Humanized mouse model of mast cell–mediated passive cutaneous anaphylaxis and passive systemic anaphylaxis
Bryce, Paul J., PhD, Falahati, Rustom, PhD, Kenney, Laurie L., PhD, Leung, John, BS, Bebbington, Christopher, PhD, Tomasevic, Nenad, PhD, Krier, Rebecca A., MS, Hsu, Chia-Lin, PhD, Shultz, Leonard D., PhD, Greiner, Dale L., PhD, Brehm, Michael A., PhD
Published in Journal of allergy and clinical immunology (01.09.2016)
Published in Journal of allergy and clinical immunology (01.09.2016)
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A monoclonal antibody to Siglec-8 suppresses non-allergic airway inflammation and inhibits IgE-independent mast cell activation
Schanin, Julia, Gebremeskel, Simon, Korver, Wouter, Falahati, Rustom, Butuci, Melina, Haw, Tatt Jhong, Nair, Prema M., Liu, Gang, Hansbro, Nicole G., Hansbro, Philip M., Evensen, Erik, Brock, Emily C., Xu, Alan, Wong, Alan, Leung, John, Bebbington, Christopher, Tomasevic, Nenad, Youngblood, Bradford A.
Published in Mucosal immunology (01.03.2021)
Published in Mucosal immunology (01.03.2021)
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Src phosphorylation of cortactin enhances actin assembly
Tehrani, Shandiz, Tomasevic, Nenad, Weed, Scott, Sakowicz, Roman, Cooper, John A
Published in Proceedings of the National Academy of Sciences - PNAS (17.07.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (17.07.2007)
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R-Spondin family members regulate the Wnt pathway by a common mechanism
Kim, Kyung-Ah, Wagle, Marie, Tran, Karolyn, Zhan, Xiaoming, Dixon, Melissa A, Liu, Shouchun, Gros, Delphine, Korver, Wouter, Yonkovich, Shirlee, Tomasevic, Nenad, Binnerts, Minke, Abo, Arie
Published in Molecular biology of the cell (01.06.2008)
Published in Molecular biology of the cell (01.06.2008)
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Discovery, Function, and Therapeutic Targeting of Siglec-8
Youngblood, Bradford A, Leung, John, Falahati, Rustom, Williams, Jason, Schanin, Julia, Brock, Emily C, Singh, Bhupinder, Chang, Alan T, O'Sullivan, Jeremy A, Schleimer, Robert P, Tomasevic, Nenad, Bebbington, Christopher R, Bochner, Bruce S
Published in Cells (Basel, Switzerland) (24.12.2020)
Published in Cells (Basel, Switzerland) (24.12.2020)
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The eosinophil surface receptor epidermal growth factor–like module containing mucin-like hormone receptor 1 (EMR1): A novel therapeutic target for eosinophilic disorders
Legrand, Fanny, PhD, PharmD, Tomasevic, Nenad, PhD, Simakova, Olga, PhD, Lee, Chyi-Chia Richard, MD, PhD, Wang, Zengfang, PhD, Raffeld, Mark, MD, Makiya, Michelle A., MS, Palath, Varghese, PhD, Leung, John, BS, Baer, Mark, PhD, Yarranton, Geoffrey, PhD, Maric, Irina, MD, Bebbington, Christopher, PhD, Klion, Amy D., MD
Published in Journal of allergy and clinical immunology (01.05.2014)
Published in Journal of allergy and clinical immunology (01.05.2014)
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R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6
Binnerts, Minke E, Kim, Kyung-Ah, Bright, Jessica M, Patel, Sejal M, Tran, Karolyn, Zhou, Mei, Leung, John M, Liu, Yi, Lomas, Woodrow E. III, Dixon, Melissa, Hazell, Sophie A, Wagle, Marie, Nie, Wen-Sheng, Tomasevic, Nenad, Williams, Jason, Zhan, Xiaoming, Levy, Michael D, Funk, Walter D, Abo, Arie
Published in Proceedings of the National Academy of Sciences - PNAS (11.09.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (11.09.2007)
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FAK promotes organization of fibronectin matrix and fibrillar adhesions
