Role of the ERK pathway in psychostimulant-induced locomotor sensitization
Valjent, Emmanuel, Corvol, Jean-Christophe, Trzaskos, James M, Girault, Jean-Antoine, Hervé, Denis
Published in BMC neuroscience (02.03.2006)
Published in BMC neuroscience (02.03.2006)
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Aggrecan Protects Cartilage Collagen from Proteolytic Cleavage
Pratta, Michael A., Yao, Wenqing, Decicco, Carl, Tortorella, Micky D., Liu, Riu-Qin, Copeland, Robert A., Magolda, Ronald, Newton, Robert C., Trzaskos, James M., Arner, Elizabeth C.
Published in The Journal of biological chemistry (14.11.2003)
Published in The Journal of biological chemistry (14.11.2003)
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Significant Neuroprotection against Ischemic Brain Injury by Inhibition of the MEK1 Protein Kinase in Mice: Exploration of Potential Mechanism Associated with Apoptosis
Wang, Xinkang, Wang, Hugh, Xu, Lin, Rozanski, Dennis J, Sugawara, Taku, Chan, Pak H, Trzaskos, James M, Feuerstein, Giora Z
Published in The Journal of pharmacology and experimental therapeutics (01.01.2003)
Published in The Journal of pharmacology and experimental therapeutics (01.01.2003)
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Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II
Dinchuk, Joseph E, Car, Bruce D, Focht, Richard J, Johnston, Jennifer J, Jaffee, Bruce D, Covington, Maryanne B, Contel, Nancy R, Eng, Vicki M, Collins, Robert J, Czerniak, Philip M, Gorry, Stewart A, Trzaskos, James M
Published in Nature (London) (23.11.1995)
Published in Nature (London) (23.11.1995)
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Inhibition of MAP Kinase Kinase Prevents Cytokine and Prostaglandin E2 Production in Lipopolysaccharide-Stimulated Monocytes
Scherle, Peggy A, Jones, Elizabeth A, Favata, Margaret F, Daulerio, Andrea J, Covington, Maryanne B, Nurnberg, Sherrill A, Magolda, Ronald L, Trzaskos, James M
Published in The Journal of immunology (1950) (15.11.1998)
Published in The Journal of immunology (1950) (15.11.1998)
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Discovery of a small molecule antagonist of the parathyroid hormone receptor by using an N-terminal parathyroid hormone peptide probe
Carter, Percy H, Liu, Rui-Qin, Foster, William R, Tamasi, Joseph A, Tebben, Andrew J, Favata, Margaret, Staal, Ada, Cvijic, Mary Ellen, French, Michele H, Dell, Vanessa, Apanovitch, Donald, Lei, Ming, Zhao, Qihong, Cunningham, Mark, Decicco, Carl P, Trzaskos, James M, Feyen, Jean H.M
Published in Proceedings of the National Academy of Sciences - PNAS (17.04.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (17.04.2007)
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Selective Inhibition of Eosinophil Influx into the Lung by Small Molecule CC Chemokine Receptor 3 Antagonists in Mouse Models of Allergic Inflammation
Das, Anuk M, Vaddi, Krishna G, Solomon, Kimberly A, Krauthauser, Candice, Jiang, Xiaosui, McIntyre, Kim W, Yang, Xiao Xia, Wadman, Eric, Welch, Patricia, Covington, Maryanne, Graden, Danielle, Yeleswaram, Krishnaswamy, Trzaskos, James M, Newton, Robert C, Mandlekar, Sandhya, Ko, Soo S, Carter, Percy H, Davies, Paul
Published in The Journal of pharmacology and experimental therapeutics (01.07.2006)
Published in The Journal of pharmacology and experimental therapeutics (01.07.2006)
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In vivo identification of the mitogen-activated protein kinase cascade as a central pathogenic pathway in experimental mesangioproliferative glomerulonephritis
BOKEMEYER, Dirk, PANEK, Darius, KRAMER, Herbert J, LINDEMANN, Marion, KITAHARA, Masashi, BOOR, Peter, KERJASCHKI, Dontscho, TRZASKOS, James M, FLOEGE, Jürgen, OSTENDORF, Tammo
Published in Journal of the American Society of Nephrology (01.06.2002)
Published in Journal of the American Society of Nephrology (01.06.2002)
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Cyclooxygenase-2 Differentially Directs Uterine Angiogenesis during Implantation in Mice
Matsumoto, Hiromichi, Ma, Wen-Ge, Daikoku, Takiko, Zhao, Xhume, Paria, Bibhash C, Das, Sanjoy K, Trzaskos, James M, Dey, Sudhansu K
Published in The Journal of biological chemistry (09.08.2002)
Published in The Journal of biological chemistry (09.08.2002)
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Multiple Female Reproductive Failures in Cyclooxygenase 2–Deficient Mice
Lim, Hyunjung, Paria, Bibhash C, Das, Sanjoy K, Dinchuk, Joseph E, Langenbach, Robert, Trzaskos, James M, Dey, Sudhansu K
Published in Cell (17.10.1997)
Published in Cell (17.10.1997)
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Beyond U0126. Dianion chemistry leading to the rapid synthesis of a series of potent MEK inhibitors
Wityak, John, Hobbs, Frank W., Gardner, Daniel S., Santella, Joseph B., Petraitis, Joseph J., Sun, Jung-Hui, Favata, Margaret F., Daulerio, Andrea J., Horiuchi, Kurumi Y., Copeland, Robert A., Scherle, Peggy A., Jaffe, Bruce D., Trzaskos, James M., Magolda, Ronald L., Trainor, George L., Duncia, John V.
