Population pharmacokinetics of piperacillin and tazobactam in critically ill patients undergoing continuous renal replacement therapy: application to pharmacokinetic/pharmacodynamic analysis
Asín-Prieto, Eduardo, Rodríguez-Gascón, Alicia, Trocóniz, Iñaki F, Soraluce, Amaia, Maynar, Javier, Sánchez-Izquierdo, José Ángel, Isla, Arantxazu
Published in Journal of antimicrobial chemotherapy (01.01.2014)
Published in Journal of antimicrobial chemotherapy (01.01.2014)
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Gene Therapy: A Pharmacokinetic/Pharmacodynamic Modelling Overview
Parra-Guillén, Zinnia P, González-Aseguinolaza, Gloria, Berraondo, Pedro, Trocóniz, Iñaki F
Published in Pharmaceutical research (01.08.2010)
Published in Pharmaceutical research (01.08.2010)
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Semi-mechanistic population pharmacokinetic/pharmacodynamic model for neutropenia following therapy with the Plk-1 inhibitor BI 2536 and its application in clinical development
Soto, Elena, Staab, Alexander, Tillmann, Christiane, Trommeshauser, Dirk, Fritsch, Holger, Munzert, Gerd, Trocóniz, Iñaki F
Published in Cancer chemotherapy and pharmacology (01.09.2010)
Published in Cancer chemotherapy and pharmacology (01.09.2010)
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IMI2-PainCare-BioPain-RCT2 protocol: a randomized, double-blind, placebo-controlled, crossover, multicenter trial in healthy subjects to investigate the effects of lacosamide, pregabalin, and tapentadol on biomarkers of pain processing observed by non-invasive neurophysiological measurements of human spinal cord and brainstem activity
Leone, Caterina, Di Stefano, Giulia, Di Pietro, Giuseppe, Bloms-Funke, Petra, Boesl, Irmgard, Caspani, Ombretta, Chapman, Sonya C, Finnerup, Nanna Brix, Garcia-Larrea, Luis, Li, Tom, Goetz, Marcus, Mouraux, André, Pelz, Bernhard, Pogatzki-Zahn, Esther, Schilder, Andreas, Schnetter, Erik, Schubart, Karin, Tracey, Irene, Troconiz, Inaki F, Van Niel, Hans, Hernandez, Jose Miguel Vela, Vincent, Katy, Vollert, Jan, Wanigasekera, Vishvarani, Wittayer, Matthias, Phillips, Keith G, Truini, Andrea, Treede, Rolf-Detlef
Published in Current controlled trials in cardiovascular medicine (05.09.2022)
Published in Current controlled trials in cardiovascular medicine (05.09.2022)
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Predictive ability of a semi-mechanistic model for neutropenia in the development of novel anti-cancer agents: two case studies
Soto, Elena, Keizer, Ron J., Trocóniz, Iñaki F., Huitema, Alwin D. R., Beijnen, Jos H., Schellens, Jan H. M., Wanders, Jantien, Cendrós, Josep María, Obach, Rosendo, Peraire, Concepción, Friberg, Lena E., Karlsson, Mats O.
