Model-Based Bioequivalence Analysis to Assess and Predict the Relative Bioavailability of Valproic Acid Formulations
Schiavo, Alejandra, Fagiolino, Pietro, Vázquez, Marta, Tróconiz, Iñaki, Ibarra, Manuel
Published in European journal of drug metabolism and pharmacokinetics (01.07.2024)
Published in European journal of drug metabolism and pharmacokinetics (01.07.2024)
Get full text
Journal Article
Population pharmacokinetics of piperacillin and tazobactam in critically ill patients undergoing continuous renal replacement therapy: application to pharmacokinetic/pharmacodynamic analysis
Asín-Prieto, Eduardo, Rodríguez-Gascón, Alicia, Trocóniz, Iñaki F, Soraluce, Amaia, Maynar, Javier, Sánchez-Izquierdo, José Ángel, Isla, Arantxazu
Published in Journal of antimicrobial chemotherapy (01.01.2014)
Published in Journal of antimicrobial chemotherapy (01.01.2014)
Get full text
Journal Article
Gene Therapy: A Pharmacokinetic/Pharmacodynamic Modelling Overview
Parra-Guillén, Zinnia P, González-Aseguinolaza, Gloria, Berraondo, Pedro, Trocóniz, Iñaki F
Published in Pharmaceutical research (01.08.2010)
Published in Pharmaceutical research (01.08.2010)
Get full text
Journal Article
Semi-mechanistic population pharmacokinetic/pharmacodynamic model for neutropenia following therapy with the Plk-1 inhibitor BI 2536 and its application in clinical development
Soto, Elena, Staab, Alexander, Tillmann, Christiane, Trommeshauser, Dirk, Fritsch, Holger, Munzert, Gerd, Trocóniz, Iñaki F
Published in Cancer chemotherapy and pharmacology (01.09.2010)
Published in Cancer chemotherapy and pharmacology (01.09.2010)
Get full text
Journal Article
Kidney and liver distribution of ochratoxin A in male and female F344 rats
Vettorazzi, Ariane, de Trocóniz, Iñaki Fernández, González-Peñas, Elena, Arbillaga, Leire, Corcuera, Laura-Ana, Gil, Ana Gloria, de Cerain, Adela López
Published in Food and chemical toxicology (01.09.2011)
Published in Food and chemical toxicology (01.09.2011)
Get full text
Journal Article
Semi-Mechanistic Pharmacokinetic Modeling of Lipid Core Nanocapsules: Understanding Quetiapine Plasma and Brain Disposition in a Neurodevelopmental Animal Model of Schizophrenia
Carreño, Fernando, Helfer, Victória Eteges, Staudt, Keli Jaqueline, Olivo, Laura Bem, Paese, Karina, Meyer, Fabíola Schons, Herrmann, Ana Paula, Guterres, Sílvia Stanisçuaski, Kuze Rates, Stela Mari, Trocóniz, Iñaki, Dalla Costa, Teresa
Published in The Journal of pharmacology and experimental therapeutics (01.10.2020)
Published in The Journal of pharmacology and experimental therapeutics (01.10.2020)
Get full text
Journal Article
IMI2-PainCare-BioPain-RCT2 protocol: a randomized, double-blind, placebo-controlled, crossover, multicenter trial in healthy subjects to investigate the effects of lacosamide, pregabalin, and tapentadol on biomarkers of pain processing observed by non-invasive neurophysiological measurements of human spinal cord and brainstem activity
Leone, Caterina, Di Stefano, Giulia, Di Pietro, Giuseppe, Bloms-Funke, Petra, Boesl, Irmgard, Caspani, Ombretta, Chapman, Sonya C, Finnerup, Nanna Brix, Garcia-Larrea, Luis, Li, Tom, Goetz, Marcus, Mouraux, André, Pelz, Bernhard, Pogatzki-Zahn, Esther, Schilder, Andreas, Schnetter, Erik, Schubart, Karin, Tracey, Irene, Troconiz, Inaki F, Van Niel, Hans, Hernandez, Jose Miguel Vela, Vincent, Katy, Vollert, Jan, Wanigasekera, Vishvarani, Wittayer, Matthias, Phillips, Keith G, Truini, Andrea, Treede, Rolf-Detlef
Published in Current controlled trials in cardiovascular medicine (05.09.2022)
Published in Current controlled trials in cardiovascular medicine (05.09.2022)
Get full text
Journal Article
Model‐Based Reverse Translation Between Veterinary and Human Medicine: The One Health Initiative
Schneider, Benjamin, Balbas‐Martinez, Violeta, Jergens, Albert E., Troconiz, Inaki F., Allenspach, Karin, Mochel, Jonathan P.
