Structure-guided identification of novel VEGFR-2 kinase inhibitors via solution phase parallel synthesis
Tripathy, Rabindranath, Reiboldt, Alyssa, Messina, Patricia A., Iqbal, Mohamed, Singh, Jasbir, Bacon, Edward R., Angeles, Thelma S., Yang, Shi X., Albom, Mark S., Robinson, Candy, Chang, Hong, Ruggeri, Bruce A., Mallamo, John P.
Published in Bioorganic & medicinal chemistry letters (15.04.2006)
Published in Bioorganic & medicinal chemistry letters (15.04.2006)
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Journal Article
Strategies to Mitigate the Bioactivation of 2-Anilino-7-Aryl-Pyrrolo[2,1-f][1,2,4]triazines: Identification of Orally Bioavailable, Efficacious ALK Inhibitors
Mesaros, Eugen F, Thieu, Tho V, Wells, Gregory J, Zificsak, Craig A, Wagner, Jason C, Breslin, Henry J, Tripathy, Rabindranath, Diebold, James L, McHugh, Robert J, Wohler, Ashley T, Quail, Matthew R, Wan, Weihua, Lu, Lihui, Huang, Zeqi, Albom, Mark S, Angeles, Thelma S, Wells-Knecht, Kevin J, Aimone, Lisa D, Cheng, Mangeng, Ator, Mark A, Ott, Gregory R, Dorsey, Bruce D
Published in Journal of medicinal chemistry (12.01.2012)
Published in Journal of medicinal chemistry (12.01.2012)
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Journal Article
Discovery of 7-arylsulfonyl-1,2,3,4, 4a,9a-hexahydro-benzo[4,5]furo[2,3-c]pyridines: Identification of a potent and selective 5-HT6 receptor antagonist showing activity in rat social recognition test
Tripathy, Rabindranath, McHugh, Robert J., Bacon, Edward R., Salvino, Joseph M., Morton, George C., Aimone, Lisa D., Huang, Zeck, Mathiasen, Joanne R., DiCamillo, Amy, Huffman, Mark J., McKenna, Beth A., Kopec, Karla, Lu, Lily D., Qian, Jie, Angeles, Thelma S., Connors, Thomas, Spais, Chrysanthe, Holskin, Beverly, Duzic, Emir, Schaffhauser, Hervé, Rossé, Gerard C.
Published in Bioorganic & medicinal chemistry letters (01.02.2012)
Published in Bioorganic & medicinal chemistry letters (01.02.2012)
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Journal Article
1,2,3-Thiadiazole substituted pyrazolones as potent KDR/VEGFR-2 kinase inhibitors
Tripathy, Rabindranath, Ghose, Arup, Singh, Jasbir, Bacon, Edward R., Angeles, Thelma S., Yang, Shi X., Albom, Mark S., Aimone, Lisa D., Herman, Joseph L., Mallamo, John P.
Published in Bioorganic & medicinal chemistry letters (15.03.2007)
Published in Bioorganic & medicinal chemistry letters (15.03.2007)
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Journal Article
Pyrazolone-based anaplastic lymphoma kinase (ALK) inhibitors: Control of selectivity by a benzyloxy group
Tripathy, Rabindranath, McHugh, Robert J., Ghose, Arup K., Ott, Gregory R., Angeles, Thelma S., Albom, Mark S., Huang, Zeck, Aimone, Lisa D., Cheng, Mangeng, Dorsey, Bruce D.
Published in Bioorganic & medicinal chemistry letters (15.12.2011)
Published in Bioorganic & medicinal chemistry letters (15.12.2011)
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Journal Article
TrkA kinase inhibitors from a library of modified and isosteric Staurosporine aglycone
Tripathy, Rabindranath, Angeles, Thelma S., Yang, Shi X., Mallamo, John P.
Published in Bioorganic & medicinal chemistry (15.06.2008)
Published in Bioorganic & medicinal chemistry (15.06.2008)
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Journal Article
Fused bicyclic derivatives of 2,4-diaminopyrimidine as c-Met inhibitors
Weinberg, Linda R., Albom, Mark S., Angeles, Thelma S., Husten, Jean, Lisko, Joseph G., McHugh, Robert J., Milkiewicz, Karen L., Murthy, Seetha, Ott, Gregory R., Theroff, Jay P., Tripathy, Rabindranath, Underiner, Ted L., Zificsak, Craig A., Dorsey, Bruce D.
