Structural basis for PPAR partial or full activation revealed by a novel ligand binding mode
Capelli, Davide, Cerchia, Carmen, Montanari, Roberta, Loiodice, Fulvio, Tortorella, Paolo, Laghezza, Antonio, Cervoni, Laura, Pochetti, Giorgio, Lavecchia, Antonio
Published in Scientific reports (06.10.2016)
Published in Scientific reports (06.10.2016)
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Journal Article
Bone-Seeking Matrix Metalloproteinase-2 Inhibitors Prevent Bone Metastatic Breast Cancer Growth
Tauro, Marilena, Shay, Gemma, Sansil, Samer S, Laghezza, Antonio, Tortorella, Paolo, Neuger, Anthony M, Soliman, Hatem, Lynch, Conor C
Published in Molecular cancer therapeutics (01.03.2017)
Published in Molecular cancer therapeutics (01.03.2017)
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Journal Article
A New Series of Aryloxyacetic Acids Endowed with Multi-Target Activity towards Peroxisome Proliferator-Activated Receptors (PPARs), Fatty Acid Amide Hydrolase (FAAH), and Acetylcholinesterase (AChE)
Leuci, Rosalba, Brunetti, Leonardo, Laghezza, Antonio, Piemontese, Luca, Carrieri, Antonio, Pisani, Leonardo, Tortorella, Paolo, Catto, Marco, Loiodice, Fulvio
Published in Molecules (Basel, Switzerland) (31.01.2022)
Published in Molecules (Basel, Switzerland) (31.01.2022)
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Journal Article
Beyond the Canonical Endocannabinoid System. A Screening of PPAR Ligands as FAAH Inhibitors
Brunetti, Leonardo, Carrieri, Antonio, Piemontese, Luca, Tortorella, Paolo, Loiodice, Fulvio, Laghezza, Antonio
Published in International journal of molecular sciences (01.10.2020)
Published in International journal of molecular sciences (01.10.2020)
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Journal Article
Clinical Features and Complications of the HLA-B27-associated Acute Anterior Uveitis: A Metanalysis
D'Ambrosio, Enzo Maria, La Cava, Maurizio, Tortorella, Paolo, Gharbiya, Magda, Campanella, Michelangelo, Iannetti, Ludovico
Published in Seminars in ophthalmology (02.11.2017)
Published in Seminars in ophthalmology (02.11.2017)
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Journal Article
Combining fatty acid amide hydrolase (FAAH) inhibition with peroxisome proliferator-activated receptor (PPAR) activation: a new potential multi-target therapeutic strategy for the treatment of Alzheimer's disease
Brunetti, Leonardo, Laghezza, Antonio, Loiodice, Fulvio, Tortorella, Paolo, Piemontese, Luca
Published in Neural regeneration research (01.01.2020)
Published in Neural regeneration research (01.01.2020)
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Journal Article
Phosphonate Emerging Zinc Binding Group in Matrix Metalloproteinase Inhibitors
Campestre, Cristina, Agamennone, Mariangela, Tauro, Marilena, Tortorella, Paolo
Published in Current drug targets (01.01.2015)
Published in Current drug targets (01.01.2015)
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Journal Article
(2-Aminobenzothiazole)-Methyl-1,1-Bisphosphonic Acids: Targeting Matrix Metalloproteinase 13 Inhibition to the Bone
Laghezza, Antonio, Piemontese, Luca, Brunetti, Leonardo, Caradonna, Alessia, Agamennone, Mariangela, Loiodice, Fulvio, Tortorella, Paolo
Published in Pharmaceuticals (Basel, Switzerland) (24.01.2021)
Published in Pharmaceuticals (Basel, Switzerland) (24.01.2021)
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Journal Article
Inhibition of bacterial and human zinc-metalloproteases by bisphosphonate- and catechol-containing compounds
Rahman, Fatema, Nguyen, Tra-Mi, Adekoya, Olayiwola A., Campestre, Cristina, Tortorella, Paolo, Sylte, Ingebrigt, Winberg, Jan-Olof
