting Bodies of Fistulina hepatica

Cinnatriacetins A and B, New Antibacterial Triacetylene Derivatives from the Fruiting Bodies of Fistulina hepatica

by TSUGE, NOBUAKI, MORI, TOSHIYA, HAMANO, TAKUYA, TANAKA, HISASHI, SHIN-YA, KAZUO, SETO, HARUO
Published in Journal of antibiotics (1999)

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