CCR5 receptor antagonists in preclinical to phase II clinical development for treatment of HIV
Kim, Michelle B, Giesler, Kyle E, Tahirovic, Yesim A, Truax, Valarie M, Liotta, Dennis C, Wilson, Lawrence J
Published in Expert opinion on investigational drugs (01.12.2016)
Published in Expert opinion on investigational drugs (01.12.2016)
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Journal Article
Design, Synthesis, and Pharmacological Evaluation of Second-Generation Tetrahydroisoquinoline-Based CXCR4 Antagonists with Favorable ADME Properties
Nguyen, Huy H., Kim, Michelle B., Wilson, Robert J., Butch, Christopher J., Kuo, Katie M., Miller, Eric J., Tahirovic, Yesim A., Jecs, Edgars, Truax, Valarie M., Wang, Tao, Sum, Chi S., Cvijic, Mary E., Schroeder, Gretchen M., Wilson, Lawrence J., Liotta, Dennis C.
Published in Journal of medicinal chemistry (23.08.2018)
Published in Journal of medicinal chemistry (23.08.2018)
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Journal Article
Discovery of Tetrahydroisoquinoline-Containing CXCR4 Antagonists with Improved in Vitro ADMET Properties
Miller, Eric J, Jecs, Edgars, Truax, Valarie M, Katzman, Brooke M, Tahirovic, Yesim A, Wilson, Robert J, Kuo, Katie M, Kim, Michelle B, Nguyen, Huy H, Saindane, Manohar T, Zhao, Huanyu, Wang, Tao, Sum, Chi S, Cvijic, Mary E, Schroeder, Gretchen M, Wilson, Lawrence J, Liotta, Dennis C
Published in Journal of medicinal chemistry (08.02.2018)
Published in Journal of medicinal chemistry (08.02.2018)
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Journal Article
Amino-Heterocycle Tetrahydroisoquinoline CXCR4 Antagonists with Improved ADME Profiles via Late-Stage Buchwald Couplings
Nguyen, Huy H, Tahirovic, Yesim A, Truax, Valarie M, Wilson, Robert J, Jecs, Edgars, Miller, Eric J, Kim, Michelle B, Akins, Nicholas S, Xu, Lingjie, Jiang, Yi, Wang, Tao, Sum, Chi S, Cvijic, Mary E, Schroeder, Gretchen M, Wilson, Lawrence J, Liotta, Dennis C
Published in ACS medicinal chemistry letters (14.10.2021)
Published in ACS medicinal chemistry letters (14.10.2021)
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Journal Article
Discovery of Tetrahydroisoquinoline-Based CXCR4 Antagonists
Truax, Valarie M, Zhao, Huanyu, Katzman, Brooke M, Prosser, Anthony R, Alcaraz, Ana A, Saindane, Manohar T, Howard, Randy B, Culver, Deborah, Arrendale, Richard F, Gruddanti, Prahbakar R, Evers, Taylor J, Natchus, Michael G, Snyder, James P, Liotta, Dennis C, Wilson, Lawrence J
Published in ACS medicinal chemistry letters (14.11.2013)
Published in ACS medicinal chemistry letters (14.11.2013)
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Journal Article
Synthesis of Novel Tetrahydroisoquinoline CXCR4 Antagonists with Rigidified Side-Chains
Jecs, Edgars, Miller, Eric J, Wilson, Robert J, Nguyen, Huy H, Tahirovic, Yesim A, Katzman, Brook M, Truax, Valarie M, Kim, Michelle B, Kuo, Katie M, Wang, Tao, Sum, Chi S, Cvijic, Mary E, Schroeder, Gretchen M, Wilson, Lawrence J, Liotta, Dennis C
Published in ACS medicinal chemistry letters (08.02.2018)
Published in ACS medicinal chemistry letters (08.02.2018)
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Journal Article
Discovery of N‑Alkyl Piperazine Side Chain Based CXCR4 Antagonists with Improved Drug-like Properties
Tahirovic, Yesim A, Truax, Valarie M, Wilson, Robert J, Jecs, Edgars, Nguyen, Huy H, Miller, Eric J, Kim, Michelle B, Kuo, Katie M, Wang, Tao, Sum, Chi S, Cvijic, Mary E, Schroeder, Gretchen M, Wilson, Lawrence J, Liotta, Dennis C
Published in ACS medicinal chemistry letters (10.05.2018)
Published in ACS medicinal chemistry letters (10.05.2018)
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Journal Article
Synthesis and SAR of 1,2,3,4-Tetrahydroisoquinoline-Based CXCR4 Antagonists
Wilson, Robert J, Jecs, Edgars, Miller, Eric J, Nguyen, Huy H, Tahirovic, Yesim A, Truax, Valarie M, Kim, Michelle B, Kuo, Katie M, Wang, Tao, Sum, Chi Shing, Cvijic, Mary E, Paiva, Anthony A, Schroeder, Gretchen M, Wilson, Lawrence J, Liotta, Dennis C
Published in ACS medicinal chemistry letters (11.01.2018)
Published in ACS medicinal chemistry letters (11.01.2018)
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Journal Article
Synthesis and Evaluation of Novel Tetrahydronaphthyridine CXCR4 Antagonists with Improved Drug-like Profiles
Jecs, Edgars, Tahirovic, Yesim A, Wilson, Robert J, Miller, Eric J, Kim, Michelle, Truax, Valarie, Nguyen, Huy H, Akins, Nicholas S, Saindane, Manohar, Wang, Tao, Sum, Chi S, Cvijic, Mary E, Schroeder, Gretchen M, Burton, Samantha L, Derdeyn, Cynthia A, Xu, Lingjie, Jiang, Yi, Wilson, Lawrence J, Liotta, Dennis C
Published in Journal of medicinal chemistry (10.03.2022)
Published in Journal of medicinal chemistry (10.03.2022)
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Journal Article
Small molecule CXCR4 antagonists block the HIV-1 Nef/CXCR4 axis and selectively initiate the apoptotic program in breast cancer cells
Huang, Ming-Bo, Giesler, Kyle E, Katzman, Brooke M, Prosser, Anthony R, Truax, Valarie, Liotta, Dennis C, Wilson, Lawrence J, Bond, Vincent C
Published in Oncotarget (30.03.2018)
Published in Oncotarget (30.03.2018)
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Journal Article
Chemokine CXCR4 Receptor Modulators and Uses Related Thereto
Jecs, Edgars, Kim, Michelle Bora, Nguyen, Huy Hoang, Wilson, Robert James, Miller, Eric, Liotta, Dennis C, Wilson, Lawrence, Truax, Valarie, Altas Tahirovic, Yesim
Year of Publication 26.09.2024
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Year of Publication 26.09.2024
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