Search Results - "TRIVEDI, BHARAT K" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Hepatoselectivity of statins: Design and synthesis of 4-sulfamoyl pyrroles as HMG-CoA reductase inhibitors

Hepatoselectivity of statins: Design and synthesis of 4-sulfamoyl pyrroles as HMG-CoA reductase inhibitors

by Park, William K.C., Kennedy, Robert M., Larsen, Scott D., Miller, Steve, Roth, Bruce D., Song, Yuntao, Steinbaugh, Bruce A., Sun, Kevin, Tait, Bradley D., Kowala, Mark C., Trivedi, Bharat K., Auerbach, Bruce, Askew, Valerie, Dillon, Lisa, Hanselman, Jeffrey C., Lin, Zhiwu, Lu, Gina H., Robertson, Andrew, Sekerke, Catherine
Published in Bioorganic & medicinal chemistry (01.02.2008)

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Design and synthesis of hepatoselective, pyrrole-based HMG-CoA reductase inhibitors

Design and synthesis of hepatoselective, pyrrole-based HMG-CoA reductase inhibitors

by Pfefferkorn, Jeffrey A., Song, Yuntao, Sun, Kuai-Lin, Miller, Steven R., Trivedi, Bharat K., Choi, Chulho, Sorenson, Roderick J., Bratton, Larry D., Unangst, Paul C., Larsen, Scott D., Poel, Toni-Jo, Cheng, Xue-Min, Lee, Chitase, Erasga, Noe, Auerbach, Bruce, Askew, Valerie, Dillon, Lisa, Hanselman, Jeffrey C., Lin, Zhiwu, Lu, Gina, Robertson, Andrew, Olsen, Karl, Mertz, Thomas, Sekerke, Catherine, Pavlovsky, Alexander, Harris, Melissa S., Bainbridge, Graeme, Caspers, Nicole, Chen, Huifen, Eberstadt, Matthias
Published in Bioorganic & medicinal chemistry letters (15.08.2007)

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Synthesis and structure–Activity relationship of 2-amino-3-heteroaryl-quinoxalines as non-peptide, small-Molecule antagonists for interleukin-8 receptor

Synthesis and structure–Activity relationship of 2-amino-3-heteroaryl-quinoxalines as non-peptide, small-Molecule antagonists for interleukin-8 receptor

by Li, Jie Jack, Carson, Kenneth G, Trivedi, Bharat K, Yue, Wen Song, Ye, Qing, Glynn, Roberta A, Miller, Steven R, Connor, David T, Roth, Bruce D, Luly, Jay R, Low, Joseph E, Heilig, David J, Yang, Weixing, Qin, Shixin, Hunt, Stephen
Published in Bioorganic & medicinal chemistry (15.08.2003)

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Discovery of novel hepatoselective HMG-CoA reductase inhibitors for treating hypercholesterolemia: A bench-to-bedside case study on tissue selective drug distribution

Discovery of novel hepatoselective HMG-CoA reductase inhibitors for treating hypercholesterolemia: A bench-to-bedside case study on tissue selective drug distribution

by Pfefferkorn, Jeffrey A., Litchfield, John, Hutchings, Richard, Cheng, Xue-Min, Larsen, Scott D., Auerbach, Bruce, Bush, Mark R., Lee, Chitase, Erasga, Noe, Bowles, Daniel M., Boyles, David C., Lu, Gina, Sekerke, Catherine, Askew, Valerie, Hanselman, Jeffrey C., Dillon, Lisa, Lin, Zhiwu, Robertson, Andrew, Olsen, Karl, Boustany, Carine, Atkinson, Karen, Goosen, Theunis C., Sahasrabudhe, Vaishali, Chupka, Jonathan, Duignan, David B., Feng, Bo, Scialis, Renato, Kimoto, Emi, Bi, Yi-An, Lai, Yurong, El-Kattan, Ayman, Bakker-Arkema, Rebecca, Barclay, Paul, Kindt, Erick, Le, Vu, Mandema, Jaap W., Milad, Mark, Tait, Bradley D., Kennedy, Robert, Trivedi, Bharat K., Kowala, Mark
Published in Bioorganic & medicinal chemistry letters (01.05.2011)

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Discovery of pyrrole-based hepatoselective ligands as potent inhibitors of HMG-CoA reductase

Discovery of pyrrole-based hepatoselective ligands as potent inhibitors of HMG-CoA reductase

by Bratton, Larry D., Auerbach, Bruce, Choi, Chulho, Dillon, Lisa, Hanselman, Jeffrey C., Larsen, Scott D., Lu, Gina, Olsen, Karl, Pfefferkorn, Jeffrey A., Robertson, Andrew, Sekerke, Catherine, Trivedi, Bharat K., Unangst, Paul C.
Published in Bioorganic & medicinal chemistry (15.08.2007)