Published in Bioorganic & medicinal chemistry letters (01.01.2011)
Published in Bioorganic & medicinal chemistry letters (01.01.2011)
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Journal Article
Discovery of a Potent Inhibitor of Anaplastic Lymphoma Kinase with in Vivo Antitumor Activity
Ott, Gregory R, Tripathy, Rabindranath, Cheng, Mangeng, McHugh, Robert, Anzalone, Andrew V, Underiner, Ted L, Curry, Matthew A, Quail, Matthew R, Lu, Lihui, Wan, Weihua, Angeles, Thelma S, Albom, Mark S, Aimone, Lisa D, Ator, Mark A, Ruggeri, Bruce A, Dorsey, Bruce D
Published in ACS medicinal chemistry letters (09.12.2010)
Published in ACS medicinal chemistry letters (09.12.2010)
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Journal Article
URACIL DERIVATIVES AS AXL AND C-MET KINASE INHIBITORS
TRIPATHY RABINDRANATH, PROUTY CATHERINE P, DANDU REDDEPPAREDDY, JOSEF KURT A, HUDKINS ROBERT L
Year of Publication 17.07.2014
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Year of Publication 17.07.2014
Patent
Calpain inhibitors based on the quiescent affinity label concept: high rates of calpain inactivation with leaving groups derived from N-hydroxy peptide coupling reagents
Tripathy, Rabindranath, Ator, Mark A., Mallamo, John P.
Published in Bioorganic & medicinal chemistry letters (16.10.2000)
Published in Bioorganic & medicinal chemistry letters (16.10.2000)
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Journal Article
Construction of a kinase inhibitor library via parallel synthesis
Tripathy, Rabindranath, Learn, Keith S, Reddy, Dandu R, Iqbal, Mohamed, Singh, Jasbir, Mallamo, John P
Published in Tetrahedron letters (07.01.2002)
Published in Tetrahedron letters (07.01.2002)
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Journal Article
Synthesis and Biological Activity of a Series of Potent Fluoromethyl Ketone Inhibitors of Recombinant Human Calpain I
Chatterjee, Sankar, Ator, Mark A, Bozyczko-Coyne, Donna, Josef, Kurt, Wells, Gregory, Tripathy, Rabindranath, Iqbal, Mohamed, Bihovsky, Ron, Senadhi, Shobha E, Mallya, Satish, O'Kane, Teresa M, McKenna, Beth Ann, Siman, Robert, Mallamo, John P
Published in Journal of medicinal chemistry (07.11.1997)
Published in Journal of medicinal chemistry (07.11.1997)
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Journal Article
Uracil derivatives as AXL and c-MET kinase inhibitors
Prouty, Catherine P, Tripathy, Rabindranath, Dandu, Reddeppa Reddy, Hudkins, Robert L, Josef, Kurt A
Year of Publication 10.07.2018
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Year of Publication 10.07.2018
Patent
d-Amino Acid Containing, High-Affinity Inhibitors of Recombinant Human Calpain I
Chatterjee, Sankar, Gu, Zi-Qiang, Dunn, Derek, Tao, Ming, Josef, Kurt, Tripathy, Rabindranath, Bihovsky, Ron, Senadhi, Shobha E, O'Kane, Teresa M, McKenna, Beth Ann, Mallya, Satish, Ator, Mark A, Bozyczko-Coyne, Donna, Siman, Robert, Mallamo, John P
Published in Journal of medicinal chemistry (16.07.1998)
Published in Journal of medicinal chemistry (16.07.1998)
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Journal Article
Subsite requirements for peptide aldehyde inhibitors of human calpain I
Iqbal, Mohamed, Messina, Patricia A., Freed, Bethany, Das, Manoj, Chatterjee, Sankar, Tripathy, Rabindranath, Ming Tao, Josef, Kurt A., Dembofsky, Bruce, Dunn, Derek, Griffith, Eric, Siman, Robert, Senadhi, Shobha E., Biazzo, William, Bozyczko-Coyne, Donna, Meyer, Sheryl L., Ator, Mark A., Bihovsky, Ron
Published in Bioorganic & medicinal chemistry letters (04.03.1997)
Published in Bioorganic & medicinal chemistry letters (04.03.1997)
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Journal Article
P 2-proline-derived inhibitors of calpain I
Tripathy, Rabindranath, Gu, Zi-Qiang, Dunn, Derek, Senadhi, Shobha E., Ator, Mark A., Chatterjee, Sankar
Published in Bioorganic & medicinal chemistry letters (06.10.1998)
Published in Bioorganic & medicinal chemistry letters (06.10.1998)
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Journal Article