Activation of GPR40 induces hypothalamic neurogenesis through p38- and BDNF-dependent mechanisms
Engel, Daiane F., Bobbo, Vanessa C. D., Solon, Carina S., Nogueira, Guilherme A., Moura-Assis, Alexandre, Mendes, Natalia F., Zanesco, Ariane M., Papangelis, Athanasios, Ulven, Trond, Velloso, Licio A.
Published in Scientific reports (06.07.2020)
Published in Scientific reports (06.07.2020)
Get full text
Journal Article
Non-equivalence of Key Positively Charged Residues of the Free Fatty Acid 2 Receptor in the Recognition and Function of Agonist Versus Antagonist Ligands
Sergeev, Eugenia, Hansen, Anders Højgaard, Pandey, Sunil K., MacKenzie, Amanda E., Hudson, Brian D., Ulven, Trond, Milligan, Graeme
Published in The Journal of biological chemistry (01.01.2016)
Published in The Journal of biological chemistry (01.01.2016)
Get full text
Journal Article
Fatty acid 16:4(n‐3) stimulates a GPR120‐induced signaling cascade in splenic macrophages to promote chemotherapy resistance
Houthuijzen, Julia M., Oosterom, Ilse, Hudson, Brian D., Hirasawa, Akira, Daenen, Laura G. M., McLean, Chelsea M., Hansen, Steffen V. F., Jaarsveld, Marijn T. M., Peeper, Daniel S., Sadatmand, Sahar Jafari, Roodhart, Jeanine M. L., Lest, Chris H. A., Ulven, Trond, Ishihara, Kenji, Milligan, Graeme, Voest, Emile E.
Published in The FASEB journal (01.05.2017)
Published in The FASEB journal (01.05.2017)
Get full text
Journal Article
Acute effects of delayed-release hydrolyzed pine nut oil on glucose tolerance, incretins, ghrelin and appetite in healthy humans
Sørensen, Karina V., Korfitzen, Svend S., Kaspersen, Mads H., Ulven, Elisabeth Rexen, Ekberg, Jeppe H., Bauer-Brandl, Annette, Ulven, Trond, Højlund, Kurt
Published in Clinical nutrition (Edinburgh, Scotland) (01.04.2021)
Published in Clinical nutrition (Edinburgh, Scotland) (01.04.2021)
Get full text
Journal Article
The Two Formyl Peptide Receptors Differently Regulate GPR84-Mediated Neutrophil NADPH Oxidase Activity
Mårtensson, Jonas, Sundqvist, Martina, Manandhar, Asmita, Ieremias, Loukas, Zhang, Linjie, Ulven, Trond, Xie, Xin, Björkman, Lena, Forsman, Huamei
Published in Journal of innate immunity (01.09.2021)
Published in Journal of innate immunity (01.09.2021)
Get full text
Journal Article
Chemically engineering ligand selectivity at the free fatty acid receptor 2 based on pharmacological variation between species orthologs
Hudson, Brian D., Christiansen, Elisabeth, Tikhonova, Irina G., Grundmann, Manuel, Kostenis, Evi, Adams, David R., Ulven, Trond, Milligan, Graeme
Published in The FASEB journal (01.12.2012)
Published in The FASEB journal (01.12.2012)
Get full text
Journal Article
Effects of Delayed-Release Olive Oil and Hydrolyzed Pine Nut Oil on Glucose Tolerance, Incretin Secretion and Appetite in Humans
Sørensen, Karina V., Kaspersen, Mads H., Ekberg, Jeppe H., Bauer-Brandl, Annette, Ulven, Trond, Højlund, Kurt
Published in Nutrients (27.09.2021)
Published in Nutrients (27.09.2021)
Get full text
Journal Article
Treatment of type 2 diabetes by free Fatty Acid receptor agonists
Watterson, Kenneth R, Hudson, Brian D, Ulven, Trond, Milligan, Graeme
Published in Frontiers in endocrinology (Lausanne) (01.01.2014)
Published in Frontiers in endocrinology (Lausanne) (01.01.2014)
Get full text
Journal Article
Probe-Dependent Negative Allosteric Modulators of the Long-Chain Free Fatty Acid Receptor FFA4
Watterson, Kenneth R, Hansen, Steffen V F, Hudson, Brian D, Alvarez-Curto, Elisa, Raihan, Sheikh Zahir, Azevedo, Carlos M G, Martin, Gabriel, Dunlop, Julia, Yarwood, Stephen J, Ulven, Trond, Milligan, Graeme
Published in Molecular pharmacology (01.06.2017)
Published in Molecular pharmacology (01.06.2017)
Get full text
Journal Article
Reevaluation of Fatty Acid Receptor 1 as a Drug Target for the Stimulation of Insulin Secretion in Humans
WAGNER, Robert, KAISER, Gabriele, FRITSCHE, Andreas, HÄRING, Hans-Ulrich, ULLRICH, Susanne, GERST, Felicia, CHRISTIANSEN, Elisabeth, DUE-HANSEN, Maria E, GRUNDMANN, Manuel, MACHICAO, Fausto, PETER, Andreas, KOSTENIS, Evi, ULVEN, Trond
Published in Diabetes (New York, N.Y.) (01.06.2013)
Published in Diabetes (New York, N.Y.) (01.06.2013)
Get full text
Journal Article
Identification of galectin-1 and other cellular targets of alpha,beta-unsaturated carbonyl compounds, including dimethylfumarate, by use of click-chemistry probes
Sauerland, Max B., Helm, Christina, Lorentzen, Lasse G., Manandhar, Asmita, Ulven, Trond, Gamon, Luke F., Davies, Michael J.
