Discovery of a Potent and Orally Active Hedgehog Pathway Antagonist (IPI-926)
Tremblay, Martin R, Lescarbeau, André, Grogan, Michael J, Tan, Eddy, Lin, Grace, Austad, Brian C, Yu, Lin-Chen, Behnke, Mark L, Nair, Somarajan J, Hagel, Margit, White, Kerry, Conley, James, Manna, Joseph D, Alvarez-Diez, Teresa M, Hoyt, Jennifer, Woodward, Caroline N, Sydor, Jens R, Pink, Melissa, MacDougall, John, Campbell, Matthew J, Cushing, Jill, Ferguson, Jeanne, Curtis, Michael S, McGovern, Karen, Read, Margaret A, Palombella, Vito J, Adams, Julian, Castro, Alfredo C
Published in Journal of medicinal chemistry (23.07.2009)
Published in Journal of medicinal chemistry (23.07.2009)
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Discovery of IACS-9779 and IACS-70465 as Potent Inhibitors Targeting Indoleamine 2,3-Dioxygenase 1 (IDO1) Apoenzyme
Hamilton, Matthew M, Mseeh, Faika, McAfoos, Timothy J, Leonard, Paul G, Reyna, Naphtali J, Harris, Angela L, Xu, Alan, Han, Michelle, Soth, Michael J, Czako, Barbara, Theroff, Jay P, Mandal, Pijus K, Burke, Jason P, Virgin-Downey, Brett, Petrocchi, Alessia, Pfaffinger, Dana, Rogers, Norma E, Parker, Connor A, Yu, Simon S, Jiang, Yongying, Krapp, Stephan, Lammens, Alfred, Trevitt, Graham, Tremblay, Martin R, Mikule, Keith, Wilcoxen, Keith, Cross, Jason B, Jones, Philip, Marszalek, Joseph R, Lewis, Richard T
Published in Journal of medicinal chemistry (12.08.2021)
Published in Journal of medicinal chemistry (12.08.2021)
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Discovery of a Selective Phosphoinositide-3-Kinase (PI3K)‑γ Inhibitor (IPI-549) as an Immuno-Oncology Clinical Candidate
Evans, Catherine A, Liu, Tao, Lescarbeau, André, Nair, Somarajan J, Grenier, Louis, Pradeilles, Johan A, Glenadel, Quentin, Tibbitts, Thomas, Rowley, Ann M, DiNitto, Jonathan P, Brophy, Erin E, O’Hearn, Erin L, Ali, Janid A, Winkler, David G, Goldstein, Stanley I, O’Hearn, Patrick, Martin, Christian M, Hoyt, Jennifer G, Soglia, John R, Cheung, Culver, Pink, Melissa M, Proctor, Jennifer L, Palombella, Vito J, Tremblay, Martin R, Castro, Alfredo C
Published in ACS medicinal chemistry letters (08.09.2016)
Published in ACS medicinal chemistry letters (08.09.2016)
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Journal Article
Discovery of IACS-9439, a Potent, Exquisitely Selective, and Orally Bioavailable Inhibitor of CSF1R
Czako, Barbara, Marszalek, Joseph. R, Burke, Jason P, Mandal, Pijus, Leonard, Paul G, Cross, Jason B, Mseeh, Faika, Jiang, Yongying, Chang, Edward Q, Suzuki, Erika, Kovacs, Jeffrey J, Feng, Ningping, Gera, Sonal, Harris, Angela L, Liu, Zhen, Mullinax, Robert A, Pang, Jihai, Parker, Connor A, Spencer, Nakia D, Yu, Simon S, Wu, Qi, Tremblay, Martin R, Mikule, Keith, Wilcoxen, Keith, Heffernan, Timothy P, Draetta, Giulio F, Jones, Philip
Published in Journal of medicinal chemistry (10.09.2020)
Published in Journal of medicinal chemistry (10.09.2020)
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Journal Article
"The genie is out of the bottle": a qualitative study on the impact of COVID-19 on continuing professional development
Soklaridis, Sophie, Shier, Rowen, Zaheer, Rabia, Scully, Michelle, Williams, Betsy, Daniel, Sam J, Sockalingam, Sanjeev, Dang, Linda, Tremblay, Ma
Published in BMC medical education (06.06.2024)
Published in BMC medical education (06.06.2024)
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Journal Article
Nazarov Reactions of Vinyl Cyclopropylamines: An Approach to the Imino-Nazarov Problem
Bonderoff, Sara A, Grant, Tina N, West, F. G, Tremblay, Martin
Published in Organic letters (07.06.2013)
Published in Organic letters (07.06.2013)
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Journal Article
Evaluating the impact of continuing professional development courses on physician behavioral intention: a pre-post study with follow-up at six months
Bakwa Kanyinga, Felly, Gogovor, Amédé, Dofara, Suélène Georgina, Gadio, Souleymane, Tremblay, Martin, Daniel, Sam J., Rivest, Louis-Paul, Légaré, France
