Search Results - "TRAN-DUBE, MICHELLE" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Cu-Catalyzed Hydroboration of Benzylidenecyclopropanes: Reaction Optimization, (Hetero)Aryl Scope, and Origins of Pathway Selectivity

Cu-Catalyzed Hydroboration of Benzylidenecyclopropanes: Reaction Optimization, (Hetero)Aryl Scope, and Origins of Pathway Selectivity

by Medina, Jose M, Kang, Taeho, Erbay, Tuğçe G, Shao, Huiling, Gallego, Gary M, Yang, Shouliang, Tran-Dubé, Michelle, Richardson, Paul F, Derosa, Joseph, Helsel, Ryan T, Patman, Ryan L, Wang, Fen, Ashcroft, Christopher P, Braganza, John F, McAlpine, Indrawan, Liu, Peng, Engle, Keary M
Published in ACS catalysis (06.12.2019)

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Discovery of Potent, Selective, and Peripherally Restricted Pan-Trk Kinase Inhibitors for the Treatment of Pain

Discovery of Potent, Selective, and Peripherally Restricted Pan-Trk Kinase Inhibitors for the Treatment of Pain

by Bagal, Sharan K, Andrews, Mark, Bechle, Bruce M, Bian, Jianwei, Bilsland, James, Blakemore, David C, Braganza, John F, Bungay, Peter J, Corbett, Matthew S, Cronin, Ciaran N, Cui, Jingrong Jean, Dias, Rebecca, Flanagan, Neil J, Greasley, Samantha E, Grimley, Rachel, James, Kim, Johnson, Eric, Kitching, Linda, Kraus, Michelle L, McAlpine, Indrawan, Nagata, Asako, Ninkovic, Sacha, Omoto, Kiyoyuki, Scales, Stephanie, Skerratt, Sarah E, Sun, Jianmin, Tran-Dubé, Michelle, Waldron, Gareth J, Wang, Fen, Warmus, Joseph S
Published in Journal of medicinal chemistry (09.08.2018)

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Journal Article

Structure Based Drug Design of Crizotinib (PF-02341066), a Potent and Selective Dual Inhibitor of Mesenchymal–Epithelial Transition Factor (c-MET) Kinase and Anaplastic Lymphoma Kinase (ALK)

Structure Based Drug Design of Crizotinib (PF-02341066), a Potent and Selective Dual Inhibitor of Mesenchymal–Epithelial Transition Factor (c-MET) Kinase and Anaplastic Lymphoma Kinase (ALK)

by Cui, J. Jean, Tran-Dubé, Michelle, Shen, Hong, Nambu, Mitchell, Kung, Pei-Pei, Pairish, Mason, Jia, Lei, Meng, Jerry, Funk, Lee, Botrous, Iriny, McTigue, Michele, Grodsky, Neil, Ryan, Kevin, Padrique, Ellen, Alton, Gordon, Timofeevski, Sergei, Yamazaki, Shinji, Li, Qiuhua, Zou, Helen, Christensen, James, Mroczkowski, Barbara, Bender, Steve, Kania, Robert S, Edwards, Martin P
Published in Journal of medicinal chemistry (22.09.2011)

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Rhodium(III)-Catalyzed C–H Activation: Ligand-Controlled Regioselective Synthesis of 4‑Methyl-Substituted Dihydroisoquinolones

Rhodium(III)-Catalyzed C–H Activation: Ligand-Controlled Regioselective Synthesis of 4‑Methyl-Substituted Dihydroisoquinolones

by Barber, Joyann S, Scales, Stephanie, Tran-Dubé, Michelle, Wang, Fen, Sach, Neal W, Bernier, Louise, Collins, Michael R, Zhu, JinJiang, McAlpine, Indrawan J, Patman, Ryan L
Published in Organic letters (19.07.2019)

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A Disconnection for Rapid Access to Heterocyclic Benzylic Amines with Fully Substituted α‑Carbons

A Disconnection for Rapid Access to Heterocyclic Benzylic Amines with Fully Substituted α‑Carbons

by Yang, Shouliang, Wang, Fen, Scales, Stephanie, Tran-Dubé, Michelle, Berry, Madeline, Xu, Haiwei, Tang, Feng, Xue, Liangliang, Ma, Zhongwei, Li, Bryan, McAlpine, Indrawan
Published in Journal of organic chemistry (15.03.2024)

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Journal Article

Copper-Catalyzed Chan–Lam Cyclopropylation of Phenols and Azaheterocycles

Copper-Catalyzed Chan–Lam Cyclopropylation of Phenols and Azaheterocycles

by Derosa, Joseph, O’Duill, Miriam L, Holcomb, Matthew, Boulous, Mark N, Patman, Ryan L, Wang, Fen, Tran-Dubé, Michelle, McAlpine, Indrawan, Engle, Keary M
Published in Journal of organic chemistry (06.04.2018)

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Anti-selective [3+2] (Hetero)annulation of non-conjugated alkenes via directed nucleopalladation

