Specificity and Structure of a High Affinity Activin Receptor-like Kinase 1 (ALK1) Signaling Complex
Townson, Sharon A., Martinez-Hackert, Erik, Greppi, Chloe, Lowden, Patricia, Sako, Dianne, Liu, June, Ucran, Jeffrey A., Liharska, Katia, Underwood, Kathryn W., Seehra, Jasbir, Kumar, Ravindra, Grinberg, Asya V.
Published in The Journal of biological chemistry (10.08.2012)
Published in The Journal of biological chemistry (10.08.2012)
Get full text
Journal Article
Crystal Structure of an HSA/FcRn Complex Reveals Recycling by Competitive Mimicry of HSA Ligands at a pH-Dependent Hydrophobic Interface
Schmidt, Michael M., Townson, Sharon A., Andreucci, Amy J., King, Bracken M., Schirmer, Emily B., Murillo, Alec J., Dombrowski, Christian, Tisdale, Alison W., Lowden, Patricia A., Masci, Allyson L., Kovalchin, Joseph T., Erbe, David V., Wittrup, K. Dane, Furfine, Eric S., Barnes, Thomas M.
Published in Structure (London) (05.11.2013)
Published in Structure (London) (05.11.2013)
Get full text
Journal Article
Design of a superior cytokine antagonist for topical ophthalmic use
Hou, Jinzhao, Townson, Sharon A., Kovalchin, Joseph T., Masci, Allyson, Kiner, Olga, Shu, Yanqun, King, Bracken M., Schirmer, Emily, Golden, Kathryn, Thomas, Christoph, Garcia, K. Christopher, Zarbis-Papastoitsis, Gregory, Furfine, Eric S., Barnes, Thomas M.
Published in Proceedings of the National Academy of Sciences - PNAS (05.03.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (05.03.2013)
Get full text
Journal Article
BstYI Bound to Noncognate DNA Reveals a “Hemispecific” Complex: Implications for DNA Scanning
Townson, Sharon A., Samuelson, James C., Bao, Yongming, Xu, Shuang-yong, Aggarwal, Aneel K.
Published in Structure (London) (01.04.2007)
Published in Structure (London) (01.04.2007)
Get full text
Journal Article
Genomic discovery of an evolutionarily programmed modality for small-molecule targeting of an intractable protein surface
Shigdel, Uddhav K., Lee, Seung-Joo, Sowa, Mathew E., Bowman, Brian R., Robison, Keith, Zhou, Minyun, Pua, Khian Hong, Stiles, Dylan T., Blodgett, Joshua A. V., Udwary, Daniel W., Rajczewski, Andrew T., Mann, Alan S., Mostafavi, Siavash, Hardy, Tara, Arya, Sukrat, Weng, Zhigang, Stewart, Michelle, Kenyon, Kyle, Morgenstern, Jay P., Pan, Ende, Gray, Daniel C., Pollock, Roy M., Fry, Andrew M., Klausner, Richard D., Townson, Sharon A., Verdine, Gregory L.
Published in Proceedings of the National Academy of Sciences - PNAS (21.07.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (21.07.2020)
Get full text
Journal Article
Human DNA Polymerase κ Encircles DNA: Implications for Mismatch Extension and Lesion Bypass
Lone, Samer, Townson, Sharon A., Uljon, Sacha N., Johnson, Robert E., Brahma, Amrita, Nair, Deepak T., Prakash, Satya, Prakash, Louise, Aggarwal, Aneel K.
Published in Molecular cell (23.02.2007)
Published in Molecular cell (23.02.2007)
Get full text
Journal Article
High-Throughput, Cell-Free, Liposome-Based Approach for Assessing In Vitro Activity of Lipid Kinases
Demian, Douglas J., Clugston, Susan L., Foster, Meta M., Rameh, Lucia, Sarkes, Deborah, Townson, Sharon A., Yang, Lily, Zhang, Melvin, Charlton, Maura E.
Published in Journal of biomolecular screening (01.08.2009)
Published in Journal of biomolecular screening (01.08.2009)
Get full text
Journal Article
NMR 1H,13C, 15N resonance assignment of the G12C mutant of human K-Ras bound to GppNHp
Sharma, Alok K., Lee, Seung-Joo, Zhou, Minyun, Rigby, Alan C., Townson, Sharon A.
