Association study of genetic polymorphisms of drug transporters, SLCO1B1, SLCO1B3 and ABCC2, in African-Americans, Hispanics and Caucasians and olmesartan exposure
Endo, Seiko, Fukahori, Aiko, Tokuhiro, Shinya, Shinagawa, Akira, Walker, Joseph, Yoshihara, Kazutaka, Ishizuka, Hitoshi, Ieiri, Ichiro, Sugiyama, Yuichi
Published in Journal of human genetics (01.08.2012)
Published in Journal of human genetics (01.08.2012)
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The Presenilin 2 Mutation (N141I) Linked to Familial Alzheimer Disease (Volga German Families) Increases the Secretion of Amyloid β Protein Ending at the 42nd (or 43rd) Residue
Tomita, Taisuke, Maruyama, Kei, Saido, Takaomi C., Kume, Hideaki, Shinozaki, Kohki, Tokuhiro, Shinya, Capell, Anja, Walter, Jochen, Grünberg, Jürgen, Haass, Christian, Iwatsubo, Takeshi, Obata, Kunihiko
Published in Proceedings of the National Academy of Sciences - PNAS (04.03.1997)
Published in Proceedings of the National Academy of Sciences - PNAS (04.03.1997)
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Caspase activation during apoptotic cell death induced by expanded polyglutamine in N2a cells
Wang, G H, Mitsui, K, Kotliarova, S, Yamashita, A, Nagao, Y, Tokuhiro, S, Iwatsubo, T, Kanazawa, I, Nukina, N
Published in Neuroreport (20.08.1999)
Published in Neuroreport (20.08.1999)
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Journal Article
SLC22A4 and RUNX1: identification of RA susceptible genes
YAMADA, Ryo, TOKUHIRO, Shinya, XIOTIAN CHANG, YAMAMOTO, Kazuhiko
Published in Journal of molecular medicine (Berlin, Germany) (01.09.2004)
Published in Journal of molecular medicine (Berlin, Germany) (01.09.2004)
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Journal Article
Functional haplotypes of PADI4 , encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis
Yamada, Ryo, Suzuki, Akari, Chang, Xiaotian, Tokuhiro, Shinya, Sawada, Tetsuji, Suzuki, Masakatsu, Nagasaki, Miyuki, Nakayama-Hamada, Makiko, Kawaida, Reimi, Ono, Mitsuru, Ohtsuki, Masahiko, Furukawa, Hidehiko, Yoshino, Shinichi, Yukioka, Masao, Tohma, Shigeto, Matsubara, Tsukasa, Wakitani, Shigeyuki, Teshima, Ryota, Nishioka, Yuichi, Sekine, Akihiro, Iida, Aritoshi, Takahashi, Atsushi, Tsunoda, Tatsuhiko, Nakamura, Yusuke, Yamamoto, Kazuhiko
Published in Nature genetics (01.08.2003)
Published in Nature genetics (01.08.2003)
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A phase I, open label, two part, safety and tolerability study of U3-1784 in patients with advanced solid tumours
Ciprotti, Marika, Abraham, Reimar, Jansen, Mendel, Tokuhiro, Shinya, Hanai, Masaharu, Oitate, Masataka, Shuster, Dale Edward, Martinez, Alberto
Published in Journal of clinical oncology (20.05.2016)
Published in Journal of clinical oncology (20.05.2016)
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Preclinical efficacy studies of DS-1062a, a novel TROP2-targeting antibody-drug conjugate with a novel DNA topoisomerase I inhibitor DXd
Okajima, Daisuke, Yasuda, Satoru, Yokouchi, Yusuke, Fujitani, Tomomichi, Sakurai, Ken, Yamaguchi, Junko, Kitamura, Michiko, Terauchi, Tomoko, Shibutani, Tomoko, Aida, Tetsuo, Nakada, Takashi, Tokuhiro, Shinya, Toki, Tadashi, Noguchi, Yutaka, Abe, Yuki, Agatsuma, Toshinori
Published in Journal of clinical oncology (20.05.2018)
Published in Journal of clinical oncology (20.05.2018)
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Journal Article
An intronic SNP in a RUNX1 binding site of SLC22A4 , encoding an organic cation transporter, is associated with rheumatoid arthritis
Yamada, Ryo, Tokuhiro, Shinya, Chang, Xiaotian, Suzuki, Akari, Kochi, Yuta, Sawada, Tetsuji, Suzuki, Masakatsu, Nagasaki, Miyuki, Ohtsuki, Masahiko, Ono, Mitsuru, Furukawa, Hidehiko, Nagashima, Masakazu, Yoshino, Shinichi, Mabuchi, Akihiko, Sekine, Akihiro, Saito, Susumu, Takahashi, Atsushi, Tsunoda, Tatsuhiko, Nakamura, Yusuke, Yamamoto, Kazuhiko
