Search Results - "TONG Youzhi" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Activity of preclinical and phase I clinical trial of a novel androgen receptor antagonist GT0918 in metastatic breast cancer

Activity of preclinical and phase I clinical trial of a novel androgen receptor antagonist GT0918 in metastatic breast cancer

by Li, Huiping, Song, Guohong, Zhou, Qiaoxia, Ran, Ran, Jiang, Hanfang, Zhang, Ruyan, Liu, Yaxin, Zhang, Jiayang, Meng, Luping, Ma, Liandong, Sun, Ye, Wang, Meiyu, Zhou, Qingqing, Yan, Honghua, Zhou, Qianxiang, Dong, Xunwei, Tong, Youzhi
Published in Breast cancer research and treatment (01.10.2021)

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Journal Article

$Macro-micro dynamic behaviors and fracture modes of roll bonded 7A52/7A01/7B52 aluminum laminates in high velocity deformation$

Macro-micro dynamic behaviors and fracture modes of roll bonded 7A52/7A01/7B52 aluminum laminates in high velocity deformation

by Zhu, Guochuan, Huang, Shuhui, Li, Xiwu, Li, Zhihui, Tong, Youzhi, Zhang, Yongan, Xiong, Baiqing
Published in Progress in natural science (01.08.2018)

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Journal Article

Prediction of residual stress field on the surface of quenched 7055 aluminium alloy plates

Prediction of residual stress field on the surface of quenched 7055 aluminium alloy plates

by Ren, Weicai, Li, Yanan, Zhang, Yongan, Tong, Youzhi, Li, Xiwu, Li, Zhihui, Xiong, Baiqing
Published in Materials research express (01.03.2022)

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Journal Article

Combined intratumoral injection of bone marrow-derived dendritic cells and systemic chemotherapy to treat pre-existing murine tumors

Combined intratumoral injection of bone marrow-derived dendritic cells and systemic chemotherapy to treat pre-existing murine tumors

by YOUZHI TONG, WENRU SONG, CRYSTAL, Ronald G
Published in Cancer research (Chicago, Ill.) (15.10.2001)

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Journal Article

Structural determinants of the BRCA1 : estrogen receptor interaction

Structural determinants of the BRCA1 : estrogen receptor interaction

by YONG XIAN MA, TOMITA, York, SAIJUN FAN, KONGMING WU, YOUZHI TONG, ZEGUO ZHAO, SONG, Liang-Nian, GOLDBERG, Itzhak D, ROSEN, Eliot M
Published in Oncogene (10.03.2005)

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Journal Article

Biomarker analysis (CTC and ctDNA/RNA) of GT0918 (Proxalutamide) new AR blocker in phase I mCRPC patients with dose escalation

Biomarker analysis (CTC and ctDNA/RNA) of GT0918 (Proxalutamide) new AR blocker in phase I mCRPC patients with dose escalation

by Zhou, Karl, Zhang, Phoebe, Tong, Youzhi, Ma, Liandong
Published in Journal of clinical oncology (20.02.2020)

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Journal Article

Treatment with GT1708F, an Oral Smoothened Inhibitor, in Patients with Myeloid Malignancies: A Phase I Study

Treatment with GT1708F, an Oral Smoothened Inhibitor, in Patients with Myeloid Malignancies: A Phase I Study

by Jin, Jie, Qi, Junyuan, Zhao, Weihua, Wang, Huafeng, Song, Lin, Lin, Yu, Tong, Youzhi, Ni, Xiang, Dong, Min, He, Xiaohan
Published in Blood (02.11.2023)

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Journal Article

Abstract 711: Repurposing 2nd generation androgen receptor antagonist Proxalutamide to treat COVID-19

Abstract 711: Repurposing 2nd generation androgen receptor antagonist Proxalutamide to treat COVID-19

by Ma, Liandong, Tong, Youzhi, Guo, Qiang, Zhou, Yifeng, Zhou, Qianxiang, Yan, Honghua
Published in Cancer research (Chicago, Ill.) (01.07.2021)

