Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing
Siddiqi, Farah H., Menzies, Fiona M., Lopez, Ana, Stamatakou, Eleanna, Karabiyik, Cansu, Ureshino, Rodrigo, Ricketts, Thomas, Jimenez-Sanchez, Maria, Esteban, Miguel Angel, Lai, Liangxue, Tortorella, Micky D., Luo, Zhiwei, Liu, Hao, Metzakopian, Emmanouil, Fernandes, Hugo J. R., Bassett, Andrew, Karran, Eric, Miller, Bruce L., Fleming, Angeleen, Rubinsztein, David C.
Published in Nature communications (18.04.2019)
Published in Nature communications (18.04.2019)
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Rescue of ATP7B function in hepatocyte-like cells from Wilson's disease induced pluripotent stem cells using gene therapy or the chaperone drug curcumin
Zhang, Shiqiang, Chen, Shen, Li, Wen, Guo, Xiangpeng, Zhao, Ping, Xu, Jianyong, Chen, Yan, Pan, Qiong, Liu, Xiaorong, Zychlinski, Daniela, Lu, Hai, Tortorella, Micky D., Schambach, Axel, Wang, Yan, Pei, Duanqing, Esteban, Miguel A.
Published in Human molecular genetics (15.08.2011)
Published in Human molecular genetics (15.08.2011)
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Long Non-Coding RNA Malat1 Increases the Rescuing Effect of Quercetin on TNFα-Impaired Bone Marrow Stem Cell Osteogenesis and Ovariectomy-Induced Osteoporosis
Feng, Lu, Yang, Zhengmeng, Hou, Nan, Wang, Ming, Lu, Xuan, Li, Yucong, Wang, Haixing, Wang, Yaofeng, Bai, Shanshan, Zhang, Xiaoting, Lin, Yuejun, Yan, Xu, Lin, Sien, Tortorella, Micky D, Li, Gang
Published in International journal of molecular sciences (01.03.2023)
Published in International journal of molecular sciences (01.03.2023)
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Malat1 attenuated the rescuing effects of docosahexaenoic acid on osteoarthritis treatment via repressing its chondroprotective and chondrogenesis activities
Feng, Lu, Yang, Zhengmeng, Li, Yucong, Hou, Nan, Yang, Boguang, Lu, Xuan, Bai, Shanshan, Wang, Ming, Zhang, Xiaoting, Wang, Haixing, Wang, Yaofeng, Tortorella, Micky D., Li, Gang
Published in Biomedicine & pharmacotherapy (01.10.2022)
Published in Biomedicine & pharmacotherapy (01.10.2022)
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Desirable Properties for 3rd Generation Cyclooxygenase-2 Inhibitors
Tortorella, Micky D, Zhang, Yanmei, Talley, John
Published in Mini reviews in medicinal chemistry (01.01.2016)
Published in Mini reviews in medicinal chemistry (01.01.2016)
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Exclusion of HDAC1/2 complexes by oncogenic nuclear condensates
Kuang, Junqi, Li, Pengli, Zhai, Ziwei, Fan, Yixin, Xu, HuaiYuan, Zhao, Chengchen, Li, Wei, Li, Xiaoxi, Liang, Zechuan, Huang, Tao, Qin, Yue, Gao, Huiru, Ma, Zhaoyi, Liu, Dong, Zhong, Guifa, Wang, Bo, Liu, Jing, Wang, Jin, Tortorella, Micky D, Liao, Baojian, Pei, Duanqing
Published in Molecular cancer (27.04.2024)
Published in Molecular cancer (27.04.2024)
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DANCR Mediates the Rescuing Effects of Sesamin on Postmenopausal Osteoporosis Treatment via Orchestrating Osteogenesis and Osteoclastogenesis
Yang, Zhengmeng, Feng, Lu, Wang, Haixing, Li, Yucong, Lo, Jessica Hiu Tung, Zhang, Xiaoting, Lu, Xuan, Wang, Yaofeng, Lin, Sien, Tortorella, Micky D, Li, Gang
Published in Nutrients (13.12.2021)
Published in Nutrients (13.12.2021)
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Cholecystokinin B receptor agonists alleviates anterograde amnesia in cholecystokinin-deficient and aged Alzheimer's disease mice
Zhang, Nan, Sui, Yixuan, Jendrichovsky, Peter, Feng, Hemin, Shi, Heng, Zhang, Xu, Xu, Shenghui, Sun, Wenjian, Zhang, Huatang, Chen, Xi, Tortorella, Micky D, He, Jufang
Published in Alzheimer's research & therapy (15.05.2024)
Published in Alzheimer's research & therapy (15.05.2024)
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Sesamin Promotes Osteoporotic Fracture Healing by Activating Chondrogenesis and Angiogenesis Pathways
Yang, Zhengmeng, Feng, Lu, Wang, Ming, Li, Yucong, Bai, Shanshan, Lu, Xuan, Wang, Haixing, Zhang, Xiaoting, Wang, Yaofeng, Lin, Sien, Tortorella, Micky D, Li, Gang
Published in Nutrients (18.05.2022)
Published in Nutrients (18.05.2022)
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O-alg-THAM/gel hydrogels functionalized with engineered microspheres based on mesenchymal stem cell secretion recruit endogenous stem cells for cartilage repair
Li, Yucong, Li, Linlong, Wang, Ming, Yang, Boguang, Huang, Baozhen, Bai, Shanshan, Zhang, Xiaoting, Hou, Nan, Wang, Haixing, Yang, Zhengmeng, Tang, Chong, Li, Ye, Yuk-Wai Lee, Wayne, Feng, Lu, Tortorella, Micky D., Li, Gang
Published in Bioactive materials (01.10.2023)
Published in Bioactive materials (01.10.2023)
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Author Correction: Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing
Siddiqi, Farah H., Menzies, Fiona M., Lopez, Ana, Stamatakou, Eleanna, Karabiyik, Cansu, Ureshino, Rodrigo, Ricketts, Thomas, Jimenez-Sanchez, Maria, Esteban, Miguel Angel, Lai, Liangxue, Tortorella, Micky D., Luo, Zhiwei, Liu, Hao, Metzakopian, Emmanouil, Fernandes, Hugo J. R., Bassett, Andrew, Karran, Eric, Miller, Bruce L., Fleming, Angeleen, Rubinsztein, David C.
