First-in-human phase 1 study of budigalimab, an anti-PD-1 inhibitor, in patients with non-small cell lung cancer and head and neck squamous cell carcinoma
Italiano, Antoine, Cassier, Philippe A., Lin, Chia-Chi, Alanko, Tuomo, Peltola, Katriina J., Gazzah, Anas, Shiah, Her-Shyong, Calvo, Emiliano, Cervantes, Andrés, Roda, Desamparados, Tosi, Diego, Gao, Bo, Millward, Michael, Warburton, Lydia, Tanner, Minna, Englert, Stefan, Lambert, Stacie, Parikh, Apurvasena, Afar, Daniel E., Vosganian, Gregory, Moreno, Victor
Published in Cancer Immunology, Immunotherapy (01.02.2022)
Published in Cancer Immunology, Immunotherapy (01.02.2022)
Get full text
Journal Article
Strategies for clinical development of monoclonal antibodies beyond first-in-man trials: Tested doses and rationale for dose selection
Vinches, Marie, Cuenant, Alice, Alexandre, Marie, Durigova, Anna, Hayaoui, Nadia, Mollevi, Caroline, Gianni, Luca, Tosi, Diego
Published in Journal of clinical oncology (20.05.2015)
Published in Journal of clinical oncology (20.05.2015)
Get full text
Journal Article
Abstract A40: Synergism analysis of dose matrices for combinations of BKM120 (a PI3K inhibitor), MEK162 (a MEK1/2 inhibitor) and chemotherapy in colorectal cancer (CRC) cell lines
Tosi, Diego, Atis, Salima, Mollevi, Caroline, Vie, Nadia, Martineau, Pierre, Gongora, Celine
Published in Clinical cancer research (15.02.2015)
Published in Clinical cancer research (15.02.2015)
Get full text
Journal Article
Abstract 5729: Imiqualines for pancreatic cancer: first-in-class potent and synergistic inhibitors of microtubule polymerisation
Bigot, Kevin, Garambois, Véronique, Vie, Nadia, Bruciamacchie, Marine, Colombo, Pierre-Emmanuel, Tosi, Diego, Patinote, Cindy, Maggipinto, Yann, Bonnet, Pierre-Antoine, Gongora, Céline, Deleuze-Masquefa, Carine, Larbouret, Christel
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Get full text
Journal Article
Abstract CT131: Entrectinib in NTRK -fusion positive ( NTRK -FP) non-small cell lung cancer (NSCLC): Integrated analysis of patients enrolled in three trials (STARTRK-2, STARTRK-1 and ALKA-372-001)
Doebele, Robert, Paz-Ares, Luis, Farago, Anna F., Liu, Stephen V., Chawla, Sant P., Tosi, Diego, Blakely, Collin M., Krauss, John C., Sigal, Darren, Bazhenova, Lyudmila, John, Tom, Besse, Benjamin, Wolf, Jürgen, Seto, Takashi, Chow-Maneval, Edna, Ye, Chenglin, Simmons, Brian, Demetri, George D.
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Get full text
Journal Article
MESOTIP: Phase II multicenter randomized trial evaluating the association of PIPAC and systemic chemotherapy vs. systemic chemotherapy alone as 1st-line treatment of malignant peritoneal mesothelioma
Sgarbura, Olivia, Gourgou, Sophie, Tosi, Diego, Bakrin, Naoual, Bouazza, Nabila, Delaine, Stéphanie, De Forges, Hélène, Pocard, Marc, Quénet, François
Published in Pleura and peritoneum (27.06.2019)
Published in Pleura and peritoneum (27.06.2019)
Get full text
Journal Article
Efficacy of entrectinib in patients (pts) with solid tumors and central nervous system (CNS) metastases: Integrated analysis from three clinical trials
Siena, Salvatore, Doebele, Robert Charles, Shaw, Alice Tsang, Karapetis, Christos Stelios, Tan, Daniel Shao-Weng, Cho, Byoung Chul, Kim, Dong-Wan, Ahn, Myung-Ju, Krebs, Matthew, Goto, Koichi, Garrido Lopez, Pilar, Farago, Anna F., Loong, Herbert H. F., Tosi, Diego, Barve, Minal A., Simmons, Brian P., Ye, Chenglin, Eng, Susan, Drilon, Alexander E.
