Reduced functional deficits, neuroinflammation, and secondary tissue damage after treatment of stroke by nonerythropoietic erythropoietin derivatives
Villa, Pia, van Beek, Johan, Larsen, Anna Kirstine, Gerwien, Jens, Christensen, Søren, Cerami, Anthony, Brines, Michael, Leist, Marcel, Ghezzi, Pietro, Torup, Lars
Published in Journal of cerebral blood flow and metabolism (01.03.2007)
Published in Journal of cerebral blood flow and metabolism (01.03.2007)
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The Sonic Hedgehog Pathway Mediates Carbamylated Erythropoietin-enhanced Proliferation and Differentiation of Adult Neural Progenitor Cells
Wang, Lei, Zhang, Zheng Gang, Gregg, Sara R., Zhang, Rui Lan, Jiao, Zhongxian, LeTourneau, Yvonne, Liu, Xianshuang, Feng, Yifan, Gerwien, Jens, Torup, Lars, Leist, Marcel, Noguchi, Constance Tom, Chen, Zhi-Yong, Chopp, Michael
Published in The Journal of biological chemistry (02.11.2007)
Published in The Journal of biological chemistry (02.11.2007)
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Asialoerythropoietin Is a Nonerythropoietic Cytokine with Broad Neuroprotective Activity in vivo
Erbayraktar, Serhat, Grasso, Giovanni, Sfacteria, Alessandra, Xie, Qiao-wen, Coleman, Thomas, Kreilgaard, Mads, Torup, Lars, Sager, Thomas, Erbayraktar, Zubeyde, Gokmen, Necati, Yilmaz, Osman, Ghezzi, Pietro, Villa, Pia, Fratelli, Maddalena, Casagrande, Simona, Leist, Marcel, Helboe, Lone, Gerwein, Jens, Christensen, Søren, Geist, Marie Aavang, Pedersen, Lars Østergaard, Cerami-Hand, Carla, Wuerth, Jean-Paul, Cerami, Anthony, Brines, Michael
Published in Proceedings of the National Academy of Sciences - PNAS (27.05.2003)
Published in Proceedings of the National Academy of Sciences - PNAS (27.05.2003)
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High-dose erythropoietin alters platelet reactivity and bleeding time in rodents in contrast to the neuroprotective variant carbamyl-erythropoietin (CEPO)
Kirkeby, Agnete, Torup, Lars, Bochsen, Louise, Kjalke, Marianne, Abel, Kristin, Theilgaard-Monch, Kim, Johansson, Pär I, Bjørn, Søren E, Gerwien, Jens, Leist, Marcel
Published in Thrombosis and haemostasis (01.04.2008)
Published in Thrombosis and haemostasis (01.04.2008)
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Long-term efficacy, tolerability and safety of nalmefene as-needed in patients with alcohol dependence: A 1-year, randomised controlled study
van den Brink, Wim, Sørensen, Per, Torup, Lars, Mann, Karl, Gual, Antoni
Published in Journal of psychopharmacology (Oxford) (01.08.2014)
Published in Journal of psychopharmacology (Oxford) (01.08.2014)
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Nalmefene for the management of alcohol dependence: review on its pharmacology, mechanism of action and meta-analysis on its clinical efficacy
Mann, Karl, Torup, Lars, Sørensen, Per, Gual, Antoni, Swift, Robert, Walker, Brendan, van den Brink, Wim
Published in European neuropsychopharmacology (01.12.2016)
Published in European neuropsychopharmacology (01.12.2016)
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Efficacy of As-Needed Nalmefene in Alcohol-Dependent Patients with at Least a High Drinking Risk Level: Results from a Subgroup Analysis of Two Randomized Controlled 6-Month Studies
VAN DEN BRINK, Wim, AUBIN, Henri-Jean, BLADSTRÖM, Anna, TORUP, Lars, GUAL, Antoni, MANN, Karl
Published in Alcohol and alcoholism (Oxford) (01.09.2013)
Published in Alcohol and alcoholism (Oxford) (01.09.2013)
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Methods to Analyze Treatment Effects in the Presence of Missing Data for a Continuous Heavy Drinking Outcome Measure When Participants Drop Out from Treatment in Alcohol Clinical Trials
Witkiewitz, Katie, Falk, Daniel E., Kranzler, Henry R., Litten, Raye Z., Hallgren, Kevin A., O'Malley, Stephanie S., Anton, Raymond F.