Published in Nature communications (04.06.2019)
Published in Nature communications (04.06.2019)
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Low-Dose Staphylococcal Enterotoxin C2 Mutant Maintains Bone Homeostasis via Regulating Crosstalk between Bone Formation and Host T-Cell Effector Immunity
Wang, Haixing, Lin, Sien, Feng, Lu, Huang, Baozhen, Lu, Xuan, Yang, Zhengmeng, Jiang, Zhaowei, Li, Yu-Cong, Zhang, Xiaoting, Wang, Ming, Wang, Bin, Kong, Lingchi, Pan, Qi, Bai, Shanshan, Li, Yuan, Yang, Yongkang, Lee, Wayne Yuk Wai, Currie, Peter D, Lin, Changshuang, Jiang, Yanfu, Chen, Juyu, Tortorella, Micky D, Li, Hongyi, Li, Gang
Published in Advanced science (01.10.2023)
Published in Advanced science (01.10.2023)
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Aggrecan Protects Cartilage Collagen from Proteolytic Cleavage
Pratta, Michael A., Yao, Wenqing, Decicco, Carl, Tortorella, Micky D., Liu, Riu-Qin, Copeland, Robert A., Magolda, Ronald, Newton, Robert C., Trzaskos, James M., Arner, Elizabeth C.
Published in The Journal of biological chemistry (14.11.2003)
Published in The Journal of biological chemistry (14.11.2003)
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Proprotein convertase activation of aggrecanases in cartilage in situ
Malfait, Anne-Marie, Arner, Elizabeth C., Song, Ruo-Hua, Alston, James T., Markosyan, Stella, Staten, Nicholas, Yang, Zhiyong, Griggs, David W., Tortorella, Micky D.
Published in Archives of biochemistry and biophysics (01.10.2008)
Published in Archives of biochemistry and biophysics (01.10.2008)
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Structural and Inhibition Analysis Reveals the Mechanism of Selectivity of a Series of Aggrecanase Inhibitors
Tortorella, Micky D., Tomasselli, Alfredo G., Mathis, Karl J., Schnute, Mark E., Woodard, Scott S., Munie, Grace, Williams, Jennifer M., Caspers, Nicole, Wittwer, Arthur J., Malfait, Anne-Marie, Shieh, Huey-Sheng
Published in The Journal of biological chemistry (04.09.2009)
Published in The Journal of biological chemistry (04.09.2009)
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High Resolution Crystal Structure of the Catalytic Domain of ADAMTS-5 (Aggrecanase-2)
Shieh, Huey-Sheng, Mathis, Karl J., Williams, Jennifer M., Hills, Robert L., Wiese, Joe F., Benson, Timothy E., Kiefer, James R., Marino, Margaret H., Carroll, Jeffery N., Leone, Joseph W., Malfait, Anne-Marie, Arner, Elizabeth C., Tortorella, Micky D., Tomasselli, Alfredo
Published in The Journal of biological chemistry (18.01.2008)
Published in The Journal of biological chemistry (18.01.2008)
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The "elusive DMOAD": Aggrecanase inhibition from laboratory to clinic
Malfait, Anne-Marie, Tortorella, Micky D
Published in Clinical and experimental rheumatology (01.09.2019)
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Published in Clinical and experimental rheumatology (01.09.2019)
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Identification of an ADAMTS-4 Cleavage Motif Using Phage Display Leads to the Development of Fluorogenic Peptide Substrates and Reveals Matrilin-3 as a Novel Substrate
Hills, Robert, Mazzarella, Richard, Fok, Kam, Liu, Min, Nemirovskiy, Olga, Leone, Joseph, Zack, Marc D., Arner, Elizabeth C., Viswanathan, Malini, Abujoub, Aida, Muruganandam, Arumugam, Sexton, Daniel J., Bassill, Gary J., Sato, Aaron K., Malfait, Anne-Marie, Tortorella, Micky D.
Published in The Journal of biological chemistry (13.04.2007)
Published in The Journal of biological chemistry (13.04.2007)
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NCoR/SMRT co-repressors cooperate with c-MYC to create an epigenetic barrier to somatic cell reprogramming
Zhuang, Qiang, Li, Wenjuan, Benda, Christina, Huang, Zhijian, Ahmed, Tanveer, Liu, Ping, Guo, Xiangpeng, Ibañez, David P., Luo, Zhiwei, Zhang, Meng, Abdul, Mazid Md, Yang, Zhongzhou, Yang, Jiayin, Huang, Yinghua, Zhang, Hui, Huang, Dehao, Zhou, Jianguo, Zhong, Xiaofen, Zhu, Xihua, Fu, Xiuling, Fan, Wenxia, Liu, Yulin, Xu, Yan, Ward, Carl, Khan, Muhammad Jadoon, Kanwal, Shahzina, Mirza, Bushra, Tortorella, Micky D., Tse, Hung-Fat, Chen, Jiayu, Qin, Baoming, Bao, Xichen, Gao, Shaorong, Hutchins, Andrew P., Esteban, Miguel A.
Published in Nature cell biology (01.04.2018)
Published in Nature cell biology (01.04.2018)
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