Ilić, Dusko, Kovacic, Branka, Johkura, Kohei, Schlaepfer, David D, Tomasević, Nenad, Han, Qin, Kim, Jae-Beom, Howerton, Kyle, Baumbusch, Clark, Ogiwara, Naoko, Streblow, Daniel N, Nelson, Jay A, Dazin, Paul, Shino, Yuji, Sasaki, Katsunori, Damsky, Caroline H
Published in Journal of cell science (15.01.2004)
Published in Journal of cell science (15.01.2004)
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Differential Regulation of WASP and N-WASP by Cdc42, Rac1, Nck, and PI(4,5)P2
Tomasevic, Nenad, Jia, Zhiheng, Russell, Alan, Fujii, Toby, Hartman, James J, Clancy, Sheila, Wang, Manping, Beraud, Christophe, Wood, Kenneth W, Sakowicz, Roman
Published in Biochemistry (Easton) (20.03.2007)
Published in Biochemistry (Easton) (20.03.2007)
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Siglec-8 antibody reduces eosinophils and mast cells in a transgenic mouse model of eosinophilic gastroenteritis
Youngblood, Bradford A., Brock, Emily C., Leung, John, Falahati, Rustom, Bochner, Bruce S., Rasmussen, Henrik S., Peterson, Kathryn, Bebbington, Christopher, Tomasevic, Nenad
Published in JCI insight (03.10.2019)
Published in JCI insight (03.10.2019)
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Human EMR1, An Eosinophil-Specific Surface Receptor Of Unknown Function, Is Modulated In Vivo and In Vitro
Legrand, Fanny, Dr, Tomasevic, Nenad, Dr, Makiya, Michelle, Mrs, Bebbington, Christopher, Dr, Klion, Amy D., Dr
Published in Journal of allergy and clinical immunology (01.02.2014)
Published in Journal of allergy and clinical immunology (01.02.2014)
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Novel Anti-Siglec-8 Antibody Reduces Eosinophil and Mast Cell Infiltration in a Mouse Model of Eosinophilic Gastroenteritis: 1176
Youngblood, Bradford, Brock, Emily, Leung, John, Bebbington, Christopher, Tomasevic, Nenad
Published in The American journal of gastroenterology (01.10.2018)
Published in The American journal of gastroenterology (01.10.2018)
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AK002, a Humanized Sialic Acid-Binding Immunoglobulin-Like Lectin-8 Antibody that Induces Antibody-Dependent Cell-Mediated Cytotoxicity against Human Eosinophils and Inhibits Mast Cell-Mediated Anaphylaxis in Mice
Youngblood, Bradford A., Brock, Emily C., Leung, John, Falahati, Rustom, Bryce, Paul J., Bright, Jessica, Williams, Jason, Shultz, Leonard D., Greiner, Dale L., Brehm, Michael A., Bebbington, Christopher, Tomasevic, Nenad
Published in International archives of allergy and immunology (01.09.2019)
Published in International archives of allergy and immunology (01.09.2019)
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Sialic acid–binding immunoglobulin-like lectin (Siglec) 8 in patients with eosinophilic disorders: Receptor expression and targeting using chimeric antibodies
Legrand, Fanny, Cao, Yun, Wechsler, Joshua B., Zhu, Xiang, Zimmermann, Nives, Rampertaap, Shakuntala, Monsale, Joseph, Romito, Kimberly, Youngblood, Bradford A., Brock, Emily C., Makiya, Michelle A., Tomasevic, Nenad, Bebbington, Christopher, Maric, Irina, Metcalfe, Dean D., Bochner, Bruce S., Klion, Amy D.
Published in Journal of allergy and clinical immunology (01.06.2019)
Published in Journal of allergy and clinical immunology (01.06.2019)
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Journal Article
Siglec-8 antibody reduces eosinophils and mast cells in a transgenic mouse model of eosinophilic gastroenteritis
Youngblood, Bradford A., Brock, Emily C., Leung, John, Falahati, Rustom, Bochner, Bruce S., Rasmussen, Henrik S., Peterson, Kathryn, Bebbington, Christopher, Tomasevic, Nenad
Published in JCI insight (03.10.2019)
Published in JCI insight (03.10.2019)
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