Programmable 3D silk bone marrow niche for platelet generation ex vivo and modeling of megakaryopoiesis pathologies
Di Buduo, Christian A., Wray, Lindsay S., Tozzi, Lorenzo, Malara, Alessandro, Chen, Ying, Ghezzi, Chiara E., Smoot, Daniel, Sfara, Carla, Antonelli, Antonella, Spedden, Elise, Bruni, Giovanna, Staii, Cristian, De Marco, Luigi, Magnani, Mauro, Kaplan, David L., Balduini, Alessandra
Published in Blood (02.04.2015)
Published in Blood (02.04.2015)
Get full text
Journal Article
The secret life of a megakaryocyte: emerging roles in bone marrow homeostasis control
Malara, Alessandro, Abbonante, Vittorio, Di Buduo, Christian A., Tozzi, Lorenzo, Currao, Manuela, Balduini, Alessandra
Published in Cellular and molecular life sciences : CMLS (01.04.2015)
Published in Cellular and molecular life sciences : CMLS (01.04.2015)
Get full text
Journal Article
mTOR inhibitors alone and in combination with JAK2 inhibitors effectively inhibit cells of myeloproliferative neoplasms
Bogani, Costanza, Bartalucci, Niccolò, Martinelli, Serena, Tozzi, Lorenzo, Guglielmelli, Paola, Bosi, Alberto, Vannucchi, Alessandro M
Published in PloS one (31.01.2013)
Published in PloS one (31.01.2013)
Get full text
Journal Article
Repetitive head injury in adolescent mice: A role for vascular inflammation
Wu, Limin, Chung, Joon Y, Saith, Shivani, Tozzi, Lorenzo, Buckley, Erin M, Sanders, Bharat, Franceschini, Maria A, Lule, Sevda, Izzy, Saef, Lok, Josephine, Edmiston, William J, McAllister, Lauren M, Mebane, Sloane, Jin, Gina, Lu, Jiaxi, Sherwood, John S, Willwerth, Sarah, Hickman, Suzanne, Khoury, Joseph El, Lo, Eng H, Kaplan, David, Whalen, Michael J
Published in Journal of cerebral blood flow and metabolism (01.11.2019)
Published in Journal of cerebral blood flow and metabolism (01.11.2019)
Get full text
Journal Article
Genetic inhibition of RIPK3 ameliorates functional outcome in controlled cortical impact independent of necroptosis
Wu, Limin, Chung, Joon Yong, Cao, Tian, Jin, Gina, Edmiston, William J., Hickman, Suzanne, Levy, Emily S., Whalen, Jordyn A., Abrams, Eliza Sophie LaRovere, Degterev, Alexei, Lo, Eng H., Tozzi, Lorenzo, Kaplan, David L., El Khoury, Joseph, Whalen, Michael J.
Published in Cell death & disease (09.11.2021)
Published in Cell death & disease (09.11.2021)
Get full text
Journal Article
Three‐Dimensional Humanized Model of the Periodontal Gingival Pocket to Study Oral Microbiome
Adelfio, Miryam, Martin‐Moldes, Zaira, Erndt‐Marino, Joshua, Tozzi, Lorenzo, Duncan, Margaret J., Hasturk, Hatice, Kaplan, David L., Ghezzi, Chiara E.
Published in Advanced science (01.04.2023)
Published in Advanced science (01.04.2023)
Get full text
Journal Article
Hydroxyurea does not appreciably reduce JAK2 V617F allele burden in patients with polycythemia vera or essential thrombocythemia
ANTONIOLI, Elisabetta, CAROBBIO, Alessandra, RAMBALDI, Alessandro, BARBUI, Tiziano, VANNUCCHI, Alessandro M, PIERI, Lisa, PANCRAZZI, Alessandro, GUGLIELMELLI, Paola, DELAINI, Federica, PONZIANI, Vanessa, BARTALUCCI, Niccolò, TOZZI, Lorenzo, BOSI, Alberto
Published in Haematologica (Roma) (01.08.2010)
Published in Haematologica (Roma) (01.08.2010)
Get full text
Journal Article
MicroRNA expression profile in granulocytes from primary myelofibrosis patients
Guglielmelli, Paola, Tozzi, Lorenzo, Pancrazzi, Alessandro, Bogani, Costanza, Antonioli, Elisabetta, Ponziani, Vanessa, Poli, Giada, Zini, Roberta, Ferrari, Sergio, Manfredini, Rossella, Bosi, Alberto, Vannucchi, Alessandro M
Published in Experimental hematology (01.11.2007)
Published in Experimental hematology (01.11.2007)
Get full text
Journal Article
High‐Strength, Durable All‐Silk Fibroin Hydrogels with Versatile Processability toward Multifunctional Applications
Zhu, Zhenghua, Ling, Shengjie, Yeo, Jingjie, Zhao, Siwei, Tozzi, Lorenzo, Buehler, Markus J., Omenetto, Fiorenzo, Li, Chunmei, Kaplan, David L.