Anti-selective [3+2] (Hetero)annulation of non-conjugated alkenes via directed nucleopalladation

by Ni, Hui-Qi, Kevlishvili, Ilia, Bedekar, Pranali G., Barber, Joyann S., Yang, Shouliang, Tran-Dubé, Michelle, Romine, Andrew M., Lu, Hou-Xiang, McAlpine, Indrawan J., Liu, Peng, Engle, Keary M.
Published in Nature communications (22.12.2020)

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Mapping Ambiphile Reactivity Trends in the Anti-(Hetero)annulation of Non-Conjugated Alkenes via Pd-II/Pd-IV Catalysis

Mapping Ambiphile Reactivity Trends in the Anti-(Hetero)annulation of Non-Conjugated Alkenes via Pd-II/Pd-IV Catalysis

by Ni, Hui-Qi, Cooper, Phillippa, Yang, Shouliang, Wang, Fen, Sach, Neal, Bedekar, Pranali G., Donaldson, Joyann S., Tran-Dube, Michelle, McAlpine, Indrawan J., Engle, Keary M.
Published in Angewandte Chemie International Edition (21.03.2022)

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Journal Article

Construction of Isoquinolone Scaffolds on DNA via Rhodium(III)-Catalyzed C–H Activation

Construction of Isoquinolone Scaffolds on DNA via Rhodium(III)-Catalyzed C–H Activation

by Ye, Yusong, Berry, Madeline, Bock, William J., Cheng, Kunpeng, Nair, Sajiv K., Park, Christiana S., Patman, Ryan L., Sakata, Sylvie, Tran-Dubé, Michelle, Donaldson, Joyann S., Yang, Guanyu, Liu, Guansai
Published in Organic letters (26.04.2024)

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Discovery of a Novel Class of Exquisitely Selective Mesenchymal-Epithelial Transition Factor (c-MET) Protein Kinase Inhibitors and Identification of the Clinical Candidate 2‑(4-(1-(Quinolin-6-ylmethyl)‑1H‑[1,2,3]triazolo[4,5‑b]pyrazin-6-yl)‑1H‑pyrazol-1-yl)ethanol (PF-04217903) for the Treatment of Cancer

Discovery of a Novel Class of Exquisitely Selective Mesenchymal-Epithelial Transition Factor (c-MET) Protein Kinase Inhibitors and Identification of the Clinical Candidate 2‑(4-(1-(Quinolin-6-ylmethyl)‑1H‑[1,2,3]triazolo[4,5‑b]pyrazin-6-yl)‑1H‑pyrazol-1-yl)ethanol (PF-04217903) for the Treatment of Cancer

by Cui, J. Jean, McTigue, Michele, Nambu, Mitchell, Tran-Dubé, Michelle, Pairish, Mason, Shen, Hong, Jia, Lei, Cheng, Hengmiao, Hoffman, Jacqui, Le, Phuong, Jalaie, Mehran, Goetz, Gilles H, Ryan, Kevin, Grodsky, Neil, Deng, Ya-li, Parker, Max, Timofeevski, Sergei, Murray, Brion W, Yamazaki, Shinji, Aguirre, Shirley, Li, Qiuhua, Zou, Helen, Christensen, James
Published in Journal of medicinal chemistry (27.09.2012)

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Journal Article

Synthesis of Small 3‑Fluoro- and 3,3-Difluoropyrrolidines Using Azomethine Ylide Chemistry

Synthesis of Small 3‑Fluoro- and 3,3-Difluoropyrrolidines Using Azomethine Ylide Chemistry

by McAlpine, Indrawan, Tran-Dubé, Michelle, Wang, Fen, Scales, Stephanie, Matthews, Jean, Collins, Michael R, Nair, Sajiv K, Nguyen, Mary, Bian, Jianwei, Alsina, Luis Martinez, Sun, Jianmin, Zhong, Jiaying, Warmus, Joseph S, O’Neill, Brian T
Published in Journal of organic chemistry (17.07.2015)

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Journal Article

Mapping Ambiphile Reactivity Trends in the Anti‐(Hetero)annulation of Non‐Conjugated Alkenes via PdII/PdIV Catalysis

Mapping Ambiphile Reactivity Trends in the Anti‐(Hetero)annulation of Non‐Conjugated Alkenes via PdII/PdIV Catalysis

by Ni, Hui‐Qi, Cooper, Phillippa, Yang, Shouliang, Wang, Fen, Sach, Neal, Bedekar, Pranali G., Donaldson, Joyann S., Tran‐Dubé, Michelle, McAlpine, Indrawan J., Engle, Keary M.
Published in Angewandte Chemie International Edition (21.03.2022)

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Journal Article

Development of a Late-Stage Diversification Strategy for the 4- and 5‑Positions of 4,5,6-Trisubstituted Indazoles