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Journal Article

Targeted Protein Degradation for c-MYC Overcomes Therapy Resistance in T-Cell Acute Lymphoblastic Leukemias

Targeted Protein Degradation for c-MYC Overcomes Therapy Resistance in T-Cell Acute Lymphoblastic Leukemias

by Munir, Faryal, Khazaei, Shayaun, Calkins, Phoebe H., Scruggs, Darah, Mizuno, Hideaki, Ostermann, Lauren B., Cuglievan, Branko, Garcia, Miriam B., Chen, Dong, Tong, Youzhi, Ren, Zhihua, Andreeff, Michael, Nishida, Yuki
Published in Blood (02.11.2023)

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Journal Article

Fe-rich particles influenced secondary crack characteristics in an Al-Zn-Mg-Cu alloy extrusion plate with high zinc content

Fe-rich particles influenced secondary crack characteristics in an Al-Zn-Mg-Cu alloy extrusion plate with high zinc content

by Wen, Kai, Xiong, Baiqing, Ren, Weicai, Tong, Youzhi, Li, Xiwu, Li, Zhihui, Zhang, Yongan, Li, Yanan, Yan, Lizhen, Yan, Hongwei, Liu, Hongwei
Published in Scripta materialia (01.09.2020)

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Journal Article

라파마이신 신호전달 경로 저해제의 기계적 표적 및 이의 치료학적 적용

라파마이신 신호전달 경로 저해제의 기계적 표적 및 이의 치료학적 적용

by GUO CHUANGXING, TONG YOUZHI
Year of Publication 27.02.2019

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Patent

Microenvironmental pH-modified solid dispersions to enhance the dissolution and bioavailability of poorly water-soluble weakly basic GT0918, a developing anti-prostate cancer drug: Preparation, characterization and evaluation in vivo

Microenvironmental pH-modified solid dispersions to enhance the dissolution and bioavailability of poorly water-soluble weakly basic GT0918, a developing anti-prostate cancer drug: Preparation, characterization and evaluation in vivo

by Yang, Meiyan, He, Shaolong, Fan, Yunzhou, Wang, Yuli, Ge, Zhenzhong, Shan, Li, Gong, Wei, Huang, Xiaoli, Tong, Youzhi, Gao, Chunsheng
Published in International journal of pharmaceutics (20.11.2014)

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Journal Article

Proxalutamide in patients with AR-positive metastatic breast cancer: Results from an open-label multicentre phase Ib study and biomarker analysis

Proxalutamide in patients with AR-positive metastatic breast cancer: Results from an open-label multicentre phase Ib study and biomarker analysis

by Jiang, Hanfang, Ouyang, Quchang, Yin, Yongmei, Tong, Zhongshen, Shen, Kunwei, Yuan, Zhongyu, Geng, Cuizhi, Liu, Yaxin, Song, Guohong, Ran, Ran, Li, Wei, Qu, Qing, Wang, Meiyu, Meng, Luping, Tong, Youzhi, Li, Huiping
Published in European journal of cancer (1990) (01.11.2022)

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Journal Article

Abstract 1265: Discovery of GT19077, a c-Myc/Max protein-protein Interaction (PPI) small molecule inhibitor, and GT19506 a c-Myc PROTAC molecule, for targeting c-Myc-driven blood cancers and small cell lung cancers

Abstract 1265: Discovery of GT19077, a c-Myc/Max protein-protein Interaction (PPI) small molecule inhibitor, and GT19506 a c-Myc PROTAC molecule, for targeting c-Myc-driven blood cancers and small cell lung cancers

by Ma, Liandong, Tong, Youzhi, Zhou, Qianxiang, Yang, Zhaohui, Yan, Honghau, Chen, Ye, Xu, Ruo, Pan, Jie, Gou, Xiaoqi, Qian, Weidong, Chen, Jie, Sun, Qi, Lai, Luhua
Published in Cancer research (Chicago, Ill.) (01.07.2021)

