Structure−Activity Relationship for Thiohydantoin Androgen Receptor Antagonists for Castration-Resistant Prostate Cancer (CRPC)
Jung, Michael E, Ouk, Samedy, Yoo, Dongwon, Sawyers, Charles L, Chen, Charlie, Tran, Chris, Wongvipat, John
Published in Journal of medicinal chemistry (08.04.2010)
Published in Journal of medicinal chemistry (08.04.2010)
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Development of a Second-Generation Antiandrogen for Treatment of Advanced Prostate Cancer
Tran, Chris, Ouk, Samedy, Clegg, Nicola J, Chen, Yu, Watson, Philip A, Arora, Vivek, Wongvipat, John, Smith-Jones, Peter M, Yoo, Dongwon, Kwon, Andrew, Wasielewska, Teresa, Welsbie, Derek, Chen, Charlie Degui, Higano, Celestia S, Beer, Tomasz M, Hung, David T, Scher, Howard I, Jung, Michael E, Sawyers, Charles L
Published in Science (American Association for the Advancement of Science) (08.05.2009)
Published in Science (American Association for the Advancement of Science) (08.05.2009)
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ARN-509: A Novel Antiandrogen for Prostate Cancer Treatment
CLEGG, Nicola J, WONGVIPAT, John, APARICIO, Anna, DOROW, Steven, ARORA, Vivek, GANG SHAO, JING QIAN, HONG ZHAO, GUANGBIN YANG, CHUNYAN CAO, SENSINTAFFAR, John, WASIELEWSKA, Teresa, JOSEPH, James D, HERBERT, Mark R, BONNEFOUS, Celine, DARIMONT, Beatrice, SCHER, Howard I, SMITH-JONES, Peter, KLANG, Mark, SMITH, Nicholas D, DE STANCHINA, Elisa, NIAN WU, OUERFELLI, Ouathek, TRAN, Chris, RIX, Peter J, HEYMAN, Richard A, JUNG, Michael E, SAWYERS, Charles L, HAGER, Jeffrey H, OUK, Samedy, DILHAS, Anna, YU CHEN, GRILLOT, Kate, BISCHOFF, Eric D, LING CAI
Published in Cancer research (Chicago, Ill.) (15.03.2012)
Published in Cancer research (Chicago, Ill.) (15.03.2012)
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Nonclinical Pharmacokinetics and Absorption, Distribution, Metabolism, and Excretion of Givosiran, the First Approved N -Acetylgalactosamine-Conjugated RNA Interference Therapeutic
Li, Jing, Liu, Ju, Zhang, Xuemei, Clausen, Valerie, Tran, Chris, Arciprete, Michael, Wang, Qianfan, Rocca, Carrie, Guan, Li-Hua, Zhang, Guodong, Najarian, Diana, Xu, Yuanxin, Smith, Peter, Wu, Jing-Tao, Chong, Saeho
Published in Drug metabolism and disposition (01.07.2021)
Published in Drug metabolism and disposition (01.07.2021)
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Synthesis and application of β-carbolines as novel multi-functional anti-Alzheimer’s disease agents
Horton, William, Sood, Abha, Peerannawar, Swarada, Kugyela, Nandor, Kulkarni, Aditya, Tulsan, Rekha, Tran, Chris D., Soule, Jessica, LeVine, Harry, Török, Béla, Török, Marianna
Published in Bioorganic & medicinal chemistry letters (15.01.2017)
Published in Bioorganic & medicinal chemistry letters (15.01.2017)
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Identification of the JNK Signaling Pathway as a Functional Target of the Tumor Suppressor PTEN
Vivanco, Igor, Palaskas, Nicolaos, Tran, Chris, Finn, Stephen P., Getz, Gad, Kennedy, Norman J., Jiao, Jing, Rose, Joshua, Xie, Wanling, Loda, Massimo, Golub, Todd, Mellinghoff, Ingo K., Davis, Roger J., Wu, Hong, Sawyers, Charles L.
Published in Cancer cell (01.06.2007)
Published in Cancer cell (01.06.2007)
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Enhanced Sensitivity of PTEN-Deficient Tumors to Inhibition of FRAP/mTOR
Neshat, Mehran S., Mellinghoff, Ingo K., Tran, Chris, Stiles, Bangyan, Thomas, George, Petersen, Roseann, Frost, Philip, Gibbons, James J., Wu, Hong, Sawyers, Charles L.
Published in Proceedings of the National Academy of Sciences - PNAS (28.08.2001)
Published in Proceedings of the National Academy of Sciences - PNAS (28.08.2001)
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AKT Activity Determines Sensitivity to Mammalian Target of Rapamycin (mTOR) Inhibitors by Regulating Cyclin D1 and c-myc Expression
Gera, Joseph F., Mellinghoff, Ingo K., Shi, Yijiang, Rettig, Matthew B., Tran, Chris, Hsu, Jung-hsin, Sawyers, Charles L., Lichtenstein, Alan K.