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Design and synthesis of novel, conformationally restricted HMG-CoA reductase inhibitors

Design and synthesis of novel, conformationally restricted HMG-CoA reductase inhibitors

by Pfefferkorn, Jeffrey A., Choi, Chulho, Song, Yuntao, Trivedi, Bharat K., Larsen, Scott D., Askew, Valerie, Dillon, Lisa, Hanselman, Jeffrey C., Lin, Zhiwu, Lu, Gina, Robertson, Andrew, Sekerke, Catherine, Auerbach, Bruce, Pavlovsky, Alexander, Harris, Melissa S., Bainbridge, Graeme, Caspers, Nicole
Published in Bioorganic & medicinal chemistry letters (15.08.2007)

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Inhibitors of acyl-CoA:cholesterol acyltransferase. 1. Identification and structure-activity relationships of a novel series of fatty acid anilide hypocholesterolemic agents

Inhibitors of acyl-CoA:cholesterol acyltransferase. 1. Identification and structure-activity relationships of a novel series of fatty acid anilide hypocholesterolemic agents

by Roth, Bruce D, Blankley, C. John, Hoefle, Milton L, Holmes, Ann, Roark, W. Howard, Trivedi, Bharat K, Essenburg, Arnold D, Kieft, Karen A, Krause, Brian R, Stanfield, Richard L
Published in Journal of medicinal chemistry (01.05.1992)

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Inhibitors of acyl-CoA:cholesterol acyltransferase. 4. A novel series of urea ACAT inhibitors as potential hypocholesterolemic agents

Inhibitors of acyl-CoA:cholesterol acyltransferase. 4. A novel series of urea ACAT inhibitors as potential hypocholesterolemic agents

by Trivedi, Bharat K, Holmes, Ann, Stoeber, Terri L, Blankley, C. John, Roark, W. Howard, Picard, Joseph A, Shaw, Mary K, Essenburg, Arnold D, Stanfield, Richard L, Krause, Brian R
Published in Journal of medicinal chemistry (01.10.1993)

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Attenuation of diet‐induced atherosclerosis in rabbits with a highly selective 15‐lipoxygenase inhibitor lacking significant antioxidant properties

Attenuation of diet‐induced atherosclerosis in rabbits with a highly selective 15‐lipoxygenase inhibitor lacking significant antioxidant properties

by Sendobry, Sandra M., Cornicelli, Joseph A., Welch, Kathryn, Bocan, Thomas, Tait, Bradley, Trivedi, Bharat K., Colbry, Norman, Dyer, Richard D., Feinmark, Steven J., Daugherty, Alan
Published in British journal of pharmacology (01.04.1997)

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Novel Nonpeptide CCK-B Antagonists: Design and Development of Quinazolinone Derivatives as Potent, Selective, and Orally Active CCK-B Antagonists

Novel Nonpeptide CCK-B Antagonists: Design and Development of Quinazolinone Derivatives as Potent, Selective, and Orally Active CCK-B Antagonists

by Padia, Janak K, Field, Mark, Hinton, Joanna, Meecham, Ken, Pablo, Julius, Pinnock, Rob, Roth, Bruce D, Singh, Lakhbir, Suman-Chauhan, Nirmala, Trivedi, Bharat K, Webdale, Louise
Published in Journal of medicinal chemistry (26.03.1998)

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Discovery of highly potent and selective benzyloxybenzyl-based peroxisome proliferator-activator receptor (PPAR) δ agonists

Discovery of highly potent and selective benzyloxybenzyl-based peroxisome proliferator-activator receptor (PPAR) δ agonists

by Bratton, Larry D., Filzen, Gary F., Geyer, Andrew, Hoffman, Jennifer K., Lu, Gina, Pulaski, Jim, Trivedi, Bharat K., Unangst, Paul C., Xu, Xiangyang
Published in Bioorganic & medicinal chemistry letters (01.07.2007)

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Inhibitors of acyl-CoA:cholesterol acyltransferase. 5. Identification and structure-activity relationships of novel .beta.-keto amides as hypocholesterolemic agents

Inhibitors of acyl-CoA:cholesterol acyltransferase. 5. Identification and structure-activity relationships of novel .beta.-keto amides as hypocholesterolemic agents

by Augelli-Szafran, Corinne E, Blankley, C. John, Roth, Bruce D, Trivedi, Bharat K, Bousley, Richard F, Essenburg, Arnold D, Hamelehle, Katherine L, Krause, Brian R, Stanfield, Richard L
Published in Journal of medicinal chemistry (01.10.1993)

