HERVs characterize normal and leukemia stem cells and represent a source of shared epitopes for cancer immunotherapy
Alcazer, Vincent, Bonaventura, Paola, Tonon, Laurie, Michel, Emilie, Mutez, Virginie, Fabres, Clémentine, Chuvin, Nicolas, Boulos, Rasha, Estornes, Yann, Maguer‐Satta, Véronique, Geistlich, Kevin, Viari, Alain, Metzeler, Klaus H., Hiddemann, Wolfgang, Batch, Aarif M. N., Herold, Tobias, Caux, Christophe, Depil, Stéphane
Published in American journal of hematology (01.09.2022)
Published in American journal of hematology (01.09.2022)
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Comparative roadmaps of reprogramming and oncogenic transformation identify Bcl11b and Atoh8 as broad regulators of cellular plasticity
Huyghe, A., Furlan, G., Schroeder, J., Cascales, E., Trajkova, A., Ruel, M., Stüder, F., Larcombe, M., Yang Sun, Y. Bo, Mugnier, F., De Matteo, L., Baygin, A., Wang, J., Yu, Y., Rama, N., Gibert, B., Kielbassa, J., Tonon, L., Wajda, P., Gadot, N., Brevet, M., Siouda, M., Mulligan, P., Dante, R., Liu, P., Gronemeyer, H., Mendoza-Parra, M., Polo, J. M., Lavial, F.
Published in Nature cell biology (01.09.2022)
Published in Nature cell biology (01.09.2022)
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Mutational Profile of Aggressive, Localised Prostate Cancer from African Caribbean Men Versus European Ancestry Men
Tonon, Laurie, Fromont, Gaëlle, Boyault, Sandrine, Thomas, Emilie, Ferrari, Anthony, Sertier, Anne-Sophie, Kielbassa, Janice, Le Texier, Vincent, Kamoun, Aurélie, Elarouci, Nabila, Irani, Jacques, Multigner, Luc, Gut, Ivo Glynne, Gut, Marta, Blanchet, Pascal, De Reynies, Aurélien, Cancel-Tassin, Géraldine, Viari, Alain, Cussenot, Olivier
Published in European urology (01.01.2019)
Published in European urology (01.01.2019)
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Epithelial-to-mesenchymal transition promotes immune escape by inducing CD70 in non-small cell lung cancer
Ortiz-Cuaran, Sandra, Swalduz, Aurélie, Foy, Jean-Philippe, Marteau, Solène, Morel, Anne-Pierre, Fauvet, Frédérique, De Souza, Geneviève, Michon, Lucas, Boussageon, Maxime, Gadot, Nicolas, Godefroy, Marion, Léon, Sophie, Tortereau, Antonin, Mourksi, Nour-El-Houda, Leonce, Camille, Albaret, Marie Alexandra, Dongre, Anushka, Vanbervliet, Béatrice, Robert, Marie, Tonon, Laurie, Pommier, Roxane M., Hofman, Véronique, Attignon, Valéry, Boyault, Sandrine, Audoynaud, Carole, Auclair, Jessie, Bouquet, Fanny, Wang, Qing, Ménétrier-Caux, Christine, Pérol, Maurice, Caux, Christophe, Hofman, Paul, Lantuejoul, Sylvie, Puisieux, Alain, Saintigny, Pierre
Published in European journal of cancer (1990) (01.07.2022)
Published in European journal of cancer (1990) (01.07.2022)
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Feasibility of an explainable AI-based therapeutic recommendation-tool utilizing tumor gene expression profiles in advanced and refractory solid tumors
Al Jarroudi, Ouissam, Williams, Coralie, Santos, Rita, Dufresne, Armelle, Attignon, Valéry, Ferrari, Anthony, Boyault, Sandrine, Tonon, Laurie, Tabone-Eglinger, Séverine, Cassier, Philippe Alexandre, Corradini, Nadège, Vinceneux, Armelle, Swalduz, Aurélie, Viari, Alain, Chabaud, Sylvie, Pérol, David, Afshar, Mohammad, Blay, Jean-Yves, Tredan, Olivier, Saintigny, Pierre
Published in Journal of clinical oncology (01.06.2022)
Published in Journal of clinical oncology (01.06.2022)
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Isocitrate dehydrogenase wt and IDHmut adult-type diffuse gliomas display distinct alterations in ribosome biogenesis and 2’O-methylation of ribosomal RNA
Paraqindes, Hermes, Mourksi, Nour-El-Houda, Ballesta, Samantha, Hedjam, Jordan, Bourdelais, Fleur, Fenouil, Tanguy, Picart, Thiébaud, Catez, Frédéric, Combe, Théo, Ferrari, Anthony, Kielbassa, Janice, Thomas, Emilie, Tonon, Laurie, Viari, Alain, Attignon, Valéry, Carrere, Marjorie, Perrossier, Jessie, Giraud, Stéphane, Vanbelle, Christophe, Gabut, Mathieu, Bergeron, Danny, Scott, Michelle S, Castro Vega, Luis, Magne, Nathalie, Huillard, Emmanuelle, Sanson, Marc, Meyronet, David, Diaz, Jean-Jacques, Ducray, François, Marcel, Virginie, Durand, Sébastien
