Colorectal cancer-specific cytochrome P450 2W1: intracellular localization, glycosylation, and catalytic activity
Gomez, Alvin, Nekvindova, Jana, Travica, Sandra, Lee, Mi-Young, Johansson, Inger, Edler, David, Mkrtchian, Souren, Ingelman-Sundberg, Magnus
Published in Molecular pharmacology (01.12.2010)
Published in Molecular pharmacology (01.12.2010)
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Colon Cancer―Specific Cytochrome P450 2W1 Converts Duocarmycin Analogues into Potent Tumor Cytotoxins
TRAVICA, Sandra, PORS, Klaus, LOADMAN, Paul M, SHNYDER, Steven D, JOHANSSON, Inger, ALANDAS, Mohammed N, SHELDRAKE, Helen M, MKRTCHIAN, Souren, PATTERSON, Laurence H, INGELMAN-SUNDBERG, Magnus
Published in Clinical cancer research (01.06.2013)
Published in Clinical cancer research (01.06.2013)
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Re-engineering of the Duocarmycin Structural Architecture Enables Bioprecursor Development Targeting CYP1A1 and CYP2W1 for Biological Activity
Sheldrake, Helen M, Travica, Sandra, Johansson, Inger, Loadman, Paul M, Sutherland, Mark, Elsalem, Lina, Illingworth, Nicola, Cresswell, Alexander J, Reuillon, Tristan, Shnyder, Steven D, Mkrtchian, Souren, Searcey, Mark, Ingelman-Sundberg, Magnus, Patterson, Laurence H, Pors, Klaus
Published in Journal of medicinal chemistry (08.08.2013)
Published in Journal of medicinal chemistry (08.08.2013)
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Abstract 1779: CYP2W1 as a novel therapeutic target in colon cancer
Pors, Klaus, Loadman, Paul M., Travica, Sandra, Shnyder, Steven D., Sutherland, Mark, Sheldrake, Helen, Searcey, Mark, Johansson, Inger, Mkrtchian, Souren, Ingelman-Sundberg, Magnus, Patterson, Laurence H.
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Abstract 2224: Re-engineering of the duocarmycin structural architecture enables tumour-selective CYP2W1-mediated drug activation in human colon cancer xenografts
Pors, Klaus, Travica, Sandra, Loadman, Paul M., Shnyder, Steven D., Sutherland, Mark, Sheldrake, Helen M., Searcey, Mark, Johansson, Inger, Mkrtchian, Souren, IngelmanSundberg, Magnus, Patterson, Laurence H.
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
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CYP2W1 polymorphism: functional aspects and relation to risk for colorectal cancer
Stenstedt, Kristina, Travica, Sandra, Guo, Jia, Barragan, Isabel, Pors, Klaus, Patterson, Laurence, Edler, David, Mkrtchian, Souren, Johansson, Inger, Ingelman-Sundberg, Magnus
Published in Pharmacogenomics (01.10.2013)
Published in Pharmacogenomics (01.10.2013)
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CXADR-Mediated Formation of an AKT Inhibitory Signalosome at Tight Junctions Controls Epithelial-Mesenchymal Plasticity in Breast Cancer
Nilchian, Azadeh, Johansson, Joel, Ghalali, Aram, Asanin, Sandra T, Santiago, Ana, Rosencrantz, Oskar, Sollerbrant, Kerstin, Vincent, C Theresa, Sund, Malin, Stenius, Ulla, Fuxe, Jonas
Published in Cancer research (Chicago, Ill.) (01.01.2019)
Published in Cancer research (Chicago, Ill.) (01.01.2019)
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