Inhibition of overactivated p38 MAPK can restore hematopoiesis in myelodysplastic syndrome progenitors
Navas, Tony A., Mohindru, Mani, Estes, Myka, Ma, Jing Ying, Sokol, Lubomir, Pahanish, Perry, Parmar, Simrit, Haghnazari, Edwin, Zhou, Li, Collins, Robert, Kerr, Irene, Nguyen, Aaron N., Xu, Yin, Platanias, Leonidas C., List, Alan A., Higgins, Linda S., Verma, Amit
Published in Blood (15.12.2006)
Published in Blood (15.12.2006)
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Journal Article
Inhibition of the TGF-β receptor I kinase promotes hematopoiesis in MDS
Zhou, Li, Nguyen, Aaron N., Sohal, Davendra, Ying Ma, Jing, Pahanish, Perry, Gundabolu, Krishna, Hayman, Josh, Chubak, Adam, Mo, Yongkai, Bhagat, Tushar D., Das, Bhaskar, Kapoun, Ann M., Navas, Tony A., Parmar, Simrit, Kambhampati, Suman, Pellagatti, Andrea, Braunchweig, Ira, Zhang, Ying, Wickrema, Amittha, Medicherla, Satyanarayana, Boultwood, Jacqueline, Platanias, Leonidas C., Higgins, Linda S., List, Alan F., Bitzer, Markus, Verma, Amit
Published in Blood (15.10.2008)
Published in Blood (15.10.2008)
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Normalizing the bone marrow microenvironment with p38 inhibitor reduces multiple myeloma cell proliferation and adhesion and suppresses osteoclast formation
Nguyen, Aaron N., Stebbins, Elizabeth G., Henson, Margaret, O'Young, Gilbert, Choi, Sun J., Quon, Diana, Damm, Debby, Reddy, Mamatha, Ma, Jing Y., Haghnazari, Edwin, Kapoun, Ann M., Medicherla, Satyanarayana, Protter, Andy, Schreiner, George F., Kurihara, Noriyoshi, Anderson, Judy, Roodman, G. David, Navas, Tony A., Higgins, Linda S.
Published in Experimental cell research (10.06.2006)
Published in Experimental cell research (10.06.2006)
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Journal Article
RIP2 Is a Raf1-activated Mitogen-activated Protein Kinase Kinase
Navas, Tony A., Baldwin, Daryl T., Stewart, Timothy A.
Published in The Journal of biological chemistry (19.11.1999)
Published in The Journal of biological chemistry (19.11.1999)
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Preventive and therapeutic potential of p38 alpha-selective mitogen-activated protein kinase inhibitor in nonobese diabetic mice with type 1 diabetes
Medicherla, Satyanarayana, Protter, Andrew A, Ma, Jing Ying, Mangadu, Ruban, Almirez, Ramona, Koppelman, Bruce, Kerr, Irene, Navas, Tony A, Movius, Fabiola, Reddy, Mamatha, Liu, Yu-Wang, Luedtke, Gregory, Perumattam, John, Mavunkel, Babu, Dugar, Sundeep, Schreiner, George F
Published in The Journal of pharmacology and experimental therapeutics (01.07.2006)
Published in The Journal of pharmacology and experimental therapeutics (01.07.2006)
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Journal Article
p38 alpha -Selective MAP Kinase Inhibitor Reduces Tumor Growth in Mouse Xenograft Models of Multiple Myeloma
Medicherla, S, Reddy, M, Ma, J Y, Navas, T A, Li, L, Nguyen, AN, Kerr, I, Hanjarappa, N, Protter, A A, Higgins, L S
Published in Anticancer research (01.11.2008)
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Published in Anticancer research (01.11.2008)
Journal Article
p38alpha-selective MAP kinase inhibitor reduces tumor growth in mouse xenograft models of multiple myeloma
Medicherla, Satyanarayana, Reddy, Mamatha, Ying, Jing, Navas, Tony A, Li, Lingyun, Nguyen, Aaron N, Kerr, Irene, Hanjarappa, Nirupama, Protter, Andrew A, Higgins, Linda S
Published in Anticancer research (01.11.2008)
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Published in Anticancer research (01.11.2008)
Journal Article
SCIO-469, a Potent and Selective Inhibitor of the p38a MAPK, Inhibits TNFa-Induced Adhesion of Multiple Myeloma Cells to Bone Marrow Stromal Cells Via Downregulation of Chemokines CXCL10/IP-10 and CCL8
Nguyen, Aaron N., Young, Gilbert O', Quon, Diana, Damm, Debby, Kapoun, Ann M., Higgins, Linda S., Navas, Tony A.
