Short-Chain Fatty Acids Stimulate Glucagon-Like Peptide-1 Secretion via the G-Protein―Coupled Receptor FFAR2
TOLHURST, Gwen, HEFFRON, Helen, LAM, Yu Shan, PARKER, Helen E, HABIB, Abdella M, DIAKOGIANNAKI, Eleftheria, CAMERON, Jennifer, GROSSE, Johannes, REIMANN, Frank, GRIBBLE, Fiona M
Published in Diabetes (New York, N.Y.) (01.02.2012)
Published in Diabetes (New York, N.Y.) (01.02.2012)
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Journal Article
Nutritional regulation of glucagon-like peptide-1 secretion
Tolhurst, Gwen, Reimann, Frank, Gribble, Fiona M.
Published in The Journal of physiology (01.01.2009)
Published in The Journal of physiology (01.01.2009)
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Journal Article
Adenosine triphosphate is co-secreted with glucagon-like peptide-1 to modulate intestinal enterocytes and afferent neurons
Lu, Van B., Rievaj, Juraj, O’Flaherty, Elisabeth A., Smith, Christopher A., Pais, Ramona, Pattison, Luke A., Tolhurst, Gwen, Leiter, Andrew B., Bulmer, David C., Gribble, Fiona M., Reimann, Frank
Published in Nature communications (04.03.2019)
Published in Nature communications (04.03.2019)
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Journal Article
Mechanistic insights into the detection of free fatty and bile acids by ileal glucagon-like peptide-1 secreting cells
Goldspink, Deborah A, Lu, Van B, Billing, Lawrence J, Larraufie, Pierre, Tolhurst, Gwen, Gribble, Fiona M, Reimann, Frank
Published in Molecular metabolism (Germany) (01.01.2018)
Published in Molecular metabolism (Germany) (01.01.2018)
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Journal Article
Molecular and electrophysiological characterization of transient receptor potential ion channels in the primary murine megakaryocyte
Carter, Richard N, Tolhurst, Gwen, Walmsley, Gemma, Vizuete-Forster, Matthieu, Miller, Nigel, Mahaut-Smith, Martyn P
Published in The Journal of physiology (01.10.2006)
Published in The Journal of physiology (01.10.2006)
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Journal Article
Expression profiling and electrophysiological studies suggest a major role for Orai1 in the store-operated Ca2+ influx pathway of platelets and megakaryocytes
Tolhurst, Gwen, Carter, Richard N., Amisten, Stefan, Holdich, Jon P., Erlinge, David, Mahaut-Smith, Martyn P.
Published in Platelets (Edinburgh) (01.01.2008)
Published in Platelets (Edinburgh) (01.01.2008)
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Journal Article
Oligopeptides stimulate glucagon-like peptide-1 secretion in mice through proton-coupled uptake and the calcium-sensing receptor
Diakogiannaki, Eleftheria, Pais, Ramona, Tolhurst, Gwen, Parker, Helen E., Horscroft, James, Rauscher, Beate, Zietek, Tamara, Daniel, Hannelore, Gribble, Fiona M., Reimann, Frank
Published in Diabetologia (01.12.2013)
Published in Diabetologia (01.12.2013)
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Journal Article
Glucose Sensing in L Cells: A Primary Cell Study
Reimann, Frank, Habib, Abdella M., Tolhurst, Gwen, Parker, Helen E., Rogers, Gareth J., Gribble, Fiona M.
Published in Cell metabolism (06.12.2008)
Published in Cell metabolism (06.12.2008)
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Journal Article
Intestinal sensing of nutrients
Tolhurst, Gwen, Reimann, Frank, Gribble, Fiona M
Published in Handbook of experimental pharmacology (2012)
Published in Handbook of experimental pharmacology (2012)
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Journal Article
Mixed Primary Cultures of Murine Small Intestine Intended for the Study of Gut Hormone Secretion and Live Cell Imaging of Enteroendocrine Cells
Psichas, Arianna, Tolhurst, Gwen, Brighton, Cheryl A, Gribble, Fiona M, Reimann, Frank
Published in Journal of visualized experiments (20.04.2017)
Published in Journal of visualized experiments (20.04.2017)
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Journal Article
Mixed Primary Cultures of Murine Small Intestine Intended for the Study of Gut Hormone Secretion and Live Cell Imaging of Enteroendocrine Cells
Psichas, Arianna, Tolhurst, Gwen, Brighton, Cheryl A., Gribble, Fiona M., Reimann, Frank
Published in Journal of visualized experiments (20.04.2017)
Published in Journal of visualized experiments (20.04.2017)
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Journal Article
Interplay between P2Y1, P2Y12, and P2X1 receptors in the activation of megakaryocyte cation influx currents by ADP: evidence that the primary megakaryocyte represents a fully functional model of platelet P2 receptor signaling
Tolhurst, Gwen, Vial, Catherine, Léon, Catherine, Gachet, Christian, Evans, Richard J., Mahaut-Smith, Martyn P.
Published in Blood (01.09.2005)
Published in Blood (01.09.2005)
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Journal Article
Role of phosphodiesterase and adenylate cyclase isozymes in murine colonic glucagon‐like peptide 1 secreting cells
Friedlander, Ronn S., Moss, Catherine E., Mace, Jessica, Parker, Helen E., Tolhurst, Gwen, Habib, Abdella M., Wachten, Sebastian, Cooper, Dermot M., Gribble, Fiona M., Reimann, Frank
Published in British journal of pharmacology (01.05.2011)
Published in British journal of pharmacology (01.05.2011)
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Journal Article
Hypogonadotropic Hypogonadism due to a Novel Missense Mutation in the First Extracellular Loop of the Neurokinin B Receptor
Guran, Tulay, Tolhurst, Gwen, Bereket, Abdullah, Rocha, Nuno, Porter, Keith, Turan, Serap, Gribble, Fiona M, Kotan, L. Damla, Akcay, Teoman, Atay, Zeynep, Canan, Husniye, Serin, Ayse, O'Rahilly, Stephen, Reimann, Frank, Semple, Robert K, Topaloglu, A. Kemal
Published in The journal of clinical endocrinology and metabolism (01.10.2009)
Published in The journal of clinical endocrinology and metabolism (01.10.2009)
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Journal Article
Interplay between P2Y(1), P2Y(12), and P2X(1) receptors in the activation of megakaryocyte cation influx currents by ADP: evidence that the primary megakaryocyte represents a fully functional model of platelet P2 receptor signaling
Tolhurst, Gwen, Vial, Catherine, Léon, Catherine, Gachet, Christian, Evans, Richard J, Mahaut-Smith, Martyn P
Published in Blood (01.09.2005)
Published in Blood (01.09.2005)
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Journal Article
Emerging roles for P2X1 receptors in platelet activation
Mahaut-Smith, Martyn P., Tolhurst, Gwen, Evans, Richard J.
Published in Platelets (Edinburgh) (01.05.2004)
Published in Platelets (Edinburgh) (01.05.2004)
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Journal Article
Expression profiling and electrophysiological studies suggest a major role for Orai1 in the store-operated Ca 2 + influx pathway of platelets and megakaryocytes
Tolhurst, Gwen, Carter, Richard N., Amisten, Stefan, Holdich, Jon P., Erlinge, David, Mahaut-Smith, Martyn P.
Published in Platelets (Edinburgh) (01.01.2008)
Published in Platelets (Edinburgh) (01.01.2008)
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Journal Article