Published in CPT: pharmacometrics and systems pharmacology (01.02.2018)
Published in CPT: pharmacometrics and systems pharmacology (01.02.2018)
Get full text
Journal Article
A precision medicine test predicts clinical response after idarubicin and cytarabine induction therapy in AML patients
Martínez-Cuadrón, David, Gil, Cristina, Serrano, Josefina, Rodríguez, Gabriela, Pérez-Oteyza, Jaime, García-Boyero, Raimundo, Jiménez-Bravo, Santiago, Vives, Susana, Vidriales, María Belén, Lavilla, Esperanza, Pérez-Simón, José A., Tormo, Mar, Colorado, Mercedes, Bergua, Juan, López, Juan A., Herrera, Pilar, Hernández-Campo, Pilar, Gorrochategui, Julián, Primo, Daniel, Rojas, Jose Luis, Villoria, Jesús, Moscardó, Federico, Troconiz, Iñaki, Linares Gómez, María, Martínez-López, Joaquín, Ballesteros, Joan, Sanz, Miguel, Montesinos, Pau
Published in Leukemia research (01.01.2019)
Published in Leukemia research (01.01.2019)
Get full text
Journal Article
Predictive ability of a semi-mechanistic model for neutropenia in the development of novel anti-cancer agents: two case studies
Soto, Elena, Keizer, Ron J., Trocóniz, Iñaki F., Huitema, Alwin D. R., Beijnen, Jos H., Schellens, Jan H. M., Wanders, Jantien, Cendrós, Josep María, Obach, Rosendo, Peraire, Concepción, Friberg, Lena E., Karlsson, Mats O.
Published in Investigational new drugs (01.10.2011)
Published in Investigational new drugs (01.10.2011)
Get full text
Journal Article
Disentangling Anti-Tumor Response of Immunotherapy Combinations: A Physiologically Based Framework for V937 Oncolytic Virus and Pembrolizumab
Sancho-Araiz, Aymara, Parra-Guillen, Zinnia P, Troconiz, Iñaki F, Freshwater, Tomoko
Published in Clinical pharmacology and therapeutics (22.07.2024)
Published in Clinical pharmacology and therapeutics (22.07.2024)
Get more information
Journal Article
How to use meropenem in pediatric patients undergoing CKRT? Integrated meropenem pharmacokinetic model for critically ill children
Butragueño-Laiseca, Laura, Troconiz, Iñaki F, Grau, Santiago, Campillo, Nuria, Padilla, Belén, Fernández, Sarah Nicole, Slöcker, María, Herrera, Laura, Santiago, María José
Published in Antimicrobial agents and chemotherapy (24.04.2024)
Published in Antimicrobial agents and chemotherapy (24.04.2024)
Get full text
Journal Article
Mechanism-Based Modeling of Perioperative Variations in Hemoglobin Concentration in Patients Undergoing Laparoscopic Surgery
Jaramillo, Sebastian, Marco-Ariño, Nicolás, Montane-Muntane, Mar, Blasi, Annabel, Navarro-Ripoll, Ricard, de Peray-Bruel, Claudia, Vila-Cullell, Isabel, Gambús, Pedro L, Troconiz, Iñaki F
Published in Anesthesia and analgesia (01.01.2024)
Published in Anesthesia and analgesia (01.01.2024)
Get more information
Journal Article
Assessment of Clinical Response to V937 Oncolytic Virus After Intravenous or Intratumoral Administration Using Physiologically-Based Modeling
Parra-Guillen, Zinnia P, Sancho-Araiz, Aymara, Mayawala, Kapil, Zalba, Sara, Garrido, Maria J, de Alwis, Dinesh, Troconiz, Iñaki F, Freshwater, Tomoko
Published in Clinical pharmacology and therapeutics (01.09.2023)
Published in Clinical pharmacology and therapeutics (01.09.2023)
Get more information
Journal Article
Model-Informed Dose Selection for Xentuzumab, a Dual Insulin-Like Growth Factor-I/II-Neutralizing Antibody
Parra-Guillen, Zinnia P, Schmid, Ulrike, Janda, Alvaro, Freiwald, Matthias, Troconiz, Iñaki F
Published in Clinical pharmacology and therapeutics (01.03.2020)
Published in Clinical pharmacology and therapeutics (01.03.2020)
Get more information
Journal Article
Dual activity of PD-L1 targeted Doxorubicin immunoliposomes promoted an enhanced efficacy of the antitumor immune response in melanoma murine model
Merino, María, Lozano, Teresa, Casares, Noelia, Lana, Hugo, Troconiz, Iñaki F, Ten Hagen, Timo L M, Kochan, Grazyna, Berraondo, Pedro, Zalba, Sara, Garrido, María J
Published in Journal of nanobiotechnology (13.04.2021)
Published in Journal of nanobiotechnology (13.04.2021)
Get full text
Journal Article
Comparison of two pharmacokinetic–pharmacodynamic models of rocuronium bromide during profound neuromuscular block: analysis of estimated and measured post-tetanic count effect
Couto, Mafalda, Vide, Sérgio, Marco-Ariño, Nicolás, Troconiz, Iñaki F., Esteves, Simão, Nunes, Catarina S., Amorim, Pedro, Mendes, Joaquim
Published in British journal of anaesthesia : BJA (01.03.2022)
Published in British journal of anaesthesia : BJA (01.03.2022)
Get full text
Journal Article