Published in Journal of clinical oncology (20.05.2019)
Published in Journal of clinical oncology (20.05.2019)
Get full text
Journal Article
B-PRECISE-01 Study: A phase Ib trial of MEN1611, a PI3K Inhibitor, combined with trastuzumab ± fulvestrant for the treatment of HER2-positive advanced or metastatic breast cancer
Piccart-Gebhart, Martine J., Aftimos, Philippe Georges, Duhoux, Francois P., Wildiers, Hans, Isambert, Nicolas, Campone, Mario, Tosi, Diego, Varga, Andrea I., Boni, Valentina, Doger, Bernard, Corbacho, Javier Garcia, Jimenez-Rodriguez, Begona, Ruiz Borrego, Manuel, Saura, Cristina, Arkenau, Hendrik-Tobias, Wardley, Andrew M., Troconiz, Inaki F, Binaschi, Monica, Simonelli, Cecilia, Pellacani, Andrea Ugo
Published in Journal of clinical oncology (20.05.2019)
Published in Journal of clinical oncology (20.05.2019)
Get full text
Journal Article
STING‐ATF3/type I interferon crosstalk: A potential target to improve anti‐tumour immunity in chemotherapy‐treated urothelial carcinoma
Fauvre, Alexandra, Machu, Margot, Merienne, Audrey, Vie, Nadia, Bessede, Thomas, Robin, Mathilde, Garambois, Veronique, Taffoni, Clara, Laguette, Nadine, Gervois‐Segain, Nadine, Jarry, Anne, Labarriere, Nathalie, Allory, Yves, Larbouret, Christel, Gros, Laurent, Tosi, Diego, Solit, David B., Pourquier, Philippe, Houédé, Nadine, Gongora, Celine
Published in Clinical and translational medicine (01.09.2024)
Published in Clinical and translational medicine (01.09.2024)
Get full text
Journal Article
Abstract A147: Synthetic lethality screening reveals ATR as responsible for oxaliplatin resistance in colorectal cancer cells
Combes, Eve, Faria Andrade, Augusto, Tosi, Diego, Coquel, Flavie, Désigaud, Delphine, Garambois, Veronique, Coquelle, Arnaud, Martineau, Pierre, Del Rio, Maguy, Pasero, Philippe, Moreaux, Jerome, Beijersbergen, Roderick, Vie, Nadia, Gongora, Céline
Published in Molecular cancer therapeutics (01.01.2018)
Published in Molecular cancer therapeutics (01.01.2018)
Get full text
Journal Article
Abiraterone acetate in patients with metastatic castration-resistant prostate cancer: long term outcome of the Temporary Authorization for Use programme in France
Houédé, Nadine, Beuzeboc, Philippe, Gourgou, Sophie, Tosi, Diego, Moise, Laura, Gravis, Gwenaëlle, Delva, Remy, Fléchon, Aude, Latorzeff, Igor, Ferrero, Jean-Marc, Oudard, Stéphane, Tartas, Sophie, Laguerre, Brigitte, Topart, Delphine, Roubaud, Guilhem, Agherbi, Hanane, Rebillard, Xavier, Azria, David
Published in BMC cancer (04.04.2015)
Published in BMC cancer (04.04.2015)
Get full text
Journal Article
Guidelines for the definition of time-to-event end points in renal cell cancer clinical trials: results of the DATECAN project
Kramar, A., Negrier, S., Sylvester, R., Joniau, S., Mulders, P., Powles, T., Bex, A., Bonnetain, F., Bossi, A., Bracarda, S., Bukowski, R., Catto, J., Choueiri, T.K., Crabb, S., Eisen, T., El Demery, M., Fitzpatrick, J., Flamand, V., Goebell, P.J., Gravis, G., Houédé, N., Jacqmin, D., Kaplan, R., Malavaud, B., Massard, C., Melichar, B., Mourey, L., Nathan, P., Pasquier, D., Porta, C., Pouessel, D., Quinn, D., Ravaud, A., Rolland, F., Schmidinger, M., Tombal, B., Tosi, D., Vauleon, E., Volpe, A., Wolter, P., Escudier, B., Filleron, T., Kramar, Andrew, Sylvester, Richard, Filleron, Thomas, Negrier, Sylvie, Joniau, Steven, Mulders, Peter, Powles, Thomas, Escudier, Bernard, Bex, Axel, Bonnetain, Franck, Bossi, Alberto, Braccarda, Sergio, Bukowski, Ronald, Catto, James, Choueiri, Toni, Crabb, Simon, Eisen, Tim, El Demery, Mounira, Fitzpatrick, John, Flamand, Vincent, Goebell, Peter J., Gravis, Gwendael, Houédé, Nadine, Jacqmin, Didier, Kaplan, Richard, Malavaud, Bernard, Massard, Christophe, Melichar, Bohuslav, Mourey, Loïc, Nathan, Paul, Pasquier, David, Porta, Camillo, Pouessel, Damien, Quinn, David, Ravaud, Alain, Rolland, Frédéric, Schmidinger, Manuela, Tombal, Bertrand, Tosi, Diego, Vauleon, Elodie, Volpe, Alessandro, Wolter, Pascal
Published in Annals of oncology (01.12.2015)
Published in Annals of oncology (01.12.2015)
Get full text
Journal Article