Published in Neuro-oncology (Charlottesville, Va.) (08.12.2023)
Published in Neuro-oncology (Charlottesville, Va.) (08.12.2023)
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항암 백신을 위한 공유된 종양 항원으로서 HERV-K-유래된 항원
CAUX CHRISTOPHE, TONON LAURIE, VALLADEAU JENNY, DEPIL STEPHANE, BONAVENTURA PAOLA
Year of Publication 17.05.2021
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Year of Publication 17.05.2021
Patent
Comprehensive Immune Profiling Unveils a Subset of Leiomyosarcoma with "Hot" Tumor Immune Microenvironment
Feng, Xiaolan, Tonon, Laurie, Li, Haocheng, Darbo, Elodie, Pleasance, Erin, Macagno, Nicolas, Dufresne, Armelle, Brahmi, Mehdi, Bollard, Julien, Ducimetière, Francoise, Karanian, Marie, Meurgey, Alexandra, Pérot, Gaëlle, Valentin, Thibaud, Chibon, Frédéric, Blay, Jean-Yves
Published in Cancers (21.07.2023)
Published in Cancers (21.07.2023)
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Ribosomal RNA 2'O-methylation as a novel layer of inter-tumour heterogeneity in breast cancer
Marcel, Virginie, Kielbassa, Janice, Marchand, Virginie, Natchiar, Kundhavai S, Paraqindes, Hermes, Nguyen Van Long, Flora, Ayadi, Lilia, Bourguignon-Igel, Valérie, Lo Monaco, Piero, Monchiet, Déborah, Scott, Véronique, Tonon, Laurie, Bray, Susan E, Diot, Alexandra, Jordan, Lee B, Thompson, Alastair M, Bourdon, Jean-Christophe, Dubois, Thierry, André, Fabrice, Catez, Frédéric, Puisieux, Alain, Motorin, Yuri, Klaholz, Bruno P, Viari, Alain, Diaz, Jean-Jacques
Published in NAR cancer (01.12.2020)
Published in NAR cancer (01.12.2020)
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Abstract 4530: Single-cell analysis of oral squamous cell carcinoma (OSCC) from smoker vs. non-smoker patients highlights two groups of tumors with distinct immune microenvironments
Meitour, Yannick Le, Vanbervliet, Béatrice, Canjura-Rodriguez, Sonia, Degletagne, Cyril, Tonon, Laurie, Michon, Lucas, Bouaoud, Jebrane, Zrounba, Philippe, Excoffier, Aude, Mahtouk, Karène, Saintigny, Pierre
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Abstract 913: Automated reasoning artificial intelligence (AI) to model the cell-cell biochemical and cellular interactions in the tumor microenvironment (TME) of oral cancer (OC)
Mahtouk, Karène, Vincent, Maxime, Le Meitour, Yannick, Vanbervliet-Defrance, Béatrice, Canjura, Sonia, Degletagne, Cyril, Tonon, Laurie, Michon, Lucas, Bouaoud, Jebrane, Excoffier, Aude, Zrounba, Philippe, Boutonnet, Rémy, Amara, Adam, Saintigny, Pierre
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Ribosomal RNA 2′O-methylation as a novel layer of inter-tumour heterogeneity in breast cancer
Marcel, Virginie, Kielbassa, Janice, Marchand, Virginie, Natchiar, Kundhavai S, Paraqindes, Hermes, Nguyen Van Long, Flora, Ayadi, Lilia, Bourguignon-Igel, Valérie, Lo Monaco, Piero, Monchiet, Déborah, Scott, Véronique, Tonon, Laurie, Bray, Susan E, Diot, Alexandra, Jordan, Lee B, Thompson, Alastair M, Bourdon, Jean-Christophe, Dubois, Thierry, André, Fabrice, Catez, Frédéric, Puisieux, Alain, Motorin, Yuri, Klaholz, Bruno P, Viari, Alain, Diaz, Jean-Jacques
Published in NAR cancer (21.12.2020)
Published in NAR cancer (21.12.2020)
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Cooperative pro-tumorigenic adaptation to oncogenic RAS through epithelial-to-mesenchymal plasticity
De Blander, Hadrien, Tonon, Laurie, Fauvet, Frédérique, Pommier, Roxane M, Lamblot, Christelle, Benhassoun, Rahma, Angileri, Francesca, Gibert, Benjamin, Rodriguez, Raphaël, Ouzounova, Maria, Morel, Anne-Pierre, Puisieux, Alain
Published in Science advances (16.02.2024)
Published in Science advances (16.02.2024)
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Hepatocellular carcinoma hosts cholinergic neural cells and tumoral hepatocytes harboring targetable muscarinic receptors