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2021)
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2021)
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Journal Article
Management of Uveitis-Related Choroidal Neovascularization: From the Pathogenesis to the Therapy
D’Ambrosio, Enzo, Tortorella, Paolo, Iannetti, Ludovico
Published in Journal of Ophthalmology (01.01.2014)
Published in Journal of Ophthalmology (01.01.2014)
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Journal Article
Derivatives of Tenuazonic Acid as Potential New Multi-Target Anti-Alzheimer's Disease Agents
Poliseno, Viviana, Chaves, Sílvia, Brunetti, Leonardo, Loiodice, Fulvio, Carrieri, Antonio, Laghezza, Antonio, Tortorella, Paolo, Magalhães, João D, Cardoso, Sandra M, Santos, M Amélia, Piemontese, Luca
Published in Biomolecules (Basel, Switzerland) (15.01.2021)
Published in Biomolecules (Basel, Switzerland) (15.01.2021)
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Journal Article
Novel Phenothiazine/Donepezil-like Hybrids Endowed with Antioxidant Activity for a Multi-Target Approach to the Therapy of Alzheimer’s Disease
Carocci, Alessia, Barbarossa, Alexia, Leuci, Rosalba, Carrieri, Antonio, Brunetti, Leonardo, Laghezza, Antonio, Catto, Marco, Limongelli, Francesco, Chaves, Sílvia, Tortorella, Paolo, Altomare, Cosimo Damiano, Santos, Maria Amélia, Loiodice, Fulvio, Piemontese, Luca
Published in Antioxidants (23.08.2022)
Published in Antioxidants (23.08.2022)
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Journal Article
Seeking for Non-Zinc-Binding MMP-2 Inhibitors: Synthesis, Biological Evaluation and Molecular Modelling Studies
Ammazzalorso, Alessandra, De Filippis, Barbara, Campestre, Cristina, Laghezza, Antonio, Marrone, Alessandro, Amoroso, Rosa, Tortorella, Paolo, Agamennone, Mariangela
Published in International journal of molecular sciences (01.10.2016)
Published in International journal of molecular sciences (01.10.2016)
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Journal Article
Het(aryl)isatin to het(aryl)aminoindoline scaffold hopping: A route to selective inhibitors of matrix metalloproteinases
Ivanov, Vladimir N., Agamennone, Mariangela, Iusupov, Ildar R., Laghezza, Antonio, Novoselov, Anton M., Manasova, Ekaterina V., Altieri, Andrea, Tortorella, Paolo, Shtil, Alexander A., Kurkin, Alexander V.
Published in Arabian journal of chemistry (01.01.2022)
Published in Arabian journal of chemistry (01.01.2022)
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Journal Article
An Effective Virtual Screening Protocol To Identify Promising p53–MDM2 Inhibitors
Tortorella, Paolo, Laghezza, Antonio, Durante, Milena, Gomez-Monterrey, Isabel, Bertamino, Alessia, Campiglia, Pietro, Loiodice, Fulvio, Daniele, Simona, Martini, Claudia, Agamennone, Mariangela
Published in Journal of chemical information and modeling (27.06.2016)
Published in Journal of chemical information and modeling (27.06.2016)
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Journal Article
Bone-Seeking Matrix Metalloproteinase Inhibitors for the Treatment of Skeletal Malignancy
Laghezza, Antonio, Piemontese, Luca, Brunetti, Leonardo, Caradonna, Alessia, Agamennone, Mariangela, Di Pizio, Antonella, Pochetti, Giorgio, Montanari, Roberta, Capelli, Davide, Tauro, Marilena, Loiodice, Fulvio, Tortorella, Paolo
Published in Pharmaceuticals (Basel, Switzerland) (01.06.2020)
Published in Pharmaceuticals (Basel, Switzerland) (01.06.2020)
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Journal Article