Topiramate and Phenytoin Pharmacokinetics During Repetitive Monotherapy and Combination Therapy to Epileptic Patients
Sachdeo, R. C., Sachdeo, S. K., Levy, R. H., Streeter, A. J., Bishop, F. E., Kunze, K. L., Mather, G. G., Roskos, L. K., Shen, D. D., Thummel, K. E., Trager, W. F., Curtin, C. R., Doose, Dennis R., Gisclon, L. G., Bialer, Meir
Published in Epilepsia (Copenhagen) (01.07.2002)
Published in Epilepsia (Copenhagen) (01.07.2002)
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Use of midazolam as a human cytochrome P450 3A probe: I. In vitro-in vivo correlations in liver transplant patients
Thummel, K E, Shen, D D, Podoll, T D, Kunze, K L, Trager, W F, Hartwell, P S, Raisys, V A, Marsh, C L, McVicar, J P, Barr, D M
Published in The Journal of pharmacology and experimental therapeutics (01.10.1994)
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Published in The Journal of pharmacology and experimental therapeutics (01.10.1994)
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Mechanism-Based Inactivation of Human Liver Cytochrome P450 2A6 by 8-Methoxypsoralen
KOENIGS, L. L, PETER, R. M, THOMPSON, S. J, RETTIE, A. E, TRAGER, W. F
Published in Drug metabolism and disposition (01.12.1997)
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Published in Drug metabolism and disposition (01.12.1997)
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Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin-drug interactions
Rettie, Allan E, Korzekwa, Kenneth R, Kunze, Kent L, Lawrence, Ross F, Eddy, A Craig, Aoyama, Toshifumi, Gelboin, Harry V, Gonzalez, Frank J, Trager, William F
Published in Chemical research in toxicology (01.01.1992)
Published in Chemical research in toxicology (01.01.1992)
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Warfarin-fluconazole. II. A metabolically based drug interaction: in vivo studies
Black, D J, Kunze, K L, Wienkers, L C, Gidal, B E, Seaton, T L, McDonnell, N D, Evans, J S, Bauwens, J E, Trager, W F
Published in Drug metabolism and disposition (01.04.1996)
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Published in Drug metabolism and disposition (01.04.1996)
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Use of midazolam as a human cytochrome P450 3A probe: II. Characterization of inter- and intraindividual hepatic CYP3A variability after liver transplantation
Thummel, K E, Shen, D D, Podoll, T D, Kunze, K L, Trager, W F, Bacchi, C E, Marsh, C L, McVicar, J P, Barr, D M, Perkins, J D
Published in The Journal of pharmacology and experimental therapeutics (01.10.1994)
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Published in The Journal of pharmacology and experimental therapeutics (01.10.1994)
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Formation of (R)-8-hydroxywarfarin in human liver microsomes. A new metabolic marker for the (S)-mephenytoin hydroxylase, P4502C19
Wienkers, L C, Wurden, C J, Storch, E, Kunze, K L, Rettie, A E, Trager, W F
Published in Drug metabolism and disposition (01.05.1996)
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Published in Drug metabolism and disposition (01.05.1996)
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Three-dimensional quantitative structure-activity relationship for inhibitors of cytochrome P4502C9
Jones, J P, He, M, Trager, W F, Rettie, A E
Published in Drug metabolism and disposition (01.01.1996)
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Published in Drug metabolism and disposition (01.01.1996)
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Influence of stiripentol on cytochrome P450-mediated metabolic pathways in humans: in vitro and in vivo comparison and calculation of in vivo inhibition constants
Tran, A, Rey, E, Pons, G, Rousseau, M, d'Athis, P, Olive, G, Mather, G G, Bishop, F E, Wurden, C J, Labroo, R, Trager, W F, Kunze, K L, Thummel, K E, Vincent, J C, Gillardin, J M, Lepage, F, Levy, R H
Published in Clinical pharmacology and therapeutics (01.11.1997)
Published in Clinical pharmacology and therapeutics (01.11.1997)
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(R)-(+)-Menthofuran Is a Potent, Mechanism-Based Inactivator of Human Liver Cytochrome P450 2A6
KHOJASTEH-BAKHT, S. C, KOENIGS, L. L, PETER, R. M, TRAGER, W. F, NELSON, S. D
Published in Drug metabolism and disposition (01.07.1998)
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Published in Drug metabolism and disposition (01.07.1998)
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Catalytic role of cytochrome P4503A4 in multiple pathways of alfentanil metabolism
Labroo, R B, Thummel, K E, Kunze, K L, Podoll, T, Trager, W F, Kharasch, E D
Published in Drug metabolism and disposition (01.04.1995)
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Published in Drug metabolism and disposition (01.04.1995)
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Allelic Variants of Human Cytochrome P450 2C9: Baculovirus-Mediated Expression, Purification, Structural Characterization, Substrate Stereoselectivity, and Prochiral Selectivity of the Wild-Type and I359L Mutant Forms
Haining, Robert L., Hunter, Ann P., Veronese, Maurice E., Trager, William F., Rettie, Allan E.
Published in Archives of biochemistry and biophysics (15.09.1996)
Published in Archives of biochemistry and biophysics (15.09.1996)
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Oxidation of Acetaminophen to Its Toxic Quinone Imine and Nontoxic Catechol Metabolites by Baculovirus-Expressed and Purified Human Cytochromes P450 2E1 and 2A6
Chen, Weiqiao, Koenigs, Luke L, Thompson, Stella J, Peter, Raimund M, Rettie, Allan E, Trager, William F, Nelson, Sidney D
Published in Chemical research in toxicology (01.04.1998)
Published in Chemical research in toxicology (01.04.1998)
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