Published in Blood (16.11.2005)
Published in Blood (16.11.2005)
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Journal Article
p38α-Selective MAP Kinase Inhibitor Reduces Tumor Growth in Mouse Xenograft Models of Multiple Myeloma
SATYANARAYANA MEDICHERLA, MAMATHA REDDY, JING YING MA, TONY A. NAVAS, LINGYUN LI, AARON N. NGUYEN, IRENE KERR, NIRUPAMA HANJARAPPA, ANDREW A. PROTTER, LINDA S. HIGGINS
Published in Anticancer research (01.11.2008)
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Published in Anticancer research (01.11.2008)
Journal Article
P38a-Selective MAP Kinase Inhibitor Reduces Tumor Growth in Mouse Xenograft Models of Multiple Myeloma
MEDICHERLA, Satyanarayana, REDDY, Mamatha, JING YING MA, NAVAS, Tony A, LINGYUN LI, NGUYEN, Aaron N, KERR, Irene, HANJARAPPA, Nirupama, PROTTER, Andrew A, HIGGINS, Linda S
Published in Anticancer research (2008)
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Published in Anticancer research (2008)
Journal Article
SD-208, a Novel Transforming Growth Factor Beta Receptor I Kinase Inhibitor, Can Stimulate Hematopoiesis in Myelodysplastic Syndrome Progenitors
Verma, Amit, Navas, Tony A., Ying, Jing, Nguyen, Aaron N., Pahanish, Perry, Seetharam, Mahesh, Kerr, Irene, Collins, Robert, Kim, Mimi, Mohindru, Mani, Higgins, Linda S.
Published in Blood (16.11.2005)
Published in Blood (16.11.2005)
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Journal Article
Inhibition of the TGF-β receptor I kinase promotes hematopoiesis in MDS. Commentary
ABBOUD, Camille N, LI ZHOU, BHAGAT, Tushar D, DAS, Bhaskar, KAPOUN, Ann M, NAVAS, Tony A, PARMAR, Simrit, KAMBHAMPATI, Suman, PELLAGATTI, Andrea, BRAUNCHWEIG, Ira, YING ZHANG, WICKREMA, Amittha, NGUYEN, Aaron N, MEDICHERLA, Satyanarayana, BOULTWOOD, Jacqueline, PLATANIAS, Leonidas C, HIGGINS, Linda S, LIST, Alan F, BITZER, Markus, VERMA, Amit, SOHAL, Davendra, JING YING MA, PAHANISH, Perry, GUNDABOLU, Krishna, HAYMAN, Josh, CHUBAK, Adam, YONGKAI MO
Published in Blood (2008)
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Published in Blood (2008)
Journal Article
Preventive and Therapeutic Potential of p38α-Selective Mitogen-Activated Protein Kinase Inhibitor in Nonobese Diabetic Mice with Type 1 Diabetes
Satyanarayana Medicherla, Andrew A. Protter, Jing Ying Ma, Ruban Mangadu, Ramona Almirez, Bruce Koppelman, Irene Kerr, Tony A. Navas, Fabiola Movius, Mamatha Reddy, Yu-Wang Liu, Gregory Luedtke, John Perumattam, Babu Mavunkel, Sundeep Dugar, George F. Schreiner
Published in The Journal of pharmacology and experimental therapeutics (01.07.2006)
Published in The Journal of pharmacology and experimental therapeutics (01.07.2006)
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Journal Article
Inhibition of p38 MAPK by SCIO-469 Suppresses TNF Generation and Promotes CD34+ Cell Survival in an In Vitro MDS Cell Culture Model
Navas, Tony A., Nguyen, Aaron N., Ma, Jing Y., Stebbins, Elizabeth G., Haghnazari, Edwin, Heaton, Ruth, List, Alan F., Higgins, Linda S.
Published in Blood (16.11.2004)
Published in Blood (16.11.2004)
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Journal Article
SCIO-469, a Potent and Selective Inhibitor of p38a MAPK, Normalizes the Bone Marrow Microenvironment and Inhibits Multiple Myeloma Cell Proliferation in In Vitro and In Vivo Models
Nguyen, Aaron N., Reddy, Mamatha, Henson, Margaret, Stebbins, Elizabeth G., O'Young, Gilbert, Ma, Jing Y., Haghnazari, Edwin, Kapoun, Ann M., Medicherla, Satya, Protter, Andy, Navas, Tony A., Higgins, Linda S.
Published in Blood (16.11.2004)
Published in Blood (16.11.2004)
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Journal Article