Published in Nature genetics (01.12.2003)
Published in Nature genetics (01.12.2003)
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A functional variant in FCRL3 , encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities
Yamada, Ryo, Kochi, Yuta, Suzuki, Akari, Harley, John B, Shirasawa, Senji, Sawada, Tetsuji, Bae, Sang-Cheol, Tokuhiro, Shinya, Chang, Xiaotian, Sekine, Akihiro, Takahashi, Atsushi, Tsunoda, Tatsuhiko, Ohnishi, Yozo, Kaufman, Kenneth M, Kang, Changsoo Paul, Kang, Changwon, Otsubo, Shigeru, Yumura, Wako, Mimori, Akio, Koike, Takao, Nakamura, Yusuke, Sasazuki, Takehiko, Yamamoto, Kazuhiko
Published in Nature genetics (01.05.2005)
Published in Nature genetics (01.05.2005)
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항 HER2 항체-약물 콘쥬게이트 투여에 의한 HER2 변이암의 치료
SAITO KAKU, SERIZAWA YUI, SHIGA RYOTA, TOKUHIRO SHINYA, FUJISAKI YOSHIHIKO, SATO YUTA, JIKOH TAKAHIRO
Year of Publication 09.02.2021
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Year of Publication 09.02.2021
Patent
Fine-tuning of ENA gapmers as antisense oligonucleotides for sequence-specific inhibition
Takagi-Sato, Miho, Tokuhiro, Shinya, Kawaida, Reimi, Koizumi, Makoto
Published in Oligonucleotides (01.09.2007)
Published in Oligonucleotides (01.09.2007)
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TREATMENT OF HER2-MUTATED CANCER BY ADMINISTERING ANTI-HER2 ANTIBODY-DRUG CONJUGATE
TOKUHIRO Shinya, SERIZAWA Yui, SAITO Kaku, JIKOH Takahiro, SATO Yuta, FUJISAKI Yoshihiko, SHIGA Ryota
Year of Publication 05.12.2019
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Year of Publication 05.12.2019
Patent
Meta-analysis of the Association Between Variants in SORL1 and Alzheimer Disease
Reitz, Christiane, Cheng, Rong, Rogaeva, Ekaterina, Lee, Joseph H, Tokuhiro, Shinya, Zou, Fanggeng, Bettens, Karolien, Sleegers, Kristel, Tan, Eng King, Kimura, Ryo, Shibata, Nobuto, Arai, Heii, Kamboh, M. Ilyas, Prince, Jonathan A, Maier, Wolfgang, Riemenschneider, Matthias, Owen, Michael, Harold, Denise, Hollingworth, Paul, Cellini, Elena, Sorbi, Sandro, Nacmias, Benedetta, Takeda, Masatoshi, Pericak-Vance, Margaret A, Haines, Jonathan L, Younkin, Steven, Williams, Julie, van Broeckhoven, Christine, Farrer, Lindsay A, St George–Hyslop, Peter H, Mayeux, Richard
Published in Archives of neurology (Chicago) (01.01.2011)
Published in Archives of neurology (Chicago) (01.01.2011)
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Journal Article
SLC22A4 and RUNX1: identification of RA susceptible genes
Yamada, Ryo, Tokuhiro, Shinya, Chang, Xiotian, Yamamoto, Kazuhiko
Published in Journal of molecular medicine (Berlin, Germany) (01.09.2004)
Published in Journal of molecular medicine (Berlin, Germany) (01.09.2004)
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Journal Article
β-Amyloid-specific upregulation of stearoyl coenzyme A desaturase-1 in macrophages
Uryu, Shigeko, Tokuhiro, Shinya, Oda, Tomiichiro
Published in Biochemical and biophysical research communications (28.03.2003)
Published in Biochemical and biophysical research communications (28.03.2003)
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Journal Article
P4‐112: The sortilin‐related receptor (SORL1) influences variation in memory in late‐onset Alzheimer disease
Reitz, Christiane, Lee, Joseph, Cheng, Rong, Rogaeva, Ekaterina, Tokuhiro, Shinya, Clark, Lorraine, St. George‐Hyslop, Peter, Mayeux, Richard
Published in Alzheimer's & dementia (01.07.2009)
Published in Alzheimer's & dementia (01.07.2009)
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P4‐126: The sortilin‐related receptor (SORL1) influences variation in memory in late‐onset Alzheimer's disease
Reitz, Christiane, Lee, Joseph, Cheng, Rong, Rogaeva, Ekaterina, Tokuhiro, Shinya, Clark, Lorraine, St. George‐Hyslop, Peter, Mayeux, Richard
Published in Alzheimer's & dementia (01.07.2009)
Published in Alzheimer's & dementia (01.07.2009)
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