The interactions of lenalidomide with human uptake and efflux transporters and UDP-glucuronosyltransferase 1A1: lack of potential for drug–drug interactions
Tong, Zeen, Yerramilli, Usha, Surapaneni, Sekhar, Kumar, Gondi
Published in Cancer chemotherapy and pharmacology (01.04.2014)
Published in Cancer chemotherapy and pharmacology (01.04.2014)
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Journal Article
Metabolism of Vabicaserin in Mice, Rats, Dogs, Monkeys, and Humans
ZEEN TONG, CHANDRASEKARAN, Appavu, DEMAIO, William, ESPINA, Robert, WEI LU, JORDAN, Ronald, SCATINA, Joann
Published in Drug metabolism and disposition (01.12.2010)
Published in Drug metabolism and disposition (01.12.2010)
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Journal Article
"Cocktail" approaches and strategies in drug development: valuable tool or flawed science?
Zhou, Honghui, Tong, Zeen, McLeod, James F
Published in Journal of clinical pharmacology (01.02.2004)
Published in Journal of clinical pharmacology (01.02.2004)
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Journal Article
Assessment of Transporter-Mediated Drug Interactions for Enasidenib Based on a Cocktail Study in Patients With Relapse or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome
Cheng, Yiming, Wang, Xiaomin, Tong, Zeen, Reyes, Josephine, Carayannopoulos, Leon, Zhou, Simon, Li, Yan
Published in Journal of clinical pharmacology (01.04.2022)
Published in Journal of clinical pharmacology (01.04.2022)
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Journal Article
Dietary Modulation of Phase 1 and Phase 2 Activities with Benzo(a)pyrene and Related Compounds in the Intestine But Not the Liver of the Channel Catfish, Ictalurus punctatus
JAMES, M. O, ALTMAN, A. H, MORRIS, K, KLEINOW, K. M, TONG, Z
Published in Drug metabolism and disposition (01.03.1997)
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Published in Drug metabolism and disposition (01.03.1997)
Journal Article
Intestinal Bioavailability and Biotransformation of 3-Hydroxybenzo(a)pyrene in an Isolated Perfused Preparation from Channel Catfish, Ictalurus punctatus
James, M O, Tong, Z, Rowland-Faux, L, Venugopal, C S, Kleinow, K M
Published in Drug metabolism and disposition (01.05.2001)
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Published in Drug metabolism and disposition (01.05.2001)
Journal Article
Assessment of drug-drug interactions of CC-90001, a potent and selective inhibitor of c-Jun N-terminal kinase
Tong, Zeen, Gaudy, Allison, Tatosian, Daniel, Ramirez-Valle, Francisco, Liu, Hong, Chen, Jian, Hoffmann, Matthew, Surapaneni, Sekhar
Published in Xenobiotica (02.12.2021)
Published in Xenobiotica (02.12.2021)
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Journal Article
Nuclear Magnetic Resonance Spectroscopy as a Quantitative Tool To Determine the Concentrations of Biologically Produced Metabolites: Implications in Metabolites in Safety Testing
Espina, Robert, Yu, Linning, Wang, Jianyao, Tong, Zeen, Vashishtha, Sarvesh, Talaat, Rasmy, Scatina, JoAnn, Mutlib, Abdul
Published in Chemical research in toxicology (01.02.2009)
Published in Chemical research in toxicology (01.02.2009)
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Journal Article
Assessment of interaction with nucleosidal transporters between enasidenib and azacytidine
Yerramilli, Usha, Hoffmann, Matthew, Surapaneni, Sekhar, Tong, Zeen
Published in Drug metabolism and pharmacokinetics (01.01.2019)
Published in Drug metabolism and pharmacokinetics (01.01.2019)
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Journal Article
Superior therapeutic efficacy of nab-paclitaxel over cremophor-based paclitaxel in locally advanced and metastatic models of human pancreatic cancer
Rajeshkumar, N V, Yabuuchi, Shinichi, Pai, Shweta G, Tong, Zeen, Hou, Shihe, Bateman, Scott, Pierce, Daniel W, Heise, Carla, Von Hoff, Daniel D, Maitra, Anirban, Hidalgo, Manuel
Published in British journal of cancer (09.08.2016)
Published in British journal of cancer (09.08.2016)
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Journal Article
Absorption, distribution, metabolism and excretion of an isocitrate dehydrogenase-2 inhibitor enasidenib in rats and humans
Tong, Zeen, Atsriku, Christian, Yerramilli, Usha, Wang, Xiaomin, Li, Yan, Reyes, Josephine, Fan, Bin, Yang, Hua, Hoffmann, Matthew, Surapaneni, Sekhar
Published in Xenobiotica (01.02.2019)
Published in Xenobiotica (01.02.2019)
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Journal Article
In vitro inhibition of human nucleoside transporters and uptake of azacitidine by an isocitrate dehydrogenase-2 inhibitor enasidenib and its metabolite AGI-16903
Tong, Zeen, Yerramilli, Usha, Yao, Sylvia, Young, James D., Hoffmann, Matthew, Surapaneni, Sekhar
Published in Xenobiotica (03.10.2019)
Published in Xenobiotica (03.10.2019)
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Journal Article
Assessment of drug-drug interaction potential and PBPK modeling of CC-223, a potent inhibitor of the mammalian target of rapamycin kinase
Tong, Zeen, Narayanan, Rangaraj, Atsriku, Christian, Nissel, Jim, Li, Yan, Liu, Hong, Wang, Xiaomin, Surapaneni, Sekhar
Published in Xenobiotica (02.01.2019)
Published in Xenobiotica (02.01.2019)
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Journal Article