SARS‐CoV‐2 sensing by RIG‐I and MDA5 links epithelial infection to macrophage inflammation
Thorne, Lucy G, Reuschl, Ann‐Kathrin, Zuliani‐Alvarez, Lorena, Whelan, Matthew V X, Turner, Jane, Noursadeghi, Mahdad, Jolly, Clare, Towers, Greg J
Published in The EMBO journal (02.08.2021)
Published in The EMBO journal (02.08.2021)
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Journal Article
HIV-1 capsid-cyclophilin interactions determine nuclear import pathway, integration targeting and replication efficiency
Schaller, Torsten, Ocwieja, Karen E, Rasaiyaah, Jane, Price, Amanda J, Brady, Troy L, Roth, Shoshannah L, Hué, Stéphane, Fletcher, Adam J, Lee, KyeongEun, KewalRamani, Vineet N, Noursadeghi, Mahdad, Jenner, Richard G, James, Leo C, Bushman, Frederic D, Towers, Greg J
Published in PLoS pathogens (01.12.2011)
Published in PLoS pathogens (01.12.2011)
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Journal Article
Virulent Poxviruses Inhibit DNA Sensing by Preventing STING Activation
Georgana, Iliana, Sumner, Rebecca P, Towers, Greg J, Maluquer de Motes, Carlos
Published in Journal of virology (15.05.2018)
Published in Journal of virology (15.05.2018)
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Journal Article
Antibodies mediate intracellular immunity through tripartite motif-containing 21 (TRIM21)
Mallery, Donna L., McEwan, William A., Bidgood, Susanna R., Towers, Greg J., Johnson, Chris M., James, Leo C., Fearon, Douglas T.
Published in Proceedings of the National Academy of Sciences - PNAS (16.11.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (16.11.2010)
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Journal Article
CPSF6 defines a conserved capsid interface that modulates HIV-1 replication
Price, Amanda J, Fletcher, Adam J, Schaller, Torsten, Elliott, Tom, Lee, KyeongEun, KewalRamani, Vineet N, Chin, Jason W, Towers, Greg J, James, Leo C
Published in PLoS pathogens (01.08.2012)
Published in PLoS pathogens (01.08.2012)
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Journal Article
HIV-1 with gag processing defects activates cGAS sensing
Sumner, Rebecca P, Blest, Henry, Lin, Meiyin, Maluquer de Motes, Carlos, Towers, Greg J
Published in Retrovirology (23.05.2024)
Published in Retrovirology (23.05.2024)
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Journal Article
HIV integration targeting: a pathway involving Transportin-3 and the nuclear pore protein RanBP2
Ocwieja, Karen E, Brady, Troy L, Ronen, Keshet, Huegel, Alyssa, Roth, Shoshannah L, Schaller, Torsten, James, Leo C, Towers, Greg J, Young, John A T, Chanda, Sumit K, König, Renate, Malani, Nirav, Berry, Charles C, Bushman, Frederic D
Published in PLoS pathogens (01.03.2011)
Published in PLoS pathogens (01.03.2011)
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Journal Article
Selective Inhibition of the Mitochondrial Permeability Transition Pore Protects against Neurodegeneration in Experimental Multiple Sclerosis
Warne, Justin, Pryce, Gareth, Hill, Julia M., Shi, Xiao, Lennerås, Felicia, Puentes, Fabiola, Kip, Maarten, Hilditch, Laura, Walker, Paul, Simone, Michela I., Chan, A.W. Edit, Towers, Greg J., Coker, Alun R., Duchen, Michael R., Szabadkai, Gyorgy, Baker, David, Selwood, David L.
Published in The Journal of biological chemistry (26.02.2016)
Published in The Journal of biological chemistry (26.02.2016)
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Journal Article
The RING-CH ligase K5 antagonizes restriction of KSHV and HIV-1 particle release by mediating ubiquitin-dependent endosomal degradation of tetherin
Pardieu, Claire, Vigan, Raphaël, Wilson, Sam J, Calvi, Alessandra, Zang, Trinity, Bieniasz, Paul, Kellam, Paul, Towers, Greg J, Neil, Stuart J D
Published in PLoS pathogens (01.04.2010)
Published in PLoS pathogens (01.04.2010)
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Journal Article
HIV-1 Vpr antagonizes innate immune activation by targeting karyopherin-mediated NF-κB/IRF3 nuclear transport
Khan, Hataf, Sumner, Rebecca P, Rasaiyaah, Jane, Tan, Choon Ping, Rodriguez-Plata, Maria Teresa, Van Tulleken, Chris, Fink, Douglas, Zuliani-Alvarez, Lorena, Thorne, Lucy, Stirling, David, Milne, Richard Sb, Towers, Greg J
Published in eLife (10.12.2020)
Published in eLife (10.12.2020)
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Journal Article
Hepatitis C virus exploits cyclophilin A to evade PKR
Colpitts, Che C, Ridewood, Sophie, Schneiderman, Bethany, Warne, Justin, Tabata, Keisuke, Ng, Caitlin F, Bartenschlager, Ralf, Selwood, David L, Towers, Greg J
Published in eLife (16.06.2020)
Published in eLife (16.06.2020)
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Journal Article
ChromaClade: combined visualisation of phylogenetic and sequence data
Monit, Christopher, Goldstein, Richard A, Towers, Greg J
Published in BMC ecology and evolution (15.10.2019)
Published in BMC ecology and evolution (15.10.2019)
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Journal Article
Simian immunodeficiency virus envelope glycoprotein counteracts tetherin/BST-2/CD317 by intracellular sequestration
Gupta, Ravindra K, Mlcochova, Petra, Pelchen-Matthews, Annegret, Petit, Sarah J, Mattiuzzo, Giada, Pillay, Deenan, Takeuchi, Yasuhiro, Marsh, Mark, Towers, Greg J
Published in Proceedings of the National Academy of Sciences - PNAS (08.12.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (08.12.2009)
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Journal Article
MxB sensitivity of HIV-1 is determined by a highly variable and dynamic capsid surface
Miles, Richard J, Kerridge, Claire, Hilditch, Laura, Monit, Christopher, Jacques, David A, Towers, Greg J
Published in eLife (17.06.2020)
Published in eLife (17.06.2020)
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Journal Article
Mutation of a single residue renders human tetherin resistant to HIV-1 Vpu-mediated depletion
Gupta, Ravindra K, Hué, Stéphane, Schaller, Torsten, Verschoor, Ernst, Pillay, Deenan, Towers, Greg J
Published in PLoS pathogens (01.05.2009)
Published in PLoS pathogens (01.05.2009)
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Journal Article
HIV-2/SIV Vpx antagonises NF-κB activation by targeting p65
Fink, Douglas L, Cai, James, Whelan, Matthew V X, Monit, Christopher, Maluquer de Motes, Carlos, Towers, Greg J, Sumner, Rebecca P
Published in Retrovirology (24.01.2022)
Published in Retrovirology (24.01.2022)
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