Antitumor Activity of the Selective Pan-RAF Inhibitor TAK-632 in BRAF Inhibitor-Resistant Melanoma
NAKAMURA, Akito, ARITA, Takeo, TSUCHIYA, Shuntarou, DONELAN, Jill, CHOUITAR, Jouhara, CARIDEO, Elizabeth, GALVIN, Katherine, OKANIWA, Masanori, ISHIKAWA, Tomoyasu, YOSHIDA, Sei
Published in Cancer research (Chicago, Ill.) (01.12.2013)
Published in Cancer research (Chicago, Ill.) (01.12.2013)
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Journal Article
Non‐alcoholic steatohepatitis‐associated hepatic fibrosis and hepatocellular carcinoma in a combined mouse model of genetic modification and dietary challenge
Amano, Yuichiro, Shimizu, Fumi, Yasuno, Hironobu, Harada, Ayako, Tsuchiya, Shuntarou, Isono, Osamu, Nagabukuro, Hiroshi, Tozawa, Ryuichi
Published in Hepatology research (01.01.2017)
Published in Hepatology research (01.01.2017)
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Anti‐angiogenic and anti‐tumor effects of TAK‐593, a potent and selective inhibitor of vascular endothelial growth factor and platelet‐derived growth factor receptor tyrosine kinase
Awazu, Yoshiko, Mizutani, Akio, Nagase, Yoshinori, Tsuchiya, Shuntarou, Nakamura, Kazuhide, Kakoi, Yuichi, Kitahara, Osamu, Takeuchi, Toshiyuki, Yamasaki, Seiji, Miyamoto, Naoki, Iwata, Hidehisa, Miki, Hiroshi, Imamura, Shinichi, Hori, Akira
Published in Cancer science (01.04.2013)
Published in Cancer science (01.04.2013)
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Pharmacological evaluation of pioglitazone and candesartan cilexetil in a novel mouse model of non‐alcoholic steatohepatitis, modified choline‐deficient, amino acid‐defined diet fed low‐density lipoprotein receptor knockout mice
Tsuchiya, Shuntarou, Amano, Yuichiro, Isono, Osamu, Imai, Mayumi, Shimizu, Fumi, Asada, Mari, Imai, Shigemitsu, Harada, Ayako, Yasuhara, Yoshitaka, Tozawa, Ryuichi, Nagabukuro, Hiroshi
Published in Hepatology research (01.05.2017)
Published in Hepatology research (01.05.2017)
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Combination effects of alogliptin and pioglitazone on steatosis and hepatic fibrosis formation in a mouse model of non-alcoholic steatohepatitis
Amano, Yuichiro, Tsuchiya, Shuntarou, Imai, Mayumi, Tohyama, Kimio, Matsukawa, Jun, Isono, Osamu, Yasuno, Hironobu, Enya, Kazuaki, Koumura, Emiko, Nagabukuro, Hiroshi
Published in Biochemical and biophysical research communications (26.02.2018)
Published in Biochemical and biophysical research communications (26.02.2018)
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SAT-356-Anti-metabolic, anti-inflammatory and anti-fibrotic properties of ART-, a novel phosphodiesterase 4 inhibitor as a potential clinical candidate for non-alcoholic steatohepatitis
Amano, Yuichiro, Tsuchiya, Shuntarou, Matsumoto, Mitsuharu, Ueno, Hikaru, Nishigaki, Nobuhiro, Isono, Osamu, Hanauer, Guido, Miyawaki, Kazumasa, Tohyama, Kimio, Miyashita, Hirohisa, Imai, Mayumi, Shimizu, Fumi, Tanaka, Akira, Nagabukuro, Hiroshi
Published in Journal of hepatology (01.04.2019)
Published in Journal of hepatology (01.04.2019)
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Abstract 4247: Characterization of the selective pan-RAF inhibitor TAK-632 with antitumor activity in BRAF inhibitor-resistant melanoma
Nakamura, Akito, Arita, Takeo, Tsuchiya, Shuntarou, Donelan, Jill, Chouitar, Jouhara, Carideo, Elizabeth, Galvin, Katherine, Okaniwa, Masanori, Ishikawa, Tomoyasu, Yoshida, Sei
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Abstract 2518: TAK-733 is a Potent and Selective Inhibitor of Mammalian MEK Kinases Capable of Inducing Apoptosis in BRAF Driven Cells Both in vitro and in vivo
Fabrey, Robyn, Shawn, O'Connell, Tsuchiya, Shuntarou, Hori, Akira, Vincent, Patrick
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Published in Cancer research (Chicago, Ill.) (15.04.2010)
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Abstract 2523: BRAF is not the only predictor of sensitivity in vitro and in vivo for TAK-733, a selective potent inhibitor of MEK1/2
O'Connell, Shawn M., Tsuchiya, Shuntarou, Shi, Lihong, Fabrey, Robyn, Zhang, Lilly, Dong, Qing, Hori, Akira, Vincent, Patrick
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Published in Cancer research (Chicago, Ill.) (15.04.2010)
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Monocyclic compound
Asano, Moriteru, Maezaki, Hironobu, Banno, Hiroshi, Mizojiri, Ryo, Imai, Mayumi, Tomita, Daisuke, Gipson, Krista E, Nii, Noriyuki, Tsuchiya, Shuntarou, Tawada, Michiko, Amano, Yuichiro
Year of Publication 09.04.2019
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Year of Publication 09.04.2019
Patent
TETRAHYDROFURO[3,4-C]ISOQUINOLINES AS INHIBITORS OF PDE4
SCHMIDT, Beate, TSUCHIYA, Shuntarou, AKAO, Yuichiro, VOLLERT, Stefanie, YAMAKAWA, Hiroko, BENEDIKTUS, Ewald, HUSSONG, Ragna, NIO, Yasunori, MURAKI, Yo, AMANO, Yuichiro, ISONO, Osamu, NAGABUKURO, Hiroshi, SMIEJA, Daniela, KIKUCHI, Naoya, HANAUER, Guido, SATOMI, Yoshinori, ZITT, Christof, SCHÄFER, Michaela, ANDO, Tatsuya, HAZAMA, Masatoshi, NIKAM, Sham, OOKAWARA, Mitsugi, MATSUO, Takanori
Year of Publication 19.04.2018
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Year of Publication 19.04.2018
Patent