Development of a Late-Stage Diversification Strategy for the 4- and 5‑Positions of 4,5,6-Trisubstituted Indazoles

by Barber, Joyann S, Burtea, Alexander, Collins, Michael R, Tran-Dubé, Michelle, Patman, Ryan L, Scales, Stephanie, Smith, Graham, Spangler, Jillian E, Wang, Fen, Wang, Wei, Yang, Shouliang, Zhu, JinJiang, Montgomery, T. Patrick
Published in Organic letters (20.11.2020)

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Journal Article

Lessons from (S)‑6-(1-(6-(1-Methyl‑1H‑pyrazol-4-yl)-[1,2,4]triazolo[4,3‑b]pyridazin-3-yl)ethyl)quinoline (PF-04254644), an Inhibitor of Receptor Tyrosine Kinase c‑Met with High Protein Kinase Selectivity but Broad Phosphodiesterase Family Inhibition Leading to Myocardial Degeneration in Rats

Lessons from (S)‑6-(1-(6-(1-Methyl‑1H‑pyrazol-4-yl)-[1,2,4]triazolo[4,3‑b]pyridazin-3-yl)ethyl)quinoline (PF-04254644), an Inhibitor of Receptor Tyrosine Kinase c‑Met with High Protein Kinase Selectivity but Broad Phosphodiesterase Family Inhibition Leading to Myocardial Degeneration in Rats

by Cui, J. Jean, Shen, Hong, Tran-Dubé, Michelle, Nambu, Mitchell, McTigue, Michele, Grodsky, Neil, Ryan, Kevin, Yamazaki, Shinji, Aguirre, Shirley, Parker, Max, Li, Qiuhua, Zou, Helen, Christensen, James
Published in Journal of medicinal chemistry (12.09.2013)

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Journal Article

Synthesis of Aryl Ethers via a Sulfonyl Transfer Reaction

Synthesis of Aryl Ethers via a Sulfonyl Transfer Reaction

by Sach, Neal W, Richter, Daniel T, Cripps, Stephan, Tran-Dubé, Michelle, Zhu, Huichun, Huang, Buwen, Cui, Jean, Sutton, Scott C
Published in Organic letters (03.08.2012)

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Journal Article

A two-step, one-pot procedure using acid chlorides and propargyl amines to form tri-substituted oxazoles via gold-catalyzed cyclization

A two-step, one-pot procedure using acid chlorides and propargyl amines to form tri-substituted oxazoles via gold-catalyzed cyclization

by Tran-Dubé, Michelle, Johnson, Sarah, McAlpine, Indrawan
Published in Tetrahedron letters (16.01.2013)

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Journal Article

SUBSTITUTED CARBONUCLEOSIDE DERIVATIVES USEFUL AS ANTICANCER AGENTS

SUBSTITUTED CARBONUCLEOSIDE DERIVATIVES USEFUL AS ANTICANCER AGENTS

by WYTHES MARTIN JAMES, TATLOCK JOHN HOWARD, MCTIGUE MICHELE ANN, MCALPINE INDRAWAN JAMES, TRAN DUBE MICHELLE BICH, KUMPF ROBERT ARNOLD, PATMAN RYAN, RUI EUGENE YUANJIN
Year of Publication 17.02.2021

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Patent

A simple and convenient two-step, one-pot synthesis of hetero-imidazoles from nitroaminoaryls catalyzed by Ytterbium triflate

A simple and convenient two-step, one-pot synthesis of hetero-imidazoles from nitroaminoaryls catalyzed by Ytterbium triflate

by Wang, Fen, Tran-Dubé, Michelle, Scales, Stephanie, Johnson, Sarah, McAlpine, Indrawan, Ninkovic, Sacha
Published in Tetrahedron letters (31.07.2013)

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Journal Article

항암제로서 유용한 치환된 카르보뉴클레오시드 유도체

항암제로서 유용한 치환된 카르보뉴클레오시드 유도체

by WYTHES MARTIN JAMES, TATLOCK JOHN HOWARD, MCTIGUE MICHELE ANN, MCALPINE INDRAWAN JAMES, TRAN DUBE MICHELLE BICH, KUMPF ROBERT ARNOLD, PATMAN RYAN, RUI EUGENE YUANJIN
Year of Publication 14.02.2019

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Patent

Improved cyclization conditions to prepare 6-substituted pyrazolo[1,5-a]pyridines and pyrazolo[1,5-a]pyrazines using catalytic Ag(I) and Au(III) salts

Improved cyclization conditions to prepare 6-substituted pyrazolo[1,5-a]pyridines and pyrazolo[1,5-a]pyrazines using catalytic Ag(I) and Au(III) salts

by Braganza, John F., Bernier, Louise, Botrous, Iriny, Collins, Michael R., Li, Baohua, McAlpine, Indrawan, Ninkovic, Sacha, Ren, Shijian, Sach, Neal, Tran-Dubé, Michelle, Zeng, Qingbin, Zheng, Baojiang
Published in Tetrahedron letters (14.10.2015)

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