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Journal Article

High‐resolution structures of inhibitor complexes of human indoleamine 2,3‐dioxygenase 1 in a new crystal form

High‐resolution structures of inhibitor complexes of human indoleamine 2,3‐dioxygenase 1 in a new crystal form

by Luo, Shukun, Xu, Ke, Xiang, Shaoyun, Chen, Jie, Chen, Chunyun, Guo, Chuangxin, Tong, Youzhi, Tong, Liang
Published in Acta crystallographica. Section F, Structural biology communications (01.11.2018)

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Journal Article

Safety and efficacy of combination of GT90001, an anti-activin receptor-like kinase-1 (ALK-1) antibody, and nivolumab in patients with metastatic hepatocellular carcinoma (HCC)

Safety and efficacy of combination of GT90001, an anti-activin receptor-like kinase-1 (ALK-1) antibody, and nivolumab in patients with metastatic hepatocellular carcinoma (HCC)

by Hsu, Chiun, Chang, Yi-Fang, Yen, Chia-Jui, Lu, Li-Chun, Zhu, Xiaoyan, Xu, Yuwei, Zhou, Qiaoxia, Dong, Xunwei, Tong, Youzhi
Published in Journal of clinical oncology (20.01.2021)

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Journal Article

Abstract 6509: GT0486, a novel mTORC1/2 dual inhibitor, exhibits synergistic antitumor efficacy in combination with BTK inhibitors

Abstract 6509: GT0486, a novel mTORC1/2 dual inhibitor, exhibits synergistic antitumor efficacy in combination with BTK inhibitors

by Hou, Xiaodan, Yan, Honghua, Zhang, Xin, Qian, Weidong, Chen, Dong, Ren, Zhihua, Tong, Youzhi
Published in Cancer research (Chicago, Ill.) (22.03.2024)

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Journal Article

Abstract 3297: Discovery and evaluation of GT19870, a GSPT1/Myc molecular glue drug (MGD) with oral bioavailability for targeting c-Myc and n-Myc-addictive blood cancer and solid tumors

Abstract 3297: Discovery and evaluation of GT19870, a GSPT1/Myc molecular glue drug (MGD) with oral bioavailability for targeting c-Myc and n-Myc-addictive blood cancer and solid tumors

by Ma, Liandong, Tong, Youzhi, Yang, Zhaohui, Zhou, Qiangxiang, Yan, Honghua, Xu, Ru, Chen, Dong
Published in Cancer research (Chicago, Ill.) (22.03.2024)

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Journal Article

Abstract 2735: High affinity and potent anti-tumor efficacy of Nivo813, an anti-PD-1/ALK-1 bispecific antibody, in pre-clinical studies for solid tumors

Abstract 2735: High affinity and potent anti-tumor efficacy of Nivo813, an anti-PD-1/ALK-1 bispecific antibody, in pre-clinical studies for solid tumors

by Zhou, Qingqing, Tang, Rong, Zhuang, Lanfang, Huang, Jianyu, Qian, Jiang, Ren, Zhihua, Tong, Youzhi
Published in Cancer research (Chicago, Ill.) (22.03.2024)

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Journal Article

Isolation and Characterization of Thymitaq (AG337) and 5-Fluoro-2-deoxyuridylate-resistant Mutants of Human Thymidylate Synthase from Ethyl Methanesulfonate-exposed Human Sarcoma HT1080 Cells

Isolation and Characterization of Thymitaq (AG337) and 5-Fluoro-2-deoxyuridylate-resistant Mutants of Human Thymidylate Synthase from Ethyl Methanesulfonate-exposed Human Sarcoma HT1080 Cells

by Tong, Y, Liu-Chen, X, Ercikan-Abali, E A, Capiaux, G M, Zhao, S C, Banerjee, D, Bertino, J R
Published in The Journal of biological chemistry (08.05.1998)

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