Published in Redox biology (01.02.2023)
Published in Redox biology (01.02.2023)
Get full text
Journal Article
A single extracellular amino acid in Free Fatty Acid Receptor 2 defines antagonist species selectivity and G protein selection bias
Sergeev, Eugenia, Hansen, Anders Højgaard, Bolognini, Daniele, Kawakami, Kouki, Kishi, Takayuki, Aoki, Junken, Ulven, Trond, Inoue, Asuka, Hudson, Brian D., Milligan, Graeme
Published in Scientific reports (23.10.2017)
Published in Scientific reports (23.10.2017)
Get full text
Journal Article
The therapeutic potential of allosteric ligands for free fatty acid sensitive GPCRs
Hudson, Brian D, Ulven, Trond, Milligan, Graeme
Published in Current topics in medicinal chemistry (01.01.2013)
Published in Current topics in medicinal chemistry (01.01.2013)
Get more information
Journal Article
Antagonism of the prostaglandin D2 receptor CRTH2 attenuates asthma pathology in mouse eosinophilic airway inflammation
Uller, Lena, Mathiesen, Jesper Mosolff, Alenmyr, Lisa, Korsgren, Magnus, Ulven, Trond, Högberg, Thomas, Andersson, Gunnar, Persson, Carl G A, Kostenis, Evi
Published in Respiratory research (28.02.2007)
Published in Respiratory research (28.02.2007)
Get full text
Journal Article
Discovery of Potent and Selective Agonists for the Free Fatty Acid Receptor 1 (FFA1/GPR40), a Potential Target for the Treatment of Type II Diabetes
Christiansen, Elisabeth, Urban, Christian, Merten, Nicole, Liebscher, Kathrin, Karlsen, Kasper K, Hamacher, Alexandra, Spinrath, Andreas, Bond, Andrew D, Drewke, Christel, Ullrich, Susanne, Kassack, Matthias U, Kostenis, Evi, Ulven, Trond
Published in Journal of medicinal chemistry (27.11.2008)
Published in Journal of medicinal chemistry (27.11.2008)
Get full text
Journal Article
Extracellular loop 2 of the free fatty acid receptor 2 mediates allosterism of a phenylacetamide ago-allosteric modulator
Smith, Nicola J, Ward, Richard J, Stoddart, Leigh A, Hudson, Brian D, Kostenis, Evi, Ulven, Trond, Morris, Joanne C, Tränkle, Christian, Tikhonova, Irina G, Adams, David R, Milligan, Graeme
Published in Molecular pharmacology (01.07.2011)
Published in Molecular pharmacology (01.07.2011)
Get full text
Journal Article
Hypothalamic free fatty acid receptor-1 regulates whole-body energy balance
Dragano, Nathalia R V, Milbank, Edward, Haddad-Tóvolli, Roberta, Garrido-Gil, Pablo, Nóvoa, Eva, Fondevilla, Marcos F, Capelli, Valentina, Zanesco, Ariane Maria, Solon, Carina, Morari, Joseane, Pires, Leticia, Estevez-Salguero, Ánxela, Beiroa, Daniel, González-García, Ismael, Barca-Mayo, Olga, Diéguez, Carlos, Nogueiras, Ruben, Labandeira-García, José L, Ulven, Elisabeth Rexen, Ulven, Trond, Claret, Marc, Velloso, Licio A, Lopez, Miguel
Published in Molecular metabolism (Germany) (01.01.2024)
Published in Molecular metabolism (Germany) (01.01.2024)
Get full text
Journal Article
Autocrine negative feedback regulation of lipolysis through sensing of NEFAs by FFAR4/GPR120 in WAT
Husted, Anna Sofie, Ekberg, Jeppe H., Tripp, Emma, Nissen, Tinne A.D., Meijnikman, Stijn, O'Brien, Shannon L., Ulven, Trond, Acherman, Yair, Bruin, Sjoerd C., Nieuwdorp, Max, Gerhart-Hines, Zach, Calebiro, Davide, Dragsted, Lars O., Schwartz, Thue W.
Published in Molecular metabolism (Germany) (01.12.2020)
Published in Molecular metabolism (Germany) (01.12.2020)
Get full text
Journal Article