Published in Biomolecular NMR assignments (01.04.2019)
Published in Biomolecular NMR assignments (01.04.2019)
Get full text
Journal Article
Crystallization and preliminary crystallographic analysis of the type IIL restriction enzyme MmeI in complex with DNA
Callahan, Scott J., Morgan, Richard D., Jain, Rinku, Townson, Sharon A., Wilson, Geoffrey G., Roberts, Richard J., Aggarwal, Aneel K.
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01.10.2011)
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01.10.2011)
Get full text
Journal Article
Crystal structure of BstYI at 1.85A resolution: a thermophilic restriction endonuclease with overlapping specificities to BamHI and BglII
Townson, Sharon A, Samuelson, James C, Vanamee, Eva Scheuring, Edwards, Thomas A, Escalante, Carlos R, Xu, Shuang-Yong, Aggarwal, Aneel K
Published in Journal of molecular biology (07.05.2004)
Published in Journal of molecular biology (07.05.2004)
Get full text
Journal Article
Abstract A06: Biophysical and biochemical characterization of KRAS G12C inhibition through the SMARTTM platform
Zhou, Minyun, Yuzhakov, Alexander, Benod, Cindy C, Xue, Linlong, Silver, Alec D, Iyer, Ganesh, Townson, Sharon A., Jin, Meizhong, Perl, Nicholas R., Kohlmann, Anna, Mann, Alan S., Akcay, Gizem, May, Earl W.
Published in Molecular cancer research (01.05.2020)
Published in Molecular cancer research (01.05.2020)
Get full text
Journal Article
Abstract B37: Development of inhibitors of the activated form of KRAS G12C
Stewart, Michelle L., Perl, Nicholas R., Lee, Seung-Joo, Xue, Linlong, Zhou, Minyun, Simon, Jonah, Luly, Kathryn M., Grigoriu, Siminia, Yuzhakov, Alex, Silver, Alec, Lowe, Jason T., Benod, Cindy C., Mann, Alan S., Verdine, Gregory L., Rigby, Alan C., Mulvihill, Mark J., May, Earl W., Kohlmann, Anna, Townson, Sharon A., Pollock, Roy M., Jin, Meizhong
Published in Molecular cancer research (01.05.2020)
Published in Molecular cancer research (01.05.2020)
Get full text
Journal Article
NMR 1 H, 13 C, 15 N resonance assignment of the G12C mutant of human K-Ras bound to GppNHp
Sharma, Alok K, Lee, Seung-Joo, Zhou, Minyun, Rigby, Alan C, Townson, Sharon A
Published in Biomolecular NMR assignments (01.04.2019)
Get full text
Published in Biomolecular NMR assignments (01.04.2019)
Journal Article
Crystal Structure of BstYI at 1.85 Å Resolution: A Thermophilic Restriction Endonuclease with Overlapping Specificities to BamHI and BglII
Townson, Sharon A., Samuelson, James C., Vanamee, Éva Scheuring, Edwards, Thomas A., Escalante, Carlos R., Xu, Shuang-yong, Aggarwal, Aneel K.
Published in Journal of molecular biology (07.05.2004)
Published in Journal of molecular biology (07.05.2004)
Get full text
Journal Article
Methods and reagents for analyzing protein-protein interfaces
Shigdel, Uddhav Kumar, Verdine, Gregory L, Anthony, Neville J, Lee, Seung-Joo, Nichols, M. James, Townson, Sharon A, Stiles, Dylan T
Year of Publication 08.02.2024
Get full text
Year of Publication 08.02.2024
Patent
METHODS AND REAGENTS FOR ANALYZING PROTEIN-PROTEIN INTERFACES
Shigdel, Uddhav Kumar, Verdine, Gregory L, Anthony, Neville J, Lee, Seung-Joo, Nichols, M. James, Townson, Sharon A, Stilles, Dylan T
Year of Publication 07.02.2024
Get full text
Year of Publication 07.02.2024
Patent