Published in Bioorganic & medicinal chemistry letters (22.03.2004)
Published in Bioorganic & medicinal chemistry letters (22.03.2004)
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Identification of a Novel Inhibitor of Mitogen-activated Protein Kinase Kinase
Favata, M F, Horiuchi, K Y, Manos, E J, Daulerio, A J, Stradley, D A, Feeser, W S, Van Dyk, D E, Pitts, W J, Earl, R A, Hobbs, F, Copeland, R A, Magolda, R L, Scherle, P A, Trzaskos, J M
Published in The Journal of biological chemistry (17.07.1998)
Published in The Journal of biological chemistry (17.07.1998)
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A High-Throughput Fluorescent Polarization Assay for Nuclear Receptor Binding Utilizing Crude Receptor Extract
Lin, Siqi, Bock, Cindy L., Gardner, Debra B., Webster, Jeffery C., Favata, Margaret F., Trzaskos, James M., Oldenburg, Kevin R.
Published in Analytical biochemistry (01.01.2002)
Published in Analytical biochemistry (01.01.2002)
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A necessity for MAP kinase activation in mammalian spatial learning
Selcher, J C, Atkins, C M, Trzaskos, J M, Paylor, R, Sweatt, J D
Published in Learning & memory (Cold Spring Harbor, N.Y.) (01.09.1999)
Published in Learning & memory (Cold Spring Harbor, N.Y.) (01.09.1999)
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Potent, exceptionally selective, orally bioavailable inhibitors of TNF-alpha Converting Enzyme (TACE): novel 2-substituted-1H-benzo[d]imidazol-1-yl)methyl)benzamide P1' substituents
Ott, Gregory R, Asakawa, Naoyuki, Lu, Zhonghui, Anand, Rajan, Liu, Rui-Qin, Covington, Maryanne B, Vaddi, Krishna, Qian, Mingxin, Newton, Robert C, Christ, David D, Trzaskos, James M, Duan, James J-W
Published in Bioorganic & medicinal chemistry (01.03.2008)
Published in Bioorganic & medicinal chemistry (01.03.2008)
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Journal Article
The MAPK cascade is required for mammalian associative learning
Atkins, Coleen M., Selcher, Joel C., Petraitis, Joseph J., Trzaskos, James M., Sweatt, J. David
Published in Nature neuroscience (01.11.1998)
Published in Nature neuroscience (01.11.1998)
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Long-Term Depression in the Adult Hippocampus In Vivo Involves Activation of Extracellular Signal-Regulated Kinase and Phosphorylation of Elk-1
Thiels, Edda, Kanterewicz, Beatriz I, Norman, Eric D, Trzaskos, James M, Klann, Eric
Published in The Journal of neuroscience (15.03.2002)
Published in The Journal of neuroscience (15.03.2002)
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Inhibition of Mitogen-Activated Protein Kinase Kinase Blocks T Cell Proliferation But Does Not Induce or Prevent Anergy
DeSilva, Dimuthu R, Jones, Elizabeth A, Favata, Margaret F, Jaffee, Bruce D, Magolda, Ronald L, Trzaskos, James M, Scherle, Peggy A
Published in The Journal of immunology (1950) (01.05.1998)
Published in The Journal of immunology (1950) (01.05.1998)
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COX-3: in the wrong frame in mind
Dinchuk, Joseph E., Liu, Richard Q., Trzaskos, James M.
Published in Immunology letters (03.03.2003)
Published in Immunology letters (03.03.2003)
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Discovery of β-benzamido hydroxamic acids as potent, selective, and orally bioavailable TACE inhibitors
Duan, James J.-W., Chen, Lihua, Lu, Zhonghui, Xue, Chu-Biao, Liu, Rui-Qin, Covington, Maryanne B., Qian, Mingxin, Wasserman, Zelda R., Vaddi, Krishna, Christ, David D., Trzaskos, James M., Newton, Robert C., Decicco, Carl P.
Published in Bioorganic & medicinal chemistry (2008)
Published in Bioorganic & medicinal chemistry (2008)
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