Published in BMC medical education (03.09.2023)
Published in BMC medical education (03.09.2023)
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Journal Article
Impact of Educational Activity Formats, Online or In-Person, on the Intention of Medical Specialists to Adopt a Clinical Behaviour: A Comparative Study
Ayivi-Vinz, Gloria, Tremblay, Martin, Gadio, Souleymane, Dofara, Suélène Georgina, Daniel, Sam J, Talbot, Denis, Légaré, France
Published in Journal of CME (01.12.2024)
Published in Journal of CME (01.12.2024)
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Journal Article
Distinct Effects of Two HIV-1 Capsid Assembly Inhibitor Families That Bind the Same Site within the N-Terminal Domain of the Viral CA Protein
LEMKE, Christopher T, TITOLO, Steve, GAGNON, Alexandre, KAWAI, Stephen H, RANCOURT, Jean, TREMBLAY, Martin, YOAKIM, Christiane, SIMONEAU, Bruno, ARCHAMBAULT, Jacques, SUNDQUIST, Wesley I, MASON, Stephen W, VON SCHWEDLER, Uta, GOUDREAU, Nathalie, MERCIER, Jean-François, WARDROP, Elizabeth, FAUCHER, Anne-Marie, COULOMBE, Rene, BANIK, Soma S. R, FADER, Lee
Published in Journal of Virology (01.06.2012)
Published in Journal of Virology (01.06.2012)
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Journal Article
Synthetic Silvestrol Analogues as Potent and Selective Protein Synthesis Inhibitors
Liu, Tao, Nair, Somarajan J, Lescarbeau, André, Belani, Jitendra, Peluso, Stéphane, Conley, James, Tillotson, Bonnie, O’Hearn, Patrick, Smith, Sherri, Slocum, Kelly, West, Kip, Helble, Joseph, Douglas, Mark, Bahadoor, Adilah, Ali, Janid, McGovern, Karen, Fritz, Christian, Palombella, Vito J, Wylie, Andrew, Castro, Alfredo C, Tremblay, Martin R
Published in Journal of medicinal chemistry (25.10.2012)
Published in Journal of medicinal chemistry (25.10.2012)
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Journal Article
New developments in the discovery of small molecule Hedgehog pathway antagonists
Tremblay, Martin R, McGovern, Karen, Read, Margaret A, Castro, Alfredo C
Published in Current opinion in chemical biology (01.06.2010)
Published in Current opinion in chemical biology (01.06.2010)
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Journal Article
2023 ArcticNet Annual Scientific Meeting (ASM2023)
Barnard, Christine, Archambault, Philippe, Dawson, Jackie, Baird, Erica, Demers, Christine, Leroux, Érica, Lizotte, Martine, Macpherson, Julia, Proulx, Guillaume, Sada, Aisha, Tremblay, Martin
Published in Arctic science (01.03.2024)
Published in Arctic science (01.03.2024)
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Journal Article
Semisynthetic Cyclopamine Analogues as Potent and Orally Bioavailable Hedgehog Pathway Antagonists
Tremblay, Martin R, Nevalainen, Marta, Nair, Somarajan J, Porter, James R, Castro, Alfredo C, Behnke, Mark L, Yu, Lin-Chen, Hagel, Margit, White, Kerry, Faia, Kerrie, Grenier, Louis, Campbell, Matthew J, Cushing, Jill, Woodward, Caroline N, Hoyt, Jennifer, Foley, Michael A, Read, Margaret A, Sydor, Jens R, Tong, Jeffrey K, Palombella, Vito J, McGovern, Karen, Adams, Julian
Published in Journal of medicinal chemistry (13.11.2008)
Published in Journal of medicinal chemistry (13.11.2008)
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Journal Article
Factors Associated With Specialists' Intention to Adopt New Behaviors After Taking Web-Based Continuing Professional Development Courses: Cross-sectional Study
Bergeron, Lysa, Décary, Simon, Djade, Codjo Djignefa, Daniel, Sam J, Tremblay, Martin, Rivest, Louis-Paul, Légaré, France
Published in JMIR medical education (02.06.2022)
Published in JMIR medical education (02.06.2022)
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Journal Article
Implementation of Interdisciplinary Province-Wide Webinar Series During the COVID-19 Pandemic by the Federation of Medical Specialists of Quebec (FMSQ): A Survey Study
Turkdogan, Sena, Chen, Tanya, McHugh, Tobial, Tremblay, Martin, Francoeur, Diane, Daniel, Sam J.