Hernandez, Charlotte A., Verzeroli, Claire, Roca Suarez, Armando Andres, Farca-Luna, Abud-José, Tonon, Laurie, Esteban, Roger, Pinyol, Roser, Plissonnier, Marie-Laure, Chicherova, Ievgeniia, Dubois, Anaëlle, Bellaud, Pascale, Seffals, Marine, Turlin, Bruno, Fautrel, Alain, Ichim, Gabriel, Rivoire, Michel, Passot, Guillaume, Macek-Jilkova, Zuzana, Decaens, Thomas, Viari, Alain, Testoni, Barbara, Rebouissou, Sandra, Llovet, Josep M., Zoulim, Fabien, Parent, Romain
Published in JHEP reports (01.11.2024)
Published in JHEP reports (01.11.2024)
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Journal Article
BCL2 mutations do not confer adverse prognosis in follicular lymphoma patients treated with rituximab
Huet, Sarah, Szafer‐Glusman, Edith, Tesson, Bruno, Xerri, Luc, Fairbrother, Wayne J., Mukhyala, Kiran, Bolen, Chris, Punnoose, Elizabeth, Tonon, Laurie, Chassagne‐Clément, Catherine, Feugier, Pierre, Viari, Alain, Jardin, Fabrice, Salles, Gilles, Sujobert, Pierre
Published in American journal of hematology (01.06.2017)
Published in American journal of hematology (01.06.2017)
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Exploring the Complementarity of Pancreatic Ductal Adenocarcinoma Preclinical Models
Hoare, Owen, Fraunhoffer, Nicolas, Elkaoutari, Abdessamad, Gayet, Odile, Bigonnet, Martin, Roques, Julie, Nicolle, Rémy, McGuckin, Colin, Forraz, Nico, Sohier, Emilie, Tonon, Laurie, Wajda, Pauline, Boyault, Sandrine, Attignon, Valéry, Tabone-Eglinger, Séverine, Barbier, Sandrine, Mignard, Caroline, Duchamp, Olivier, Iovanna, Juan, Dusetti, Nelson J.
Published in Cancers (19.05.2021)
Published in Cancers (19.05.2021)
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Journal Article
EZH2 alterations in follicular lymphoma: biological and clinical correlations
Huet, S, Xerri, L, Tesson, B, Mareschal, S, Taix, S, Mescam-Mancini, L, Sohier, E, Carrère, M, Lazarovici, J, Casasnovas, O, Tonon, L, Boyault, S, Hayette, S, Haioun, C, Fabiani, B, Viari, A, Jardin, F, Salles, G
Published in Blood cancer journal (New York) (21.04.2017)
Published in Blood cancer journal (New York) (21.04.2017)
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Immune and Genetic Signatures of Breast Carcinomas Triggering Anti-Yo–Associated Paraneoplastic Cerebellar Degeneration
Peter, Elise, Treilleux, Isabelle, Wucher, Valentin, Jougla, Emma, Vogrig, Alberto, Pissaloux, Daniel, Paindavoine, Sandrine, Berthet, Justine, Picard, Géraldine, Rogemond, Véronique, Villard, Marine, Vincent, Clémentine, Tonon, Laurie, Viari, Alain, Honnorat, Jérôme, Dubois, Bertrand, Desestret, Virginie
Published in Neurology : neuroimmunology & neuroinflammation (01.09.2022)
Published in Neurology : neuroimmunology & neuroinflammation (01.09.2022)
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Journal Article
Abstract 6071: Whole-exome RNA sequencing of metastatic synovial sarcomas reveals heterogeneous transcriptomic profile and targetable co-alterations: Cohort study from the French Sarcoma Group
Vanacker, Helene, Brahmi, Mehdi, Meitour, Yannick Le, Bollard, Julien, Attignon, Valery, Meurgey, Alexandra, Jean-Denis, Myriam, Tonon, Laurie, Pokras, Shibani, Klohe, Erika, Nathenson, Michael, Blouch, Kristin, Eleftheriadou, Ioanna, Blay, Jean-Yves, Tirode, Franck, Dufresne, Armelle
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Abstract 1221: Selective translational activation of PBK (PDZ- binding kinase) reveals a molecular vulnerability of drug-tolerant persister cells to targeted therapies in EGFR -mutant lung adenocarcinoma
Leonce, Camille, Désage, Anne-Laure, Mourksi, Nour El-Houda, De Souza, Geneviève, Vanbervliet, Béatrice, Charrondière, Camille, Nicq, Constance, Néri, Jérémy, Swalduz, Aurélie, Tonon, Laurie, Cumunel, Eric, Gadot, Nicolas, Ichim, Gabriel, Diaz, Jean-Jacques, Lovly, Christine, Mazières, Julien, Tabutin, Mayeul, Pérol, Maurice, Lantuejoul, Sylvie, Calvayrac, Olivier, Forest, Fabien, Marcel, Virginie, Saintigny, Pierre, Ortiz-Cuaran, Sandra
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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