Abstract PD18-05: MEN1611, a PI3K inhibitor, combined with trastuzumab ± fulvestrant for HER2+/PIK3CA mutant advanced or metastatic breast cancer: updated safety and efficacy results from the ongoing phase 1b study (B-PRECISE-01)
Piccart, Martine, Hennequin, Audrey, Borrego, Manuel Ruiz, Escrivá-de-Romani, Santiago, Williams, Anja, Rodríguez, Begoña Jiménez, Conte, Gianluca Del, Howell, Sacha J., Palleschi, Michela, Simonelli, Matteo, Duhoux, Francois P., Tosi, Diego, Uribe, Bernard Doger de Speville, Gilarranz, Yolanda Jerez, Tassone, Pierfrancesco, Curigliano, Giuseppe, Waters, Simon, Aftimos, Philippe, Wildiers, Hans, Scartoni, Simona, Vallespir, Bartomeu Piza, Shankaraiah, Ram Charan, Grzegorzewski, Krzysztof, Habboubi, Nassir
Published in Cancer research (Chicago, Ill.) (01.03.2023)
Published in Cancer research (Chicago, Ill.) (01.03.2023)
Get full text
Journal Article
Fragile Histidine Triad Gene Inactivation in Lung Cancer: The European Early Lung Cancer Project
Verri, Carla, Roz, Luca, Conte, Davide, Liloglou, Triantafillos, Livio, Anna, Vesin, Aurelien, Fabbri, Alessandra, Andriani, Francesca, Brambilla, Christian, Tavecchio, Luca, Calarco, Giuseppe, Calabro, Elisa, Mancini, Andrea, Tosi, Diego, Bossi, Paolo, Field, John K, Brambilla, Elisabeth, Sozzi, Gabriella, EUELC Consortium
Published in American journal of respiratory and critical care medicine (01.03.2009)
Published in American journal of respiratory and critical care medicine (01.03.2009)
Get full text
Journal Article
GUIP1: a R package for dose escalation strategies in phase I cancer clinical trials
Dinart, D, Fraisse, J, Tosi, D, Mauguen, A, Touraine, C, Gourgou, S, Le Deley, M C, Bellera, C, Mollevi, C
Published in BMC medical informatics and decision making (24.06.2020)
Published in BMC medical informatics and decision making (24.06.2020)
Get full text
Journal Article
Abstract B16: Cetuximab activates Foxo3a via the MAPK p38 to induce apoptosis and reduce cell proliferation in colorectal cancer cells
Marzi, Laetitia, Combes, Eve, VIE, Nadia, Tosi, Diego, Ayrolles-Torro, Adeline, Larbouret, Christel, Denis, Vincent, Linares, Laetitia K., Montagut, Clara, Iglesias, Mar, Martineau, Pierre, Lam, Eric W-F, Del Rio, Maguy, Gongora, Céline
Published in Molecular cancer therapeutics (01.12.2015)
Published in Molecular cancer therapeutics (01.12.2015)
Get full text
Journal Article
Abiraterone acetate in patients with metastatic castration-resistant prostate cancer: Long term outcome of the Temporary Authorization for Use program in France
Houede, Nadine, Beuzeboc, Philippe, Gourgou, Sophie, Tosi, Diego, Moise, Laura, Gravis, Gwenaelle, Delva, Remy, Flechon, Aude, Latorzeff, Igor, Ferrero, Jean-Marc, Oudard, Stephane, Tartas, Sophie, Laguerre, Brigitte, Topart, Delphine, Roubaud, Guilhem, Agherbi, Hanane, Rebillard, Xavier, Azria, David
Published in Journal of clinical oncology (01.03.2015)
Published in Journal of clinical oncology (01.03.2015)
Get full text
Journal Article
Role of cross-talk between IFN-alpha-induced monocyte-derived dendritic cells and NK cells in priming CD8+ T cell responses against human tumor antigens
Tosi, Diego, Valenti, Roberta, Cova, Agata, Sovena, Gloria, Huber, Veronica, Pilla, Lorenzo, Arienti, Flavio, Belardelli, Filippo, Parmiani, Giorgio, Rivoltini, Licia
Published in The Journal of immunology (1950) (01.05.2004)
Published in The Journal of immunology (1950) (01.05.2004)
Get full text
Journal Article
A phase II trial of vaccination with autologous, tumor-derived heat-shock protein peptide complexes Gp96, in combination with GM-CSF and interferon-α in metastatic melanoma patients
PILLA, Lorenzo, PATUZZO, Roberto, TOSI, Diego, ARIENTI, Flavio, COVA, Agata, SOVENA, Gloria, PIRIS, Adriano, NONAKA, Daisuke, BERSANI, Ilaria, DI FLORIO, Annabella, LUIGI, Mariani, SRIVASTAVA, Pramod K, RIVOLTINI, Licia, HOOS, Axel, SANTINAMI, Mario, PARMIANI, Giorgio, MAIO, Michele, PENNACCHIOLI, Elisabetta, LAMAJ, Elda, MAURICHI, Andrea, MASSARUT, Samuele, MARCHIANO, Alfonso, SANTANTONIO, Cristina
Published in Cancer Immunology, Immunotherapy (01.08.2006)
Published in Cancer Immunology, Immunotherapy (01.08.2006)
Get full text
Journal Article