Published in Investigational new drugs (01.10.2011)
Published in Investigational new drugs (01.10.2011)
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Disentangling Anti‐Tumor Response of Immunotherapy Combinations: A Physiologically Based Framework for V937 Oncolytic Virus and Pembrolizumab
Sancho‐Araiz, Aymara, Parra‐Guillen, Zinnia P., Troconiz, Iñaki F., Freshwater, Tomoko
Published in Clinical pharmacology and therapeutics (01.11.2024)
Published in Clinical pharmacology and therapeutics (01.11.2024)
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How to use meropenem in pediatric patients undergoing CKRT? Integrated meropenem pharmacokinetic model for critically ill children
Butragueño-Laiseca, Laura, Troconiz, Iñaki F, Grau, Santiago, Campillo, Nuria, Padilla, Belén, Fernández, Sarah Nicole, Slöcker, María, Herrera, Laura, Santiago, María José
Published in Antimicrobial agents and chemotherapy (24.04.2024)
Published in Antimicrobial agents and chemotherapy (24.04.2024)
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Mechanism-Based Modeling of Perioperative Variations in Hemoglobin Concentration in Patients Undergoing Laparoscopic Surgery
Jaramillo, Sebastian, Marco-Ariño, Nicolás, Montane-Muntane, Mar, Blasi, Annabel, Navarro-Ripoll, Ricard, de Peray-Bruel, Claudia, Vila-Cullell, Isabel, Gambús, Pedro L, Troconiz, Iñaki F
Published in Anesthesia and analgesia (01.01.2024)
Published in Anesthesia and analgesia (01.01.2024)
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Dual activity of PD-L1 targeted Doxorubicin immunoliposomes promoted an enhanced efficacy of the antitumor immune response in melanoma murine model
Merino, María, Lozano, Teresa, Casares, Noelia, Lana, Hugo, Troconiz, Iñaki F, Ten Hagen, Timo L M, Kochan, Grazyna, Berraondo, Pedro, Zalba, Sara, Garrido, María J
Published in Journal of nanobiotechnology (13.04.2021)
Published in Journal of nanobiotechnology (13.04.2021)
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Assessment of Clinical Response to V937 Oncolytic Virus After Intravenous or Intratumoral Administration Using Physiologically-Based Modeling
Parra-Guillen, Zinnia P, Sancho-Araiz, Aymara, Mayawala, Kapil, Zalba, Sara, Garrido, Maria J, de Alwis, Dinesh, Troconiz, Iñaki F, Freshwater, Tomoko
Published in Clinical pharmacology and therapeutics (01.09.2023)
Published in Clinical pharmacology and therapeutics (01.09.2023)
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Model-Informed Dose Selection for Xentuzumab, a Dual Insulin-Like Growth Factor-I/II-Neutralizing Antibody
Parra-Guillen, Zinnia P, Schmid, Ulrike, Janda, Alvaro, Freiwald, Matthias, Troconiz, Iñaki F
Published in Clinical pharmacology and therapeutics (01.03.2020)
Published in Clinical pharmacology and therapeutics (01.03.2020)
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Comparison of two pharmacokinetic–pharmacodynamic models of rocuronium bromide during profound neuromuscular block: analysis of estimated and measured post-tetanic count effect
Couto, Mafalda, Vide, Sérgio, Marco-Ariño, Nicolás, Troconiz, Iñaki F., Esteves, Simão, Nunes, Catarina S., Amorim, Pedro, Mendes, Joaquim
Published in British journal of anaesthesia : BJA (01.03.2022)
Published in British journal of anaesthesia : BJA (01.03.2022)
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A new immune-nanoplatform for promoting adaptive antitumor immune response
Merino, María, Contreras, Ana, Casares, Noelia, Troconiz, Iñaki F., ten Hagen, Timo LM, Berraondo, Pedro, Zalba, Sara, Garrido, María J
Published in Nanomedicine (01.04.2019)
Published in Nanomedicine (01.04.2019)
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Population pharmacokinetics of sublingually administered tacrolimus in infants and young children with liver transplantation
Riva, Natalia, Ibarra, Manuel, Parra‐Guillen, Zinnia P., Galván, Maria Eugenia, Pérez, Erika, Trezeguet Renatti, Guido, Cáceres Guido, Paulo, Lopez, Clarisa, Licciardone, Nieves, Halac, Esteban, Dip, Marcelo, Cruz, Alejandro, Imventarza, Oscar, Buamscha, Daniel, Troconiz, Iñaki F., Schaiquevich, Paula
Published in British journal of clinical pharmacology (01.03.2023)
Published in British journal of clinical pharmacology (01.03.2023)
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Mechanistic Modeling of a Novel Oncolytic Virus, V937, to Describe Viral Kinetic and Dynamic Processes Following Intratumoral and Intravenous Administration
Parra-Guillen, Zinnia P., Freshwater, Tomoko, Cao, Youfang, Mayawala, Kapil, Zalba, Sara, Garrido, Maria J., de Alwis, Dinesh, Troconiz, Iñaki F.
Published in Frontiers in pharmacology (23.07.2021)
Published in Frontiers in pharmacology (23.07.2021)
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Characterizing Gemcitabine Effects Administered as Single Agent or Combined with Carboplatin in Mice Pancreatic and Ovarian Cancer Xenografts: A Semimechanistic Pharmacokinetic/Pharmacodynamics Tumor Growth-Response Model
Garcia-Cremades, Maria, Pitou, Celine, Iversen, Philip W, Troconiz, Iñaki F
Published in The Journal of pharmacology and experimental therapeutics (01.03.2017)
Published in The Journal of pharmacology and experimental therapeutics (01.03.2017)
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