Published in The Journal of biological chemistry (23.01.2004)
Published in The Journal of biological chemistry (23.01.2004)
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Environmentally benign, microwave-assisted chemoselective N-hydroxyalkylation of indoles with trifluoroacetaldehyde methyl hemiacetal
Schäfer, Christian, Ellstrom, Clifford J., Sood, Abha, Alonzo, Judith, Tran, Shainaz M. Landge Chris D., Török, Béla
Published in ARKIVOC free online journal of organic chemistry (01.01.2018)
Published in ARKIVOC free online journal of organic chemistry (01.01.2018)
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Inactivation of the Tumor Suppressor PTEN/MMAC1 in Advanced Human Prostate Cancer through Loss of Expression
Whang, Young E., Wu, Xinyi, Suzuki, Hiroyoshi, Reiter, Robert E., Tran, Chris, Vessella, Robert L., Said, Jonathan W., Isaacs, William B., Sawyers, Charles L.
Published in Proceedings of the National Academy of Sciences - PNAS (28.04.1998)
Published in Proceedings of the National Academy of Sciences - PNAS (28.04.1998)
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ALT100, A Designed Peptide Targeting α-sheet Amyloid-β Oligomers, Improves Behavior in an ICV Oligomeric Aβ Mouse Model
Tallon, Carolyn, Gajera, Chandresh, Tran, Chris, Posakony, Jeff, Watt, Charles, Block, Gill, Daggett, Valerie
Published in Neurotherapeutics (01.07.2024)
Published in Neurotherapeutics (01.07.2024)
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Effect of Isocaloric Low-fat Diet on Human LAPC-4 Prostate Cancer Xenografts in Severe Combined Immunodeficient Mice and the Insulin-like Growth Factor Axis
NGO, Tung H, BARNARD, R. James, COHEN, Pinchas, FREEDLAND, Stephen, TRAN, Chris, DEGREGORIO, Frank, ELSHIMALI, Yahya I, HEBER, David, ARONSON, William J
Published in Clinical cancer research (01.07.2003)
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Published in Clinical cancer research (01.07.2003)
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18F-Fluorodeoxy-glucose Positron Emission Tomography Marks MYC-Overexpressing Human Basal-Like Breast Cancers
PALASKAS, Nicolaos, LARSON, Steven M, KASTENHUBER, Edward R, TASCHEREAU, Richard, PLAISIER, Seema B, TRAN, Chris, HEGUY, Adriana, HONG WU, SANDER, Chris, PHELPS, Michael E, BRENNAN, Cameron, PORT, Elisa, SCHULTZ, Nikolaus, HUSE, Jason T, GRAEBER, Thomas G, MELLINGHOFF, Ingo K, KOMISOPOULOU, Evangelia, WONG, Justin, ROHLE, Dan, CAMPOS, Carl, YANNUZZI, Nicolas, OSBORNE, Joseph R, LINKOV, Irina
Published in Cancer research (Chicago, Ill.) (01.08.2011)
Published in Cancer research (Chicago, Ill.) (01.08.2011)
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Effect of isocaloric low-fat diet on prostate cancer xenograft progression to androgen independence
NGO, Tung H, BARNARD, R. James, ANTON, Todd, TRAN, Chris, ELASHOFF, David, HEBER, David, FREEDLAND, Stephen J, ARONSON, William J
Published in Cancer research (Chicago, Ill.) (15.02.2004)
Published in Cancer research (Chicago, Ill.) (15.02.2004)
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c-Abl Is Required for Development and Optimal Cell Proliferation in the Context of p53 Deficiency
Whang, Young E., Tran, Chris, Henderson, Cailin, Syljuasen, Randi G., Rozengurt, Nora, McBride, William H., Sawyers, Charles L.
Published in Proceedings of the National Academy of Sciences - PNAS (09.05.2000)
Published in Proceedings of the National Academy of Sciences - PNAS (09.05.2000)
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Safety evaluation of 2′-deoxy-2′-fluoro nucleotides in GalNAc-siRNA conjugates
Janas, Maja M, Zlatev, Ivan, Liu, Ju, Jiang, Yongfeng, Barros, Scott A, Sutherland, Jessica E, Davis, Wendell P, Liu, Jingxuan, Brown, Christopher R, Liu, Xiumin, Schlegel, Mark K, Blair, Lauren, Zhang, Xuemei, Das, Biplab, Tran, Chris, Aluri, Krishna, Li, Jing, Agarwal, Saket, Indrakanti, Ramesh, Charisse, Klaus, Nair, Jayaprakash, Matsuda, Shigeo, Rajeev, Kallanthottathil G, Zimmermann, Tracy, Sepp-Lorenzino, Laura, Xu, Yuanxin, Akinc, Akin, Fitzgerald, Kevin, Vaishnaw, Akshay K, Smith, Peter F, Manoharan, Muthiah, Jadhav, Vasant, Wu, Jing-Tao, Maier, Martin A
Published in Nucleic acids research (23.04.2019)
Published in Nucleic acids research (23.04.2019)
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