Published in Alcoholism, clinical and experimental research (01.11.2014)
Published in Alcoholism, clinical and experimental research (01.11.2014)
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Journal Article
Derivatives of Erythropoietin That Are Tissue Protective but Not Erythropoietic
Leist, Marcel, Ghezzi, Pietro, Grasso, Giovanni, Bianchi, Roberto, Villa, Pia, Fratelli, Maddalena, Savino, Costanza, Bianchi, Marina, Nielsen, Jacob, Gerwien, Jens, Kallunki, Pekka, Larsen, Anna Kirstine, Helboe, Lone, Christensen, Søren, Pedersen, Lars O., Nielsen, Mette, Torup, Lars, Sager, Thomas, Sfacteria, Alessandra, Erbayraktar, Serhat, Erbayraktar, Zubeyde, Gokmen, Necati, Yilmaz, Osman, Cerami-Hand, Carla, Xie, Qiao-wen, Coleman, Thomas, Cerami, Anthony, Brines, Michael
Published in Science (American Association for the Advancement of Science) (09.07.2004)
Published in Science (American Association for the Advancement of Science) (09.07.2004)
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Nonhematopoietic erythropoietin derivatives prevent motoneuron degeneration in vitro and in vivo
Mennini, Tiziana, De Paola, Massimiliano, Bigini, Paolo, Mastrotto, Cristina, Fumagalli, Elena, Barbera, Sara, Mengozzi, Manuela, Viviani, Barbara, Corsini, Emanuela, Marinovich, Marina, Torup, Lars, Van Beek, Johan, Leist, Marcel, Brines, Michael, Cerami, Antony, Ghezzi, Pietro
Published in Molecular medicine (Cambridge, Mass.) (01.07.2006)
Published in Molecular medicine (Cambridge, Mass.) (01.07.2006)
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Discovery of Phosphoric Acid Mono-{2-[( E / Z )-4-(3,3-dimethyl-butyrylamino)-3,5-difluoro-benzoylimino]-thiazol-3-ylmethyl} Ester (Lu AA47070): A Phosphonooxymethylene Prodrug of a Potent and Selective hA 2A Receptor Antagonist
Sams, Anette G., Mikkelsen, Gitte K., Larsen, Mogens, Langgård, Morten, Howells, Mark E., Schrøder, Tenna J., Brennum, Lise T., Torup, Lars, Jørgensen, Erling B., Bundgaard, Christoffer, Kreilgård, Mads, Bang-Andersen, Benny
Published in Journal of medicinal chemistry (10.02.2011)
Published in Journal of medicinal chemistry (10.02.2011)
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Discovery of Phosphoric Acid Mono-{2-[(E/Z)-4-(3,3-dimethyl-butyrylamino)-3,5-difluorobenzoylimino]-thiazol-3-ylmethyl} Ester (Lu AA47070): A Phosphonooxymethylene Prodrug of a Potent and Selective hA(2A) Receptor Antagonist
Sams, Anette G., Mikkelsen, Gitte K., Larsen, Mogens, Langgard, Morten, Howells, Mark E., Schroder, Tenna J., Brennum, Lise T., Torup, Lars, Jorgensen, Erling B., Bundgaard, Christoffer, Kreilgard, Mads, Bang-Andersen, Benny
Published in Journal of medicinal chemistry (10.02.2011)
Published in Journal of medicinal chemistry (10.02.2011)
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Cumulative proportion of responders analysis (CPRA) as a tool to assess treatment outcome in alcohol clinical trials
Falk, Daniel E, Litten, Raye Z, Anton, Raymond F, Kranzler, Henry R, Johnson, Bankole A
Published in Journal of studies on alcohol and drugs (01.03.2014)
Published in Journal of studies on alcohol and drugs (01.03.2014)
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Hit-to-lead optimization of a series of carboxamides of ethyl 2-amino-4-phenylthiazole-5-carboxylates as novel adenosine A2A receptor antagonists
GRAVEN SAMS, Anette, MIKKELSEN, Gitte Kobberøe, LARSEN, Mogens, TORUP, Lars, BRENNUM, Lise Tottrup, SCHRØDER, Tenna Juul, BANG-ANDERSEN, Benny
Published in Bioorganic & medicinal chemistry letters (01.09.2010)
Published in Bioorganic & medicinal chemistry letters (01.09.2010)
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Hit-to-lead optimization of a series of carboxamides of ethyl 2-amino-4-phenylthiazole-5-carboxylates as novel adenosine A 2A receptor antagonists
Sams, Anette Graven, Mikkelsen, Gitte Kobberøe, Larsen, Mogens, Torup, Lars, Brennum, Lise Tøttrup, Schrøder, Tenna Juul, Bang-Andersen, Benny
Published in Bioorganic & medicinal chemistry letters (2010)
Published in Bioorganic & medicinal chemistry letters (2010)
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