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Second Generation “Peptoid” CCK-B Receptor Antagonists: Identification and Development of N-(Adamantyloxycarbonyl)-α-methyl-(R)-tryptophan Derivative (CI-1015) with an Improved Pharmacokinetic Profile

by Trivedi, Bharat K, Padia, Janak K, Holmes, Ann, Rose, Steven, Wright, D. Scott, Hinton, Joanna P, Pritchard, Martyn C, Eden, Jon M, Kneen, Clare, Webdale, Louise, Suman-Chauhan, Nirmala, Boden, Phil, Singh, Lakhbir, Field, Mark J, Hill, David
Published in Journal of medicinal chemistry (01.01.1998)

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Inhibitors of Acyl-CoA:Cholesterol Acyltransferase (ACAT). 7. Development of a Series of Substituted N-Phenyl-N'-[(1-phenylcyclopentyl)methyl]ureas with Enhanced Hypocholesterolemic Activity

Inhibitors of Acyl-CoA:Cholesterol Acyltransferase (ACAT). 7. Development of a Series of Substituted N-Phenyl-N'-[(1-phenylcyclopentyl)methyl]ureas with Enhanced Hypocholesterolemic Activity

by Trivedi, Bharat K, Purchase, Terri Stoeber, Holmes, Ann, Augelli-Szafran, Corinne E, Essenburg, Arnold D, Hamelehle, Katherine L, Stanfield, Richard L, Bousley, Richard F, Krause, Brian R
Published in Journal of medicinal chemistry (01.05.1994)

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Inhibitors of acyl-CoA:cholesterol acyltransferase (ACAT). 2. Modification of fatty acid anilide ACAT inhibitors: bioisosteric replacement of the amide bond

Inhibitors of acyl-CoA:cholesterol acyltransferase (ACAT). 2. Modification of fatty acid anilide ACAT inhibitors: bioisosteric replacement of the amide bond

by Roark, W. Howard, Roth, Bruce D, Holmes, Ann, Trivedi, Bharat K, Kieft, Karen A, Essenburg, Arnold D, Krause, Brian R, Stanfield, Richard L
Published in Journal of medicinal chemistry (28.05.1993)

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N6-[2-(3,5-dimethoxyphenyl)-2-(2-methylphenyl)ethyl]adenosine and its uronamide derivatives. Novel adenosine agonists with both high affinity and high selectivity for the adenosine A2 receptor

N6-[2-(3,5-dimethoxyphenyl)-2-(2-methylphenyl)ethyl]adenosine and its uronamide derivatives. Novel adenosine agonists with both high affinity and high selectivity for the adenosine A2 receptor

by Bridges, Alexander J, Bruns, Robert F, Ortwine, Daniel F, Priebe, Steven R, Szotek, Deedee L, Trivedi, Bharat K
Published in Journal of medicinal chemistry (01.07.1988)

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[1,2,4]Triazolo[4,3-a]quinoxalin-4-amines: a new class of A1 receptor selective adenosine antagonists

[1,2,4]Triazolo[4,3-a]quinoxalin-4-amines: a new class of A1 receptor selective adenosine antagonists

by Trivedi, Bharat K, Bruns, Robert F
Published in Journal of medicinal chemistry (01.05.1988)

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C2,N6-Disubstituted adenosines: synthesis and structure-activity relationships

C2,N6-Disubstituted adenosines: synthesis and structure-activity relationships

by Trivedi, Bharat K, Bruns, Robert F
Published in Journal of medicinal chemistry (01.08.1989)

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Development of a practical synthesis of novel, pyrrole-based HMG-CoA reductase inhibitors

Development of a practical synthesis of novel, pyrrole-based HMG-CoA reductase inhibitors

by Pfefferkorn, Jeffrey A., Bowles, Daniel M., Kissel, William, Boyles, David C., Choi, Chulho, Larsen, Scott D., Song, Yuntao, Sun, Kuai-Lin, Miller, Steven R., Trivedi, Bharat K.
Published in Tetrahedron (20.08.2007)

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Stereoselective antitumor properties in the Lewis Lung carcinoma model using bis(morpholinomethyl) derivatives of tricyclic bis(dioxopiperazines)

Stereoselective antitumor properties in the Lewis Lung carcinoma model using bis(morpholinomethyl) derivatives of tricyclic bis(dioxopiperazines)

by Witiak, Donald T, Trivedi, Bharat K, Schmid, Franz A
Published in Journal of medicinal chemistry (01.08.1985)

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