Published in Advanced functional materials (07.03.2018)
Published in Advanced functional materials (07.03.2018)
Get full text
Journal Article
Influence of JAK2V617F allele burden on phenotype in essential thrombocythemia
Antonioli, Elisabetta, Guglielmelli, Paola, Poli, Giada, Bogani, Costanza, Pancrazzi, Alessandro, Longo, Giovanni, Ponziani, Vanessa, Tozzi, Lorenzo, Pieri, Lisa, Santini, Valeria, Bosi, Alberto, Vannucchi, Alessandro M, Myeloproliferative Disorders Research Consortium (MPD-RC)
Published in Haematologica (Roma) (01.01.2008)
Published in Haematologica (Roma) (01.01.2008)
Get full text
Journal Article
Multi-channel silk sponge mimicking bone marrow vascular niche for platelet production
Tozzi, Lorenzo, Laurent, Pierre-Alexandre, Di Buduo, Christian A, Mu, Xuan, Massaro, Angelo, Bretherton, Ross, Stoppel, Whitney, Kaplan, David L, Balduini, Alessandra
Published in Biomaterials (01.09.2018)
Published in Biomaterials (01.09.2018)
Get full text
Journal Article
Developing a self‐organized tubulogenesis model of human renal proximal tubular epithelial cells in vitro
Wang, Xiuli, Guo, Chengchen, Chen, Ying, Tozzi, Lorenzo, Szymkowiak, Sophia, Li, Chunmei, Kaplan, David L.
Published in Journal of biomedical materials research. Part A (01.03.2020)
Published in Journal of biomedical materials research. Part A (01.03.2020)
Get full text
Journal Article
In Vivo Delivery of RNA By Lipid Nanoparticles (LNP) to Hematopoietic Stem Cells and T Cells in Humanized Mice and Non-Human Primates
Monte, Michael T., Gu, Han, Saunders, Laura, Gupta, Mohit, Liu, Lei, Wangweerawong, Apiwat, Colace, Thomas V., Zannini, Aaron, Tozzi, Lorenzo, Cao, Yu, Schiroli, Giulia, Salomon, William E., Rottman, James B., Palchaudhuri, Rahul, Gerdemann, Ulrike, Gorfinkel, Lev, Alvarez Calderon, Francesca, Kean, Leslie, Pujar, Hari, Wang, Z. Jane
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
Get full text
Journal Article
Co‐targeting the PI3K/mTOR and JAK2 signalling pathways produces synergistic activity against myeloproliferative neoplasms
Bartalucci, Niccolò, Tozzi, Lorenzo, Bogani, Costanza, Martinelli, Serena, Rotunno, Giada, Villeval, Jean‐Luc, Vannucchi, Alessandro M.
Published in Journal of cellular and molecular medicine (01.11.2013)
Published in Journal of cellular and molecular medicine (01.11.2013)
Get full text
Journal Article
Safety and efficacy of everolimus, a mTOR inhibitor, as single agent in a phase 1/2 study in patients with myelofibrosis
Guglielmelli, Paola, Barosi, Giovanni, Rambaldi, Alessandro, Marchioli, Roberto, Masciulli, Arianna, Tozzi, Lorenzo, Biamonte, Flavia, Bartalucci, Niccolò, Gattoni, Elisabetta, Lupo, Maria Letizia, Finazzi, Guido, Pancrazzi, Alessandro, Antonioli, Elisabetta, Susini, Maria Chiara, Pieri, Lisa, Malevolti, Elisa, Usala, Emilio, Occhini, Ubaldo, Grossi, Alberto, Caglio, Silvia, Paratore, Simona, Bosi, Alberto, Barbui, Tiziano, Vannucchi, Alessandro M.
Published in Blood (25.08.2011)
Published in Blood (25.08.2011)
Get full text
Journal Article
Spleen endothelial cells from patients with myelofibrosis harbor the JAK2V617F mutation
Rosti, Vittorio, Villani, Laura, Riboni, Roberta, Poletto, Valentina, Bonetti, Elisa, Tozzi, Lorenzo, Bergamaschi, Gaetano, Catarsi, Paolo, Dallera, Elena, Novara, Francesca, Massa, Margherita, Campanelli, Rita, Fois, Gabriela, Peruzzi, Benedetta, Lucioni, Marco, Guglielmelli, Paola, Pancrazzi, Alessandro, Fiandrino, Giacomo, Zuffardi, Orsetta, Magrini, Umberto, Paulli, Marco, Vannucchi, Alessandro M., Barosi, Giovanni
Published in Blood (10.01.2013)
Published in Blood (10.01.2013)
Get full text
Journal Article
Biodegradable silk catheters for the delivery of therapeutics across anatomical repair sites
Brown, Joseph E, Tozzi, Lorenzo, Schilling, Benjamin, Kelmendi-Doko, Arta, Truong, April B, Rodriguez, Maria J, Gil, Eun Seok, Sucsy, Robert, Valentin, Jolene E, Philips, Brian J, Marra, Kacey G, Rubin, J Peter, Kaplan, David L
Published in Journal of biomedical materials research. Part B, Applied biomaterials (01.04.2019)
Published in Journal of biomedical materials research. Part B, Applied biomaterials (01.04.2019)
Get full text
Journal Article