Published in Frontiers in medicine (09.09.2021)
Published in Frontiers in medicine (09.09.2021)
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Journal Article
Use of the CPD-REACTION Questionnaire to Evaluate Continuing Professional Development Activities for Health Professionals: Systematic Review
Ayivi-Vinz, Gloria, Bakwa Kanyinga, Felly, Bergeron, Lysa, Décary, Simon, Adisso, Évèhouénou Lionel, Zomahoun, Hervé Tchala Vignon, Daniel, Sam J, Tremblay, Martin, Plourde, Karine V, Guay-Bélanger, Sabrina, Légaré, France
Published in JMIR medical education (02.05.2022)
Published in JMIR medical education (02.05.2022)
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Inhibition of HIV-1 capsid assembly: Optimization of the antiviral potency by site selective modifications at N1, C2 and C16 of a 5-(5-furan-2-yl-pyrazol-1-yl)-1H-benzimidazole scaffold
Tremblay, Martin, Bonneau, Pierre, Bousquet, Yves, DeRoy, Patrick, Duan, Jianmin, Duplessis, Martin, Gagnon, Alexandre, Garneau, Michel, Goudreau, Nathalie, Guse, Ingrid, Hucke, Oliver, Kawai, Stephen H., Lemke, Christopher T., Mason, Stephen W., Simoneau, Bruno, Surprenant, Simon, Titolo, Steve, Yoakim, Christiane
Published in Bioorganic & medicinal chemistry letters (15.12.2012)
Published in Bioorganic & medicinal chemistry letters (15.12.2012)
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Journal Article
Development of a Multi Kilogram-Scale, Tandem Cyclopropanation Ring-Expansion Reaction en Route to Hedgehog Antagonist IPI-926
Austad, Brian C, Hague, Andrew B, White, Priscilla, Peluso, Stéphane, Nair, Somarajan J, Depew, Kristopher M, Grogan, Michael J, Charette, André B, Yu, Lin-Chen, Lory, Caroline D, Grenier, Louis, Lescarbeau, André, Lane, Benjamin S, Lombardy, Richard, Behnke, Mark L, Koney, Nii, Porter, James R, Campbell, Matthew J, Shaffer, Jeanne, Xiong, Jimin, Helble, Joseph C, Foley, Michael A, Adams, Julian, Castro, Alfredo C, Tremblay, Martin R
Published in Organic process research & development (15.04.2016)
Published in Organic process research & development (15.04.2016)
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Journal Article
In Vitro and In Vivo Anticancer Activities of Synthetic (-)-Laulimalide, a Marine Natural Product Microtubule Stabilizing Agent
JUNKE LIU, TOWLE, Murray J, HONGJUAN ZHAO, PESANT, Marc, FANG, Francis G, VERMEULEN, Mary W, GALLAGHER, Brian M, LITTLEFIELD, Bruce A, HONGSHENG CHENG, SAXTON, Philip, REARDON, Cathy, JIAYI WU, MURPHY, Erin A, KUZNETSOV, Galina, JOHANNES, Charles W, TREMBLAY, Martin R
Published in Anticancer research (01.05.2007)
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Published in Anticancer research (01.05.2007)
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